Potent and Selective Cathepsin L Inhibitors Do Not Inhibit Human Osteoclast Resorption in Vitro

Journal of Biological Chemistry

Volumn 276, Issue 15, 2001, Pages 11507-11511

  James, Ian E ^a   Marquis, Robert W ^a   Blake, Simon M ^a   Hwang, Shing Mei ^a   Gress, Catherine J ^a   Ru, Yu ^a   Zembryki, Denise ^a   Yamashita, Dennis S ^a   McQueney, Michael S ^a   Tomaszek, Thaddeus A ^a   Oh, Hye Ja ^a   Gowen, Maxine ^a   Veber, Daniel F ^a   Lark, Michael W ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDES; BIOASSAY; BONE; ENZYME INHIBITION;

BONE RESORPTION; OSTEOBLASTS;

BIOCHEMISTRY;

CATHEPSIN K; CATHEPSIN L; CATHEPSIN L INHIBITOR; PROTEIN INHIBITOR; UNCLASSIFIED DRUG; CATHEPSIN; CYSTEINE PROTEINASE; CYSTEINE PROTEINASE INHIBITOR; PROTEINASE;

ARTICLE; CELL ASSAY; CONTROLLED STUDY; CYTOCHEMISTRY; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; INHIBITION KINETICS; OSTEOCLAST; OSTEOLYSIS; PRIORITY JOURNAL; PROTEIN FUNCTION; CELL CULTURE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT;

BONE RESORPTION; CATHEPSINS; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; ENDOPEPTIDASES; HUMANS; OSTEOCLASTS; TUMOR CELLS, CULTURED;

EID: 0035853837     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010684200     Document Type: Article

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