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Pauli G, Malling H, Rak S, Pastorello E, Purohit A, Larsen T, Ardvisson M, Kavina A, Szaal S, Schroeder J, Vighi G et al: Clinical efficacy of subcutaneous immunotherapy in birch pollen allergic patients: A randomized, double-blind, placebo-controlled study with recombinant Bet v 1 versus nartural Bet v 1 or standard birch extract. Congress of the European Academy of Allergology and Clinical Immunology, Vienna, Austria (2006) 25:Abs 83. •• This abstract reports data from a clinical trial of a recombinant allergen in comparison with whole pollen extract, which suggest that a recombinant major allergen can substitute complex extracts in SIT.
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Tulic MK, Fiset PO, Christodoulopoulos P, Vaillancourt P, Desrosiers M, Lavigne F, Eiden J, Hamid Q: Amb a 1-immunostimulatory oligodeoxynucleotide conjugate immunotherapy decreases the nasal inflammatory response. J Allergy Clin Immunol (2004) 113(2):235-241. • The paper describes the use of DNA-allergen conjugates for the treatment of allergic rhinitis caused by ragweed pollen.
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