Modulation of IgE reactivity of allergens by site-directed mutagenesis: Potential use of hypoallergenic variants for immunotherapy

FASEB Journal

Volumn 12, Issue 2, 1998, Pages 231-242

  Ferreira, Fátima ^a   Ebner, Christof ^e   Kramer, Bettina ^a   Casari, Georg ^b   Briza, Peter ^a   Kungl, Andreas J ^c   Grimm, Rudolf ^d   Jahn Schmid, Beatrice ^e   Breiteneder, Heimo ^e   Kraft, Dietrich ^e   Breitenbach, Michael ^a   Rheinberger, Hans Jörg ^a   Scheiner, Otto ^e  

^a UNIVERSITY OF SALZBURG   (Austria)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^c Brunnerstra e 59   (Austria)

^d Hewlett Packard Analytical Group   (Germany)

^e UNIVERSITY OF VIENNA   (Austria)

Author keywords

Allergen specific T cell clones; Bet v 1 mutants; Hypoallergens; IgE binding epitopes; Major birch pollen allergen

Indexed keywords

ALLERGEN; COMPLEMENTARY DNA; GAMMA INTERFERON; IMMUNOGLOBULIN E; INTERLEUKIN 4; INTERLEUKIN 5; POLLEN ANTIGEN;

ALLERGIC REACTION; AMINO ACID SUBSTITUTION; ANAPHYLAXIS; ARTICLE; DESENSITIZATION; ESCHERICHIA COLI; HELPER CELL; IMMEDIATE TYPE HYPERSENSITIVITY; IMMUNOBLOTTING; IMMUNOMODULATION; IMMUNOPHARMACOLOGY; IMMUNOREACTIVITY; IMMUNOTHERAPY; MAST CELL; MOLECULAR CLONING; NONHUMAN; POLLEN ALLERGY; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS;

ESCHERICHIA COLI;

EID: 0031952580     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fasebj.12.2.231     Document Type: Article

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