Expansion of Polyglutamine Induces the Formation of Quasi-aggregate in the Early Stage of Protein Fibrillization

Journal of Biological Chemistry

Volumn 278, Issue 36, 2003, Pages 34717-34724

  Tanaka, Motomasa ^a   Machida, Yoko ^a   Nishikawa, Yukihiro ^b   Akagi, Takumi ^a   Hashikawa, Tsutomu ^a   Fujisawa, Tetsuro ^b   Nukina, Nobuyuki ^a  

^a RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^b RIKEN HARIMA INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTRON MICROSCOPY; MONOCLONAL ANTIBODIES; MONOMERS; ORGANIC POLYMERS; X RAY SCATTERING;

FIBRILLIZATION;

PROTEINS;

FIBRILLIN; MONOCLONAL ANTIBODY; POLYGLUTAMINE; CONGO RED; PEPTIDE; PROTEIN; RECOMBINANT PROTEIN;

ANIMAL CELL; ANTIBODY SPECIFICITY; ARTICLE; BETA SHEET; COMPLEX FORMATION; CYTOTOXICITY; ELECTRON MICROSCOPY; MOLECULAR MECHANICS; NERVE DEGENERATION; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; TARGET CELL; X RAY CRYSTALLOGRAPHY; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; CHICKEN; CHROMATOGRAPHY; ESCHERICHIA COLI; IMMUNOBLOTTING; METABOLISM; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE; RADIATION SCATTERING; TEMPERATURE; TIME; ULTRAVIOLET RADIATION; X RAY; X RAY DIFFRACTION;

ANIMALIA;

ANIMALS; ANTIBODIES, MONOCLONAL; CHICKENS; CHROMATOGRAPHY; CONGO RED; ESCHERICHIA COLI; IMMUNOBLOTTING; MICROSCOPY, ELECTRON; MODELS, MOLECULAR; PEPTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEINS; RECOMBINANT PROTEINS; SCATTERING, RADIATION; TEMPERATURE; TIME FACTORS; ULTRAVIOLET RAYS; X-RAY DIFFRACTION; X-RAYS;

EID: 0141668882     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M209852200     Document Type: Article

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