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Volumn 47, Issue 11, 2006, Pages 4810-4818

AsialoGM1-mediated IL-8 release by human corneal epithelial cells requires coexpression of TLR5

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM CHANNEL L TYPE; CALCIUM ION; FURA 2; GANGLIOTETRAOSYLCERAMIDE; INTERLEUKIN 8; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NEUTRALIZING ANTIBODY; PURINE P2Y RECEPTOR; TOLL LIKE RECEPTOR 5; VOLTAGE GATED CALCIUM CHANNEL; CALCIUM; GANGLIOSIDE GM1; PURINE P2 RECEPTOR; TLR5 PROTEIN, HUMAN;

EID: 34247150641     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.06-0250     Document Type: Article
Times cited : (16)

References (55)
  • 1
    • 1642633911 scopus 로고    scopus 로고
    • Use of silicone hydrogel contact lenses by Australian optometrists
    • Woods CA, Morgan PB. Use of silicone hydrogel contact lenses by Australian optometrists. Clin Exp Optom. 2004;87:19-23.
    • (2004) Clin Exp Optom , vol.87 , pp. 19-23
    • Woods, C.A.1    Morgan, P.B.2
  • 2
    • 0034755007 scopus 로고    scopus 로고
    • The expression of functional LPS receptor proteins CD14 and toll-like receptor 4 in human corneal cells
    • Song PI, Abraham TA, Park Y, et al. The expression of functional LPS receptor proteins CD14 and toll-like receptor 4 in human corneal cells. Invest Ophthalmol Vis Sci. 2001;42:2867-2877.
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 2867-2877
    • Song, P.I.1    Abraham, T.A.2    Park, Y.3
  • 3
    • 0141653750 scopus 로고    scopus 로고
    • Toll-like receptor 5-mediated corneal epithelial inflammatory responses to Pseudomonas aeruginosa flagellin
    • Zhang J, Xu K, Ambati B, Yu FS. Toll-like receptor 5-mediated corneal epithelial inflammatory responses to Pseudomonas aeruginosa flagellin. Invest Ophthalmol Vis Sci. 2003;44:4247-4254.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 4247-4254
    • Zhang, J.1    Xu, K.2    Ambati, B.3    Yu, F.S.4
  • 4
    • 0035374513 scopus 로고    scopus 로고
    • Cystic fibrosis pathogens activate Ca2+-dependent mitogen-activated protein kinase signaling pathways in airway epithelial cells
    • Ratner AJ, Bryan R, Weber A, et al. Cystic fibrosis pathogens activate Ca2+-dependent mitogen-activated protein kinase signaling pathways in airway epithelial cells. J Biol Chem. 2001;276:19267-19275.
    • (2001) J Biol Chem , vol.276 , pp. 19267-19275
    • Ratner, A.J.1    Bryan, R.2    Weber, A.3
  • 5
    • 0031975347 scopus 로고    scopus 로고
    • Role of flagella in pathogenesis of Pseudomonas aeruginosa pulmonary infection
    • Feldman M, Bryan R, Rajan S, et al. Role of flagella in pathogenesis of Pseudomonas aeruginosa pulmonary infection. Infect Immun. 1998;66:43-51.
    • (1998) Infect Immun , vol.66 , pp. 43-51
    • Feldman, M.1    Bryan, R.2    Rajan, S.3
  • 6
    • 0035524488 scopus 로고    scopus 로고
    • Toll-like receptors and innate immunity
    • Medzhitov R. Toll-like receptors and innate immunity. Nat Rev Immunol. 2001;1:135-145.
    • (2001) Nat Rev Immunol , vol.1 , pp. 135-145
    • Medzhitov, R.1
  • 8
    • 0030831210 scopus 로고    scopus 로고
    • A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
    • Medzhitov R, Preston-Hurlburt P, Janeway CA Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature. 1997;388:394-397.
    • (1997) Nature , vol.388 , pp. 394-397
    • Medzhitov, R.1    Preston-Hurlburt, P.2    Janeway Jr, C.A.3
  • 9
    • 0035979172 scopus 로고    scopus 로고
    • ATP transduces signals from ASGM1, a glycolipid that functions as a bacterial receptor
    • McNamara N, Khong A, McKemy D, et al. ATP transduces signals from ASGM1, a glycolipid that functions as a bacterial receptor. Proc Natl Acad Sci USA. 2001;98:9086-9091.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 9086-9091
    • McNamara, N.1    Khong, A.2    McKemy, D.3
  • 11
    • 28644442415 scopus 로고    scopus 로고
    • HIV impairs TNF-alpha release in response to Toll-like receptor 4 stimulation in human macrophages in vitro
    • Tachado SD, Zhang J, Zhu J, Patel N, Koziel H. HIV impairs TNF-alpha release in response to Toll-like receptor 4 stimulation in human macrophages in vitro. Am J Respir Cell Mol Biol. 2005;33:610-621.
    • (2005) Am J Respir Cell Mol Biol , vol.33 , pp. 610-621
    • Tachado, S.D.1    Zhang, J.2    Zhu, J.3    Patel, N.4    Koziel, H.5
  • 12
    • 2342535902 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa flagella activate airway epithelial cells through asialoGM1 and toll-like receptor 2 as well as toll-like receptor 5
    • Adamo R, Sokol S, Soong G, Gomez MI, Prince A. Pseudomonas aeruginosa flagella activate airway epithelial cells through asialoGM1 and toll-like receptor 2 as well as toll-like receptor 5. Am J Respir Cell Mol Biol. 2004;30:627-634.
    • (2004) Am J Respir Cell Mol Biol , vol.30 , pp. 627-634
    • Adamo, R.1    Sokol, S.2    Soong, G.3    Gomez, M.I.4    Prince, A.5
  • 13
    • 2942532924 scopus 로고    scopus 로고
    • TLR2 is mobilized into an apical lipid raft receptor complex to signal infection in airway epithelial cells
    • Soong G, Reddy B, Sokol S, Adamo R, Prince A. TLR2 is mobilized into an apical lipid raft receptor complex to signal infection in airway epithelial cells. J Clin Invest. 2004;113:1482-1489.
    • (2004) J Clin Invest , vol.113 , pp. 1482-1489
    • Soong, G.1    Reddy, B.2    Sokol, S.3    Adamo, R.4    Prince, A.5
  • 14
    • 0033847562 scopus 로고    scopus 로고
    • Establishment of Pseudomonas aeruginosa infection: Lessons from a versatile opportunist
    • Lyczak JB, Cannon CL, Pier GB. Establishment of Pseudomonas aeruginosa infection: lessons from a versatile opportunist. Microbes Infect. 2000;2:1051-1060.
    • (2000) Microbes Infect , vol.2 , pp. 1051-1060
    • Lyczak, J.B.1    Cannon, C.L.2    Pier, G.B.3
  • 16
    • 0011680902 scopus 로고
    • Many pulmonary pathogenic bacteria bind specifically to the carbohydrate sequence GalNAc beta 1-4Gal found in some glycolipids
    • Krivan HC, Roberts DD, Ginsburg V. Many pulmonary pathogenic bacteria bind specifically to the carbohydrate sequence GalNAc beta 1-4Gal found in some glycolipids. Proc Natl Acad Sci USA. 1988;85:6157-6161.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 6157-6161
    • Krivan, H.C.1    Roberts, D.D.2    Ginsburg, V.3
  • 17
    • 0032081281 scopus 로고    scopus 로고
    • Activation of NF-kappaB by adherent Pseudomonas aeruginosa in normal and cystic fibrosis respiratory epithelial cells
    • DiMango E, Ratner AJ, Bryan R, Tabibi S, Prince A. Activation of NF-kappaB by adherent Pseudomonas aeruginosa in normal and cystic fibrosis respiratory epithelial cells. J Clin Invest. 1998;101:2598-2605.
    • (1998) J Clin Invest , vol.101 , pp. 2598-2605
    • DiMango, E.1    Ratner, A.J.2    Bryan, R.3    Tabibi, S.4    Prince, A.5
  • 18
    • 0034043956 scopus 로고    scopus 로고
    • Inhibition of lipopolysaccharide- induced signal transduction in endotoxin-tolerized mouse macrophages: Dysregulation of cytokine, chemokine, and toll-like receptor 2 and 4 gene expression
    • Medvedev AE, Kopydlowski KM, Vogel SN. Inhibition of lipopolysaccharide- induced signal transduction in endotoxin-tolerized mouse macrophages: dysregulation of cytokine, chemokine, and toll-like receptor 2 and 4 gene expression. J Immunol. 2000;164:5564-5574.
    • (2000) J Immunol , vol.164 , pp. 5564-5574
    • Medvedev, A.E.1    Kopydlowski, K.M.2    Vogel, S.N.3
  • 19
    • 0034886143 scopus 로고    scopus 로고
    • Toll-like receptors: Critical proteins linking innate and acquired immunity
    • Akira S, Takeda K, Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat Immunol. 2001;2:675-680.
    • (2001) Nat Immunol , vol.2 , pp. 675-680
    • Akira, S.1    Takeda, K.2    Kaisho, T.3
  • 21
    • 0035909372 scopus 로고    scopus 로고
    • Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
    • Alexopoulou L, Holt AC, Medzhitov R, Flavell RA. Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature. 2001;413:732-738.
    • (2001) Nature , vol.413 , pp. 732-738
    • Alexopoulou, L.1    Holt, A.C.2    Medzhitov, R.3    Flavell, R.A.4
  • 22
    • 0033574415 scopus 로고    scopus 로고
    • Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction
    • Chow JC, Young DW, Golenbock DT, Christ WJ, Gusovsky F. Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction. J Biol Chem. 1999;274:10689-10692.
    • (1999) J Biol Chem , vol.274 , pp. 10689-10692
    • Chow, J.C.1    Young, D.W.2    Golenbock, D.T.3    Christ, W.J.4    Gusovsky, F.5
  • 23
    • 0034723186 scopus 로고    scopus 로고
    • Mouse toll-like receptor 4.MD-2 complex mediates lipopolysaccharide-mimetic signal transduction by Taxol
    • Kawasaki K, Akashi S, Shimazu R, Yoshida T, Miyake K, Nishijima M. Mouse toll-like receptor 4.MD-2 complex mediates lipopolysaccharide-mimetic signal transduction by Taxol. J Biol Chem. 2000;275:2251-2254.
    • (2000) J Biol Chem , vol.275 , pp. 2251-2254
    • Kawasaki, K.1    Akashi, S.2    Shimazu, R.3    Yoshida, T.4    Miyake, K.5    Nishijima, M.6
  • 24
    • 0035953543 scopus 로고    scopus 로고
    • The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
    • Hayashi F, Smith KD, Ozinsky A, et al. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature. 2001;410:1099-1103.
    • (2001) Nature , vol.410 , pp. 1099-1103
    • Hayashi, F.1    Smith, K.D.2    Ozinsky, A.3
  • 25
    • 0034619794 scopus 로고    scopus 로고
    • A Toll-like receptor recognizes bacterial DNA
    • Hemmi H, Takeuchi O, Kawai T, et al. A Toll-like receptor recognizes bacterial DNA. Nature. 2000;408:740-745.
    • (2000) Nature , vol.408 , pp. 740-745
    • Hemmi, H.1    Takeuchi, O.2    Kawai, T.3
  • 26
    • 13944271838 scopus 로고    scopus 로고
    • Activation of toll-like receptor (TLR)2, TLR4, and TLR9 in the mammalian cornea induces MyD88-dependent corneal inflammation
    • Johnson AC, Heinzel FP, Diaconu E, et al. Activation of toll-like receptor (TLR)2, TLR4, and TLR9 in the mammalian cornea induces MyD88-dependent corneal inflammation. Invest Ophthalmol Vis Sci. 2005;46:589-595.
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 589-595
    • Johnson, A.C.1    Heinzel, F.P.2    Diaconu, E.3
  • 27
    • 4344705045 scopus 로고    scopus 로고
    • Intracellularly expressed TLR2s and TLR4s contribution to an immunosilent environment at the ocular mucosal epithelium
    • Ueta M, Nochi T, Jang MH, et al. Intracellularly expressed TLR2s and TLR4s contribution to an immunosilent environment at the ocular mucosal epithelium. J Immunol. 2004;173:3337-3347.
    • (2004) J Immunol , vol.173 , pp. 3337-3347
    • Ueta, M.1    Nochi, T.2    Jang, M.H.3
  • 28
    • 0032489443 scopus 로고    scopus 로고
    • Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane
    • Okamoto T, Schlegel A, Scherer PE, Lisanti MP. Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane. J Biol Chem. 1998;273:5419-5922.
    • (1998) J Biol Chem , vol.273 , pp. 5419-5922
    • Okamoto, T.1    Schlegel, A.2    Scherer, P.E.3    Lisanti, M.P.4
  • 29
    • 0027434932 scopus 로고
    • Evidence for asialo GM1 as a corneal glycolipid receptor for Pseudomonas aeruginosa adhesion
    • Hazlett LD, Masinick S, Barren R, Rosol K. Evidence for asialo GM1 as a corneal glycolipid receptor for Pseudomonas aeruginosa adhesion. Infect Immun. 1993;61:5164-5173.
    • (1993) Infect Immun , vol.61 , pp. 5164-5173
    • Hazlett, L.D.1    Masinick, S.2    Barren, R.3    Rosol, K.4
  • 30
    • 0028819297 scopus 로고
    • Pseudomonas aeruginosa infection of the cornea and asialo GM1
    • Zhao Z, Panjwani N. Pseudomonas aeruginosa infection of the cornea and asialo GM1. Infect Immun. 1995;63:353-355.
    • (1995) Infect Immun , vol.63 , pp. 353-355
    • Zhao, Z.1    Panjwani, N.2
  • 31
    • 0028026815 scopus 로고
    • Pili and lipopolysaccharide of Pseudomonas aeruginosa bind to the glycolipid asialo GM1
    • Gupta SK, Berk RS, Masinick S, Hazlett LD. Pili and lipopolysaccharide of Pseudomonas aeruginosa bind to the glycolipid asialo GM1. Infect Immun. 1994;62:4572-4579.
    • (1994) Infect Immun , vol.62 , pp. 4572-4579
    • Gupta, S.K.1    Berk, R.S.2    Masinick, S.3    Hazlett, L.D.4
  • 32
    • 18244377417 scopus 로고    scopus 로고
    • Internalization of Pseudomonas aeruginosa is mediated by lipid rafts in contact lens-wearing rabbit and cultured human corneal epithelial cells
    • Yamamoto N, Petroll MW, Cavanagh HD, Jester JV. Internalization of Pseudomonas aeruginosa is mediated by lipid rafts in contact lens-wearing rabbit and cultured human corneal epithelial cells. Invest Ophthalmol Vis Sci. 2005;46:1348-1355.
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 1348-1355
    • Yamamoto, N.1    Petroll, M.W.2    Cavanagh, H.D.3    Jester, J.V.4
  • 33
    • 0028953829 scopus 로고
    • An SV40-immortalized human corneal epithelial cell line and its characterization
    • Araki-Sasaki K, Ohashi Y, Sasabe T, et al. An SV40-immortalized human corneal epithelial cell line and its characterization. Invest Ophthalmol Vis Sci. 1995;36:614-621.
    • (1995) Invest Ophthalmol Vis Sci , vol.36 , pp. 614-621
    • Araki-Sasaki, K.1    Ohashi, Y.2    Sasabe, T.3
  • 34
    • 0034918894 scopus 로고    scopus 로고
    • Fleiszig SM, Arora SK, Van R, Ramphal R. FlhA, a component of the flagellum assembly apparatus of Pseudomonas aeruginosa, plays a role in internalization by corneal epithelial cells. Infect Immun. 2001;69:4931-4937.
    • Fleiszig SM, Arora SK, Van R, Ramphal R. FlhA, a component of the flagellum assembly apparatus of Pseudomonas aeruginosa, plays a role in internalization by corneal epithelial cells. Infect Immun. 2001;69:4931-4937.
  • 35
    • 0001201182 scopus 로고    scopus 로고
    • Corneal responses to infection
    • Krachmer JH, Mannis MJ, Holland EJ, eds, St. Louis: Mosby;
    • Williams JM Fini ME, Cousins SW, Repose JS. Corneal responses to infection. In: Krachmer JH, Mannis MJ, Holland EJ, eds. Cornea. St. Louis: Mosby; 1997:128-162.
    • (1997) Cornea , pp. 128-162
    • Williams, J.M.1    Fini, M.E.2    Cousins, S.W.3    Repose, J.S.4
  • 36
    • 0000638543 scopus 로고
    • Cell biology of the corneal epithelium
    • Albert DM, Jacobiec FA, eds, Philadelphia: WB Saunders;
    • Gipson I, Grill SM. Cell biology of the corneal epithelium. In: Albert DM, Jacobiec FA, eds. Principles and Practice of Ophthalmology. Philadelphia: WB Saunders; 1994:3-16.
    • (1994) Principles and Practice of Ophthalmology , pp. 3-16
    • Gipson, I.1    Grill, S.M.2
  • 37
    • 0024469313 scopus 로고
    • The relative risk of ulcerative keratitis among users of daily-wear and extended-wear soft contact lenses: A case-control study. Microbial Keratitis Study Group
    • Schein OD, Glynn RJ, Poggio EC, Seddon JM, Kenyon KR. The relative risk of ulcerative keratitis among users of daily-wear and extended-wear soft contact lenses: a case-control study. Microbial Keratitis Study Group. N Engl J Med. 1989;321:773-778.
    • (1989) N Engl J Med , vol.321 , pp. 773-778
    • Schein, O.D.1    Glynn, R.J.2    Poggio, E.C.3    Seddon, J.M.4    Kenyon, K.R.5
  • 38
    • 0029046407 scopus 로고
    • Epidemiology of Pseudomonas aeruginosa keratitis in contact lens wearers
    • Stapleton F, Dart JK, Seal DV, Matheson M. Epidemiology of Pseudomonas aeruginosa keratitis in contact lens wearers. Epidemiol Infect. 1995;114:395-402.
    • (1995) Epidemiol Infect , vol.114 , pp. 395-402
    • Stapleton, F.1    Dart, J.K.2    Seal, D.V.3    Matheson, M.4
  • 40
    • 10344224055 scopus 로고    scopus 로고
    • Acute effects of parainfluenza virus on epithelial electrolyte transport
    • Kunzelmann K, Konig J, Sun J, et al. Acute effects of parainfluenza virus on epithelial electrolyte transport. J Biol Chem. 2004;279:48760-48766.
    • (2004) J Biol Chem , vol.279 , pp. 48760-48766
    • Kunzelmann, K.1    Konig, J.2    Sun, J.3
  • 42
    • 0031596088 scopus 로고    scopus 로고
    • + mobilization in bovine corneal endothelial cells by P2 purinergic receptors
    • + mobilization in bovine corneal endothelial cells by P2 purinergic receptors. Curr Eye Res. 1998;17:994-1004.
    • (1998) Curr Eye Res , vol.17 , pp. 994-1004
    • Srinivas, S.P.1    Yeh, J.C.2    Ong, A.3    Bonanno, J.A.4
  • 43
    • 0031754497 scopus 로고    scopus 로고
    • Receptors for purines and pyrimidines
    • Ralevic V, Burnstock G. Receptors for purines and pyrimidines. Pharmacol Rev. 1998;50:413-492.
    • (1998) Pharmacol Rev , vol.50 , pp. 413-492
    • Ralevic, V.1    Burnstock, G.2
  • 44
    • 16844363317 scopus 로고    scopus 로고
    • P2Y receptors play a critical role in epithelial cell communication and migration
    • Klepeis VE, Weinger I, Kaczmarek E, Trinkaus-Randall V. P2Y receptors play a critical role in epithelial cell communication and migration. J Cell Biochem. 2004;93:1115-1133.
    • (2004) J Cell Biochem , vol.93 , pp. 1115-1133
    • Klepeis, V.E.1    Weinger, I.2    Kaczmarek, E.3    Trinkaus-Randall, V.4
  • 46
    • 23244437654 scopus 로고    scopus 로고
    • Innate immune responses to infection
    • quiz 250
    • Tosi MF. Innate immune responses to infection. J Allergy Clin Immunol. 2005;116:241-249; quiz 250.
    • (2005) J Allergy Clin Immunol , vol.116 , pp. 241-249
    • Tosi, M.F.1
  • 47
    • 0028881698 scopus 로고
    • Diverse Pseudomonas aeruginosa gene products stimulate respiratory epithelial cells to produce interleukin-8
    • DiMango E, Zar HJ, Bryan R, Prince A. Diverse Pseudomonas aeruginosa gene products stimulate respiratory epithelial cells to produce interleukin-8. J Clin Invest. 1995;96:2204-2210.
    • (1995) J Clin Invest , vol.96 , pp. 2204-2210
    • DiMango, E.1    Zar, H.J.2    Bryan, R.3    Prince, A.4
  • 48
    • 0035425495 scopus 로고    scopus 로고
    • Innate immune responses of epithelial cells following infection with bacterial pathogens
    • Philpott DJ, Girardin SE, Sansonetti PJ. Innate immune responses of epithelial cells following infection with bacterial pathogens. Curr Opin Immunol. 2001;13:410-416.
    • (2001) Curr Opin Immunol , vol.13 , pp. 410-416
    • Philpott, D.J.1    Girardin, S.E.2    Sansonetti, P.J.3
  • 49
    • 0035863730 scopus 로고    scopus 로고
    • Flagellin, a novel mediator of Salmonella-induced epithelial activation and systemic inflammation: I kappa B alpha degradation, induction of nitric oxide synthase, induction of proinflammatory mediators, and cardiovascular dysfunction
    • Eaves-Pyles T, Murthy K, Liaudet L, Virag L, Ross G, Soriano FG. Flagellin, a novel mediator of Salmonella-induced epithelial activation and systemic inflammation: I kappa B alpha degradation, induction of nitric oxide synthase, induction of proinflammatory mediators, and cardiovascular dysfunction. J Immunol. 2001;166:1248-1260.
    • (2001) J Immunol , vol.166 , pp. 1248-1260
    • Eaves-Pyles, T.1    Murthy, K.2    Liaudet, L.3    Virag, L.4    Ross, G.5    Soriano, F.G.6
  • 50
    • 0035881675 scopus 로고    scopus 로고
    • Cutting edge: Bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression
    • Gewirtz AT, Navas TA, Lyons S, Godowski PJ, Madara JL. Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression. J Immunol. 2001;167:1882-1885.
    • (2001) J Immunol , vol.167 , pp. 1882-1885
    • Gewirtz, A.T.1    Navas, T.A.2    Lyons, S.3    Godowski, P.J.4    Madara, J.L.5
  • 52
    • 2942560322 scopus 로고    scopus 로고
    • MEK is a key modulator for TLR5-induced interleukin-8 and MIP3alpha gene expression in non-transfromed human colonic epithelial cells
    • Rhee SH, Keates AC, Moyer MP, Pothoulakis C. MEK is a key modulator for TLR5-induced interleukin-8 and MIP3alpha gene expression in non-transfromed human colonic epithelial cells. J Biol Chem. 2004;279:25179-25188.
    • (2004) J Biol Chem , vol.279 , pp. 25179-25188
    • Rhee, S.H.1    Keates, A.C.2    Moyer, M.P.3    Pothoulakis, C.4
  • 53
    • 4844224383 scopus 로고    scopus 로고
    • Flagellin acting via TLR5 is the major activator of key signaling pathways leading to NF-kappa B and proinflammatory gene program activation in intestina; epithelial cells
    • Tallant T, Deb A, Kar N, Lupica J, de Veer MJ, DiDonato JA. Flagellin acting via TLR5 is the major activator of key signaling pathways leading to NF-kappa B and proinflammatory gene program activation in intestina; epithelial cells. BMC Microbiol. 2004;4:33.
    • (2004) BMC Microbiol , vol.4 , pp. 33
    • Tallant, T.1    Deb, A.2    Kar, N.3    Lupica, J.4    de Veer, M.J.5    DiDonato, J.A.6
  • 54
    • 0038185316 scopus 로고    scopus 로고
    • Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharride in human hepatic stellate cells
    • Paik YH, Schwabe RF, Bataller R, Russo, Jobin C, Brenner DA. Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharride in human hepatic stellate cells. Hepatology. 2003;37:1043-1055.
    • (2003) Hepatology , vol.37 , pp. 1043-1055
    • Paik, Y.H.1    Schwabe, R.F.2    Bataller, R.3    Russo4    Jobin, C.5    Brenner, D.A.6
  • 55
    • 4644310244 scopus 로고    scopus 로고
    • Innate immune response of corneal epithelial cells to Staphylococcus aureus infectio: Role of peptidoglycan in stimulationg proinflammatory cytokine secretion
    • Kumar A, Shaang J, Yu FS. Innate immune response of corneal epithelial cells to Staphylococcus aureus infectio: role of peptidoglycan in stimulationg proinflammatory cytokine secretion. Invest Ophthalmol Vis Sci. 2004;45:3513-3522.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 3513-3522
    • Kumar, A.1    Shaang, J.2    Yu, F.S.3


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