Lower specific micronutrient intake in colorectal cancer patients with tumors presenting promoter hypermethylation in p16INK4a, p14 ARF and hMLH1

Anticancer Research

Volumn 27, Issue 2, 2007, Pages 1151-1156

  Mas, Sergi ^a   Lafuente, M Jose ^a   Crescenti, Anna ^a   Trias, Manuel ^b   Ballesta, Antonio ^c   Molina, Rafael ^c   Zheng, Shichun ^d   Wiencke, John K ^d   Lafuente, Amalia ^a,e  

^a UNIVERSITY OF BARCELONA   (Spain)

^b Hospital St Pau   (Spain)

^c HOSPITAL CLÍNIC   (Spain)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Colorectal cancer; DNA hypermethylation; Folate; Micronutrients; Vitamin

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); FOLIC ACID; POTASSIUM; PROTEIN MLH1; PROTEIN P14ARF; PROTEIN P16INK4A; RETINOL; THIAMINE;

ARTICLE; CANCER RISK; CANCER STAGING; COLORECTAL CANCER; CONTROLLED STUDY; DEMOGRAPHY; DNA POLYMORPHISM; FEMALE; GENE FREQUENCY; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; METHYLATION; NUTRIENT UPTAKE; PATHOGENESIS; PRIORITY JOURNAL;

ALLELES; CARRIER PROTEINS; CASE-CONTROL STUDIES; COLORECTAL NEOPLASMS; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DIET; DNA METHYLATION; FEMALE; HUMANS; MALE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MICRONUTRIENTS; NUCLEAR PROTEINS; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); TUMOR SUPPRESSOR PROTEIN P14ARF;

EID: 34247127933     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Potter JD: Colorectal cancer: molecules and populations. J Natl Cancer Inst 91: 916-932, 1999.
2. Steinmetz KA and Potter JD: Vegetables, fruits and cancer prevention: a review. J Am Diet Assoc 96: 1027-1039, 1996.
3. Laso N, Mas S, Lafuente MJ, Casterarad X, Trias M, Ballesta A, Molina R, Salas J, Ascaso C, Zheng S, Wiencke JK and Lafuente A: Decrease in specific micronutrient intake in colorectal cancer patients with tumors presenting K-ras mutation. Anticancer Res 24: 2011-2020, 2004.
4. Feinberg AP and Vogelstein B: Alterations in DNA methylation in human colon neoplasia. Semin Surg Oncol 3: 149-151, 1987.
5. Herman JG and Baylin SB: Gene silencing in cancer in association with promoter hypermethylation. N Eng J Med 349: 2042-2054, 2003.
6. Warnecke PM and Bestor TH: Cytosine methylation in human cancer. Curr Opin Oncol 12: 68-73, 2000.
7. Bariol C, Suter C, Cheong K, Ku SL, Meagher A, Hawkins N and Ward R: Relationship between hypomethylation and CpG island methylation in colorectal neoplasia. Am J Pathol 162: 1361-1371, 2003.
8. Davis CD and Uthus EO: DNA methylation, cancer susceptibility and nutrient interactions. Exp Biol Med 229: 988-995, 2004.
9. Slattery ML, Potter JD, Samowitz W, Schaffer D and Leppert M: Methylenetetrahydrofolate reductase, diet and risk of colon cancer. Cancer Epidemiol Biomark Prev 8: 513-518, 1999.
10. Stern LL, Mason JB, Selhub J and Choi SW: Genomic DNA hypomethylation, a characteristic of most cancers, is present in peripheral leukocytes of individuals who are homozygous for the C677T polymorphism in the methylenetetrahydrofolate reductase gene. Cancer Epidemiol Biomark Prev 9: 846-853, 2000.
11. Paz MF, Avila S, Fraga MF, Pollan M, Capella G, Peinado MA, Sanchez-Cespedes M, Herman JG and Esteller M: Germ-line variants in methyl-group metabolism genes and susceptibility to DNA methylation in normal tissues and human primary tumors. Cancer Res 62: 4519-4524, 2002.
12. Friso S, Choi SW, Girelli D, Mason JB, Dolnikowski GG, Bagley PJ, Olivieri O, Jacques PF, Rosenberg IH, Corrocher R and Selhub JA: A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status. Proc Natl Acd Sci USA 99: 5606-5611, 2002.
13. INK4a in anatomic and gender specific subtypes of sporadic colorectal cancer. Cancer Epidemiol Biomark Prev 8: 501-506, 1999.
14. ARF locus with reduced mRNA expression in colorectal cancer cell lines and clinicopathological features in primary tumors. Carcinogenesis 21: 2057-2064, 2000.
15. Lafuente MJ, Casterad X, Trias M, Ascaso C, Molina R, Ballesta A, Zheng S, Wiencke JK and Lafuente A: NAD(P)H: quinone oxidoreductase-dependent risk for colorectal cancer and its association with the presence of K-ras mutations in tumors. Carcinogenesis 21: 1813-1819, 2000.
16. Laso N, Lafuente MJ, Mas S, Trias M, Ascaso C, Molina R, Ballesta A and Lafuente A: Glutatgione S-transferase (GSTM1 and GSTT1)-dependent risk for colorectal cancer. Anticancer Res 22: 3399-3404, 2002.
17. Herman JG, Graff JR, Myohanen S, Nelkin BD and Baylin SB: Methylation-specific PCR; a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci USA 93: 9821-9826, 1996.
18. Benito E, Stiggelbout A, Bosch FX, Obrador A, Kaldor J, Mulet M and Munoz N: Nutritional factors in colorectal cancer risk: a case control study in Majorca. Int J Cancer 49: 161-167, 1991.
19. Toyota M, Ahuja N, Ohe-Toyota M, Herman JG, Baylin SB and Issa JP: CpG island methylator phenotype in colorectal cancer. Proc Natl Acad Sci USA 96: 8681-8686, 1999.
20. Hawkins N, Norrie M, Cheong K, Mokany E, Ku SL, Meagher A, O'Connor T and Ward R: CpG methylation in sporadic colorectal cancers and its relationship to microsatellite instability. Gastroenterology 122: 1376-1387, 2002.
21. van Rijnsoever M, Grieu F, Elsaleh H, Joseph D and Iacopetta B: Characterization of colorectal cancers showing hypermethylation at multiple CpG islands. Gut 6: 797-802, 2002.
22. Kawakami K, Rsuzkiewicz A, Bennet G, Moore J, Watanabe G and Iacopetta B: The folate pool in colorectal cancer is associated with DNA hypermethylation and with a polymorphism in methylenetetrahydrofolate reductase. Clin Cancer Res 9: 5860-5865, 2003.
23. Kono S and Chen K: Genetic polymorphisms of methylenetetrahydrofolate reductase and colorectal cancer and adenoma. Cancer Sci 96: 535-542, 2005.
24. Kim YI: Folate and DNA methylation: a mechanistic link between folate deficiency and colorectal cancer? Cancer Epidemiol Biomark Prev 13: 511-519, 2004.
25. Slattery ML, Curtin K, Anderson K, Ma KN, Edwards S, Leppert M, Potter J, Schaffer D and Samowitz WS: Association between dietary intake and Ki-ras mutations in colon tumors: a population-based study. Cancer Res 60: 6395-6941, 2000.
26. Fenech M: The role of folic acid and vitamin B12 in genomic stability of human cells. Mutat Res 475: 57-67, 2001.
27. van Engeland M, Weijenberg MP, Roemen GM , Brink M, de Bruine AP, Goldohm RA, van de Brandt PA, Baylin SB, Goeij AF and Heman JG: Effects of dietary folate and alcohol intake on promoter methylation in sporadic colorectal cancer: the Netherlands cohort study on diet and cancer. Cancer Res 63: 3133-3137, 2003.
28. Robinson IB and Dokmanovic M: Induction of senescence-associated growth inhibitors in the tumor-suppressive function of retinoids. J Cell Biochem 88: 83-94, 2003.
29. Johanning GL and Piyathilake CJ: Retinoids and epigenetic silencing in cancer. Nutr Rev 61: 284-289, 2003.
30. Di Croce L, Raker VA, Corsaro M, Fazi F, Fanelli M, Faretta M, Fuks F, Lo Coco F, Kouzarides T, Nervi C, Minucci S and Pelicci PG: Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor. Science 295: 1079-1082, 2002.
31. Sirchia SM, Ren M, Pili R, Sironi E, Somenzi G, Ghidoni R, Toma S, Nicolo G and Sacchi N: Endogenous reactivation of the RARβ2 tumor supressor gene epigenetically silenced in breast cancer. Cancer Res 82: 2455-2461, 2002.
32. Esteller M: Hypermethylation-associated inactivation of the cellular retinol binding protein 1 gene in human cancer. Cancer Res 62: 5902-5905, 2002.
33. Rowling MJ, McMullen MH and Schalinske KL: Vitamin A and its derivates induce hepatic glycine methyltransferase and hypomethylation of DNA in rats. J Nutr 132: 365-369, 2002.
34. Comin-Anduix B, Boren J, Martinez S, Moro C, Centelles JJ, Trebukhina R, Petushok N, Lee WN, Boros LG and Cascante M: The effect of thiamine supplementation on tumour proliferation. A metabolic control analysis study. Eur J Biochem 268: 4177-4182, 2001.
35. Oppenheim EW, Adelman C, Liu X and Stover PJ: Heavy chain ferritin enhances serine hydroxymethyltransferase expression and de novo thymidine biosynthesis. J Biol Chem 276: 19855-19861, 2001.
36. Stover PJ and Garza C: Bringing individuality to public health recommendations. J Nutr 132: 2476S-2480S, 2002.