Anti-GM1 antibodies cause complement-mediated disruption of sodium channel clusters in peripheral motor nerve fibers

Journal of Neuroscience

Volumn 27, Issue 15, 2007, Pages 3956-3967

  Susuki, Keiichiro ^a,b   Rasband, Matthew N ^b   Tohyama, Koujiro ^c   Koibuchi, Katsura ^a   Okamoto, Saori ^a   Funakoshi, Kei ^a   Hirata, Koichi ^a   Baba, Hiroko ^d   Yuki, Nobuhiro ^a  

^a DOKKYO MEDICAL UNIVERSITY   (Japan)

^b UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^c IWATE MEDICAL UNIVERSITY   (Japan)

^d TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

Autoantibodies; Complement; Ganglioside; Guillain Barr syndrome; Node of Ranvier; Sodium channel

Indexed keywords

AUTOANTIBODY; GANGLIOSIDE GM1; GANGLIOSIDE GM1 AUTOANITIBODY; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPLEMENT DEPENDENT CYTOTOXICITY; CONTROLLED STUDY; DEMYELINATING NEUROPATHY; LIMB WEAKNESS; MALE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RANVIER NODE; SCHWANN CELL;

ANIMALS; AUTOANTIBODIES; COMPLEMENT SYSTEM PROTEINS; G(M1) GANGLIOSIDE; MALE; NERVE FIBERS; PERIPHERAL NERVES; RABBITS; RANVIER'S NODES; SODIUM CHANNELS;

EID: 34247099876     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4401-06.2007     Document Type: Article

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