βIVΣ1 spectrin stabilizes the nodes of Ranvier and axon initial segments

Journal of Cell Biology

Volumn 166, Issue 7, 2004, Pages 983-990

  Lacas Gervais, Sandra ^a   Guo, Jun ^b   Strenzke, Nicola ^c   Scarfone, Eric ^d   Kolpe, Melanie ^a   Jahkel, Monika ^a   De Camilli, Pietro ^b   Moser, Tobias ^c   Rasband, Matthew N ^e   Solimena, Michele ^a  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF GÖTTINGEN   (Germany)

^d CNRS   (France)

^e UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

Cerebellum; Cochlea; Cytoskeleton; Deafness; Sciatic nerve

Indexed keywords

ACTIN; ANKYRIN; GAMMA TUBULIN; PLECKSTRIN; SPECTRIN; VOLTAGE GATED SODIUM CHANNEL; ANK3 PROTEIN, RAT; BETAIV SPECTRIN; ISOPROTEIN; NERVE PROTEIN; SODIUM CHANNEL;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; COCHLEAR NERVE; CYTOSKELETON; ELECTRON MICROSCOPY; EVOKED BRAIN STEM AUDITORY RESPONSE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MOUSE; MYELINATION; NERVE CONDUCTION; NEUROPATHY; NONHUMAN; PRIORITY JOURNAL; RANVIER NODE; SEQUENCE HOMOLOGY; ANIMAL; AUDITORY NERVOUS SYSTEM; CELL MEMBRANE; CELL ORGANELLE; CONGENITAL MALFORMATION; EVOKED AUDITORY RESPONSE; FEMALE; GENETICS; GROWTH, DEVELOPMENT AND AGING; HEARING LOSS; MALE; METABOLISM; MOUSE MUTANT; NERVE FIBER; NERVOUS SYSTEM; NEWBORN; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PRENATAL DEVELOPMENT; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE;

ANIMALIA;

ANIMALS; ANIMALS, NEWBORN; ANKYRINS; AUDITORY PATHWAYS; AXONS; CELL MEMBRANE; COCHLEAR NERVE; EVOKED POTENTIALS, AUDITORY; FEMALE; HEARING LOSS; MALE; MICE; MICE, KNOCKOUT; MICROSCOPY, ELECTRON, TRANSMISSION; NERVE TISSUE PROTEINS; NERVOUS SYSTEM; ORGANELLES; PROTEIN ISOFORMS; RANVIER'S NODES; SODIUM CHANNELS; SPECTRIN;

EID: 4644286228     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200408007     Document Type: Article

References (22)

1. Bennett, V., and P.J. Stenbuck. 1979. Identification and partial purification of ankyrin, the high affinity membrane attachment site for human erythrocyte spectrin. J. Biol. Chem. 254:2533-2541.
2. Bennett, V., and A.J. Baines. 2001. Spectrin and ankyrin-based pathways: metazoan inventions for integrating cells into tissues. Physiol. Rev. 81:1353-1392.
3. Berghs, S., D. Aggujaro, R. Dirkx Jr., E. Maksimova, P. Stabach, J.M. Hermel, J.P. Zhang, W. Philbrick, V. Slepnev, T. Ort, and M. Solimena. 2000. βIV spectrin, a new spectrin localized at axon initial segments and nodes of ranvier in the central and peripheral nervous system. J. Cell Biol. 151:985-1002.
4. Berghs, S., F. Ferracci, E. Maksimova, S. Gleason, N. Leszczynski, M. Butler, P. De Camilli, and M. Solimena. 2001. Autoimmunity to βIV spectrin in paraneoplastic lower motor neuron syndrome. Proc. Natl. Acad. Sci. USA. 98:6945-6950.
5. De Camilli, P., R. Cameron, and P. Greengard. 1983. Synapsin I (protein I), a nerve terminal-specific phosphoprotein. I. Its general distribution in synapses of the central and peripheral nervous system demonstrated by immunofluorescence in frozen and plastic sections. J. Cell Biol. 96:1337-1354.
6. De Matteis, M.A., and J.S. Morrow. 2000. Spectrin tethers and mesh in the biosynthetic pathway. J. Cell Sci. 113:2331-2343.
7. Hood, J.D. 1950. Studies in auditory fatigue and adaptation. Acta Otolaryngol. Suppl. 92:1-57.
8. Jenkins, S.M., and V. Bennett. 2001. Human auditory evoked potentials: possible brain stem components detected on the scalp. Science. 167:1517-1518.
9. Jewett, D.L., M.N. Romano, and J.S. Williston. 1970. Human auditory evoked potentials: possible brain stem components detected on the scalp. Science. 167:1517-1518.
10. Komada, M., and P. Soriano. 2002. βIV-spectrin regulates sodium channel clustering through ankyrin-G at axon initial segments and nodes of Ranvier. J. Cell Biol. 156:337-348.
11. Marchesi, V.T. 1985. Stabilizing infrastructure of cell membranes. Annu. Rev. Cell Biol. 1:531-561.
12. Marchesi, V.T., and E. Steers Jr. 1968. Selective solubilization of a protein component of the red cell membrane. Science. 159:203-204.
13. Parkinson, N.J., C.L. Olsson, J.L. Hallows, J. McKee-Johnson, B.P. Keogh, K. Noben-Trauth, S.G. Kujawa, and B.L. Tempel. 2001. Mutant β-spectrin 4 causes auditory and motor neuropathies in quivering mice. Nat. Genet. 29:61-65.
14. Poliak, S., and E. Peles. 2003. The local differentiation of myelinated axons at nodes of Ranvier. Nat. Rev. Neurosci. 4:968-980.
15. + channels in spinal cord. J. Comp. Neurol. 429:166-176.
16. Rasband, M.N., E. Peles, J.S. Trimmer, S.R. Levinson, S.E. Lux, and P. Shrager. 1999. Dependence of nodal sodium channel clustering on paranodal axoglial contact in the developing CNS. J. Neurosci. 19:7516-7528.
17. Robertson, J.D. 1957. The ultrastructure of nodes of Ranvier in frog nerve fibres. J. Physiol. 137:8-9.
18. Salzer, J.L. 2003. Polarized domains of myelinated axons. Neuron. 40:297-318.
19. Suter, U., and S.S. Scherer. 2003. Disease mechanisms in inherited neurophathies. Nat. Rev. Neurosci. 4:714-726.
20. Traka, M., L. Goutebroze, N. Denisenko, M. Bessa, A. Nifli, S. Havaki, Y. Iwakura, F. Fukamauchi, K. Watanabe, B. Soliven, et al. 2003. Association of TAG-1 with Caspr2 is essential for the molecular organization of juxta-paranodal regions of myelinated fibers. J. Cell Biol. 162:1161-1172.
21. Tse, W.T., J. Tang, O. Jin, C. Korsgren, K.M. John, A.L. Kung, B. Gwynn, L.L. Peters, and S.E. Lux. 2001. A new spectrin, βIV, has a major truncated isoform that associates with promyelocytic leukemia protein nuclear bodies and the nuclear matrix. J. Biol. Chem. 276:23974-23985.
22. Zimmermann, H. 1996. Accumulation of synaptic vesicle proteins and cytoskeletal specializations at the peripheral node of Ranvier. Microsc. Res. Tech. 34:462-473.