메뉴 건너뛰기




Volumn 25, Issue 7, 2007, Pages 1998-2008

A quantitative trait locus on chromosome 18 is a critical determinant of excitotoxic cell death susceptibility

Author keywords

C57BL 6J; FVB NJ; Interval specific congenic strain; Mouse; Quantitative trait locus; Recombinant progeny testing

Indexed keywords

KAINIC ACID;

EID: 34147219224     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2007.05443.x     Document Type: Article
Times cited : (18)

References (56)
  • 1
    • 0037827756 scopus 로고    scopus 로고
    • The neuroprotective effects of heat shock protein 27 overexpression in transgenic animals against kainate-induced seizures and hippocampal cell death
    • Akbar, M.T., Lundberg, A.M., Liu, K., Vidyadaran, S., Wells, K.E., Dolatshad, H., Wynn, S., Wells, D.J., Latchman, D.S. & de Belleroche, J. (2003) The neuroprotective effects of heat shock protein 27 overexpression in transgenic animals against kainate-induced seizures and hippocampal cell death. J. Biol. Chem., 278, 19956-19965.
    • (2003) J. Biol. Chem , vol.278 , pp. 19956-19965
    • Akbar, M.T.1    Lundberg, A.M.2    Liu, K.3    Vidyadaran, S.4    Wells, K.E.5    Dolatshad, H.6    Wynn, S.7    Wells, D.J.8    Latchman, D.S.9    de Belleroche, J.10
  • 2
    • 11844288876 scopus 로고    scopus 로고
    • A Leishmania major response locus identified by interval-specific congenic mapping of a T helper type 2 cell bias-controlling quantitative trait locus
    • Baguet, A., Epler, J., Wen, K.W. & Bix, M. (2004) A Leishmania major response locus identified by interval-specific congenic mapping of a T helper type 2 cell bias-controlling quantitative trait locus. J. Exp. Med., 200, 1605-1612.
    • (2004) J. Exp. Med , vol.200 , pp. 1605-1612
    • Baguet, A.1    Epler, J.2    Wen, K.W.3    Bix, M.4
  • 3
    • 0021921141 scopus 로고
    • Limbic seizure and brain damage produced by kainic acid: Mechanisms and relevance to human temporal lobe epilepsy
    • Ben-Ari, Y. (1985) Limbic seizure and brain damage produced by kainic acid: mechanisms and relevance to human temporal lobe epilepsy. Neuroscience, 14, 375-403.
    • (1985) Neuroscience , vol.14 , pp. 375-403
    • Ben-Ari, Y.1
  • 4
    • 0034333266 scopus 로고    scopus 로고
    • Kainate, a double agent that generates seizures: Two decades of progress
    • Ben-Ari, Y. & Cossart, R. (2000) Kainate, a double agent that generates seizures: two decades of progress. Trends Neurosci., 23, 580-587.
    • (2000) Trends Neurosci , vol.23 , pp. 580-587
    • Ben-Ari, Y.1    Cossart, R.2
  • 5
    • 0036860323 scopus 로고    scopus 로고
    • Genetic dissection of quantitative trait loci specifying sedative/hypnotic sensitivity to ethanol: Mapping with interval-specific congenic recombinant lines
    • Bennett, B., Beeson, M., Gordon, L., Carosone-Link, P. & Johnson, T.E. (2002) Genetic dissection of quantitative trait loci specifying sedative/hypnotic sensitivity to ethanol: mapping with interval-specific congenic recombinant lines. Alcoholism: Clin. Exp. Res., 26, 1615-1624.
    • (2002) Alcoholism: Clin. Exp. Res , vol.26 , pp. 1615-1624
    • Bennett, B.1    Beeson, M.2    Gordon, L.3    Carosone-Link, P.4    Johnson, T.E.5
  • 6
    • 0023034186 scopus 로고
    • Limbic seizures induced by systemically applied kainic acid: How much kaininic acid reaches the brain?
    • Berger, M. L., Lefauconnier, J. M., Tremblay, E. & Ben-Ari, Y. (1986) Limbic seizures induced by systemically applied kainic acid: how much kaininic acid reaches the brain?. Adv. Exp. Med. Biol., 203, 199-209.
    • (1986) Adv. Exp. Med. Biol , vol.203 , pp. 199-209
    • Berger, M.L.1    Lefauconnier, J.M.2    Tremblay, E.3    Ben-Ari, Y.4
  • 8
    • 0024093449 scopus 로고
    • Glutamate neurotoxicity and diseases of the nervous system
    • Choi, D.W. (1988) Glutamate neurotoxicity and diseases of the nervous system. Neuron, 1, 623-634.
    • (1988) Neuron , vol.1 , pp. 623-634
    • Choi, D.W.1
  • 9
    • 0242291131 scopus 로고    scopus 로고
    • The nature and identification of quantitative trait loci: A community's view
    • Complex Trait Consortium
    • Complex Trait Consortium (2003) The nature and identification of quantitative trait loci: a community's view. Nat. Rev. Genet., 4, 911-916.
    • (2003) Nat. Rev. Genet , vol.4 , pp. 911-916
  • 11
    • 0036862139 scopus 로고    scopus 로고
    • Fine mapping of polymorphic alcohol-related quantitative trait loci candidate genes using interval-specific congenic recombinant mice
    • Ehringer, M.A., Thompson, J., Conroy, O., Yang, F., Hink, R., Bennett, B., Johnson, T.E. & Sikela, J.M. (2002) Fine mapping of polymorphic alcohol-related quantitative trait loci candidate genes using interval-specific congenic recombinant mice. Alcohol Clin. Exp. Res., 26, 1603-1608.
    • (2002) Alcohol Clin. Exp. Res , vol.26 , pp. 1603-1608
    • Ehringer, M.A.1    Thompson, J.2    Conroy, O.3    Yang, F.4    Hink, R.5    Bennett, B.6    Johnson, T.E.7    Sikela, J.M.8
  • 12
    • 0036584950 scopus 로고    scopus 로고
    • Congenic mapping of alcohol and pentobarbital withdrawal liability loci to a <1 centimorgan interval of murine chromosome 4: Identification of Mpdz as a candidate gene
    • Fehr, C., Shirley, R.L., Belknap, J.K., Crabbe, J.C. & Buck, K.J. (2002) Congenic mapping of alcohol and pentobarbital withdrawal liability loci to a <1 centimorgan interval of murine chromosome 4: Identification of Mpdz as a candidate gene. J. Neurosci., 22, 3730-3738.
    • (2002) J. Neurosci , vol.22 , pp. 3730-3738
    • Fehr, C.1    Shirley, R.L.2    Belknap, J.K.3    Crabbe, J.C.4    Buck, K.J.5
  • 13
    • 0028939638 scopus 로고
    • Differential susceptibility to seizures induced by systemic kainic acid treatment in mature DBA/2J and C57BL/6J mice
    • Ferraro, T.N., Golden, G.T., Smith, G.G. & Berrettini, W.H. (1995) Differential susceptibility to seizures induced by systemic kainic acid treatment in mature DBA/2J and C57BL/6J mice. Epilepsia, 36, 301-307.
    • (1995) Epilepsia , vol.36 , pp. 301-307
    • Ferraro, T.N.1    Golden, G.T.2    Smith, G.G.3    Berrettini, W.H.4
  • 15
    • 0024449997 scopus 로고
    • Animal models of the epilepsies
    • Fisher, R.S. (1989) Animal models of the epilepsies. Brain Res. Rev., 14, 245-278.
    • (1989) Brain Res. Rev , vol.14 , pp. 245-278
    • Fisher, R.S.1
  • 16
  • 17
    • 0029042668 scopus 로고
    • Physiologic and morphologic characteristics of granule cell circuitry in human epileptic hippocampus
    • Franck, J.E., Pokorny, J., Kunkel, D.D. & Schwartzkroin, P.A. (1995) Physiologic and morphologic characteristics of granule cell circuitry in human epileptic hippocampus. Epilepsia, 36, 543-558.
    • (1995) Epilepsia , vol.36 , pp. 543-558
    • Franck, J.E.1    Pokorny, J.2    Kunkel, D.D.3    Schwartzkroin, P.A.4
  • 18
    • 0028830749 scopus 로고
    • Neuroprotective effect of ketamine administered after status epilepticus onset
    • Fujikawa, D.G. (1995) Neuroprotective effect of ketamine administered after status epilepticus onset. Epilepsia, 36, 186-195.
    • (1995) Epilepsia , vol.36 , pp. 186-195
    • Fujikawa, D.G.1
  • 19
    • 0030600008 scopus 로고    scopus 로고
    • The temporal evolution of neuronal damage from pilocarpine-induced status epilepticus
    • Fujikawa, D.G. (1996) The temporal evolution of neuronal damage from pilocarpine-induced status epilepticus. Brain Res., 725, 11-22.
    • (1996) Brain Res , vol.725 , pp. 11-22
    • Fujikawa, D.G.1
  • 20
    • 0028214634 scopus 로고
    • The competitive NMDA receptor antagonist CGP 40116 protects against status epilepticus-induced neuronal damage
    • Fujikawa, D.G., Daniels, A.H. & Kim, J.S. (1994) The competitive NMDA receptor antagonist CGP 40116 protects against status epilepticus-induced neuronal damage. Epilepsy Res., 17, 207-219.
    • (1994) Epilepsy Res , vol.17 , pp. 207-219
    • Fujikawa, D.G.1    Daniels, A.H.2    Kim, J.S.3
  • 21
    • 0036949452 scopus 로고    scopus 로고
    • Under what circumstances can seizures produce hippocampal injury: Evidence for age-specific effects
    • Galanopoulou, A.S., Vidaurre, J. & Moshe, S.L. (2002) Under what circumstances can seizures produce hippocampal injury: evidence for age-specific effects. Dev. Neurosci., 24, 355-363.
    • (2002) Dev. Neurosci , vol.24 , pp. 355-363
    • Galanopoulou, A.S.1    Vidaurre, J.2    Moshe, S.L.3
  • 23
    • 0037069250 scopus 로고    scopus 로고
    • Seizure-induced neuronal injury: Animal data
    • Holmes, G.L. (2002) Seizure-induced neuronal injury: animal data. Neurology, 59, S3-S6.
    • (2002) Neurology , vol.59
    • Holmes, G.L.1
  • 24
    • 0032501193 scopus 로고    scopus 로고
    • Neuronal stress and injury in C57/BL mice after systemic kainic acid administration
    • Hu, R.Q., Koh, S., Torgerson, T. & Cole, A.J. (1998) Neuronal stress and injury in C57/BL mice after systemic kainic acid administration. Brain Res., 810, 229-240.
    • (1998) Brain Res , vol.810 , pp. 229-240
    • Hu, R.Q.1    Koh, S.2    Torgerson, T.3    Cole, A.J.4
  • 25
    • 0028090414 scopus 로고
    • Genetic dissection of complex traits
    • Lander, E.S. & Schork, N.J. (1994) Genetic dissection of complex traits. Science, 265, 2037-2048.
    • (1994) Science , vol.265 , pp. 2037-2048
    • Lander, E.S.1    Schork, N.J.2
  • 26
    • 0036348280 scopus 로고    scopus 로고
    • New insights from the use of pilocarpine and kainate models
    • Leite, J.P., Garcia-Cairsaco, N. & Cavalheiro, E.A. (2002) New insights from the use of pilocarpine and kainate models. Epilepsy Res., 50, 93-103.
    • (2002) Epilepsy Res , vol.50 , pp. 93-103
    • Leite, J.P.1    Garcia-Cairsaco, N.2    Cavalheiro, E.A.3
  • 27
    • 0030659604 scopus 로고    scopus 로고
    • Theoretical and empirical issues for marker-assisted breeding of congenic mouse strains
    • Markel, P., Shu, P., Ebeling, C., Carlson, G.A., Nagle, D.L., Smutko, J.S. & Moore, K.J. (1997) Theoretical and empirical issues for marker-assisted breeding of congenic mouse strains. Nat. Genet., 17, 280-284.
    • (1997) Nat. Genet , vol.17 , pp. 280-284
    • Markel, P.1    Shu, P.2    Ebeling, C.3    Carlson, G.A.4    Nagle, D.L.5    Smutko, J.S.6    Moore, K.J.7
  • 28
    • 0031971459 scopus 로고    scopus 로고
    • Anoxia during kainate status epilepticus shortens behavioral convulsions but generates hippocampal neuron loss and supragranular mossy fiber sprouting
    • Mathern, G.W., Price, G., Rosales, C., Pretorius, J.K., Lozada, A. & Mendoza, D. (1998) Anoxia during kainate status epilepticus shortens behavioral convulsions but generates hippocampal neuron loss and supragranular mossy fiber sprouting. Epilepsy Res., 30, 133-151.
    • (1998) Epilepsy Res , vol.30 , pp. 133-151
    • Mathern, G.W.1    Price, G.2    Rosales, C.3    Pretorius, J.K.4    Lozada, A.5    Mendoza, D.6
  • 29
    • 0036456829 scopus 로고    scopus 로고
    • Hippocampal neuron damage in human epilepsy: Meyer's hypothesis revisited
    • Mathern, G.W., Adelson, P.D., Cahan, L.D. & Leite, J.P. (2002) Hippocampal neuron damage in human epilepsy: Meyer's hypothesis revisited. Prog. Brain Res., 135, 237-251.
    • (2002) Prog. Brain Res , vol.135 , pp. 237-251
    • Mathern, G.W.1    Adelson, P.D.2    Cahan, L.D.3    Leite, J.P.4
  • 30
    • 20444413825 scopus 로고    scopus 로고
    • Regulation of limbic status epilepticus by hippocampal galanin type 1 and type 2 receptors
    • Mazarati, A. & Lu, X. (2005) Regulation of limbic status epilepticus by hippocampal galanin type 1 and type 2 receptors. Neuropeptides, 39, 277-280.
    • (2005) Neuropeptides , vol.39 , pp. 277-280
    • Mazarati, A.1    Lu, X.2
  • 32
    • 4444310169 scopus 로고    scopus 로고
    • Patterns of seizures, hippocampal injury and neurogenesis in three models of status epilepticus in galanin receptor type 1 (Galr1) knockout mice
    • Mazarati, A., Lu, X., Shinmei, S., Badie-Mahdavi, H. & Bartfai, T. (2004) Patterns of seizures, hippocampal injury and neurogenesis in three models of status epilepticus in galanin receptor type 1 (Galr1) knockout mice. Neuroscience, 128, 431-441.
    • (2004) Neuroscience , vol.128 , pp. 431-441
    • Mazarati, A.1    Lu, X.2    Shinmei, S.3    Badie-Mahdavi, H.4    Bartfai, T.5
  • 33
    • 0024284028 scopus 로고
    • A simple salting out procedure for extracting DNA from human nucleated cells
    • Miller, S.A., Dykes, D.D. & Polesky, H.F. (1988) A simple salting out procedure for extracting DNA from human nucleated cells. Nucl. Acids Res., 16, 1215.
    • (1988) Nucl. Acids Res , vol.16 , pp. 1215
    • Miller, S.A.1    Dykes, D.D.2    Polesky, H.F.3
  • 35
    • 0020973516 scopus 로고
    • Use of excitatory amino acids to make axon-sparing lesions of hypothalamus
    • Nadler, J.V. & Evenson, D.A. (1983) Use of excitatory amino acids to make axon-sparing lesions of hypothalamus. Meth. Enzymol., 103, 393-400.
    • (1983) Meth. Enzymol , vol.103 , pp. 393-400
    • Nadler, J.V.1    Evenson, D.A.2
  • 36
    • 0024399770 scopus 로고
    • Excitatory amino acids and neuropsychiatric disorders
    • Olney, J.W. (1989) Excitatory amino acids and neuropsychiatric disorders. Biol. Psychiat., 26, 505-525.
    • (1989) Biol. Psychiat , vol.26 , pp. 505-525
    • Olney, J.W.1
  • 37
    • 0022566936 scopus 로고
    • Excitotoxic mechanisms of epileptic brain damage
    • Olney, J.W., Collins, R.C. & Sloviter, R.S. (1986) Excitotoxic mechanisms of epileptic brain damage. Adv. Neurol., 44, 857-877.
    • (1986) Adv. Neurol , vol.44 , pp. 857-877
    • Olney, J.W.1    Collins, R.C.2    Sloviter, R.S.3
  • 38
    • 0015309163 scopus 로고
    • Modification of seizure activity electrical stimulation. II. Motor seizure
    • Racine, R.J. (1972) Modification of seizure activity electrical stimulation. II. Motor seizure. Electroencephalogr. Clin. Neurophysiol., 32, 281-294.
    • (1972) Electroencephalogr. Clin. Neurophysiol , vol.32 , pp. 281-294
    • Racine, R.J.1
  • 39
    • 0043073123 scopus 로고    scopus 로고
    • Protection provided by cyclosporin A against excitotoxic neuronal death is genotype dependent
    • Santos, J.B. & Schauwecker, P.E. (2003) Protection provided by cyclosporin A against excitotoxic neuronal death is genotype dependent. Epilepsia, 44, 995-1002.
    • (2003) Epilepsia , vol.44 , pp. 995-1002
    • Santos, J.B.1    Schauwecker, P.E.2
  • 40
    • 0034711544 scopus 로고    scopus 로고
    • Seizure-induced neuronal death is associated with induction of c-Jun N-terminal kinase and is dependent on genetic background
    • Schauwecker, P.E. (2000) Seizure-induced neuronal death is associated with induction of c-Jun N-terminal kinase and is dependent on genetic background. Brain Res., 884, 116-128.
    • (2000) Brain Res , vol.884 , pp. 116-128
    • Schauwecker, P.E.1
  • 41
    • 0036454473 scopus 로고    scopus 로고
    • Complications associated with genetic background effects in models of experimental epilepsy
    • Schauwecker, P.E. (2002a) Complications associated with genetic background effects in models of experimental epilepsy. Prog. Brain Res., 135, 139-148.
    • (2002) Prog. Brain Res , vol.135 , pp. 139-148
    • Schauwecker, P.E.1
  • 42
    • 0036939162 scopus 로고    scopus 로고
    • Modulation of cell death by mouse genotype: Differential vulnerability to excitatory amino acid-induced lesions
    • Schauwecker, P.E. (2002b) Modulation of cell death by mouse genotype: differential vulnerability to excitatory amino acid-induced lesions. Exp. Neurol., 178, 219-235.
    • (2002) Exp. Neurol , vol.178 , pp. 219-235
    • Schauwecker, P.E.1
  • 43
    • 0037430932 scopus 로고    scopus 로고
    • Differences in ionotropic glutamate receptor subunit expression are not responsible for strain-dependent susceptibility to excitotoxin-induced injury
    • Schauwecker, P.E. (2003a) Differences in ionotropic glutamate receptor subunit expression are not responsible for strain-dependent susceptibility to excitotoxin-induced injury. Mol. Brain Res., 112, 70-81.
    • (2003) Mol. Brain Res , vol.112 , pp. 70-81
    • Schauwecker, P.E.1
  • 44
    • 0041324719 scopus 로고    scopus 로고
    • Genetic basis of kainate-induced excitotoxicity in mice: Phenotypic modulation of seizure-induced cell death
    • Schauwecker, P.E. (2003b) Genetic basis of kainate-induced excitotoxicity in mice: phenotypic modulation of seizure-induced cell death. Epilepsy Res., 55, 201-210.
    • (2003) Epilepsy Res , vol.55 , pp. 201-210
    • Schauwecker, P.E.1
  • 45
    • 0030887853 scopus 로고    scopus 로고
    • Genetic determinants of susceptibility to excitotoxic cell death: Implications for gene targeting approaches
    • Schauwecker, P.E. & Steward, O. (1997) Genetic determinants of susceptibility to excitotoxic cell death: implications for gene targeting approaches. Proc. Natl Acad. Sci. U.S.A., 94, 4103-4108.
    • (1997) Proc. Natl Acad. Sci. U.S.A , vol.94 , pp. 4103-4108
    • Schauwecker, P.E.1    Steward, O.2
  • 46
    • 0034010127 scopus 로고    scopus 로고
    • Genetic dissection of the signals that induce synaptic reorganization
    • Schauwecker, P.E., Ramirez, J.J. & Steward, O. (2000) Genetic dissection of the signals that induce synaptic reorganization. Exp. Neurol., 161, 139-152.
    • (2000) Exp. Neurol , vol.161 , pp. 139-152
    • Schauwecker, P.E.1    Ramirez, J.J.2    Steward, O.3
  • 47
    • 3843081736 scopus 로고    scopus 로고
    • Genetic control of sensitivity to hippocampal cell death induced by kainic acid: A quantitative trait loci analysis
    • Schauwecker, P.E., Williams, R.W. & Santos, J.B. (2004) Genetic control of sensitivity to hippocampal cell death induced by kainic acid: a quantitative trait loci analysis. J. Comp. Neurol., 477, 96-107.
    • (2004) J. Comp. Neurol , vol.477 , pp. 96-107
    • Schauwecker, P.E.1    Williams, R.W.2    Santos, J.B.3
  • 48
    • 13844253258 scopus 로고    scopus 로고
    • Fluoro-Jade C results in ultra high resolution and contrast labeling of degenerating neurons
    • Schmued, L.C., Stowers, C.C., Scallet, A.C. & Xu, L. (2005) Fluoro-Jade C results in ultra high resolution and contrast labeling of degenerating neurons. Brain Res., 1035, 24-31.
    • (2005) Brain Res , vol.1035 , pp. 24-31
    • Schmued, L.C.1    Stowers, C.C.2    Scallet, A.C.3    Xu, L.4
  • 49
    • 0028057773 scopus 로고
    • Kainic acid seizures in the rat
    • Sperk, G. (1994) Kainic acid seizures in the rat. Prog. Neurobiol., 42, 1-32.
    • (1994) Prog. Neurobiol , vol.42 , pp. 1-32
    • Sperk, G.1
  • 51
    • 84886639406 scopus 로고
    • Kainic acid-induced seizures: Dose-relationship of behavioural, neurochemical and histopathological changes
    • Sperk, G., Lassmann, H., Baran, H., Seitelberger, F. & Hornykiewicz, O. (1985) Kainic acid-induced seizures: dose-relationship of behavioural, neurochemical and histopathological changes. Brain Res., 338, 289-295.
    • (1985) Brain Res , vol.338 , pp. 289-295
    • Sperk, G.1    Lassmann, H.2    Baran, H.3    Seitelberger, F.4    Hornykiewicz, O.5
  • 52
    • 33646712589 scopus 로고    scopus 로고
    • Treatment of experimental status epilepticus in immaturerats: Dissociation between anticonvulsant and antiepileptogenic effects
    • Suchomelova, L., Baldwin, R. A., Kuvoba, H., Thompson, K. W., Sankar, R. & Wasterlain, C. G. (2006) Treatment of experimental status epilepticus in immaturerats: dissociation between anticonvulsant and antiepileptogenic effects. Pediatr. Res., 59, 237-243.
    • (2006) Pediatr. Res , vol.59 , pp. 237-243
    • Suchomelova, L.1    Baldwin, R.A.2    Kuvoba, H.3    Thompson, K.W.4    Sankar, R.5    Wasterlain, C.G.6
  • 53
    • 0020545095 scopus 로고
    • Limbic seizures produced by pilocarpine in rats: Behavioural, electroencephalographic and neuropathological study
    • Turski, W.A., Cavalheiro, E.A., Schwarz, M., Czuczwar, S.J., Kleinrok, Z. & Turski, L. (1983) Limbic seizures produced by pilocarpine in rats: behavioural, electroencephalographic and neuropathological study. Behav. Brain Res., 9, 315-335.
    • (1983) Behav. Brain Res , vol.9 , pp. 315-335
    • Turski, W.A.1    Cavalheiro, E.A.2    Schwarz, M.3    Czuczwar, S.J.4    Kleinrok, Z.5    Turski, L.6
  • 54
    • 0023478437 scopus 로고
    • The seizures induced by pilocarpine: Behavioral, electroencephalographic and neuropathological studies in rodents
    • Turski, L., Cavalheiro, E.A., Czuczwar, S.J., Turski, W.A. & Kleinrok, Z. (1987) The seizures induced by pilocarpine: behavioral, electroencephalographic and neuropathological studies in rodents. Pol. J. Pharmacol. Pharm., 39, 545-555.
    • (1987) Pol. J. Pharmacol. Pharm , vol.39 , pp. 545-555
    • Turski, L.1    Cavalheiro, E.A.2    Czuczwar, S.J.3    Turski, W.A.4    Kleinrok, Z.5
  • 55
    • 0030959717 scopus 로고    scopus 로고
    • Speed congenics: A classic technique in the fast lane (relatively speaking)
    • Wakeland, E., Morel, L., Achey, K., Yui, M. & Longmate, J. (1997) Speed congenics: a classic technique in the fast lane (relatively speaking). Immunol. Today, 18, 472-477.
    • (1997) Immunol. Today , vol.18 , pp. 472-477
    • Wakeland, E.1    Morel, L.2    Achey, K.3    Yui, M.4    Longmate, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.