CD83 is a regular of murine B cell function in vivo

European Journal of Immunology

Volumn 37, Issue 3, 2007, Pages 634-648

  Breloer, Minka ^a   Kretschmer, Birte ^a   Lüthje, Katja ^a   Ehrlich, Svenja ^a   Ritter, Uwe ^a   Bickert, Thomas ^a   Steeg, Christiane ^a   Fillatreau, Simon ^b   Hoehlig, Kai ^b   Lampropoulou, Vassiliki ^b   Fleischer, Bernhard ^a,c  

^a BERNHARD NOCHT INSTITUTE FOR TROPICAL MEDICINE   (Germany)

^b DEUTSCHES RHEUMA FORSCHUNGSZENTRUM   (Germany)

^c UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Antibody response; B cell activation; Transgenic mice

Indexed keywords

BIOCHEMICAL MARKER; CD83 ANTIGEN; GLYCOPROTEIN; IMMUNOGLOBULIN; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; T LYMPHOCYTE ANTIBODY; LEUKOCYTE ANTIGEN; MEMBRANE PROTEIN; PROTOZOON ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ANTIGEN EXPRESSION; ANTIGEN SPECIFICITY; ARTICLE; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; BONE MARROW; CELL MATURATION; CONTROLLED STUDY; DENDRITIC CELL; FEMALE; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOREGULATION; IN VIVO STUDY; LEISHMANIA MAJOR; LEISHMANIASIS; LYMPHATIC DRAINAGE; LYMPHOCYTE FUNCTION; LYMPHOCYTE SUBPOPULATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; THYMUS; UPREGULATION; WILD TYPE; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; C57BL MOUSE; GENETICS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; PHYSIOLOGY; SKIN LEISHMANIASIS; TRANSGENIC MOUSE;

ANIMALS; ANTIBODIES, PROTOZOAN; ANTIGENS, CD; B-LYMPHOCYTES; FEMALE; IMMUNOGLOBULINS; LEISHMANIA MAJOR; LEISHMANIASIS, CUTANEOUS; LYMPHOCYTE ACTIVATION; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, TRANSGENIC; UP-REGULATION;

EID: 34147182126     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200636852     Document Type: Article

References (38)

1. Zhou, L. J., Schwarting, R., Smith, H. M. and Tedder, T. F., A novel cell-surface molecule expressed by human interdigitating reticulum cells, Langerhans cells, and activated lymphocytes is a new member of the Ig superfamily. J. Immunol. 1992. 149: 735-742.
2. Kozlow, E. J., Wilson, G. L., Fox, C. H. and Kehrl, J. H., Subtractive cDNA cloning of a novel member of the Ig gene superfamily expressed at high levels in activated B lymphocytes. Blood 1993. 81: 454-461.
3. + dendritic cells. Proc. Natl. Acad. Sci. USA 1996. 93: 2588-2592.
4. Zhou, L. J. and Tedder, T. F., Human blood dendritic cells selectively express CD83, a member of the immunoglobulin superfamily. J. Immunol. 1995. 154: 3821-3835.
5. Twist, C. J., Beier, D. R., Disteche, C. M., Edelhoff, S. and Tedder, T. F., The mouse U83 gene: Structure, domain organization, and chromosome localization. Immunogenetics 1998. 48: 383-393.
6. Berchtold, S., Muhl-Zurbes, P., Heufler, C., Winklehner, P., Schuler, G. and Steinkasserer, A., Cloning, recombinant expression and biochemical characterization of the routine CD83 molecule which is specifically upregulated during dendritic cell maturation. FEBS Lett. 1999. 461: 211-216.
7. Wolenski, M., Cramer, S. O., Ehrlich, S., Steeg, C., Grossschupff, G., Tenner-Racz, K., Racz, P. et al., Expression of CD83 in the routine immune system. Med. Microbial. Immunol. (Berl.) 2003. 192: 189-192.
8. + T cell development in the thymus. Cell 2002. 108: 755-767.
9. + cells. J. Immunol. 2004. 173: 2995-3001.
10. Luthje, K., Cramer, S. O., Ehrlich, S., Veit, A., Steeg, C., Fleischer, B., Bonin, A. V. and Breloer, M., Transgenic expression of a CD83-immunoglobulin fusion protein impairs the development of immune-competent CD4-positive T cells. Eur. J. Immunol. 2006. 36: 2035-2045.
11. Lechmann, M., Berchtold, S., Hauber, J. and Steinkasserer, A., CD83 on dendritic cells: More than just a marker for maturation. Trends Immunol. 2002. 23: 273-275.
12. Cramer, S. O., Trumpfheller, C., Mehlhoop, U., More, S., Fleischer, B. and von Bonin, A., Activation-induced expression ofmurine CD83 on T cells and identification of a specific CD83 ligand on murine B cells. Int. Immunol. 2000. 12: 1347-1351.
13. Lechmann, M., Krooshoop, D. J., Dudziak, D., Kremmer, E., Kuhnt, C., Figdor, C. G., Schuler, G. and Steinkasserer, A., The extracellular domain of CD83 inhibits dendritic cell-mediated T cell stimulation and binds to a ligand on dendritic cells. J. Exp. Med. 2001. 194: 1813-1821.
14. Dudziak, D., Nimmerjahn, F., Bornkamm, G. W. and Laux, G., Alternative splicing generates putative soluble CD83 proteins that inhibit T cell proliferation. J. Immunol. 2005. 174: 6672-6676.
15. Scholler, N., Hayden-Ledbetter, M., Dahlin, A., Hellstrom, L, Hellstrom, K. E. and Ledbetter, J. A., Cutting edge: CD83 regulates the development of cellular immunity. J. Immunol. 2002. 168: 2599-2602.
16. Yang, S., Yang, Y., Raycraft, J., Zhang, H., Kanan, S., Guo, Y., Ronai, Z. et al., Melanoma cells transfected to express CD83 induce antitumor immunity that can be increased by also engaging CD137. Proc. Natl. Acad. Sci. USA 2004. 101: 4990-4995.
17. Zinser, E., Lechmann, M., Golka, A., Lutz, M. B. and Steinkasserer, A., Prevention and treatment of experimental autoimmune encephalomyelitis by soluble CD83. J. Exp. Med. 2004. 200: 345-351.
18. Senechal, B., Boruchov, A. M., Reagan, J. L., Hart, D. N. and Young, J. W., Infection of mature monocyte-derived dendritic cells with human cytomegalovirus inhibits stimulation of T-cell proliferation via the release of soluble CD83. Blood 2004. 103: 4207-4215.
19. + T cells and preferential enrichment for antigen specificity. Blood 2006. 107: 1528-1536.
20. Sharpe, A. H. and Freeman, G. J., The B7-CD28 superfamily. Nat. Rev. Immunol. 2002. 2: 116-126.
21. Wolenski, M., Cramer, S. O., Ehrlich, S., Steeg, C., Fleischer, B. and von Bonin, A., Enhanced activation of CD83-positive T cells. Scand. J. Immunol. 2003. 58: 306-311.
22. Sacks, D. and Noben-Trauth, N., The immunology of susceptibility and resistance to Leishmania major in mice. Nat. Rev. Immunol. 2002. 2: 845-858.
23. Alexander, J. and Bryson, K., T helper (h)1/Th2 and Leishmania: Paradox rather than paradigm. Immunol. Lett. 2005. 99: 17-23.
24. Mond, J. J., Lees, A. and Snapper, C. M., T cell-independent antigens type 2. Annu. Rev. Immunol. 1995. 13: 655-692.
25. Brown, D. R. and Reiner, S. L., Polarized helper-T-cell responses against Leishmania major in the absence of B cells. Infect. Immun. 1999. 67: 266-270.
26. DosReis, G. A., Cell-mediated immunity in experimental Trypanosoma cruzi infection. Parasitol. Today 1997. 13: 335-342.
27. Tarleton, R. L., Grusby, M. J., Postan, M. and Glimcher, L. H., Trypanosoma cruzi infection in MHC-deficient mice: Further evidence for the role of both class I- and class II-restricted T cells in immune resistance and disease. Int. Immunol. 1996. 8: 13-22.
28. + T cell function to immune control of Trypanosoma cruzi. Parasite Immunol. 1998. 20: 207-216.
29. Hock, B. D., Kato, M., McKenzie, J. L. and Hart, D. N., A soluble form of CD83 is released from activated dendritic cells and B lymphocytes, and is detectable in normal human sera. Int. Immunol. 2001. 13: 959-967
30. Pasare, C. and Medzhitov, R., Control of B-cell responses by Toll-like receptors. Nature 2005. 438: 364-368.
31. Nemazee, D., Gavin, A., Hoebe, K. and Beutler, B., Immunology: Toll-like receptors and antibody responses. Nature 2006. 441: E4.
32. Fujimoto, Y. and Tedder, T. F., CD83: A regulatory molecule of the immune system with great potential for therapeutic application. J. Med. Dent. Sci. 2006. 53: 85-91.
33. + T cells. J. Immunol. 2001. 166: 3865-3872.
34. Niiro, H. and Clark, E. A., Regulation of B-cell fate by antigen-receptor signals. Nat. Rev. Immunol. 2002. 2: 945-956.
35. Nitschke, L., Carsetti, R., Ocker, B., Kohler, G. and Lamers, M. C., CD22 is a negative regulator of B-cell receptor signalling. Curr. Biol. 1997. 7: 133-143.
36. Pan, C., Baumgarth, N. and Parnes, J. R., CD72-deficient mice reveal nonredundant roles of CD72 in B cell development and activation. Immunity 1999. 11: 495-506.
37. Crocker, P. R. and Varki, A., Siglecs in the immune system. Immunology 2001. 103: 137-145.
38. Ritter, U., Mattner, J., Rocha, J. S., Bogdan, C. and Korner, H., The control of Leishmania (Leishmania) major by TNF in vivo is dependent on the parasite strain. Microbes Infect. 2004. 6: 559-565.