Differential histone H3 lys-9 and lys-27 methylation profiles on the X chromosome

Molecular and Cellular Biology

Volumn 24, Issue 12, 2004, Pages 5475-5484

  Rougeulle, Claire ^a,e   Chaumeil, Julie ^b   Sarma, Kavitha ^c   Allis, C David ^d   Reinberg, Danny ^c   Avner, Philip ^a   Heard, Edith ^b,e  

^a INSTITUT PASTEUR   (France)

^b INSTITUT CURIE   (France)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d ROCKEFELLER UNIVERSITY   (United States)

^e CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE H3; HISTONE METHYLTRANSFERASE; LYSINE; METHYLTRANSFERASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHROMATIN; CHROMOSOME INACTIVATION; EMBRYO; FEMALE; KINETICS; MALE; METHYLATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN MODIFICATION; STEM CELL; X CHROMOSOME;

ANIMALS; CELLS, CULTURED; DOSAGE COMPENSATION, GENETIC; FEMALE; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; KINETICS; LYSINE; MALE; METHYLATION; MICE; MUTATION; RNA, UNTRANSLATED; X CHROMOSOME;

ANIMALIA;

EID: 2342505217     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.24.12.5475-5484.2004     Document Type: Article

References (36)

1. Boggs, B. A., P. Cheung, E. Heard, D. L. Spector, A. C. Chinault, and C. D. Allis. 2002. Differentially methylated forms of histone H3 show unique association patterns with inactive human X chromosomes. Nat. Genet. 30:73-76.
2. Boggs, B. A., B. Connors, R. E. Sobel, A. C. Chinault, and C. D. Allis. 1996. Reduced levels of histone H3 acetylation on the inactive X chromosome in human females. Chromosoma 105:303-309.
3. Brown, C. J., B. D. Hendrich, J. L. Rupert, R. G. Lafrenière, Y. Xing, R. G. Lawrence, and H. F. Willard. 1992. The human XIST gene: analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus. Cell 71:527-542.
4. Chaumeil, J., I. Okamoto, M. Guggiari, and E. Heard. 2002. Integrated kinetics of X chromosome inactivation in differentiating embryonic stem cells. Cytogenet. Cell Genet. 99:75-84.
5. Clemson, C. M., J. A. Mc Neil, H. F. Willard, and J. B. Lawrence. 1996. XIST RNA paints the inactive X chromosome at interphase: evidence for a novel RNA involved in nuclear/chromosome structure. J. Cell Biol. 132:259-275.
6. Costanzi, C., P. Stein, D. M. Worrad, R. M. Schultz, and J. R. Pehrson. 2000. Histone macroH2A1 is concentrated in the inactive X chromosome of female preimplantation mouse embryos. Development 127:2283-2289.
7. Czermin, B., R. Melfi, D. McCabe, V. Seitz, A. Imhof, and V. Pirrotta. 2002. Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyl-transferase activity that marks chromosomal Polycomb sites. Cell 111:85-96.
8. Fischle, W., Y. Wang, S. A. Jacobs, Y. Kim, C. D. Allis, and S. Khorasanizadeh. 2003. Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 bt Polycomb and HP1 chromodomains. Genes Dev. 17:1870-1881.
9. Heard, E., C. Rougeulle, D. Arnaud, P. Avner, C. D. Allis, and D. L. Spector. 2001. Methylation of histone H3 at Lys-9 is an early mark on the X chromosome during X inactivation. Cell 107:727-738.
10. Hogan, B., R. Beddington, F. Constantini, and E. Lacy. 1994. Manipulating the mouse embryo: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
11. Jeppesen, P., and B. M. Turner. 1993. The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenetic marker for gene expression. Cell 74:281-289.
12. Keohane, A. M., L. P. O'Neil, N. D. Belyaev, J. S. Lavender, and B. M. Turner. 1996. X inactivation and histone H4 acetylation in embryonic stem cells. Dev. Biol. 180:618-630.
13. Kuzmichev, A., K. Nishioka, H. Erdjument-Bromage, P. Tempst, and D. Reinberg. 2002. Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein. Genes Dev. 16:2893-2905.
14. Lyon, M. F. 1961. Gene action in the X chromosome of the mouse (Mus musculus L.). Nature 190:372-373.
15. Mak, W., J. Baxter, J. Silva, A. E. Newall, A. P. Otte, and N. Brockdorff. 2002. Mitotically stable association of polycomb group proteins Eed and Enx1 with the inactive X chromosome in trophoblast stem cells. Curr. Biol. 12:1016-1020.
16. Mak, W., T. B. Nesterova, M. de Napoles, R. Appanah, S. Yamanaka, A. P. Otte, and N. Brockdorff. 2004. Reactivation of the paternal X chromosome in early mouse embryos. Science 303:666-669.
17. Mermoud, J. E., B. Popova, A. H. Peters, T. Jenuwein, and N. Brockdorff. 2002. Histone H3 lysine 9 methylation occurs rapidly at the onset of random X chromosome inactivation. Curr. Biol. 12:247-251.
18. Norris, D. P., N. H. Brockdorff, and S. Rastan. 1991. Methylation status of CpG-rich bands on active and inactive mouse X chromosomes. Mamm. Genome 1:78-83.
19. Okamoto, I., A. P. Otte, C. D. Allis, D. Reinberg, and E. Heard. 2004. Epigenetic dynamics of imprinted X inactivation during early mouse development. Science 303:644-649.
20. Panning, B., J. Dausman, and R. Jaenisch. 1997. X chromosome inactivation is mediated by Xist RNA stabilization. Cell 90:907-916.
21. Peters, A. H., S. Kubicek, K. Mechtler, R. J. O'Sullivan, A. A. Derijck, L. Perez-Burgos, A. Kohlmaier, S. Opravil, M. Tachibana, Y. Shinkai, J. H. Martens, and T. Jenuwein. 2003. Partitioning and plasticity of repressive histone methylation states in mammalian chromatin. Mol. Cell 12:1577-1589.
22. Plath, K., J. Fang, S. K. Mlynarczyk-Evans, R. Cao, K. A. Worringer, H. Wang, C. C. de la Cruz, A. P. Otte, B. Panning, and Y. Zhang. 2003. Role of histone H3 lysine 27 methylation in X inactivation. Science 300:131-135.
23. Rastan, S., and E. J. Robertson. 1985. X-chromosome deletions in embryo-derived (EK) cell lines associated with lack of X-chromosome inactivation. J. Embryol. Exp. Morph. 90:379-388.
24. Rice, J. C., S. D. Briggs, B. Ueberheide, C. M. Barber, J. Shabanowitz, D. F. Hunt, Y. Shinkai, and C. D. Allis. 2003. Histone methyltransferases direct different degrees of methylation to define distinct chromatin domains. Mol. Cell 12:1591-1598.
25. Sarma, K., K. Nishioka, and D. Reinberg. 2004. Tips in analyzing antibodies directed against specific histone tail modifications. Methods Enzymol. 376:255-269.
26. Sheardown, S. A., S. M. Duthie, C. M. Johnston, A. E. Newall, E. J. Formstone, R. M. Arkell, T. B. Nesterova, G. C. Alghisi, S. Rastan, and N. Brockdorff. 1997. Stabilization of Xist RNA mediates initiation of X chromosome inactivation. Cell 91:99-107.
27. Silva, J., W. Mak, I. Zvetkova, R. Appanah, T. B. Nesterova, Z. Webster, A. H. Peters, T. Jenuwein, A. P. Otte, and N. Brockdorff. 2003. Establishment of histone H3 methylation on the inactive X chromosome requires transient recruitment of Eed-Enx1 polycomb group complex. Dev. Cell 4:481-495.
28. Smith, A. G. 1991. Culture and differentiation of embryonic stem cells. J. Tiss. Cult. Methods 13:89-94.
29. Strahl, B. D., and D. C. Allis. 2000. The language of covalent histone modifications. Nature 403:41-45.
30. Tachibana, M., K. Sugimoto, T. Fukushima, and Y. Shinkai. 2001. Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3. J. Biol. Chem. 276:25309-25317.
31. Tachibana, M., K. Sugimoto, M. Nozaki, J. Ueda, T. Ohta, M. Ohki, M. Fukuda, N. Takeda, H. Niida, H. Kato, and Y. Shinkai. 2002. G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis. Genes Dev. 16:1779-1791.
32. Takagi, N., and M. Sasaki. 1975. Preferential inactivation of the paternally derived X chromosome in the extraembryonic membranes of the mouse. Nature 256:640-642.
33. Takagi, N., O. Sugawara, and M. Sasaki. 1982. Regional and temporal changes in the pattern of X-chromosome replication during the early post-implantation development of the female mouse. Chromosoma 85:275-286.
34. Wang, J., J. Mager, Y. Chen, E. Schneider, J. C. Cross, A. Nagy, and T. Magnuson. 2001. Imprinted X inactivation maintained by a mouse Polycomb group gene. Nat. Genet. 28:371-375.
35. Wutz, A., and R. Jaenisch. 2000. A shift from reversible to irreversible X inactivation is triggered during ES cell differentiation. Mol. Cell 5:695-705.
36. Xin, Z., M. Tachibana, M. Guggiari, E. Heard, Y. Shinkai, and J. Wagstaff. 2003. Role of histone methyltransferase G9a in CpG methylation of the Prader-Willi syndrome imprinting center. J. Biol. Chem. 278:14996-15000.