Interaction of the protein C activation peptide with platelets

Preparative Biochemistry and Biotechnology

Volumn 37, Issue 2, 2007, Pages 139-147

  Martínez Cruz, Ruth ^a   Canseco, María Del S Pina ^a   Lopez Martínez, Jael ^a   Cruz, Pedro A Hernández ^a   Pérez Campos, Eduardo ^a,b,f   Cruz, Margarito Martínez ^b   Alva, Félix Córdoba ^b   Majluf Cruz, Abraham ^c   Zenteno, Edgar ^d   Ruiz Argüelles, Alejandro ^e  

^a UNIVERSIDAD AUTÓNOMA BENITO JUÁREZ DE OAXACA   (Mexico)

^b Instituto Tecnologico de   (Mexico)

^c INSTITUTO MEXICANO DEL SEGURO SOCIAL   (Mexico)

^d UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^e Laboratorios Clinicos de Puebla   (Mexico)

^f NONE   (Mexico)

Author keywords

Docking; Peptide; Platelet inhibition; Thrombin

Indexed keywords

ANTITHROMBOCYTIC AGENT; CALCIUM; CELL SURFACE RECEPTOR; ENZYME PRECURSOR; OLIGOPEPTIDE; PROTEIN C ACTIVATOR PEPTIDE; THROMBIN; THROMBIN RECEPTOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CHEMISTRY; DRUG EFFECT; METABOLISM; MOLECULAR GENETICS; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION;

AMINO ACID SEQUENCE; BLOOD PLATELETS; CALCIUM; ENZYME PRECURSORS; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; PLATELET ACTIVATION; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; RECEPTORS, CELL SURFACE; RECEPTORS, THROMBIN; THROMBIN;

EID: 34147131226     PISSN: 10826068     EISSN: 15322297     Source Type: Journal    
DOI: 10.1080/10826060701199072     Document Type: Article

References (21)

1. Heeb, M.J.; Schwarz, H.P.; White, T.; Lammle, B.; Berrettini, M.; Griffin, J.H. Immunoblotting studies of the molecular forms of protein C in plasma. Thromb. Res. 1988, 52, 33-43.
2. Stenflo, J.; Fernlund, P. Amino acid sequence of the heavy chain of bovine protein C. J. Biol. Chem. 1982, 257, 12180-12190.
3. Öhlin, K.A.; Stenflo, J. Calcium-dependent interaction between the epidermal growth factor precursor-like region of human protein C and a monoclonal antibody. J. Biol. Chem. 1987, 262, 13798-13804.
4. Foster, D.C.; Yoshitake, S.; Davie, E.W. The nucleotide sequence of the gene for human protein C. Proc. Natl. Acad. Sci. USA 1985, 82, 4673-4677.
5. Coughlin, S.R. Thrombin signalling and protease-activated receptors. Nature 2000, 407, 258-264.
6. Ramakrishnan, V.; DeGuzman, F.; Bao, M.; Hall, S.W.; Leung, L.L.; Phillips, D.R. A thrombin receptor function for platelet glycoprotein Ib-IX unmasked by cleavage of glycoprotein V. Proc. Natl. Acad. Sci. USA 2001, 98, 1823-1828.
7. Grand, A.R.J.; Turnell, S.A.; Grabham, W.P. Cellular consequences of thrombinreceptor activation. Biochem. J. 1995, 313, 353-368.
8. Shuman, A.M.; Majerus, W.P. The perturbation of thrombin binding to human platelets by anions. J. Clin. Invest. 1975, 56, 945-950.
9. Grynkiewicz, G.; Poenie, M.; Tsien, Y.R. A new generation of Ca2+ indicators with greatly improved fluorescence properties. J. Biol. Chem. 1985, 260, 3440-3450.
10. Merrit, J.E.; McCarthy, S.A.; Davies, M.P.; Moores, K.E. Use of fluo-3 to measure cytosolic Ca2+ in platelet and neutrophils. Biochem. J. 1990, 269, 513-519.
11. Berman, M.H.; Westbrook, J.; Feng, Z.; Gilliland, G.; Bhat, N.T.; Weissig, H.; Shindyalov, N.I.; Bourne, E.P. The Protein Data Bank. Nucleic Acids Res. 2000, 28, 235-242.
12. Santos, B.F.; Serrano, S.M.; Kuliopulos, A.; Niewiarowski, S. Interaction of viper venom serine peptidases with thrombin receptors on human platelets. FEBS Lett. 2000, 477, 199-202.
13. Grand, J.A.R.; Turnell, S.A.; Grabham, W.P. Cellular consequences of thrombin/ receptor activation. J. Biochem. 1995, 313, 353-368.
14. Macfarlane, R.S.; Seatter, J.M.; Kanke, T.; Hunter, D.G.; Plevin, R. Proteinase-activated receptor. Pharmacol. Rev. 2001, 53, 245-282.
15. Hollenberg, D.M.; Compton, J.S. International union of pharmacology. XXVIII. Proteinase-activated receptors. Pharmacol. Rev. 2002, 54, 203-217.
16. Brass, F.L. Thrombin and platelet activation. CHEST. 2003, 124, 18S-25S.
17. Jacques, S.L.; LeMasurier, M.; Sheridan, P.J.; Seeley, S.K.; Kuliopulos, A. Substrate-assisted catalysis of the PAR1 thrombin receptor. J. Biol. Chem. 2000, 275, 40671-40678.
18. Di Cera, E.; Dang, Q.D.; Ayala, Y.M. Molecular mechanism of thrombin function. Cell Mol. Life Sci. 1997, 53, 701-730.
19. Bernatowicz, M.S.; Klimas, C.E.; Hartl, K.S.; Peluso, M.; Allegretto, N.J.; Seiler, S.M. Development of potent thrombin receptor antagonist peptides. J. Med. Chem. 1996, 39, 4879-4887.
20. Seiler, S.M.; Peluso, M.; Michel, I.M.; Goldenberg, H.; Fenton, J.W.; Riexinger, D.; Natarajan, S. Inhibition of thrombin and SFLLR-peptide stimulation of platelet aggregation, phospholipase A2 and Na/H exchange by a thrombin receptor antagonist. Biochem. Pharmacol. 1995, 49, 519-528.
21. van Gorp, R.M.; Feijge, M.A.; Vuist, W.M.; Rook, M.B. Irregular spiking in free calcium concentration in single, human platelets. Eur. J. Biochem. 2002, 269, 1543-1552.