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Volumn 11, Issue 2, 2007, Pages 79-82

Impact of pharmacogenomics on clinical practice in oncology

Author keywords

[No Author keywords available]

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; DEOXYURIDINE PHOSPHATE; FLUOROURACIL; GLUCURONOSYLTRANSFERASE 1A1; IRINOTECAN; MERCAPTOPURINE; OXALIPLATIN; THIOPURINE METHYLTRANSFERASE; THYMIDINE PHOSPHATE; THYMIDYLATE SYNTHASE;

EID: 34147111853     PISSN: 11771062     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03256226     Document Type: Review
Times cited : (19)

References (47)
  • 1
    • 33644825856 scopus 로고    scopus 로고
    • Overall survival of patients with advanced colorectal cancer correlates with availability of fluorouracil, irinotecan, and oxaliplatin regardless of whether doublet or single-agent therapy is used first line
    • Dec 20;
    • Grothey A, Sargent D. Overall survival of patients with advanced colorectal cancer correlates with availability of fluorouracil, irinotecan, and oxaliplatin regardless of whether doublet or single-agent therapy is used first line. J Clin Oncol 2005 Dec 20; 23 (36): 9441-2
    • (2005) J Clin Oncol , vol.23 , Issue.36 , pp. 9441-9442
    • Grothey, A.1    Sargent, D.2
  • 2
    • 30444437486 scopus 로고    scopus 로고
    • Treatment of acute lymphoblastic leukemia
    • Jan 12;
    • Pui CH, Evans WE. Treatment of acute lymphoblastic leukemia. N Engl J Med 2006 Jan 12; 354 (2): 166-78
    • (2006) N Engl J Med , vol.354 , Issue.2 , pp. 166-178
    • Pui, C.H.1    Evans, W.E.2
  • 3
    • 0035865322 scopus 로고    scopus 로고
    • A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms
    • Feb 15;
    • Sachidanandam R, Weissman D, Schmidt SC, et al. A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms. Nature 2001 Feb 15; 409 (6822): 928-33
    • (2001) Nature , vol.409 , Issue.6822 , pp. 928-933
    • Sachidanandam, R.1    Weissman, D.2    Schmidt, S.C.3
  • 4
    • 0037421590 scopus 로고    scopus 로고
    • Pharmacogenomics: Drug disposition, drug targets, and side effects
    • Feb 6;
    • Evans WE, McLeod HL. Pharmacogenomics: drug disposition, drug targets, and side effects. N Engl J Med 2003 Feb 6; 348 (6): 538-49
    • (2003) N Engl J Med , vol.348 , Issue.6 , pp. 538-549
    • Evans, W.E.1    McLeod, H.L.2
  • 5
    • 0842286886 scopus 로고    scopus 로고
    • Cancer pharmacogenetics
    • Jan 12;
    • Marsh S, McLeod HL. Cancer pharmacogenetics. Br J Cancer 2004 Jan 12; 90 (1): 8-11
    • (2004) Br J Cancer , vol.90 , Issue.1 , pp. 8-11
    • Marsh, S.1    McLeod, H.L.2
  • 6
    • 33745775921 scopus 로고    scopus 로고
    • Marsh S, McLeod HL. Pharmacogenomics: from bedside to clinical practice. Hum Mol Genet 2006 Apr 15; 15 (Spec. No. 1.): R89-93
    • Marsh S, McLeod HL. Pharmacogenomics: from bedside to clinical practice. Hum Mol Genet 2006 Apr 15; 15 (Spec. No. 1.): R89-93
  • 7
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • Feb 15;
    • Lander ES, Linton LM, Birren B, et al. Initial sequencing and analysis of the human genome. Nature 2001 Feb 15; 409 (6822): 860-921
    • (2001) Nature , vol.409 , Issue.6822 , pp. 860-921
    • Lander, E.S.1    Linton, L.M.2    Birren, B.3
  • 8
    • 13444293344 scopus 로고    scopus 로고
    • Database resources of the National Center for Biotechnology Information
    • Jan 1;
    • Wheeler DL, Barrett T, Benson DA, et al. Database resources of the National Center for Biotechnology Information. Nucleic Acids Res 2005 Jan 1; 33: D39-45
    • (2005) Nucleic Acids Res , vol.33
    • Wheeler, D.L.1    Barrett, T.2    Benson, D.A.3
  • 9
    • 79959503826 scopus 로고    scopus 로고
    • The International HapMap Project, Dec 18;
    • The International HapMap Project. Nature 2003 Dec 18; 426 (6968): 789-96
    • (2003) Nature , vol.426 , Issue.6968 , pp. 789-796
  • 10
    • 79959524146 scopus 로고    scopus 로고
    • A haplotype map of the human genome
    • Oct 27;
    • Altshuler D, Brooks LD, Chakravarti A, et al. A haplotype map of the human genome. Nature 2005 Oct 27; 437 (7063): 1299-320
    • (2005) Nature , vol.437 , Issue.7063 , pp. 1299-1320
    • Altshuler, D.1    Brooks, L.D.2    Chakravarti, A.3
  • 11
    • 20044369371 scopus 로고    scopus 로고
    • Toward genome-wide SNP genotyping
    • Jun;
    • Syvanen AC. Toward genome-wide SNP genotyping. Nat Genet 2005 Jun; 37S: S5-10
    • (2005) Nat Genet , vol.37 S
    • Syvanen, A.C.1
  • 12
    • 3042767484 scopus 로고    scopus 로고
    • High-throughput genotyping methods for pharmacogenomic studies
    • Freimuth RR, Ameyaw M-M, Pritchard SC, et al. High-throughput genotyping methods for pharmacogenomic studies. Curr Pharmacogenomics 2004; 2 (1): 21-33
    • (2004) Curr Pharmacogenomics , vol.2 , Issue.1 , pp. 21-33
    • Freimuth, R.R.1    Ameyaw, M.-M.2    Pritchard, S.C.3
  • 13
    • 3242686833 scopus 로고    scopus 로고
    • The price tag on progress: Chemotherapy for colorectal cancer
    • Jul 22;
    • Schrag D. The price tag on progress: chemotherapy for colorectal cancer. N Engl J Med 2004 Jul 22; 351 (4): 317-9
    • (2004) N Engl J Med , vol.351 , Issue.4 , pp. 317-319
    • Schrag, D.1
  • 14
    • 0033135738 scopus 로고    scopus 로고
    • Prognostic importance of 6-mercaptopurine dose intensity in acute lymphoblastic leukemia
    • May 1;
    • Relling MV, Hancock ML, Boyett JM, et al. Prognostic importance of 6-mercaptopurine dose intensity in acute lymphoblastic leukemia. Blood 1999 May 1; 93 (9): 2817-23
    • (1999) Blood , vol.93 , Issue.9 , pp. 2817-2823
    • Relling, M.V.1    Hancock, M.L.2    Boyett, J.M.3
  • 15
    • 0036009619 scopus 로고    scopus 로고
    • The thiopurine S-methyltransferase gene locus: Implications for clinical pharmacogenomics
    • Jan;
    • McLeod HL, Siva C. The thiopurine S-methyltransferase gene locus: implications for clinical pharmacogenomics. Pharmacogenomics 2002 Jan; 3 (1): 89-98
    • (2002) Pharmacogenomics , vol.3 , Issue.1 , pp. 89-98
    • McLeod, H.L.1    Siva, C.2
  • 16
    • 0033486029 scopus 로고    scopus 로고
    • Relling MV, Hancock ML, Rivera GK, et al. Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus. J Natl Cancer Inst 1999 Dec 1; 91 (23): 2001-8
    • Relling MV, Hancock ML, Rivera GK, et al. Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus. J Natl Cancer Inst 1999 Dec 1; 91 (23): 2001-8
  • 17
    • 0037364658 scopus 로고    scopus 로고
    • Phase III comparison of two irinotecan dosing regimens in second-line therapy of metastatic colorectal cancer
    • Mar 1;
    • Fuchs CS, Moore MR, Harker G, et al. Phase III comparison of two irinotecan dosing regimens in second-line therapy of metastatic colorectal cancer. J Clin Oncol 2003 Mar 1; 21 (5): 807-14
    • (2003) J Clin Oncol , vol.21 , Issue.5 , pp. 807-814
    • Fuchs, C.S.1    Moore, M.R.2    Harker, G.3
  • 18
    • 0032493441 scopus 로고    scopus 로고
    • Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: A balanced polymorphism for regulation of bilirubin metabolism?
    • Jul 7;
    • Beutler E, Gelbart T, Demina A. Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: a balanced polymorphism for regulation of bilirubin metabolism? Proc Natl Acad Sci U S A 1998 Jul 7; 95 (14): 8170-4
    • (1998) Proc Natl Acad Sci U S A , vol.95 , Issue.14 , pp. 8170-8174
    • Beutler, E.1    Gelbart, T.2    Demina, A.3
  • 19
    • 0034652640 scopus 로고    scopus 로고
    • Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 and association with breast cancer among African Americans
    • Feb 15;
    • Guillemette C, Millikan RC, Newman B, et al. Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 and association with breast cancer among African Americans. Cancer Res 2000 Feb 15; 60 (4): 950-6
    • (2000) Cancer Res , vol.60 , Issue.4 , pp. 950-956
    • Guillemette, C.1    Millikan, R.C.2    Newman, B.3
  • 20
    • 0032718482 scopus 로고    scopus 로고
    • Variability at the uridine diphosphate glucuronosyltransferase 1A1 promoter in human populations and primates
    • Oct;
    • Hall D, Ybazeta G, Destro-Bisol G, et al. Variability at the uridine diphosphate glucuronosyltransferase 1A1 promoter in human populations and primates. Pharmacogenetics 1999 Oct; 9 (5): 591-9
    • (1999) Pharmacogenetics , vol.9 , Issue.5 , pp. 591-599
    • Hall, D.1    Ybazeta, G.2    Destro-Bisol, G.3
  • 21
    • 0034671387 scopus 로고    scopus 로고
    • Polymorphisms of UDP- glucuronosyltransferase gene and irinotecan toxicity: A pharmacogenetic analysis
    • Dec 15;
    • Ando Y, Saka H, Ando M, et al. Polymorphisms of UDP- glucuronosyltransferase gene and irinotecan toxicity: a pharmacogenetic analysis. Cancer Res 2000 Dec 15; 60 (24): 6921-6
    • (2000) Cancer Res , vol.60 , Issue.24 , pp. 6921-6926
    • Ando, Y.1    Saka, H.2    Ando, M.3
  • 22
    • 0141560464 scopus 로고    scopus 로고
    • Irinotecan treatment in cancer patients with UGT1A1 polymorphisms
    • May;
    • Innocenti F, Ratain MJ. Irinotecan treatment in cancer patients with UGT1A1 polymorphisms. Oncology (Huntingt) 2003 May; 17 (5 Suppl. 5): 52-5
    • (2003) Oncology (Huntingt) , vol.17 , Issue.5 SUPPL. 5 , pp. 52-55
    • Innocenti, F.1    Ratain, M.J.2
  • 23
    • 0032934383 scopus 로고    scopus 로고
    • Phenotype-genotype correlation of in vitro SN-38 (active metabolite of irinotecan) and bilirubin glucuronidation in human liver tissue with UGT1A1 promoter polymorphism
    • May;
    • Iyer L, Hall D, Das S, et al. Phenotype-genotype correlation of in vitro SN-38 (active metabolite of irinotecan) and bilirubin glucuronidation in human liver tissue with UGT1A1 promoter polymorphism. Clin Pharmacol Ther 1999 May; 65 (5): 576-82
    • (1999) Clin Pharmacol Ther , vol.65 , Issue.5 , pp. 576-582
    • Iyer, L.1    Hall, D.2    Das, S.3
  • 24
    • 0036025450 scopus 로고    scopus 로고
    • UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity
    • Iyer L, Das S, Janisch L, et al. UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity. Pharmacogenomics J 2002; 2 (1): 43-7
    • (2002) Pharmacogenomics J , vol.2 , Issue.1 , pp. 43-47
    • Iyer, L.1    Das, S.2    Janisch, L.3
  • 25
    • 2342459714 scopus 로고    scopus 로고
    • Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan
    • Apr 15;
    • Innocenti F, Undevia SD, Iyer L, et al. Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan. J Clin Oncol 2004 Apr 15; 22 (8): 1382-8
    • (2004) J Clin Oncol , vol.22 , Issue.8 , pp. 1382-1388
    • Innocenti, F.1    Undevia, S.D.2    Iyer, L.3
  • 26
    • 33745141299 scopus 로고    scopus 로고
    • FDA clears Third Wave pharmacogenetic test
    • FDA clears Third Wave pharmacogenetic test. Pharmacogenomics 2005; 6 (7): 671-2
    • (2005) Pharmacogenomics , vol.6 , Issue.7 , pp. 671-672
  • 27
    • 29244433547 scopus 로고    scopus 로고
    • Irinotecan (CPT-11) pharmacokinetics (PK) and neutropenia: Interaction among UGT1A1 and transporter genes [abstract]
    • 136s
    • Innocenti F, Undevia SD, Rosner GL, et al. Irinotecan (CPT-11) pharmacokinetics (PK) and neutropenia: interaction among UGT1A1 and transporter genes [abstract]. Proc Am Soc Clin Oncol 2005; 23: 136s
    • (2005) Proc Am Soc Clin Oncol , vol.23
    • Innocenti, F.1    Undevia, S.D.2    Rosner, G.L.3
  • 28
    • 2942527225 scopus 로고    scopus 로고
    • UGT1A1 haplotypes associated with reduced glucuronidation and increased serum bilirubin in irinotecan-administered Japanese patients with cancer
    • Jun;
    • Sai K, Saeki M, Saito Y, et al. UGT1A1 haplotypes associated with reduced glucuronidation and increased serum bilirubin in irinotecan-administered Japanese patients with cancer. Clin Pharmacol Ther 2004 Jun; 75 (6): 501-15
    • (2004) Clin Pharmacol Ther , vol.75 , Issue.6 , pp. 501-515
    • Sai, K.1    Saeki, M.2    Saito, Y.3
  • 29
    • 6344231838 scopus 로고    scopus 로고
    • Pharmacogenetics of irinotecan toxicity
    • Oct;
    • Marsh S, McLeod HL. Pharmacogenetics of irinotecan toxicity. Pharmacogenomics 2004 Oct; 5 (7): 835-43
    • (2004) Pharmacogenomics , vol.5 , Issue.7 , pp. 835-843
    • Marsh, S.1    McLeod, H.L.2
  • 30
    • 33846012498 scopus 로고    scopus 로고
    • Irinotecan-induced diarrhea: Functional significance of polymorphic ABCC2 transporter protein
    • Jan;
    • de Jong FA, Scott-Horton TJ, Kroetz DL, et al. Irinotecan-induced diarrhea: functional significance of polymorphic ABCC2 transporter protein. Clin Pharmacol Ther 2007 Jan; 81 (1): 42-9
    • (2007) Clin Pharmacol Ther , vol.81 , Issue.1 , pp. 42-49
    • de Jong, F.A.1    Scott-Horton, T.J.2    Kroetz, D.L.3
  • 31
    • 0028940399 scopus 로고
    • Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors
    • Apr 1;
    • Johnston PG, Lenz HJ, Leichman CG, et al. Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors. Cancer Res 1995 Apr 1; 55 (7): 1407-12
    • (1995) Cancer Res , vol.55 , Issue.7 , pp. 1407-1412
    • Johnston, P.G.1    Lenz, H.J.2    Leichman, C.G.3
  • 32
    • 0030883708 scopus 로고    scopus 로고
    • Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted-infusion fluorouracil and weekly leucovorin
    • Oct;
    • Leichman CG, Lenz HJ, Leichman L, et al. Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted-infusion fluorouracil and weekly leucovorin. J Clin Oncol 1997 Oct; 15 (10): 3223-9
    • (1997) J Clin Oncol , vol.15 , Issue.10 , pp. 3223-3229
    • Leichman, C.G.1    Lenz, H.J.2    Leichman, L.3
  • 33
    • 31544462629 scopus 로고    scopus 로고
    • Thymidylate synthase pharmacogenetics
    • Dec;
    • Marsh S. Thymidylate synthase pharmacogenetics. Invest New Drugs 2005 Dec; 23 (6): 533-7
    • (2005) Invest New Drugs , vol.23 , Issue.6 , pp. 533-537
    • Marsh, S.1
  • 34
    • 0029122937 scopus 로고
    • Functional analysis and DNA polymorphism of the tandemly repeated sequences in the 5′-terminal regulatory region of the human gene for thymidylate synthase
    • Jun;
    • Horie N, Aiba H, Oguro K, et al. Functional analysis and DNA polymorphism of the tandemly repeated sequences in the 5′-terminal regulatory region of the human gene for thymidylate synthase. Cell Struct Funct 1995 Jun; 20 (3): 191-7
    • (1995) Cell Struct Funct , vol.20 , Issue.3 , pp. 191-197
    • Horie, N.1    Aiba, H.2    Oguro, K.3
  • 35
    • 0037567591 scopus 로고    scopus 로고
    • A novel single nucleotide polymorphism within the 5? tandem repeat polymorphism of the thymidylate synthase gene abolishes USF-1 binding and alters transcriptional activity
    • Jun 1;
    • Mandola MV, Stoehlmacher J, Muller-Weeks S, et al. A novel single nucleotide polymorphism within the 5? tandem repeat polymorphism of the thymidylate synthase gene abolishes USF-1 binding and alters transcriptional activity. Cancer Res 2003 Jun 1; 63 (11): 2898-904
    • (2003) Cancer Res , vol.63 , Issue.11 , pp. 2898-2904
    • Mandola, M.V.1    Stoehlmacher, J.2    Muller-Weeks, S.3
  • 36
    • 0034518362 scopus 로고    scopus 로고
    • Searching expressed sequence tag databases: Discovery and confirmation of a common polymorphism in the thymidylate synthase gene
    • Dec;
    • Ulrich CM, Bigler J, Velicer CM, et al. Searching expressed sequence tag databases: discovery and confirmation of a common polymorphism in the thymidylate synthase gene. Cancer Epidemiol Biomarkers Prev 2000 Dec; 9 (12): 1381-5
    • (2000) Cancer Epidemiol Biomarkers Prev , vol.9 , Issue.12 , pp. 1381-1385
    • Ulrich, C.M.1    Bigler, J.2    Velicer, C.M.3
  • 37
    • 0034548477 scopus 로고    scopus 로고
    • Novel thymidylate synthase enhancer region alleles in African populations
    • Dec;
    • Marsh S, Ameyaw MM, Githang'a J, et al. Novel thymidylate synthase enhancer region alleles in African populations. Hum Mutat 2000 Dec; 16 (6): 528
    • (2000) Hum Mutat , vol.16 , Issue.6 , pp. 528
    • Marsh, S.1    Ameyaw, M.M.2    Githang'a, J.3
  • 38
    • 0036102129 scopus 로고    scopus 로고
    • Length polymorphism of thymidylate synthase regulatory region in Chinese populations and evolution of the novel alleles
    • Feb;
    • Luo HR, Lu XM, Yao YG, et al. Length polymorphism of thymidylate synthase regulatory region in Chinese populations and evolution of the novel alleles. Biochem Genet 2002 Feb; 40 (1-2): 41-51
    • (2002) Biochem Genet , vol.40 , Issue.1-2 , pp. 41-51
    • Luo, H.R.1    Lu, X.M.2    Yao, Y.G.3
  • 39
    • 0033427561 scopus 로고    scopus 로고
    • Kawakami K, Omura K, Kanehira E, et al. Polymorphic tandem repeats in the thymidylate synthase gene is associated with its protein expression in human gastrointestinal cancers. Anticancer Res 1999 Jul-Aug; 19 (4B): 3249-52
    • Kawakami K, Omura K, Kanehira E, et al. Polymorphic tandem repeats in the thymidylate synthase gene is associated with its protein expression in human gastrointestinal cancers. Anticancer Res 1999 Jul-Aug; 19 (4B): 3249-52
  • 40
    • 0033564283 scopus 로고    scopus 로고
    • Ethnic variation in the thymidylate synthase enhancer region polymorphism among Caucasian and Asian populations
    • Jun 15;
    • Marsh S, Collie-Duguid ES, Li T, et al. Ethnic variation in the thymidylate synthase enhancer region polymorphism among Caucasian and Asian populations. Genomics 1999 Jun 15; 58 (3): 310-2
    • (1999) Genomics , vol.58 , Issue.3 , pp. 310-312
    • Marsh, S.1    Collie-Duguid, E.S.2    Li, T.3
  • 41
    • 0035522659 scopus 로고    scopus 로고
    • Thymidylate synthase pharmacogenetics in colorectal cancer
    • Nov;, discussion 79-81
    • Marsh S, McLeod HL. Thymidylate synthase pharmacogenetics in colorectal cancer. Clin Colorectal Cancer 2001 Nov; 1 (3): 175-8; discussion 79-81
    • (2001) Clin Colorectal Cancer , vol.1 , Issue.3 , pp. 175-178
    • Marsh, S.1    McLeod, H.L.2
  • 42
    • 0029435028 scopus 로고
    • Functional structure of the promoter region of the human thymidylate synthase gene and nuclear factors that regulate the expression of the gene
    • Horie N, Takeishi K. Functional structure of the promoter region of the human thymidylate synthase gene and nuclear factors that regulate the expression of the gene. Nucleic Acids Symp Ser 1995; (34): 77-8
    • (1995) Nucleic Acids Symp Ser , vol.34 , pp. 77-78
    • Horie, N.1    Takeishi, K.2
  • 43
    • 0035868667 scopus 로고    scopus 로고
    • Polymorphisms of the repeated sequences in the enhancer region of the thymidylate synthase gene promoter may predict downstaging after preoperative chemoradiation in rectal cancer
    • Mar 15;
    • Villafranca E, Okruzhnov Y, Dominguez MA, et al. Polymorphisms of the repeated sequences in the enhancer region of the thymidylate synthase gene promoter may predict downstaging after preoperative chemoradiation in rectal cancer. J Clin Oncol 2001 Mar 15; 19 (6): 1779-86
    • (2001) J Clin Oncol , vol.19 , Issue.6 , pp. 1779-1786
    • Villafranca, E.1    Okruzhnov, Y.2    Dominguez, M.A.3
  • 44
    • 0035750549 scopus 로고    scopus 로고
    • Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy
    • Pullarkat ST, Stoehlmacher J, Ghaderi V, et al. Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy. Pharmacogenomics J 2001; 1 (1): 65-70
    • (2001) Pharmacogenomics J , vol.1 , Issue.1 , pp. 65-70
    • Pullarkat, S.T.1    Stoehlmacher, J.2    Ghaderi, V.3
  • 45
    • 4444339951 scopus 로고    scopus 로고
    • Thymidylate synthase gene polymorphism predicts toxicity in colorectal cancer patients receiving 5-fluorouracil-based chemotherapy
    • Sep 1;
    • Lecomte T, Ferraz JM, Zinzindohoue F, et al. Thymidylate synthase gene polymorphism predicts toxicity in colorectal cancer patients receiving 5-fluorouracil-based chemotherapy. Clin Cancer Res 2004 Sep 1; 10 (17): 5880-8
    • (2004) Clin Cancer Res , vol.10 , Issue.17 , pp. 5880-5888
    • Lecomte, T.1    Ferraz, J.M.2    Zinzindohoue, F.3
  • 46
    • 0035860142 scopus 로고    scopus 로고
    • A polymorphism in the enhancer region of the thymidylate synthase promoter influences the survival of colorectal cancer patients treated with 5-fluorouracil
    • Sep 14;
    • Iacopetta B, Grieu F, Joseph D, et al. A polymorphism in the enhancer region of the thymidylate synthase promoter influences the survival of colorectal cancer patients treated with 5-fluorouracil. Br J Cancer 2001 Sep 14; 85 (6): 827-30
    • (2001) Br J Cancer , vol.85 , Issue.6 , pp. 827-830
    • Iacopetta, B.1    Grieu, F.2    Joseph, D.3
  • 47
    • 29244482298 scopus 로고    scopus 로고
    • Genotype-guided neoadjuvant therapy for rectal cancer [abstract]
    • McLeod HL, Tan B, Malyapa R, et al. Genotype-guided neoadjuvant therapy for rectal cancer [abstract]. Proc Am Soc Clin Oncol 2005; 23: 197
    • (2005) Proc Am Soc Clin Oncol , vol.23 , pp. 197
    • McLeod, H.L.1    Tan, B.2    Malyapa, R.3


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