Maintaining the life-long vitality and integrity of skeletal tissue

Bone

Volumn 40, Issue 5 SUPPL., 2007, Pages

  Raisz, Lawrence G ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

Ageing; Bone remodelling; Osteocyte; Osteoporosis; Wnt signalling

Indexed keywords

COLONY STIMULATING FACTOR 1; CYTOKINE; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; OSTEOCLAST DIFFERENTIATION FACTOR; WNT PROTEIN;

ADOLESCENCE; AGING; ARTICLE; BONE FRAGILITY; BONE MASS; BONE REMODELING; BONE STRENGTH; BONE TISSUE; CHILDHOOD; HEREDITY; HUMAN; LIFESTYLE; OSSIFICATION; OSTEOBLAST; OSTEOCLAST; OSTEOLYSIS; OSTEOPOROSIS; PHYSICAL MOBILITY; SIGNAL TRANSDUCTION;

EID: 34147099583     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2007.02.002     Document Type: Article

References (41)

1. Cooper A. A treatise on dislocations, and on fractures of the joints (1822).
2. Albright F., Bloomberg E., and Smith P.H. Postmenopausal osteoporosis. Trans. Assoc. Am. Physicians 55 (1940) 298-305
3. Schapira D., and Schapira C. Osteoporosis: the evolution of a scientific term. Osteoporos. Int. 2 (1992) 164-167
4. Cooper C. Epidemiology of osteoporotic fracture: looking to the future. Rheumatology (Oxford) 44 Suppl. 4 (2005) iv36-iv40
5. Raisz L.G. Pathogenesis of osteoporosis: concepts, conflicts, and prospects. J. Clin. Invest. 115 (2005) 3318-3325
6. Yang F., Shen H., Jiang H., and Deng H.W. On genetic studies of bone loss. J. Bone Miner. Res. 21 (2006) 1676-1677
7. Gong Y., Slee R.B., Fukai N., Rawadi G., Roman-Roman S., Reginato A.M., et al. LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development. Cell 107 (2001) 513-523
8. Cooper C., Westlake S., Harvey N., Javaid K., Dennison E., and Hanson M. Review: developmental origins of osteoporotic fracture. Osteoporos. Int. 17 (2006) 337-347
9. Falahati-Nini C., Riggs B.L., Atkinson E.J., O'Fallon W.M., Eastell R., and Khosla S. Relative contributions of testosterone and estrogen in regulating bone resorption and formation in normal elderly men. J. Clin. Invest. 106 (2000) 1553-1560
10. Khosla S., Melton III L.J., Atkinson E.J., and O'Fallon W.M. Relationship of serum sex steroid levels to longitudinal changes in bone density in young versus elderly men. J. Clin. Endocrinol. Metab. 86 (2001) 3555-3561
11. Van Pottelbergh I., Goemaere S., Zmierczak H., and Kaufman J.M. Perturbed sex steroid status in men with idiopathic osteoporosis and their sons. J. Clin. Endocrinol. Metab. 89 (2004) 4949-4953
12. Lips P. Which circulating level of 25-hydroxyvitamin D is appropriate?. J. Steroid Biochem. Mol. Biol. 89-90 (2004) 611-614
13. Riggs B.L., Wahner H.W., Seeman E., Offord K.P., Dunn W.L., Mazess R.B., et al. Changes in bone mineral density of the proximal femur and spine with aging. Differences between the postmenopausal and senile osteoporosis syndromes. J. Clin. Invest. 70 (1982) 716-723
14. Lips P., Courpron P., and Meunier P.J. Mean wall thickness of trabecular bone packets in the human iliac crest: changes with age. Calcif. Tissue Res. 26 (1978) 13-17
15. Mundy G.R. Nutritional modulators of bone remodeling during aging. Am. J. Clin. Nutr. 83 (2006) 427S-430S
16. Rosen C.J. Insulin-like growth factor I and bone mineral density: experience from animal models and human observational studies. Best Pract. Res. Clin. Endocrinol. Metab. 18 (2004) 423-435
17. O'Brien C.A., Jia D., Plotkin L.I., Bellido T., Powers C.C., Stewart S.A., et al. Glucocorticoids act directly on osteoblasts and osteocytes to induce their apoptosis and reduce bone formation and strength. Endocrinology 145 (2004) 1835-1841
18. Qiu S., Rao D.S., Fyhrie D.P., Palnitkar S., and Parfitt A.M. The morphological association between microcracks and osteocyte lacunae in human cortical bone. Bone 37 (2005) 10-15
19. Bellido T., Ali A.A., Gubrij I., Plotkin L.I., Fu Q., O'Brien C.A., et al. Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: a novel mechanism for hormonal control of osteoblastogenesis. Endocrinology 146 (2005) 4577-4583
20. Keller H., and Kneissel M. SOST is a target gene for PTH in bone. Bone 37 (2005) 148-158
21. Kulkarni N.H., Halladay D.L., Miles R.R., Gilbert L.M., Frolik C.A., Galvin R.J., et al. Effects of parathyroid hormone on Wnt signaling pathway in bone. J. Cell. Biochem. 95 (2005) 1178-1190
22. Veno P., Nicolella D.P., Sivakumar P., Kalajzic I., Rowe D.W., Bonewald L.F., et al. Live imaging of osteocytes within their lacunae reveals cell body and dendrite motions. J. Bone Miner. Res. 21 (2006) S38
23. Chow J.W., Fox S.W., Lean J.M., and Chambers T.J. Role of nitric oxide and prostaglandins in mechanically induced bone formation. J. Bone Miner. Res. 13 (1998) 1039-1044
24. Vezeridis P.S., Semeins C.M., Chen Q., and Klein-Nulend J. Osteocytes subjected to pulsating fluid flow regulate osteoblast proliferation and differentiation. Biochem. Biophys. Res. Commun. 348 (2006) 1082-1088
25. Wadhwa S., Choudhary S., Voznesensky M., Epstein M., Raisz L., and Pilbeam C. Fluid flow induces COX-2 expression in MC3T3-E1 osteoblasts via a PKA signaling pathway. Biochem. Biophys. Res. Commun. 297 (2002) 46-51
26. Forwood M.R. Inducible cyclo-oxygenase (COX-2) mediates the induction of bone formation by mechanical loading in vivo. J. Bone Miner. Res. 11 (1996) 1688-1693
27. Mullender M.G., van der Meer D.D., Huiskes R., and Lips P. Osteocyte density changes in aging and osteoporosis. Bone 18 (1996) 109-113
28. Power J., Loveridge N., Rushton N., Parker M., and Reeve J. Osteocyte density in aging subjects is enhanced in bone adjacent to remodeling haversian systems. Bone 30 (2002) 859-865
29. Boyden L.M., Mao J., Belsky J., Mitzner L., Farhi A., Mitnick M.A., et al. High bone density due to a mutation in LDL-receptor-related protein 5. N. Engl. J. Med. 346 (2002) 1513-1521
30. Little R.D., Carulli J.P., Del Mastro R.G., Dupuis J., Osborne M., Folz C., et al. A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait. Am. J. Hum. Genet. 70 (2002) 11-19
31. Van Wesenbeeck L., Cleiren E., Gram J., Beals R.K., Benichou O., Scopelliti D., et al. Six novel missense mutations in the LDL receptor-related protein 5 (LRP5) gene in different conditions with an increased bone density. Am. J. Hum. Genet. 72 (2003) 763-771
32. Li X., Zhang Y., Kang H., Liu W., Liu P., Zhang J., et al. Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling. J. Biol. Chem. 80 (2005) 19883-19887
33. Morvan F., Boulukos K., Clement-Lacroix P., Roman-Roman S., Suc-Royer B.I., Vayssiere P., et al. Deletion of a single allele of the Dkk1 gene leads to an increase in bone formation and bone mass. J. Bone Miner. Res. 21 (2006) 934-945
34. Bollerslev J., Wilson S.G., Dick I.M., Islam F.M., Ueland T., Palmer L., et al. LRP5 gene polymorphisms predict bone mass and incident fractures in elderly Australian women. Bone 36 (2005) 599-606
35. Hartikka H., Makitie O., Mannikko M., Doria A.S., Daneman A., Cole W.G., et al. Heterozygous mutations in the LDL receptor-related protein 5 (LRP5) gene are associated with primary osteoporosis in children. J. Bone Miner. Res. 20 (2005) 783-789
36. Mizuguchi T., Furuta I., Watanabe Y., Tsukamoto K., Tomita H., Tsujihata M., et al. LRP5, low-density-lipoprotein-receptor-related protein 5, is a determinant for bone mineral density. J. Hum. Genet. 49 (2004) 80-86
37. Balemans W., Ebeling M., Patel N., Van Hul E., Olson P., Dioszegi M., et al. Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST). Hum. Mol. Genet. 10 (2001) 537-543
38. Gardner J.C., van Bezooijen R.L., Mervis B., Hamdy N.A., Lowik C.W., Hamersma H., et al. Bone mineral density in sclerosteosis; affected individuals and gene carriers. J. Clin. Endocrinol. Metab. 90 (2005) 6392-6395
39. Mbalaviele G., Sheikh S., Stains J.P., Salazar V.S., Cheng S.L., Chen D., et al. beta-Catenin and BMP-2 synergize to promote osteoblast differentiation and new bone formation. J. Cell. Biochem. 94 (2005) 403-418
40. Nakashima K., Zhou X., Kunkel G., Zhang Z., Deng J.M., Behringer R.R., et al. The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell 108 (2002) 17-29
41. Rawadi G., Vayssiere B., Dunn F., Baron R., and Roman-Roman S. BMP-2 controls alkaline phosphatase expression and osteoblast mineralization by a Wnt autocrine loop. J. Bone Miner. Res. 18 (2003) 1842-1853