Role of heat shock protein 47, a collagen-binding chaperone, in lacrimal gland pathology in patients with cGVHD

Investigative Ophthalmology and Visual Science

Volumn 48, Issue 3, 2007, Pages 1079-1086

  Ogawa, Yoko ^a   Razzaque, Mohammed S ^b   Kameyama, Kaori ^a   Hasegawa, Go ^a   Shimmura, Shigeto ^a   Kawai, Masataka ^a   Okamoto, Shinichiro ^a   Ikeda, Yasuo ^a   Tsubota, Kazuo ^a   Kawakami, Yutaka ^a   Kuwana, Masataka ^a  

^a KEIO UNIVERSITY   (Japan)

^b HARVARD SCHOOL OF DENTAL MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CHAPERONE; COLLAGEN BINDING PROTEIN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; HEAT SHOCK PROTEIN 47; KI 67 ANTIGEN; MESSENGER RNA; ACTIN; SERPINH1 PROTEIN, HUMAN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CELL DIFFERENTIATION; CHRONIC GRAFT VERSUS HOST DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FIBROBLAST; FIBROBLAST CULTURE; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LACRIMAL GLAND; LACRIMAL GLAND DISEASE; MALE; MYOFIBROBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SJOEGREN SYNDROME; STATISTICAL ANALYSIS; TISSUE SECTION; TRANSMISSION ELECTRON MICROSCOPY; BONE MARROW CELL; CELL CULTURE; CHRONIC DISEASE; ENZYME IMMUNOASSAY; FIBROSIS; GRAFT VERSUS HOST REACTION; LACRIMAL APPARATUS; METABOLISM; PATHOLOGY;

ACTINS; ADULT; BONE MARROW CELLS; CELLS, CULTURED; CHRONIC DISEASE; COLLAGEN TYPE I; COLLAGEN TYPE III; FEMALE; FIBROBLASTS; FIBROSIS; GRAFT VS HOST DISEASE; HSP47 HEAT-SHOCK PROTEINS; HUMANS; IMMUNOBLOTTING; IMMUNOENZYME TECHNIQUES; KI-67 ANTIGEN; LACRIMAL APPARATUS; MALE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SJOGREN'S SYNDROME;

EID: 34047262165     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.06-0601     Document Type: Article

References (42)

1. Ferrara JLM, Antin J. The pathophysiology of graft-vs.-host disease. In: Blume KG, Forman SJ, Applebaum FR, eds. Thomas' Hematopoietic Cell Transplantation. 3rd ed. Malden, MA: Blackwell; 2004;353-368.
2. Vogelsang GB, Lee L, Bensen-Kennedy DM. Pathogenesis and treatment of graft-versus-host disease after bone marrow transplant. Annu Rev Med. 2003;54:29-52.
3. Tichelli A, Duell T, Weiss M, et al. Late-onset keratoconjunctivitis sicca syndrome after bone marrow transplantation: incidence and risk factors. Bone Marrow Transplant. 1996;17:1105-1111.
4. Ogawa Y, Okamoto S, Wakui M, et al. Dry eye after haematopoietic stem cell transplantation. Br J Ophthalmol. 1999;83:1125-1130.
5. Ogawa Y, Yamazaki K, Kuwana M, et al. A significant role of stromal fibroblasts in rapidly progressive dry eye in patients with chronic GVHD. Invest Ophthalmol Vis Sci. 2001;42:111-119.
6. Ogawa Y, Kuwana M, Yamazaki K, et al. Periductal area as the primary site for T-cell activation in lacrimal gland chronic graft-versus-host disease. Invest Ophthalmol Vis Sci. 2003:44:1888-1896.
7. Nagai N, Hosokawa M, Itohara S, et al. Embryonic lethality of molecular chaperone hsp47 knockout mice is associated with defects in collagen biosynthesis. J Cell Biol. 2000;150:1499-1506.
8. Razzaque MS, Foster CS, Ahmed AR. Role of collagen-binding heat shock protein 47 and transforming growth factor-beta1 in conjunctival scarring in ocular cicatricial pemphigoid. Invest Ophthalmol Vis Sci. 2003;44:1616-1621.
9. Razzaque MS, Taguchi T. The possible role of colligin/HSP47, a collagen-binding protein, in the pathogenesis of human and experimental fibrotic diseases. Histol Histopathol. 1999;14:1199-1212.
10. Razzaque MS, Le VT, Taguchi T. Heat shock protein 47 and renal fibrogenesis. Contrib Nephrol. 2005;148:57-59.
11. Murakami S, Toda Y, Seki T, et al. Heat shock protein (HSP) 47 and collagen are upregulated during neointimal formation in the balloon-injured rat carotid artery. Atherosclerosis. 2001;157:361-368.
12. Masuda H, Fukumoto M, Hirayoshi K, Nagata K. Coexpression of the collagen-binding stress protein HSP47 gene and the alpha 1(I) and alpha 1(III) collagen genes in carbon tetrachloride-induced rat liver fibrosis. J Clin Invest. 1994;94:2481-2488.
13. Naitoh M, Hosokawa N, Kubota H, et al. Upregulation of HSP47 and collagen type III in the dermal fibrotic disease, keloid. Biochem Biophys Res Commun. 2001;289:1316-1322.
14. Zha Y, Le VT, Higami Y, Shimokawa I, Taguchi T, Razzaque MS. Life-long suppression of growth hormone-insulin-like growth factor-1 activity in genetically altered rats could prevent age-related renal damage. Endocrinology. 2006;147:5690-5698.
15. Scholzen T, Gerdes J. The Ki67 protein: from the known and the unknown. J Cell Physiol. 2000;182:311-322.
16. Ogawa Y, Kodama H, Kameyama K, et al. Donor fibroblast chimerism in the pathogenic fibrotic lesion of human chronic graft-versus-host disease. Invest Ophthalmol Vis Sci 2005;46:4519-4527.
17. Shulman HM, Sullivan KM, Weiden PL, et al. Chronic graft-versus-host syndrome in man: a long-term clinicopathologic study of 20 Seattle patients. Am J Med. 1980;69:204-217.
18. Fox RI, Robinson CA, Curd JG Kozin F, Howell FV. Sjögren's syndrome: proposed criteria for classification, Arthritis Rheum. 1986;29:577-585.
19. Fox RI. Sjogren's syndrome. Lancet. 2005;366:321-331.
20. Lemp M. Report of the National Eye Institute/Industry Workshop on Clinical Trials on Dry Eye. CLAO J. 1995;21:221-232.
21. Tsubota K. The importance of Schirmer test with nasal stimulation test. Am J Ophthalmol. 1991;111:106-108.
22. Razzaque MS, Taguchi T. Collagen-binding heat shock protein (HSP) 47 expression in anti-thymocyte serum (ATS)-induced glomerulonephritis. J Pathol. 1997;183:24-29.
23. Razzaque: MS, Nazneen A, Taguchi T. Immunolocalization of collagen and collagen-binding heat shock protein 47 in fibrotic lung diseases. Mod Pathol. 1998;11:1183-1188.
24. + monocytes as a source of progenitors that exhibit mesenchymal cell differentiation. J Leukoc Biol. 2003;74:833-845.
25. O'Neill RR, Mitchell LG, Merril CR, Rasband WS. Use of image analysis to quantitate changes in form of mitochondrial DNA after x-irradiation. Appl Theor Electrophor. 1989;1:163-167.
26. Hashimoto N, Jin H, Liu T, Chensue SW, Phan SH. Bone marrow-derived progenitor cells in pulmonary fibrosis. J Clin Invest. 2004;113:243-252.
27. Razzaque MS, Taguchi T. Pulmonary fibrosis: cellular and molecular events. Pathol Int. 2003;53:133-145.
28. Kalluri R, Neilson EG. Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest. 2003;112:1776-1784.
29. Shimmura S, Kawakita T. Accessory cell populations in the cornea. Ocul Surf. 2006;4:74-80.
30. Rastaldi MP, Ferrario F, Giardino L, et al. Epithelial-mesenchymal transition of tubular epithelial cells in human renal biopsies. Kidney Int. 2002;62:137-146.
31. Iwano M, Plieth D, Danoff TM, Xue C, Okada H, Neilson EG. Evidence that fibroblasts derive from epithelium during tissue fibrosis. J Clin Invest. 2002;110:341-350.
32. Bhowmick NA, Chytil A, Plieth D, et al. TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia. Science. 2004;303:848-851.
33. Bhowmick NA, Moses HL. Tumor-stroma interactions. Curr Opin Genet Dev. 2005;15:97-101.
34. Razzaque MS, Hossain MA, Kohno S, Taguchi T. Bleomycin-induced pulmonary fibrosis in rat is associated with increased expression of collagen-binding heat shock protein (HSP) 47. Virchows Arch. 1998;432:455-460.
35. Tomasek JJ, Gabbiani G, Hinz B, Chaponnier C, Brown RA. Myofibroblasts and mechano-regulation of connective tissue remodelling. Nat Rev Mol Cell Biol. 2002;3:349-363.
36. Nozaki Y, Liu T, Hatano K, Gharaee-Kermani M, Phan SH. Induction of telomerase activity in fibroblasts from bleomycin-injured lungs. Am J Respir Cell Mol Biol. 2000;23:460-465.
37. Dunsmore SE, Shapiro SD. The bone marrow leaves its scar: new concepts in pulmonary fibrosis. J Clin Invest. 2004;113:180-182.
38. Boklan, J, Nanjangud G, MacKenzie KL, May C, Sadelain M, Moore MA. Limited proliferation and telomere dysfunction following telomerase inhibition in immortal murine fibroblasts. Cancer Res. 2002;62:2104-2114.
39. Ishii G, Sangai T, Sugiyama K, et al. In vivo characterization of bone marrow-derived fibroblasts recruited into fibrotic lesions. Stem Cells. 2005;23:699-706.
40. Abe K, Ozono Y, Miyazaki M, et al. Interstitial expression of heat shock protein 47 and alpha-smooth muscle actin in renal allograft failure. Nephron Dial Transplant. 2000;15:529-535.
41. Sunamoto M, Kuze K, Tsuji H, et al. Antisense oligonucleotides against collagen-binding stress protein HSP47 suppress collagen accumulation in experimental glomerulonephritis. Lab Invest. 1998;78:967-972.
42. Wang Z, Inokuchi T, Nemoto TK, Uehara M, Baba TT. Antisense oligonucleotide against collagen-specific molecular chaperone 47-kDa heat shock protein suppresses scar formation in rat wounds. Plast Reconstr Surg. 2003;111:1980-1987.