Antisense oligonucleotides against collagen-binding stress protein HSP47 suppress collagen accumulation in experimental glomerulonephritis

Laboratory Investigation

Volumn 78, Issue 8, 1998, Pages 967-972

  Sunamoto, Masaaki ^a   Kuze, Kogo ^a   Tsuji, Hiroko ^a   Ohishi, Nobuko ^c   Yagi, Kunio ^b,c   Nagata, Kazuhiro ^e   Kita, Toru ^a   Doi, Toshio ^a,d  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c Institute of Applied Biochemistry   (Japan)

^d KYOTO UNIVERSITY HOSPITAL   (Japan)

^e NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 47; UNCLASSIFIED DRUG;

ALLERGIC GLOMERULONEPHRITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COLLAGEN METABOLISM; FIBROSIS; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; PROTEIN TARGETING; RAT;

ANIMALS; COLLAGEN; DISEASE MODELS, ANIMAL; GLOMERULONEPHRITIS; HEAT-SHOCK PROTEINS; HSP47 HEAT-SHOCK PROTEINS; MALE; OLIGONUCLEOTIDES, ANTISENSE; PROTEIN BINDING; RATS; RATS, WISTAR; THIONUCLEOTIDES;

EID: 0031818036     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Akagi Y, Isaka Y, Arai M, Kaneko T, Takenaka M, Moriyama T, Kaneda Y, Ando A, Orita Y, Kamada T, Ueda N, and Imai E (1996). Inhibition of TGF-β1 expression by antisense oligo-nucleotides suppressed extracellular matrix accumulation in experimental glomerulonephritis. Kidney Int 50:148-155.
2. Doi T, Striker LJ, Kimata K, Peten EP, Yamada Y, and Striker GE (1991). Glomerulosclerosis in mice transgenic for growth hormone. J Exp Med 173:1287-1290.
3. Floege J, Johnson RJ, Gordon K, Iida H, Pritzl P, Yoshimura A, Campbell C, Alpers CE, and Couser WG (1991). Increased synthesis of extracellular matrix in mesangial proliferative nephritis. Kidney Int 40:477-488.
4. Kitamura M, Burton S, English J, Kawachi H, and Fine LG (1995). Transfer of a mutated gene encoding active transforming growth factor-β1 suppresses mitogenesis and IL-1 response in the glomerulus. Kidney Int 48:1747-1757.
5. Kitamura M (1997). Strategic gene transfer into the kidney: Current status and prospects. Clin Exp Nephrol 1:157-178.
6. Klahr S, Schreiner G, and Ichikawa I (1988). The progression of renal disease. N Engl J Med 318:1657-1666.
7. Kojima H, Ohishi N, Takamori M, and Yagi K (1995). Cationic multilamellar liposome-mediated gene transfer into primary myoblasts. Biochem Biophys Res Commun 207:8-12.
8. Lipkowitz MS, Klotman ME, Bruggeman LA, Nicklin P, Hanss B, Rappaport J, and Klotman PE (1996). Molecular therapy for renal diseases. Am J Kidney Dis 28:475-492.
9. Masuda H, Fukumoto M, Hirayoshi K, and Nagata K (1994). Coexpression of the collagen-binding stress protein HSP47 gene and the α1(I) and α1(III) collagen genes in carbon tetrachloride-induced rat liver fibrosis. J Clin Invest 94:2481-2488.
10. Nagata K (1996). HSP47: A collagen-specific molecular chaperone. Trends Biochem Sci 21:23-26.
11. Nagata K and Yamada KM (1986). Phosphorylation and transformation sensitivity of a major collagen-binding protein of fibroblasts. J Biol Chem 261:7531-7536.
12. Nakai A, Hirayoshi K, Saga S, Yamada KM, and Nagata K (1989). The transformation-sensitive heat shock protein (HSP47) binds specifically to feutin. Biochem Biophys Res Commun 164:259-264.
13. Nakai A, Satoh M, Hirayoshi K, and Nagata K (1992). Involvement of the stress protein HSP47 in procollagen processing in the endoplasmic reticulum. J Cell Biol 117:903-914.
14. Natsume T, Koide T, Yokota S, Hirayoshi K, and Nagata K (1994). Interactions between collagen-binding stress protein HSP47 and collagen. J Biol Chem 269:31224-31228.
15. Raij L, Azar S, and Keane W (1984). Mesangial immune injury, hypertension, and progressive glomerular damage in Dahl rats. Kidney Int 26:137-143.
16. Rappaport J, Hanss B, Kopp JB, Copeland TD, Bruggeman LA, Coffman TM, and Klotman PE (1995). Transport of phosphorothioate oligonucleotides in kidney: Implications for molecular therapy. Kidney Int 47:1462-1469.
17. Razzaque MS and Taguchi T (1997). Collagen-binding heat shock protein (HSP) 47 expression in anti-thymocyte serum (ATS)-induced glomerulonephritis. J Pathol 183:24-29.
18. Saga S, Nagata K, Chen WT, and Yamada KM (1987). pH-dependent function, purification, and intracellular location of a major collagen-binding glycoprotein. J Cell Biol 105:517-527.
19. Satoh M, Hirayoshi K, Yoshida S, Hosokawa N, and Nagata K (1996). Intracellular interaction of collagen-specific stress protein HSP47 with newly synthesized procollagen. J Cell Biol 133:469-483.
20. Sauk JJ, Smith T, Norris K, and Ferreira L (1994). HSP47 and the translation-translocation machinery cooperate in the production of α1(1) chains of type I procollagen. J Biol Chem 269:3941-3946.
21. Striker LM, Killen PD, Chi E, and Striker GE (1984). The composition of glomerulosclerosis. I. Studies in focal sclerosis, crescentic glomerulonephritis, and membranoproliferative glomerulonephritis. Lab Invest 51:181-192.
22. Sunamoto M, Kuze K, Iehara N, Takeoka H, Nagata K, Kita T, and Doi T (in press, 1998). Expression of heat shock protein 47 is increased in remnant kidney and correlates with disease progression. Int J Exp Pathol.
23. Takechi H, Hirayoshi K, Nakai A, Kudo H, Saga S, and Nagata K (1992). Molecular cloning of a mouse 47-kDa heat-shock protein (HSP47), a collagen-binding stress protein, and its expression during the differentiation of F9 teratocarcinoma cells. Eur J Biochem 206:323-329.