메뉴 건너뛰기




Volumn 21, Issue 2, 2007, Pages 141-146

Antioxidant gene therapeutic approaches to normal tissue radioprotection and tumor radiosensitization

Author keywords

Antioxidant pool; MnSOD plasmid liposomes; Radiosensitization; Redox balance; Review

Indexed keywords

ADRENERGIC RECEPTOR STIMULATING AGENT; AMIFOSTINE; ANTIBIOTIC AGENT; ANTIOXIDANT; BETAFECTIN; CARBOPLATIN; CISPLATIN; COLONY STIMULATING FACTOR 1; CYTOKINE; DOCETAXEL; ERYTHROPOIETIN; ETOPOSIDE; GLUTAMINE; GLUTATHIONE; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; MACROPHAGE ACTIVATING FACTOR; MANGANESE SUPEROXIDE DISMUTASE; PALIFERMIN; PENTOXIFYLLINE; PILOCARPINE; PLATINUM COMPLEX; TAXANE DERIVATIVE; RADIOPROTECTIVE AGENT;

EID: 34047234150     PISSN: 0258851X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (61)

References (73)
  • 2
    • 0018749490 scopus 로고
    • Role of superoxide dismutase in cancer: A review
    • Oberley LW and Buettner GR: Role of superoxide dismutase in cancer: a review. Cancer Res 39: 1141-1149, 1979.
    • (1979) Cancer Res , vol.39 , pp. 1141-1149
    • Oberley, L.W.1    Buettner, G.R.2
  • 3
    • 0002030285 scopus 로고
    • Free radicals, cancer, and aging
    • In: Johnson JE Jr., Walford R, Harmon D, Miquel J (eds). Alan R. Liss, Inc
    • Oberley LW and Oberley TD: Free radicals, cancer, and aging. In: Free radicals, aging, and degenerative diseases. Johnson JE Jr., Walford R, Harmon D, Miquel J (eds). Alan R. Liss, Inc., pp. 325-381, 1986.
    • (1986) Free Radicals, Aging, and Degenerative Diseases , pp. 325-381
    • Oberley, L.W.1    Oberley, T.D.2
  • 4
    • 0034660880 scopus 로고    scopus 로고
    • The role of cellular glutathione peroxidase redox regulation in the suppression of tumor cell growth by manganese superoxide dismutase
    • Li S, Yan T, Yang J-Q, Oberley TD and Oberley LW: The role of cellular glutathione peroxidase redox regulation in the suppression of tumor cell growth by manganese superoxide dismutase. Cancer Res 60: 3927-3939, 2000.
    • (2000) Cancer Res , vol.60 , pp. 3927-3939
    • Li, S.1    Yan, T.2    Yang, J.-Q.3    Oberley, T.D.4    Oberley, L.W.5
  • 6
    • 0028012335 scopus 로고
    • Glutathione peroxidase compensates for the hypersensitivity of Cu, Zn-superoxide dismutase overproducers to oxidant stress
    • Amstad P, Moret R and Cerutti P: Glutathione peroxidase compensates for the hypersensitivity of Cu, Zn-superoxide dismutase overproducers to oxidant stress. J Biol Chem 269(3): 1606-1609, 1994.
    • (1994) J Biol Chem , vol.269 , Issue.3 , pp. 1606-1609
    • Amstad, P.1    Moret, R.2    Cerutti, P.3
  • 7
    • 0028945710 scopus 로고
    • Transfection with human copper zinc superoxide dismutase induces bi-directional alterations in other antioxidant enzymes, proteins, growth factor response, and paraquat resistance
    • Kelner MJ, Bagnell R, Montoya M, Estes L, Uglik SF and Cerutti P: Transfection with human copper zinc superoxide dismutase induces bi-directional alterations in other antioxidant enzymes, proteins, growth factor response, and paraquat resistance. Free Radic Biol Med 18(3): 497-506, 1995.
    • (1995) Free Radic Biol Med , vol.18 , Issue.3 , pp. 497-506
    • Kelner, M.J.1    Bagnell, R.2    Montoya, M.3    Estes, L.4    Uglik, S.F.5    Cerutti, P.6
  • 8
    • 0025940313 scopus 로고
    • The balance between Cu, Zn-superoxide dismutase and catalase affects the sensitivity of mouse epidermal cells to oxidative stress
    • Amstad P, Peskin A, Shah G, Mirault M-E, Moret R, Zbinden I and Cerutti P: The balance between Cu, Zn-superoxide dismutase and catalase affects the sensitivity of mouse epidermal cells to oxidative stress. Biochem 30: 9305-9313, 1991.
    • (1991) Biochem , vol.30 , pp. 9305-9313
    • Amstad, P.1    Peskin, A.2    Shah, G.3    Mirault, M.-E.4    Moret, R.5    Zbinden, I.6    Cerutti, P.7
  • 9
    • 0024461627 scopus 로고
    • Translocation and enhancement of phosphotransferase activity of protein kinase C following exposure in mouse epidermal cells to oxidants
    • Larsson R and Cerutti P: Translocation and enhancement of phosphotransferase activity of protein kinase C following exposure in mouse epidermal cells to oxidants. Cancer Res 49(20): 5627-5632, 1989.
    • (1989) Cancer Res , vol.49 , Issue.20 , pp. 5627-5632
    • Larsson, R.1    Cerutti, P.2
  • 10
    • 0029875833 scopus 로고    scopus 로고
    • High glucose induces antioxidant enzymes in human endothelial cells in culture. Evidence linking hyperglycemia and oxidative stress
    • Ceriello A, dello Russo P, Amstad P and Cerutti P: High glucose induces antioxidant enzymes in human endothelial cells in culture. Evidence linking hyperglycemia and oxidative stress. Diabetes 45(4): 471-477, 1996.
    • (1996) Diabetes , vol.45 , Issue.4 , pp. 471-477
    • Ceriello, A.1    dello Russo, P.2    Amstad, P.3    Cerutti, P.4
  • 11
    • 0029170274 scopus 로고
    • The roles of hydrogen peroxide and superoxide as messengers in the activation of transcription factor NF-κB
    • Schmidt KN, Amstad P and Cerutti P: The roles of hydrogen peroxide and superoxide as messengers in the activation of transcription factor NF-κB. Chem Biol 2: 13-22, 1995.
    • (1995) Chem Biol , vol.2 , pp. 13-22
    • Schmidt, K.N.1    Amstad, P.2    Cerutti, P.3
  • 12
    • 0032605109 scopus 로고    scopus 로고
    • Manganese superoxide dismutase (MnSOD) plasmid/liposome pulmonary radioprotective gene therapy: Modulation of irradiation-induced mRNA for IL-1, TNF-α, and TGF-β correlates with delay of organizing alveolitis/fibrosis
    • Epperly MW, Travis EL, Sikora C and Greenberger JS: Manganese superoxide dismutase (MnSOD) plasmid/liposome pulmonary radioprotective gene therapy: modulation of irradiation-induced mRNA for IL-1, TNF-α, and TGF-β correlates with delay of organizing alveolitis/fibrosis. Biol Blood Marrow Transplant 5: 204-214, 1999.
    • (1999) Biol Blood Marrow Transplant , vol.5 , pp. 204-214
    • Epperly, M.W.1    Travis, E.L.2    Sikora, C.3    Greenberger, J.S.4
  • 13
    • 0035144389 scopus 로고    scopus 로고
    • Modulation of radiation-induced cytokine elevation associated with esophagitis and esophageal stricture by manganese superoxide dismutase-plasmid/liposome (SOD-PL) gene therapy
    • Epperly MW, Gretton JA, DeFilippi SJ, Sikora CA, Liggitt D, Koe G and Greenberger JS: Modulation of radiation-induced cytokine elevation associated with esophagitis and esophageal stricture by manganese superoxide dismutase-plasmid/liposome (SOD-PL) gene therapy. Radiat Res 155: 2-14, 2001.
    • (2001) Radiat Res , vol.155 , pp. 2-14
    • Epperly, M.W.1    Gretton, J.A.2    DeFilippi, S.J.3    Sikora, C.A.4    Liggitt, D.5    Koe, G.6    Greenberger, J.S.7
  • 14
    • 0033920418 scopus 로고    scopus 로고
    • Plasmid/liposome transfer of the human manganese superoxide dismutase (MnSOD) transgene prevents ionizing irradiation-induced apoptosis in human esophageal organ explant culture
    • Epperly MW, Sikora C, Defilippi S, Bray J, Koe G, Liggitt D, Luketich JD and Greenberger JS: Plasmid/liposome transfer of the human manganese superoxide dismutase (MnSOD) transgene prevents ionizing irradiation-induced apoptosis in human esophageal organ explant culture. Int J Cancer (Radiat Oncol Invest) 90(3): 128-137, 2000.
    • (2000) Int J Cancer (Radiat Oncol Invest) , vol.90 , Issue.3 , pp. 128-137
    • Epperly, M.W.1    Sikora, C.2    Defilippi, S.3    Bray, J.4    Koe, G.5    Liggitt, D.6    Luketich, J.D.7    Greenberger, J.S.8
  • 15
    • 0033398125 scopus 로고    scopus 로고
    • Overexpression of the human MnSOD transgene in subclones of murine hematopoietic progenitor cell line 32D cl 3 decreases irradiation-induced apoptosis but does not alter G2/M or G1/S phase cell cycle arrest
    • Epperly MW, Bray JA, Esocobar P, Bigbee WL, Watkins S and Greenberger JS: Overexpression of the human MnSOD transgene in subclones of murine hematopoietic progenitor cell line 32D cl 3 decreases irradiation-induced apoptosis but does not alter G2/M or G1/S phase cell cycle arrest. Radiat Oncol Invest Clin Basic Res 7: 331-342, 1999.
    • (1999) Radiat Oncol Invest Clin Basic Res , vol.7 , pp. 331-342
    • Epperly, M.W.1    Bray, J.A.2    Esocobar, P.3    Bigbee, W.L.4    Watkins, S.5    Greenberger, J.S.6
  • 16
    • 0036249831 scopus 로고    scopus 로고
    • Manganese superoxide dismutase (SOD2) inhibits radiation-induced apoptosis by stabilization of the mitochondrial membrane
    • Epperly MW, Sikora C, Defilippi S, Gretton J, Zhan Q, Kufe DW and Greenberger JS: Manganese superoxide dismutase (SOD2) inhibits radiation-induced apoptosis by stabilization of the mitochondrial membrane. Radiat Res 157(5): 568-577, 2002.
    • (2002) Radiat Res , vol.157 , Issue.5 , pp. 568-577
    • Epperly, M.W.1    Sikora, C.2    Defilippi, S.3    Gretton, J.4    Zhan, Q.5    Kufe, D.W.6    Greenberger, J.S.7
  • 18
    • 0034660880 scopus 로고    scopus 로고
    • The role of cellular glutathione peroxidase redox regulation in the suppression of tumor cell growth by manganese superoxide dismutase
    • Li S, Yan T, Yang JQ, Oberley TD and Oberley LW: The role of cellular glutathione peroxidase redox regulation in the suppression of tumor cell growth by manganese superoxide dismutase. Cancer Res 60: 3927-3939, 2000.
    • (2000) Cancer Res , vol.60 , pp. 3927-3939
    • Li, S.1    Yan, T.2    Yang, J.Q.3    Oberley, T.D.4    Oberley, L.W.5
  • 19
    • 0348226533 scopus 로고    scopus 로고
    • Mitochondrial localization of superoxide dismutase is required for decreasing irradiation-induced cellular damage
    • Epperly MW, Gretton JE, Sikora CA, Jefferson M, Bernarding M, Nie S and Greenberger JS: Mitochondrial localization of superoxide dismutase is required for decreasing irradiation-induced cellular damage. Radiat Res 160: 568-578, 2003.
    • (2003) Radiat Res , vol.160 , pp. 568-578
    • Epperly, M.W.1    Gretton, J.E.2    Sikora, C.A.3    Jefferson, M.4    Bernarding, M.5    Nie, S.6    Greenberger, J.S.7
  • 20
    • 0038449134 scopus 로고    scopus 로고
    • Overexpression of the transgene for manganese superoxide dismutase (MnSOD) in 32D cl 3 cells prevents apoptosis induction by TNF-α, IL-3 withdrawal and ionizing irradiation
    • Epperly MW, Bernarding M, Gretton J, Jefferson M, Nie S and Greenberger JS: Overexpression of the transgene for manganese superoxide dismutase (MnSOD) in 32D cl 3 cells prevents apoptosis induction by TNF-α, IL-3 withdrawal and ionizing irradiation. Exp Hematol 31(6): 465-474, 2003.
    • (2003) Exp Hematol , vol.31 , Issue.6 , pp. 465-474
    • Epperly, M.W.1    Bernarding, M.2    Gretton, J.3    Jefferson, M.4    Nie, S.5    Greenberger, J.S.6
  • 21
    • 0034131278 scopus 로고    scopus 로고
    • Intratracheal injection of manganese superoxide dismutase (MnSOD) plasmid/liposomes protects normal lung but not orthotopic tumors from irradiation
    • Epperly MW, Defilippi S, Sikora C, Gretton J, Kalend K and Greenberger JS: Intratracheal injection of manganese superoxide dismutase (MnSOD) plasmid/liposomes protects normal lung but not orthotopic tumors from irradiation. Gene Ther 7(12): 1011-1018, 2000.
    • (2000) Gene Ther , vol.7 , Issue.12 , pp. 1011-1018
    • Epperly, M.W.1    Defilippi, S.2    Sikora, C.3    Gretton, J.4    Kalend, K.5    Greenberger, J.S.6
  • 22
    • 0037242972 scopus 로고    scopus 로고
    • Manganese superoxide dismutase-plasmid/liposome (MnSOD-PL) intratracheal gene therapy reduction of irradiation-induced inflammatory cytokines does not protect orthotopic Lewis lung carcinomas
    • Guo HL, Epperly MW, Bernarding M, Nie S, Gretton J, Jefferson M and Greenberger JS: Manganese superoxide dismutase-plasmid/liposome (MnSOD-PL) intratracheal gene therapy reduction of irradiation-induced inflammatory cytokines does not protect orthotopic Lewis lung carcinomas. In Vivo 17: 13-22, 2003.
    • (2003) In Vivo , vol.17 , pp. 13-22
    • Guo, H.L.1    Epperly, M.W.2    Bernarding, M.3    Nie, S.4    Gretton, J.5    Jefferson, M.6    Greenberger, J.S.7
  • 24
    • 0034656192 scopus 로고    scopus 로고
    • Oxygen free radicals mediate the induction of manganese superoxide dismutase gene expression by TNF-α
    • Liu R, Buettner GR and Oberley LW: Oxygen free radicals mediate the induction of manganese superoxide dismutase gene expression by TNF-α. Free Radic Biol Med 28(8): 1197-1205, 2000.
    • (2000) Free Radic Biol Med , vol.28 , Issue.8 , pp. 1197-1205
    • Liu, R.1    Buettner, G.R.2    Oberley, L.W.3
  • 25
    • 0035871683 scopus 로고    scopus 로고
    • Phospholipid hydroperoxide glutathione peroxidase protects against singlet oxygen-induced cell damage of photodynamic therapy
    • Wang HP, Qian SY, Schafer FQ, Domann FE, Oberley LW and Buettner GR: Phospholipid hydroperoxide glutathione peroxidase protects against singlet oxygen-induced cell damage of photodynamic therapy. Free Radic Biol Med 30(8): 825-835, 2001.
    • (2001) Free Radic Biol Med , vol.30 , Issue.8 , pp. 825-835
    • Wang, H.P.1    Qian, S.Y.2    Schafer, F.Q.3    Domann, F.E.4    Oberley, L.W.5    Buettner, G.R.6
  • 26
    • 0035878875 scopus 로고    scopus 로고
    • Redox modulation of the pro-fibrogenic mediator plasminogen activator inhibitor-1 following ionizing irradiation
    • Zhao W, Spitz DR, Oberley LW and Robbins MEC: Redox modulation of the pro-fibrogenic mediator plasminogen activator inhibitor-1 following ionizing irradiation. Cancer Res 61: 5537-5543, 2001.
    • (2001) Cancer Res , vol.61 , pp. 5537-5543
    • Zhao, W.1    Spitz, D.R.2    Oberley, L.W.3    Robbins, M.E.C.4
  • 27
    • 0033460221 scopus 로고    scopus 로고
    • Expression of superoxide dismutases, catalase, and glutathione peroxidase in glioma cells
    • Zhong W, Yan T, Lim R and Oberley LW: Expression of superoxide dismutases, catalase, and glutathione peroxidase in glioma cells. Free Radic Biol Med 27(11/12): 1334-1345, 1999.
    • (1999) Free Radic Biol Med , vol.27 , Issue.11-12 , pp. 1334-1345
    • Zhong, W.1    Yan, T.2    Lim, R.3    Oberley, L.W.4
  • 28
    • 0034660880 scopus 로고    scopus 로고
    • The role of cellular glutathione peroxidase redox regulation in the suppression of tumor cell growth by manganese superoxide dismutase
    • Li S, Yan T, Yan J-Q, Oberley TD and Oberley LW: The role of cellular glutathione peroxidase redox regulation in the suppression of tumor cell growth by manganese superoxide dismutase. Cancer Res 60: 3927-3939, 2000.
    • (2000) Cancer Res , vol.60 , pp. 3927-3939
    • Li, S.1    Yan, T.2    Yan, J.-Q.3    Oberley, T.D.4    Oberley, L.W.5
  • 29
    • 0036170568 scopus 로고    scopus 로고
    • Overexpression of copper zinc superoxide dismutase suppresses human glioma cell growth
    • Zhang Y, Zhao W, Zhang HJ, Domann FE and Oberley LW: Overexpression of copper zinc superoxide dismutase suppresses human glioma cell growth. Cancer Res 62: 1205-1212, 2002.
    • (2002) Cancer Res , vol.62 , pp. 1205-1212
    • Zhang, Y.1    Zhao, W.2    Zhang, H.J.3    Domann, F.E.4    Oberley, L.W.5
  • 30
    • 0035254175 scopus 로고    scopus 로고
    • Genes regulated in human breast cancer cells overexpressing manganese-containing superoxide dismutase
    • Li Z, Khaletskly A, Wang J, Wong JYC, Oberley LW and Li JJ: Genes regulated in human breast cancer cells overexpressing manganese-containing superoxide dismutase. Free Radic Biol Med 30(3): 260-267, 2001.
    • (2001) Free Radic Biol Med , vol.30 , Issue.3 , pp. 260-267
    • Li, Z.1    Khaletskly, A.2    Wang, J.3    Wong, J.Y.C.4    Oberley, L.W.5    Li, J.J.6
  • 31
    • 0037674062 scopus 로고    scopus 로고
    • Phase II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neck
    • Cohen EEW, Rosen F, Stadler WM, Recant W, Stenson K, Huo D and Vokes EE: Phase II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neck. J Clin Oncol 21(10): 1980-1987, 2003.
    • (2003) J Clin Oncol , vol.21 , Issue.10 , pp. 1980-1987
    • Cohen, E.E.W.1    Rosen, F.2    Stadler, W.M.3    Recant, W.4    Stenson, K.5    Huo, D.6    Vokes, E.E.7
  • 32
    • 1442329033 scopus 로고    scopus 로고
    • Acute lung injury in lung cancer patients treated with ZD1839 and bleomycin-induced pulmonary fibrosis in mice
    • Kanemura T, Suzuki H, Aoshiba K, Yokohori N and Nagai A: Acute lung injury in lung cancer patients treated with ZD1839 and bleomycin-induced pulmonary fibrosis in mice. Proc Am Soc Clin Oncol 22: 652, 2003.
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 652
    • Kanemura, T.1    Suzuki, H.2    Aoshiba, K.3    Yokohori, N.4    Nagai, A.5
  • 33
    • 0037531643 scopus 로고    scopus 로고
    • Targeting epidermal growth factor receptor: Novel therapeutics in the management of cancer
    • Khalil MY, Grandis JR and Shin DM: Targeting epidermal growth factor receptor: novel therapeutics in the management of cancer. Expert Rev Anticancer Therapy 3(3): 367-380, 2003.
    • (2003) Expert Rev Anticancer Therapy , vol.3 , Issue.3 , pp. 367-380
    • Khalil, M.Y.1    Grandis, J.R.2    Shin, D.M.3
  • 34
    • 0033531247 scopus 로고    scopus 로고
    • Mutations in the promoter reveal a cause for the reduced expression of the human manganese superoxide dismutase gene in cancer cells
    • Xu Y, Krishnan A, Wan SX, Majima H, Yeh C-C, Ludewig G, Kasarskis EJ and St. Clair DK: Mutations in the promoter reveal a cause for the reduced expression of the human manganese superoxide dismutase gene in cancer cells. Oncogene 18: 93-102, 1999.
    • (1999) Oncogene , vol.18 , pp. 93-102
    • Xu, Y.1    Krishnan, A.2    Wan, S.X.3    Majima, H.4    Yeh, C.-C.5    Ludewig, G.6    Kasarskis, E.J.7    St. Clair, D.K.8
  • 35
    • 0027093827 scopus 로고
    • Suppression of radiation-induced neoplastic transformation by overexpression of mitochondrial superoxide dismutase
    • St. Clair DK, Wan XS, Oberley TD, Muse KE and St. Clair WH: Suppression of radiation-induced neoplastic transformation by overexpression of mitochondrial superoxide dismutase. Molec Carcinogenesis 6: 238-242, 1992.
    • (1992) Molec Carcinogenesis , vol.6 , pp. 238-242
    • St. Clair, D.K.1    Wan, X.S.2    Oberley, T.D.3    Muse, K.E.4    St. Clair, W.H.5
  • 36
    • 0031806483 scopus 로고    scopus 로고
    • Calcium-dependent stimulation of mitogen-activated protein kinase activity in A431 cells by low doses of ionizing radiation
    • Kavanagh BD, Dent P, Schmidt-Ullrich RK, Chen P and Mikkelsen RB: Calcium-dependent stimulation of mitogen-activated protein kinase activity in A431 cells by low doses of ionizing radiation. Radiat Res 149(6): 579-587, 1998.
    • (1998) Radiat Res , vol.149 , Issue.6 , pp. 579-587
    • Kavanagh, B.D.1    Dent, P.2    Schmidt-Ullrich, R.K.3    Chen, P.4    Mikkelsen, R.B.5
  • 37
    • 29944435931 scopus 로고    scopus 로고
    • The switch from DNA repair to apoptosis: Discovery of a refractory period for radiation-induced EGFR-MAPK signaling following irradiation
    • Hagan MP, Yacoub A and Dent P: The switch from DNA repair to apoptosis: Discovery of a refractory period for radiation-induced EGFR-MAPK signaling following irradiation. IJROBP 57(2): Suppl #1050, 2003.
    • (2003) IJROBP , vol.57 , Issue.2 SUPPL. 1050
    • Hagan, M.P.1    Yacoub, A.2    Dent, P.3
  • 38
    • 0032575135 scopus 로고    scopus 로고
    • Inhibition of the mitogen activated protein (MAP) kinase cascade potentiates cell killing by low dose ionizing irradiation in A431 human squamous carcinoma cells
    • Carter S, Auer KL, Reardon DB, Birrer M, Fisher PB, Valerie K, Schmidt-Ullrich R, Mikkelsen R and Dent P: Inhibition of the mitogen activated protein (MAP) kinase cascade potentiates cell killing by low dose ionizing irradiation in A431 human squamous carcinoma cells. Oncogene 16: 2787-2796, 1998.
    • (1998) Oncogene , vol.16 , pp. 2787-2796
    • Carter, S.1    Auer, K.L.2    Reardon, D.B.3    Birrer, M.4    Fisher, P.B.5    Valerie, K.6    Schmidt-Ullrich, R.7    Mikkelsen, R.8    Dent, P.9
  • 40
    • 0041856141 scopus 로고    scopus 로고
    • Induction of glia maturation factor-B in proximal tubular cells leads to vulnerability to oxidative injury through the p38 pathway and changes in antioxidant enzyme activities
    • Kaimori J, Takenaka M, Nakajima H, Hamano T, Horio M, Sugaya T, Ito T, Hori M, Okubo K and Imai E: Induction of glia maturation factor-B in proximal tubular cells leads to vulnerability to oxidative injury through the p38 pathway and changes in antioxidant enzyme activities. J Biol Chem 278(35): 33519-33527, 2003.
    • (2003) J Biol Chem , vol.278 , Issue.35 , pp. 33519-33527
    • Kaimori, J.1    Takenaka, M.2    Nakajima, H.3    Hamano, T.4    Horio, M.5    Sugaya, T.6    Ito, T.7    Hori, M.8    Okubo, K.9    Imai, E.10
  • 41
    • 0037245709 scopus 로고    scopus 로고
    • Oxidative stress-induced apoptosis in dividing fibroblasts involves activation of p38 MAP kinase and overexpression of Bax: Resistance of quiescent cells to oxidative stress
    • Naderi J, Hung M and Pandey S: Oxidative stress-induced apoptosis in dividing fibroblasts involves activation of p38 MAP kinase and overexpression of Bax: Resistance of quiescent cells to oxidative stress. Apoptosis 8: 91-100, 2003.
    • (2003) Apoptosis , vol.8 , pp. 91-100
    • Naderi, J.1    Hung, M.2    Pandey, S.3
  • 42
    • 0034141938 scopus 로고    scopus 로고
    • Oxidative stress causes mucin synthesis via transactivation of epidermal growth factor receptor: Role of neutrophils
    • Takeyanna K, Dabbagh K, Shim JJ, Dan-Pick T, Ueki IF and Nadel JA: Oxidative stress causes mucin synthesis via transactivation of epidermal growth factor receptor: role of neutrophils. J Immunol 164: 1546-1552, 2000.
    • (2000) J Immunol , vol.164 , pp. 1546-1552
    • Takeyanna, K.1    Dabbagh, K.2    Shim, J.J.3    Dan-Pick, T.4    Ueki, I.F.5    Nadel, J.A.6
  • 43
    • 0037338423 scopus 로고    scopus 로고
    • Prevention of irradiation-induced oral cavity mucositis by plasmid /liposome delivery of the human manganese superoxide dismutase (MnSOD) transgene
    • Guo H, Seixas-Silva J, Epperly MW, Gretton JE, Shin DM, Bar-Sagi D, Archer H and Greenberger JS: Prevention of irradiation-induced oral cavity mucositis by plasmid/liposome delivery of the human manganese superoxide dismutase (MnSOD) transgene. Radia Res 159: 361-370, 2003.
    • (2003) Radia Res , vol.159 , pp. 361-370
    • Guo, H.1    Seixas-Silva, J.2    Epperly, M.W.3    Gretton, J.E.4    Shin, D.M.5    Bar-Sagi, D.6    Archer, H.7    Greenberger, J.S.8
  • 45
    • 0031965432 scopus 로고    scopus 로고
    • Considerations in optimizing radiation therapy for non-small cell lung cancer
    • (International Symposium on Thoracic Malignancies)
    • Greenberger JS, Bahri S, Jett J, Belani C, Kalend A and Epperly MW: Considerations in optimizing radiation therapy for non-small cell lung cancer. (International Symposium on Thoracic Malignancies). Chest 113(1): 465-525, 1998.
    • (1998) Chest , vol.113 , Issue.1 , pp. 465-525
    • Greenberger, J.S.1    Bahri, S.2    Jett, J.3    Belani, C.4    Kalend, A.5    Epperly, M.W.6
  • 46
    • 0032503658 scopus 로고    scopus 로고
    • Redox gene therapy protects human 1B-3 lung epithelial cells against ionizing radiation-induced apoptosis
    • Zwacka RM, Dudus L, Epperly MW, Greenberger JS and Engelhardt JF: Redox gene therapy protects human 1B-3 lung epithelial cells against ionizing radiation-induced apoptosis. Human Gene Therapy 9: 1381-1386, 1998.
    • (1998) Human Gene Therapy , vol.9 , pp. 1381-1386
    • Zwacka, R.M.1    Dudus, L.2    Epperly, M.W.3    Greenberger, J.S.4    Engelhardt, J.F.5
  • 47
    • 0032888334 scopus 로고    scopus 로고
    • Prevention of irradiation-induced esophagitis by plasmid/liposome delivery of the human manganese superoxide dismutase (MnSOD) transgene
    • Stickle RL, Epperly MW, Klein E, Bray JA and Greenberger JS: Prevention of irradiation-induced esophagitis by plasmid/liposome delivery of the human manganese superoxide dismutase (MnSOD) transgene. Radiat Oncol Invest Clin Basic Res 7(6): 204-217, 1999.
    • (1999) Radiat Oncol Invest Clin Basic Res , vol.7 , Issue.6 , pp. 204-217
    • Stickle, R.L.1    Epperly, M.W.2    Klein, E.3    Bray, J.A.4    Greenberger, J.S.5
  • 49
    • 0033809159 scopus 로고    scopus 로고
    • Decreased pulmonary radiation resistance of manganese superoxide dismutase (MnS0D)-deficient mice is corrected by human manganese superoxide dismutase-plasmid/liposome (SOD2-PL) intratracheal gene therapy
    • Epperly MW, Epstein CJ, Travis EL and Greenberger JS: Decreased pulmonary radiation resistance of manganese superoxide dismutase (MnS0D)-deficient mice is corrected by human manganese superoxide dismutase-plasmid/liposome (SOD2-PL) intratracheal gene therapy. Radiation Res 154(4): 365-374, 2000.
    • (2000) Radiation Res , vol.154 , Issue.4 , pp. 365-374
    • Epperly, M.W.1    Epstein, C.J.2    Travis, E.L.3    Greenberger, J.S.4
  • 50
    • 0035916343 scopus 로고    scopus 로고
    • Overexpression of manganese superoxide dismutase (MnSOD) in whole lung or alveolar type II (AT-II) cells of MnSOD transgenic mice does not provide intrinsic lung irradiation protection
    • Epperly MW, Travis EL, Whitsett JA, Epstein CJ and Greenberger JS: Overexpression of manganese superoxide dismutase (MnSOD) in whole lung or alveolar type II (AT-II) cells of MnSOD transgenic mice does not provide intrinsic lung irradiation protection. Radiat Oncol Invest 96: 11-21, 2001.
    • (2001) Radiat Oncol Invest , vol.96 , pp. 11-21
    • Epperly, M.W.1    Travis, E.L.2    Whitsett, J.A.3    Epstein, C.J.4    Greenberger, J.S.5
  • 56
    • 0035370688 scopus 로고    scopus 로고
    • WR2721 before fractionated irradiation protects bone growth in rats better than fractionation alone
    • Damron TA, Margulies B, Biskup D and Spadaro JA: WR2721 before fractionated irradiation protects bone growth in rats better than fractionation alone. Int J Radiat Oncol Biol Phys 50(1): 479-483, 2001.
    • (2001) Int J Radiat Oncol Biol Phys , vol.50 , Issue.1 , pp. 479-483
    • Damron, T.A.1    Margulies, B.2    Biskup, D.3    Spadaro, J.A.4
  • 57
    • 0035370170 scopus 로고    scopus 로고
    • Acupuncture for piocarpine-resistant xerostomia following radiotherapy for head and neck malignancies
    • Johnstone PA, Peng YP, May BC, Inouye WS and Niemtzow RC: Acupuncture for piocarpine-resistant xerostomia following radiotherapy for head and neck malignancies. Int J Radiat Oncol Biol Phys 50(2): 353-357, 2001.
    • (2001) Int J Radiat Oncol Biol Phys , vol.50 , Issue.2 , pp. 353-357
    • Johnstone, P.A.1    Peng, Y.P.2    May, B.C.3    Inouye, W.S.4    Niemtzow, R.C.5
  • 59
    • 0346993594 scopus 로고    scopus 로고
    • Pentoxifylline in prevention of radiation-induced lung toxicity in patients with breast and lung cancer: A double-blind randomized trial
    • Ozturk B, Egehan I, Atavci S and Kitapci M: Pentoxifylline in prevention of radiation-induced lung toxicity in patients with breast and lung cancer: a double-blind randomized trial. Int J Radiat Oncol Biol Phys 58(1): 213-219, 2004.
    • (2004) Int J Radiat Oncol Biol Phys , vol.58 , Issue.1 , pp. 213-219
    • Ozturk, B.1    Egehan, I.2    Atavci, S.3    Kitapci, M.4
  • 60
    • 0032817960 scopus 로고    scopus 로고
    • Preservation of the rat parotid gland function after radiation by prophylactic pilocarpine treatment: Radiation dose dependency and compensatory mechanisms
    • Roesink JM, Konings AWT, Terhaard CHJ, Battermann JJ, Kampinga HH and Coppes RP: Preservation of the rat parotid gland function after radiation by prophylactic pilocarpine treatment: radiation dose dependency and compensatory mechanisms. Int J Radiat Oncol Biol Phys 45(2): 483-489, 1999.
    • (1999) Int J Radiat Oncol Biol Phys , vol.45 , Issue.2 , pp. 483-489
    • Roesink, J.M.1    Konings, A.W.T.2    Terhaard, C.H.J.3    Battermann, J.J.4    Kampinga, H.H.5    Coppes, R.P.6
  • 62
    • 0346363399 scopus 로고    scopus 로고
    • Zinc sulfate in the prevention of radiation-induced oropharyngeal mucositis: A prospective, placebo-controlled, randomized study
    • Ertekin MV, Koc M, Karslioglu I and Sezen O: Zinc sulfate in the prevention of radiation-induced oropharyngeal mucositis: A prospective, placebo-controlled, randomized study. Int J Radiat Oncol Biol Phys 58(1): 167-174, 2004.
    • (2004) Int J Radiat Oncol Biol Phys , vol.58 , Issue.1 , pp. 167-174
    • Ertekin, M.V.1    Koc, M.2    Karslioglu, I.3    Sezen, O.4
  • 68
    • 0035879299 scopus 로고    scopus 로고
    • High dose intra-arterial cisplatin boost with hyperfractionated radiation therapy for advanced squamous cell carcinoma of the head and neck
    • Regine WF, Valentino J, Arnold SM, Haydon RC, Sloan D, Kenady D, Strottmann J, Pulmano C and Mohiuddin M: High dose intra-arterial cisplatin boost with hyperfractionated radiation therapy for advanced squamous cell carcinoma of the head and neck. J Clin Oncol 19(14): 333-3339, 2001.
    • (2001) J Clin Oncol , vol.19 , Issue.14 , pp. 333-3339
    • Regine, W.F.1    Valentino, J.2    Arnold, S.M.3    Haydon, R.C.4    Sloan, D.5    Kenady, D.6    Strottmann, J.7    Pulmano, C.8    Mohiuddin, M.9
  • 69
    • 0035859006 scopus 로고    scopus 로고
    • WR2721 (WR2721) restores transcriptional activity of specific p53 mutant proteins in a yeast functional assay
    • Maurici D, Monti P, Campomenosi P, North S, Frebourg T, Fronza G and Hainaut P: WR2721 (WR2721) restores transcriptional activity of specific p53 mutant proteins in a yeast functional assay. Oncogene 20: 3533-3540, 2001.
    • (2001) Oncogene , vol.20 , pp. 3533-3540
    • Maurici, D.1    Monti, P.2    Campomenosi, P.3    North, S.4    Frebourg, T.5    Fronza, G.6    Hainaut, P.7
  • 70
    • 0033982779 scopus 로고    scopus 로고
    • Granulocyte macrophage-colony stimulating factor (GM-CSF) and sucralfate in prevention of radiation-induced mucositis: A prospective randomized study
    • Makkonen TA, Minn H, Jekunen A, Vilja P, Tuominen J and Joensuu H: Granulocyte macrophage-colony stimulating factor (GM-CSF) and sucralfate in prevention of radiation-induced mucositis: a prospective randomized study. Int J Radiat Oncol Biol Phys 46(3): 525-534, 2000.
    • (2000) Int J Radiat Oncol Biol Phys , vol.46 , Issue.3 , pp. 525-534
    • Makkonen, T.A.1    Minn, H.2    Jekunen, A.3    Vilja, P.4    Tuominen, J.5    Joensuu, H.6
  • 71
    • 0345732516 scopus 로고    scopus 로고
    • Evaluation of salivary gland function after treatment of head-and-neck tumors with intensity-modulated radiotherapy by quantitative pertechnetate scintigraphy
    • Munter MW, Karger CP, Hoffner SG, Hof H, Thilmann C, Rudat V, Nill S, Wannenmacher M and Debus J: Evaluation of salivary gland function after treatment of head-and-neck tumors with intensity-modulated radiotherapy by quantitative pertechnetate scintigraphy. Int J Radiat Oncol Biol Phys 58(1): 175-184, 2004.
    • (2004) Int J Radiat Oncol Biol Phys , vol.58 , Issue.1 , pp. 175-184
    • Munter, M.W.1    Karger, C.P.2    Hoffner, S.G.3    Hof, H.4    Thilmann, C.5    Rudat, V.6    Nill, S.7    Wannenmacher, M.8    Debus, J.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.