-
1
-
-
0141819138
-
The protein C pathway
-
Esmon, C. T. (2003) The protein C pathway, Chest 124, 26S-32S.
-
(2003)
Chest
, vol.124
-
-
Esmon, C.T.1
-
2
-
-
0242723866
-
-
Hoffman, R, Benz, E. J, Shattil, S. J, Furie, B, Cohen, H. J, Silberstein, L. E, and McGlave, P, Eds, pp, Churchill Livingstone, New York
-
Esmon, C. T. (2000) In Hematology. Basic Principles and Practice (Hoffman, R., Benz, E. J., Shattil, S. J., Furie, B., Cohen, H. J., Silberstein, L. E., and McGlave, P., Eds.) pp 1714-1824, Churchill Livingstone, New York.
-
(2000)
Hematology. Basic Principles and Practice
, pp. 1714-1824
-
-
Esmon, C.T.1
-
3
-
-
0029112841
-
Thrombomodulin as a model of molecular mechanisms that modulate protease specificity and function at the vessel surface
-
Esmon, C. T. (1995) Thrombomodulin as a model of molecular mechanisms that modulate protease specificity and function at the vessel surface, FASEB J. 9, 946-955.
-
(1995)
FASEB J
, vol.9
, pp. 946-955
-
-
Esmon, C.T.1
-
4
-
-
0034732094
-
Structural basis for the anticoagulant activity of the thrombin-thrombomodulin complex
-
Fuentes-Prior, P., Iwanaga, Y., Huber, R., Pagila, R., Rumennik, G., Seto, M., Morser, J., Light, D. R., and Bode, W. (2000) Structural basis for the anticoagulant activity of the thrombin-thrombomodulin complex, Nature 404, 518-525.
-
(2000)
Nature
, vol.404
, pp. 518-525
-
-
Fuentes-Prior, P.1
Iwanaga, Y.2
Huber, R.3
Pagila, R.4
Rumennik, G.5
Seto, M.6
Morser, J.7
Light, D.R.8
Bode, W.9
-
5
-
-
0037237639
-
Exosite-dependent regulation of the protein C anticoagulant pathway
-
Rezaie, A. R. (2003) Exosite-dependent regulation of the protein C anticoagulant pathway, Trends Cardiovasc. Med. 13, 8-15.
-
(2003)
Trends Cardiovasc. Med
, vol.13
, pp. 8-15
-
-
Rezaie, A.R.1
-
6
-
-
0031864780
-
Rapid activation of protein C by factor Xa and thrombin in the presence of polyanionic compounds
-
Rezaie, A. R. (1998) Rapid activation of protein C by factor Xa and thrombin in the presence of polyanionic compounds, Blood 91, 4572-4580.
-
(1998)
Blood
, vol.91
, pp. 4572-4580
-
-
Rezaie, A.R.1
-
7
-
-
0024435186
-
The activation of bovine protein C by factor Xa
-
Haley, P. E., Doyle, M. F., and Mann, K. G. (1989) The activation of bovine protein C by factor Xa, J. Biol. Chem. 264, 16303-16310.
-
(1989)
J. Biol. Chem
, vol.264
, pp. 16303-16310
-
-
Haley, P.E.1
Doyle, M.F.2
Mann, K.G.3
-
8
-
-
0034602993
-
Identification of basic residues in the heparin-binding exosite of factor Xa critical for heparin and factor Va binding
-
Rezaie, A. R. (2000) Identification of basic residues in the heparin-binding exosite of factor Xa critical for heparin and factor Va binding, J. Biol. Chem. 275, 3320-3327.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 3320-3327
-
-
Rezaie, A.R.1
-
9
-
-
0035968239
-
Structural and energetic characteristics of the heparin-binding site in antithrombotic protein C
-
Friedrich, U., Blom, A. M., Dahlback, B., and Villoutreix, B. O. (2001) Structural and energetic characteristics of the heparin-binding site in antithrombotic protein C, J. Biol. Chem. 276, 24122-24128.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 24122-24128
-
-
Friedrich, U.1
Blom, A.M.2
Dahlback, B.3
Villoutreix, B.O.4
-
11
-
-
0035971113
-
Hypersulfated low molecular weight heparin with reduced affinity for antithrombin acts as an anticoagulant by inhibiting intrinsic tenase and prothrombinase
-
Anderson, J. A. M., Fredenburgh, J. C., Stafford, A. R., Guo, Y. S., Hirsh, J., Ghazarossian, V., and Weitz, J. I. (2001) Hypersulfated low molecular weight heparin with reduced affinity for antithrombin acts as an anticoagulant by inhibiting intrinsic tenase and prothrombinase, J. Biol. Chem. 276, 9755-9761.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 9755-9761
-
-
Anderson, J.A.M.1
Fredenburgh, J.C.2
Stafford, A.R.3
Guo, Y.S.4
Hirsh, J.5
Ghazarossian, V.6
Weitz, J.I.7
-
12
-
-
0027078511
-
The function of calcium in protein C activation by thrombin and the thrombin-thrombomodulin complex can be distinguished by mutational analysis of protein C derivatives
-
Rezaie, A. R. and Esmon, C. T. (1992) The function of calcium in protein C activation by thrombin and the thrombin-thrombomodulin complex can be distinguished by mutational analysis of protein C derivatives, J. Biol. Chem. 267, 26104-26109.
-
(1992)
J. Biol. Chem
, vol.267
, pp. 26104-26109
-
-
Rezaie, A.R.1
Esmon, C.T.2
-
13
-
-
0242507439
-
Glycosaminoglycans bind factor Xa in a Ca2+-dependent fashion and modulate its catalytic activity
-
O'Brien, L. A., Stafford, A. R., Fredenburgh, J. C., and Weitz, J. I. (2003) Glycosaminoglycans bind factor Xa in a Ca2+-dependent fashion and modulate its catalytic activity, Biochemistry 42, 13091-13098.
-
(2003)
Biochemistry
, vol.42
, pp. 13091-13098
-
-
O'Brien, L.A.1
Stafford, A.R.2
Fredenburgh, J.C.3
Weitz, J.I.4
-
14
-
-
0017337301
-
A comparison of human prothrombin, factor IX (Christmas factor), factor X (Stuart factor), and protein S
-
Di Scipio, R. G., Hermodson, M. A., Yates, S. G., and Davie, E. W. (1977) A comparison of human prothrombin, factor IX (Christmas factor), factor X (Stuart factor), and protein S, Biochemistry 16, 698-706.
-
(1977)
Biochemistry
, vol.16
, pp. 698-706
-
-
Di Scipio, R.G.1
Hermodson, M.A.2
Yates, S.G.3
Davie, E.W.4
-
15
-
-
0018780186
-
Phospholipid-binding properties of bovine factor V and factor Va
-
Bloom, J. W., Nesheim, M. E., and Mann, K. G. (1979) Phospholipid-binding properties of bovine factor V and factor Va, Biochemistry 18, 4419-4425.
-
(1979)
Biochemistry
, vol.18
, pp. 4419-4425
-
-
Bloom, J.W.1
Nesheim, M.E.2
Mann, K.G.3
-
16
-
-
0026346977
-
Proteolytic formation of either of the two prothrombin activation intermediates results in formation of a hirugen-binding site
-
Liu, L. W., Ye, J., Johnson, A. E., and Esmon, C. T. (1991) Proteolytic formation of either of the two prothrombin activation intermediates results in formation of a hirugen-binding site, J. Biol. Chem. 266, 23632-23636.
-
(1991)
J. Biol. Chem
, vol.266
, pp. 23632-23636
-
-
Liu, L.W.1
Ye, J.2
Johnson, A.E.3
Esmon, C.T.4
-
17
-
-
17644420041
-
The affinity of protein C for the thrombin-thrombomodulin complex is determined in a primary way by active site-dependent interactions
-
Lu, G., Chhum, S., and Krishnaswamy, S. (2005) The affinity of protein C for the thrombin-thrombomodulin complex is determined in a primary way by active site-dependent interactions, J. Biol. Chem. 280, 15471-15478.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 15471-15478
-
-
Lu, G.1
Chhum, S.2
Krishnaswamy, S.3
-
18
-
-
14844331743
-
Thrombomodulin changes the molecular surface of interaction and the rate of complex formation between thrombin and protein C
-
Xu, H., Bush, L. A., Pineda, A. O., Caccia, S., and Di Cera, E. (2005) Thrombomodulin changes the molecular surface of interaction and the rate of complex formation between thrombin and protein C, J. Biol. Chem. 280, 7956-7961.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 7956-7961
-
-
Xu, H.1
Bush, L.A.2
Pineda, A.O.3
Caccia, S.4
Di Cera, E.5
-
19
-
-
0037443444
-
Gla domain-mutated human protein C exhibiting enhanced anticoagulant activity and increased phospholipid binding
-
Sun, Y. H., Shen, L., and Dahlback, B. (2003) Gla domain-mutated human protein C exhibiting enhanced anticoagulant activity and increased phospholipid binding, Blood 101, 2277-2284.
-
(2003)
Blood
, vol.101
, pp. 2277-2284
-
-
Sun, Y.H.1
Shen, L.2
Dahlback, B.3
-
20
-
-
0037076527
-
Contribution of basic residues of the 70-80-loop to heparin binding and anticoagulant function of activated protein C
-
Yang, L., Manithody, C., and Rezaie, A. R. (2002) Contribution of basic residues of the 70-80-loop to heparin binding and anticoagulant function of activated protein C, Biochemistry 41, 6149-6157.
-
(2002)
Biochemistry
, vol.41
, pp. 6149-6157
-
-
Yang, L.1
Manithody, C.2
Rezaie, A.R.3
-
21
-
-
0042346422
-
Proexosite-1 on prothrombin is a factor Va-dependent recognition site for the prothrombinase complex
-
Chen, L., Yang, L., and Rezaie, A. R. (2003) Proexosite-1 on prothrombin is a factor Va-dependent recognition site for the prothrombinase complex, J. Biol. Chem. 278, 27564-27569.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 27564-27569
-
-
Chen, L.1
Yang, L.2
Rezaie, A.R.3
-
22
-
-
0023720558
-
A combination of factor Xa and phosphatidylcholine-phosphatidylserine vesicles bypasses factor VIII in vivo
-
Giles, A. R., Mann, K. G., and Nesheim, M. E. (1988) A combination of factor Xa and phosphatidylcholine-phosphatidylserine vesicles bypasses factor VIII in vivo, Br. J. Haematol. 69, 491-497.
-
(1988)
Br. J. Haematol
, vol.69
, pp. 491-497
-
-
Giles, A.R.1
Mann, K.G.2
Nesheim, M.E.3
-
23
-
-
0021703070
-
Studies of factors V and VIII:C in an animal model of disseminated intravascular coagulation
-
Giles, A. R., Nesheim, M. E., and Mann, K. G. (1984) Studies of factors V and VIII:C in an animal model of disseminated intravascular coagulation, J. Clin. Invest. 74, 2219-2225.
-
(1984)
J. Clin. Invest
, vol.74
, pp. 2219-2225
-
-
Giles, A.R.1
Nesheim, M.E.2
Mann, K.G.3
-
24
-
-
0024337146
-
Activation of human protein C by blood coagulation factor Xa in the presence of anionic phospholipids. Enhancement by sulfated polysaccharides
-
Freyssinet, J. M., Wiesel, M. L., Grunebaum, L., Pereillo, J. M., Gauchy, J., Schuhler, S., Freund, G., and Cazenave, J. P. (1989) Activation of human protein C by blood coagulation factor Xa in the presence of anionic phospholipids. Enhancement by sulfated polysaccharides, Biochem. J. 261, 341-348.
-
(1989)
Biochem. J
, vol.261
, pp. 341-348
-
-
Freyssinet, J.M.1
Wiesel, M.L.2
Grunebaum, L.3
Pereillo, J.M.4
Gauchy, J.5
Schuhler, S.6
Freund, G.7
Cazenave, J.P.8
-
25
-
-
0034447287
-
Heparin-binding exosite of factor Xa
-
Rezaie, A. R. (2000) Heparin-binding exosite of factor Xa, Trends Cardiovasc. Med. 10, 333-338.
-
(2000)
Trends Cardiovasc. Med
, vol.10
, pp. 333-338
-
-
Rezaie, A.R.1
-
26
-
-
0026063331
-
Structure-function relationships of epidermal growth factor modules in vitamin K-dependent clotting factors
-
Stenflo, J. (1991) Structure-function relationships of epidermal growth factor modules in vitamin K-dependent clotting factors, Blood 78, 1637-1651.
-
(1991)
Blood
, vol.78
, pp. 1637-1651
-
-
Stenflo, J.1
-
27
-
-
0025816859
-
The association of coagulation factor Xa and factor Va
-
Pryzdial, E. L. G. and Mann, K. G. (1991) The association of coagulation factor Xa and factor Va, J. Biol. Chem. 266, 8969-8977.
-
(1991)
J. Biol. Chem
, vol.266
, pp. 8969-8977
-
-
Pryzdial, E.L.G.1
Mann, K.G.2
-
28
-
-
0035805579
-
Heparin enhances the specificity of antithrombin for thrombin and factor Xa independent of the reactive center loop sequence. Evidence for an exosite determinant of factor Xa specificity in heparin-activated antithrombin
-
Chuang, Y. J., Swanson, R., Raja, S. M., and Olson, S. T. (2001) Heparin enhances the specificity of antithrombin for thrombin and factor Xa independent of the reactive center loop sequence. Evidence for an exosite determinant of factor Xa specificity in heparin-activated antithrombin, J. Biol. Chem. 276, 14961-14971.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 14961-14971
-
-
Chuang, Y.J.1
Swanson, R.2
Raja, S.M.3
Olson, S.T.4
-
29
-
-
0029790055
-
The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex
-
Stearns-Kurosawa, D. J., Kurosawa, S., Mollica, J. S., Ferrell, G. L., and Esmon, C. T. (1996) The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex, Proc. Natl. Acad. Sci. U.S.A. 93, 10212-10216.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A
, vol.93
, pp. 10212-10216
-
-
Stearns-Kurosawa, D.J.1
Kurosawa, S.2
Mollica, J.S.3
Ferrell, G.L.4
Esmon, C.T.5
-
30
-
-
0030776168
-
Human protein C receptor is present primarily on endothelium of large blood vessels: Implications for the control of the protein C pathway
-
Laszik, Z., Mitro, A., Taylor, F. B., Jr., Ferrell, G., and Esmon, C. T. (1997) Human protein C receptor is present primarily on endothelium of large blood vessels: implications for the control of the protein C pathway, Circulation 96, 3633-3640.
-
(1997)
Circulation
, vol.96
, pp. 3633-3640
-
-
Laszik, Z.1
Mitro, A.2
Taylor Jr., F.B.3
Ferrell, G.4
Esmon, C.T.5
|