Glycosaminoglycans Bind Factor Xa in a Ca2+-Dependent Fashion and Modulate Its Catalytic Activity

Biochemistry

Volumn 42, Issue 44, 2003, Pages 13091-13098

  O'Brien, Lee A ^a   Stafford, Alan R ^a   Fredenburgh, James C ^a   Weitz, Jeffrey I ^a,b  

^a MCMASTER UNIVERSITY   (Canada)

^b HENDERSON RESEARCH CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ASSAYS; ATTENUATION; CALCIUM; CATALYSIS; FLUORESCENCE; TITRATION;

CHROMOGENIC SUBSTRATES;

PROTEINS;

BLOOD CLOTTING FACTOR 10A; FLUORESCEIN; GLYCOSAMINOGLYCAN; SULFATE;

ARTICLE; BINDING AFFINITY; BINDING KINETICS; BINDING SITE; CONFORMATIONAL TRANSITION; CORRELATION ANALYSIS; MODULATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN INTERACTION; TITRIMETRY;

1-CARBOXYGLUTAMIC ACID; AMINO ACID CHLOROMETHYL KETONES; BINDING SITES; CALCIUM; CATALYSIS; DERMATAN SULFATE; FACTOR VII; FACTOR XA; GLYCOSAMINOGLYCANS; HEPARIN; HEPARIN, LOW-MOLECULAR-WEIGHT; HUMANS; HYDROLYSIS; PROTEIN C; SUBSTRATE SPECIFICITY;

EID: 0242507439     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0345586     Document Type: Article

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