메뉴 건너뛰기




Volumn 204, Issue 2, 2007, Pages 759-766

Immunomodulatory properties of increased levels of liver X receptor β in peripheral blood mononuclear cells from multiple sclerosis patients

Author keywords

ABCA1; Cholesterol; HMGCoA reductase; IFN ; IL 4; LXR ; Lymphocytes; Multiple sclerosis

Indexed keywords

ABC TRANSPORTER A1; BETA ACTIN; CHOLESTEROL; COMPLEMENTARY DNA; CYTOKINE; GAMMA INTERFERON; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INTERLEUKIN 4 ANTIBODY; LIVER X RECEPTOR BETA; MESSENGER RNA;

EID: 34047190250     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2007.01.013     Document Type: Article
Times cited : (10)

References (24)
  • 2
    • 14844359386 scopus 로고    scopus 로고
    • Inactivation of liver X receptor β leads to adult-onset motor neuron degeneration in male mice
    • Andersson S., Gustafsson N., Warner M., and Gustafsson J. Inactivation of liver X receptor β leads to adult-onset motor neuron degeneration in male mice. PNAS 102 10 (2005) 3857-3862
    • (2005) PNAS , vol.102 , Issue.10 , pp. 3857-3862
    • Andersson, S.1    Gustafsson, N.2    Warner, M.3    Gustafsson, J.4
  • 3
    • 0037312805 scopus 로고    scopus 로고
    • ATP-binding cassette transporter A1, fatty acids, and cholesterol absorption
    • Brousseau Me. ATP-binding cassette transporter A1, fatty acids, and cholesterol absorption. Curr. Opin. Lipidol. 14 1 (2003) 35-40
    • (2003) Curr. Opin. Lipidol. , vol.14 , Issue.1 , pp. 35-40
    • Brousseau, Me.1
  • 5
    • 0038193542 scopus 로고    scopus 로고
    • Liver X receptor-dependent repression of matrix metalloproteinase-9 expression in macrophages
    • Castrillo A., Joseph S.B., Marathe C., Mangelsdorf D.J., and Tontonoz P. Liver X receptor-dependent repression of matrix metalloproteinase-9 expression in macrophages. J. Biol. Chem. 278 12 (2003) 10443-10449
    • (2003) J. Biol. Chem. , vol.278 , Issue.12 , pp. 10443-10449
    • Castrillo, A.1    Joseph, S.B.2    Marathe, C.3    Mangelsdorf, D.J.4    Tontonoz, P.5
  • 6
    • 0034953105 scopus 로고    scopus 로고
    • The human ATP-binding cassette (ABC) transporter superfamily
    • Dean M., Hamon Y., and Chimini G. The human ATP-binding cassette (ABC) transporter superfamily. J. Lipid Res. 42 (2001) 1007-1017
    • (2001) J. Lipid Res. , vol.42 , pp. 1007-1017
    • Dean, M.1    Hamon, Y.2    Chimini, G.3
  • 7
    • 0344737604 scopus 로고    scopus 로고
    • Activation of microglial Poly(ADP-ribose)-Polymerase-1 by cholesterol breakdown products during neuroinflammation: a link between demyelination and neuronal damage
    • Diestel A., Aktas O., Hackel D., Hake I., Meier S., Raine C.S., Nitsch R., Zipp F., and Ullrich O. Activation of microglial Poly(ADP-ribose)-Polymerase-1 by cholesterol breakdown products during neuroinflammation: a link between demyelination and neuronal damage. J. Exp. Med. 198 11 (2003) 1729-1740
    • (2003) J. Exp. Med. , vol.198 , Issue.11 , pp. 1729-1740
    • Diestel, A.1    Aktas, O.2    Hackel, D.3    Hake, I.4    Meier, S.5    Raine, C.S.6    Nitsch, R.7    Zipp, F.8    Ullrich, O.9
  • 8
    • 0036260390 scopus 로고    scopus 로고
    • Pathogenesis of multiple sclerosis: an update on immunology
    • Hemmer B., Cepok S., Nessler S., and Sommer N. Pathogenesis of multiple sclerosis: an update on immunology. Curr. Opin. Neurol. 15 3 (2002) 227-231
    • (2002) Curr. Opin. Neurol. , vol.15 , Issue.3 , pp. 227-231
    • Hemmer, B.1    Cepok, S.2    Nessler, S.3    Sommer, N.4
  • 9
    • 0037324340 scopus 로고    scopus 로고
    • Reciprocal regulation of inflammation and lipid metabolism by liver X receptors
    • Joseph S.B., Castrillo A., Lafitte B.A., Mangelsdorf D.J., and Tontonoz P. Reciprocal regulation of inflammation and lipid metabolism by liver X receptors. Nat. Med. 9 2 (2003) 213-219
    • (2003) Nat. Med. , vol.9 , Issue.2 , pp. 213-219
    • Joseph, S.B.1    Castrillo, A.2    Lafitte, B.A.3    Mangelsdorf, D.J.4    Tontonoz, P.5
  • 11
    • 0037131563 scopus 로고    scopus 로고
    • Changes in human plasma levels of the brain specific oxysterol 24S-hydroxycolesterol during progression of multiple sclerosis
    • Leoni V., Masterman T., Diczfalusy U., De Luca G., Hillert J., and Bjorkem I. Changes in human plasma levels of the brain specific oxysterol 24S-hydroxycolesterol during progression of multiple sclerosis. Neurosci. Lett. 33 (2002) 163-167
    • (2002) Neurosci. Lett. , vol.33 , pp. 163-167
    • Leoni, V.1    Masterman, T.2    Diczfalusy, U.3    De Luca, G.4    Hillert, J.5    Bjorkem, I.6
  • 13
    • 1542286032 scopus 로고    scopus 로고
    • Interferon-β treatment decreases cholesterol plasma levels in multiple sclerosis patients
    • Morra V.B., Coppola G., Orefice G., De Michele G., Vacca G., Filla A., and Bonavita V. Interferon-β treatment decreases cholesterol plasma levels in multiple sclerosis patients. Neurology 62 (2004) 829-830
    • (2004) Neurology , vol.62 , pp. 829-830
    • Morra, V.B.1    Coppola, G.2    Orefice, G.3    De Michele, G.4    Vacca, G.5    Filla, A.6    Bonavita, V.7
  • 15
    • 3042761085 scopus 로고    scopus 로고
    • Regulation of gene expression associated with acute experimental autoimmune encephalomyelitis by Lovastatin
    • Paintlia A.S., Paintlia M.K., Singh A.K., Stanislaus R., Gilg A.G., Barbosa E., and Singh I. Regulation of gene expression associated with acute experimental autoimmune encephalomyelitis by Lovastatin. J. Neurosci. Res. 77 1 (2004) 63-81
    • (2004) J. Neurosci. Res. , vol.77 , Issue.1 , pp. 63-81
    • Paintlia, A.S.1    Paintlia, M.K.2    Singh, A.K.3    Stanislaus, R.4    Gilg, A.G.5    Barbosa, E.6    Singh, I.7
  • 16
    • 0042346382 scopus 로고    scopus 로고
    • Expression of liver X receptor target genes decreases cellular amyloid β peptide secretion
    • Sun Y., Yao J., Kim T.W., and Tall A.R. Expression of liver X receptor target genes decreases cellular amyloid β peptide secretion. J. Biol. Chem. 278 30 (2003) 27688-27694
    • (2003) J. Biol. Chem. , vol.278 , Issue.30 , pp. 27688-27694
    • Sun, Y.1    Yao, J.2    Kim, T.W.3    Tall, A.R.4
  • 17
    • 0041589132 scopus 로고    scopus 로고
    • Decreased levels of the brain specific 24S-hydroxycolesterol and cholesterol precursors in serum of multiple sclerosis patients
    • Teunnissen C.E., Dijkstra C.D., Polman C.H., Hoogervorst E.L., von Bergmann K., and Lutjohann D. Decreased levels of the brain specific 24S-hydroxycolesterol and cholesterol precursors in serum of multiple sclerosis patients. Neurosci. Lett. 347 3 (2003) 159-162
    • (2003) Neurosci. Lett. , vol.347 , Issue.3 , pp. 159-162
    • Teunnissen, C.E.1    Dijkstra, C.D.2    Polman, C.H.3    Hoogervorst, E.L.4    von Bergmann, K.5    Lutjohann, D.6
  • 18
    • 11144221176 scopus 로고    scopus 로고
    • Activation of liver X receptors and retinoid receptors prevents bacterial-induced macrophage apoptosis
    • Valledor A.F., Hsu L.C., Ogawa S., Sawka-Verhelle D., Karin M., and Glass C.K. Activation of liver X receptors and retinoid receptors prevents bacterial-induced macrophage apoptosis. PNAS 101 51 (2004) 17813-17818
    • (2004) PNAS , vol.101 , Issue.51 , pp. 17813-17818
    • Valledor, A.F.1    Hsu, L.C.2    Ogawa, S.3    Sawka-Verhelle, D.4    Karin, M.5    Glass, C.K.6
  • 19
    • 0034640288 scopus 로고    scopus 로고
    • Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages. A transcriptional role for specific oxysterols
    • Venkateswaran A., Repa J.J., Lobaccaro J.M., Bronson A., Mangelsdorf D.J., and Edwards P.A. Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages. A transcriptional role for specific oxysterols. J. Biol. Chem. 275 19 (2000) 14700-14707
    • (2000) J. Biol. Chem. , vol.275 , Issue.19 , pp. 14700-14707
    • Venkateswaran, A.1    Repa, J.J.2    Lobaccaro, J.M.3    Bronson, A.4    Mangelsdorf, D.J.5    Edwards, P.A.6
  • 21
    • 0037108819 scopus 로고    scopus 로고
    • Liver X receptors in the central nervous system: from lipid homeostasis to neuronal degeneration
    • Wang L., Schuster G.U., Hultenby K., Zhang Q., Andersson S., and Gustafsson J. Liver X receptors in the central nervous system: from lipid homeostasis to neuronal degeneration. PNAS 99 21 (2002) 13878-13883
    • (2002) PNAS , vol.99 , Issue.21 , pp. 13878-13883
    • Wang, L.1    Schuster, G.U.2    Hultenby, K.3    Zhang, Q.4    Andersson, S.5    Gustafsson, J.6
  • 23
    • 10644229420 scopus 로고    scopus 로고
    • Statins inhibit synthesis of an oxysterol ligand for the liver X receptor in human macrophages with consequences for cholesterol efflux
    • Wong J., Quinn C.M., and Brown A.J. Statins inhibit synthesis of an oxysterol ligand for the liver X receptor in human macrophages with consequences for cholesterol efflux. Arterioscler. Thromb. Vasc. Biol. 24 12 (2004) 2365-2371
    • (2004) Arterioscler. Thromb. Vasc. Biol. , vol.24 , Issue.12 , pp. 2365-2371
    • Wong, J.1    Quinn, C.M.2    Brown, A.J.3
  • 24
    • 33845748205 scopus 로고    scopus 로고
    • SREBP-2 positively regulates transcription of the cholesterol efflux gene, ABCA1, by generating oxysterol ligands for LXR
    • Wong J., Quinn C.M., and Brown A.J. SREBP-2 positively regulates transcription of the cholesterol efflux gene, ABCA1, by generating oxysterol ligands for LXR. Biochem. J. 400 3 (2006) 485-491
    • (2006) Biochem. J. , vol.400 , Issue.3 , pp. 485-491
    • Wong, J.1    Quinn, C.M.2    Brown, A.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.