The concise synthesis of chalcone, indanone and indenone analogues of combretastatin A4

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 9, 2007, Pages 3290-3298

  Kerr, Daniel J ^a   Hamel, Ernest ^b   Jung, M Katherine ^c   Flynn, Bernard L ^a  

^a MONASH UNIVERSITY   (Australia)

^b Developmental Therapeutics Program   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Chalcone; Indanone; Indenone; Tubulin polymerisation inhibitor

Indexed keywords

2,3 BIS(4 METHOXYPHENYL) 1 (3,4,5 TRIMETHOXYPHENYL)PROP 2 EN 1 ONE; CHALCONE; COMBRETASTATIN A4; INDANONE DERIVATIVE; INDENE DERIVATIVE; TUBULIN; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN MCF 7; CONTROLLED STUDY; CYCLIZATION; CYCLOADDITION; DRUG ACTIVITY; DRUG OXIDATION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; NONHUMAN; POLYMERIZATION; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; SUBSTITUTION REACTION;

ANIMALS; BRAIN; CATTLE; CELL LINE, TUMOR; CELL PROLIFERATION; CHALCONE; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; INDANS; INDENES; MOLECULAR STRUCTURE; STEREOISOMERISM; STILBENES; STRUCTURE-ACTIVITY RELATIONSHIP; TUBULIN;

EID: 33947717991     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.02.006     Document Type: Article

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