The synthesis of indanones related to combretastatin A-4 via microwave-assisted Nazarov cyclization of chalcones

Tetrahedron Letters

Volumn 47, Issue 10, 2006, Pages 1637-1640

  Lawrence, Nicholas J ^a   Armitage, E Simon M ^a,b   Greedy, Benjamin ^a,b   Cook, Darren ^c   Ducki, Sylvie ^c   McGown, Alan T ^c  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^b CARDIFF UNIVERSITY   (United Kingdom)

^c UNIVERSITY OF SALFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,4 TRIMETHOXYPHENYL; 2,4 DICHLOROPHENYL; 2,6 DICHLOROPHENYL; 3 BROMO 4 METHOXYPHENYL; 3 FLUORO 4 METHOXYPHENYL; 3 HYDROXY 4 METHOXYPHENYL; 3 NITRO 4 METHOXYPHENYL; 3,4 DICHLOROPHENYL; 3,4,5 TRIMETHOXYPHENYL; 4 BROMOPHENYL; 4 CHLOROPHENYL; 4 METHOXYPHENYL; BENZO[DEXTRO][1,3]DIOXOL 5 YL; CHALCONE DERIVATIVE; COMBRETASTATIN A4; INDANONE DERIVATIVE; PHENYL 4 OXYACETIC ACID; TUBULIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BIOLOGICAL ACTIVITY; CATALYSIS; CELL GROWTH; CELL STRAIN K 562; CHEMICAL ANALYSIS; CHEMICAL BINDING; CHEMICAL STRUCTURE; CONFORMATION; CYCLIZATION; DRUG ACTIVITY; DRUG SAFETY; DRUG STRUCTURE; DRUG SYNTHESIS; GROWTH INHIBITION; HEATING; HUMAN; HUMAN CELL; IC 50; MICROWAVE IRRADIATION;

EID: 31944452192     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2005.12.110     Document Type: Article

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