HIV-1 reverse transcriptase pausing at bulky 2′ adducts is relieved by deletion of the RNase H domain

RNA Biology

Volumn 3, Issue 4, 2006, Pages 163-169

  Patterson, James T ^a   Nickens, David G ^a   Burke, Donald H ^a,b  

^a INDIANA UNIVERSITY   (United States)

^b University of Missouri   (United States)

Author keywords

2 adduct; Avian myeloblastosis virus; Human immunodeficiency virus; Moloney murine leukemia virus; Reverse transcriptase; RNase H domain; RT pausing; Steric barrier; Translesion polymerization

Indexed keywords

RIBONUCLEASE H; RNA DIRECTED DNA POLYMERASE;

ARTICLE; ENZYME ACTIVITY; ENZYME SPECIFICITY; GENE DELETION; HUMAN IMMUNODEFICIENCY VIRUS 1; INTERACTIONS WITH RNA; PROTEIN DOMAIN; PROTEIN RNA BINDING; RNA ADDUCT;

AVIAN MYELOBLASTOSIS VIRUS; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; MOLONEY MURINE LEUKEMIA VIRUS;

EID: 33947699938     PISSN: 15476286     EISSN: 15558584     Source Type: Journal    
DOI: 10.4161/rna.3.4.4020     Document Type: Article

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