Mutations within the primer grip region of HIV-1 reverse transcriptase result in loss of RNase H function

Journal of Biological Chemistry

Volumn 272, Issue 17, 1997, Pages 11157-11164

  Palaniappan, Chockalingam ^a   Wisniewski, Michele ^a   Jacques, Pamela S ^b   Le Grice, Stuart F J ^b   Fay, Philip J ^a   Bambara, Robert A ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEPARIN; MUTANT PROTEIN; RIBONUCLEASE H; RNA DIRECTED DNA POLYMERASE;

AMINO ACID SUBSTITUTION; ARTICLE; DNA SYNTHESIS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME MECHANISM; GENE MUTATION; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; RNA CLEAVAGE; VIRUS REPLICATION;

BINDING SITES; HIV-1; HIV-1 REVERSE TRANSCRIPTASE; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN BINDING; RIBONUCLEASE H, CALF THYMUS; RNA, VIRAL; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0030966369     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.17.11157     Document Type: Article

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