γ-glutamyl transpeptidase, an ecto-enzyme regulator of intracellular redox potential, is a component of TM4 signal transduction complexes

European Journal of Immunology

Volumn 28, Issue 12, 1998, Pages 4123-4129

  Nichols, Timothy C ^a   Guthridge, Joel M ^a   Karp, David R ^b   Molina, Hector ^c   Fletcher, Dana R ^a   Holers, V Michael ^a,d  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF COLORADO   (United States)

Author keywords

CD19 CD21; Complement; Lymphocyte; Redox regulation; Tetraspan 4

Indexed keywords

CD19 ANTIGEN; CD81 ANTIGEN; COMPLEMENT COMPONENT C3D RECEPTOR; GAMMA GLUTAMYLTRANSFERASE; GLUTATHIONE; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY;

ANTIGEN EXPRESSION; ARTICLE; B LYMPHOCYTE; CELL ADHESION; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; OXIDATION REDUCTION POTENTIAL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

EID: 0031739195     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(199812)28:12<4123::AID-IMMU4123>3.0.CO;2-G     Document Type: Article

References (16)

1. Ahearn, J. M. and Fearon, D. T., Structure and function of the complement receptors, CR1 (CD35) and CR2 (CD21). Adv. Immunol. 1989. 46: 183-219.
2. Molina, H., Holers, V. M., Li, B., Fang, Y.-F., Mariathasan, S., Goellner, F., Strauss-Schoenberger, J., Karr, R. W. and Chaplin, D. D., Markedly impaired humoral immune response in mice deficient in complement receptors 1 and 2. Proc. Natl. Acad. Sd. USA 1996. 93: 3357-3361.
3. Bradbury, L. E., Kansas, G. S., Levy, S., Evans, R. L. and Tedder, T. F., The CD19/CD21 signal transducing complex of human B lymphocytes includes the target of antiproliferative antibody-1 and Leu-13 molecules. J. Immunol. 1992. 149: 2841-2850.
4. Angelisova, P. and Horejsi, V., Association of four antigens of the tetraspan family (CD37, CD53, Tapa-1 and R2/C33) with MHC class II glycoproteins. Immunogenetics 1994. 39: 249-256.
5. Wright, M. D. and Tomlinson, M. G., The ins and outs of the transmembrane 4 superfamily. Immunol. Today 1994. 15: 588-594.
6. Maecher, H. T. and Levy, S., Normal lymphocyte development but delayed humoral immune response in CD81-null mice. J. Exp. Med. 1997. 185: 1505-1510.
7. Luxembourg, A. T. and Cooper, N. R., Modulation of signaling via the B cell antigen receptor by CD21, the receptor for C3dg and EBV. J. Immunol. 1994. 153: 4448-4457.
8. Lieberman, M. W., Barrios, R., Habib, G. M., Lebovitz, R. M., Rajagopalan, S., Sepulveda, A. R., Shi, Z. and Wan, D., Gamma-glutamyl transpeptidase: What does the organization and expression of a multipromotor gene tell us about its function? Am. J. Pathol. 1997. 147: 1175-1185.
9. Grisk, O., Kuster, U. and Ansorge, S., The activity of gamma-glutamyl transpeptidase in populations of mononuclear cells from human peripheral blood. Biol. Chem. Hoppe-Seyler 1993. 374: 287-290.
10. Goodspeed, D. C., Dunn, T. J., Miller, C. D. and Pitot, H. C., Human gamma-glutamyl transpeptidase cDNA: Comparison of hepatoma and kidney mRNA in the human and rat. Gene 1987. 76: 1-9.
11. Meister, A., Tate, S. S. and Griffith, O. W., Gamma-glutamyl transpeptidase. Methods Enzymol. 1997. 77: 237-253.
12. Lieberman, M. W., Wiseman, A. L., Shi, Z.-Z., Carter, B. Z., Barrios, R., Ou, C.-N., Chevez-Barrios, P., Wang, Y., Habib, G. M., Goodman, J. C., Huang, S. L., Lebovitz, R. M. and Matzuk, M. M., Growth retardation and cysteine deficiency in γ-glutamyl transpeptidase-deficient mice. Proc. Natl. Acad. Sci. USA 1996. 93: 7923-7926.
13. Schreck, R., Rieber, P. and Baeuerle, P. A., Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-(greek small letter script kappa)B transcription factor and HIV-1. EMBO J. 1991. 10: 2247-2258.
14. Schick, M. R., Nguyen, V. Q. and Levy, S., Anti-TAPA-1 antibodies induce protein tyrosine phosphorylation that is prevented by increasing intracellular thiol levels. J. Immunol. 1993. 151: 1918-1925.
15. Hanigan, M. H. and Ricketts, W. A., Extracellular glutathione is a source of cysteine for cells that express gamma-glutamyl transpeptidase. Biochemistry 1993. 32: 6302-6306.
16. Sepulveda, F. V., Burton, K. A. and Pearson, J. D., The development of gamma-glutamyl transferase in a pig renal-epithelial cell line in vitro. Biochem. J. 1982. 208: 509-512.