Glutathione and immune function

Proceedings of the Nutrition Society

Volumn 59, Issue 4, 2000, Pages 595-600

  Droge, W ^a   Breitkreutz, R ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Cysteine; Glutathione; Immunity

Indexed keywords

ACETYLCYSTEINE; ANTIRETROVIRUS AGENT; CYSTINE; GLUTAMINE; GLUTATHIONE; PLACEBO;

AMINO ACID METABOLISM; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DISEASE ASSOCIATION; GLUTATHIONE METABOLISM; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE SYSTEM; LYMPHOCYTE FUNCTION; NUTRITIONAL DEFICIENCY; PROTEIN DEGRADATION; PROTEIN URINE LEVEL; RANDOMIZED CONTROLLED TRIAL; VIRUS INFECTION;

HUMAN IMMUNODEFICIENCY VIRUS;

EID: 0034537186     PISSN: 00296651     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0029665100000847     Document Type: Article

References (50)

1. Role of redox potential and reactive oxygen species in stress signaling
2. Effect of N-acetylcysteine (NAC) treatment on HIV-1 infection: A double-blind placebo-controlled trial
3. Some effects of methionine on the utilization of nitrogen in the adult dog
4. Nutritional and metabolic aspects of glutathione
5. + T cells from aged rhesus monkeys
6. Massive loss of sulphur in HIV infection
7. Improvement of immune functions in HIV infection by sulfur supplementation two randomized trials
8. Systemic glutathione deficiency in symptom-free HIV-seropositive individuals
9. Glutathione depletion in HIV-infected patients: Role of cysteine deficiency and effect of oral N-acetylcysteine
10. Metabolische Storungen bei HIV-Infektion
11. N-acetyl-cysteine in the therapy of HIV-positive patients
12. HIV-induced cysteine deficiency and T cell dysfunctions - A rationale for treatment with N-acetyl-cysteine
13. Abnormal amino acid concentrations in the blood of patients with acquired immune deficiency syndrome (AIDS) may contribute to the immunological defect
14. Role of cysteine and glutathione in HIV infection and other diseases associated with muscle wasting and immunological dysfunction
15. Function of glutathione and glutathione disulfide in immunology and immunopathology
16. Low concentrations of acid soluble thiol (cysteine) in the blood plasma of HIV-1 infected patients
17. Metabolic disorder as an early consequence of simian immunodeficiency virus infection in rhesus monkeys
18. Enhancement by reducing agents of the transformation of human and rabbit peripheral lymphocytes
19. Distinct effects of glutathione disulphide on the nuclear transcription factor kappa B and the activator protein-1
20. Differential effects of glutathione depletion on T cell subsets
21. Macrophages regulate intracellular glutathione levels of lymphocytes
22. Interleukin-2 mRNA expression, lymphokine production and DNA synthesis in glutathione-depleted T cells
23. Elevated hepatic γ-glutamylcysteine synthetase activity and abnormal sulfate levels in liver and muscle tissue may explain abnormal cysteine and glutathione levels in SIV-infected rhesus macaques
24. Cystine levels, cystine flux and protein catabolism in cancer cachexia, HIV/SIV infection and senescence
25. The role of glutathione in lymphocyte activation. I. Comparison of inhibitory effects of buthionine sulfoximine and 2-cyclohexene-1-one by nuclear size transformation
26. Glutathione deficiency is associated with impaired survival in HIV disease
27. Changes in plasma amino acid concentrations in response to HIV-1 infection
28. Regulation of glutathione levels in mouse spleen lymphocytes by transport of cysteine
29. Erythrocyte glutathione deficiency in symptom-free HIV infection is associated with decreased synthesis rate
30. + cells
31. Expression of increased immunogenicity by thiol releasing tumor variants
32. IL-2 gene expression and NF-κB activation through CD28 requires reactive oxygen production by 5-lipoxygenase
33. Effect of methionine supplementation of a protein-free diet on the nitrogen excretion in rats and pigs
34. Selective modification of glutathione metabolism
35. Glutathione
36. 2 and antioxidants have opposite effects on activation of NF-κB and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor
37. Inhibition of HIV-1 replication and NF-κB activity by cysteine and cysteine derivatives
38. Redox regulation of cellular activation
39. Effect of dietary methionine and arginine on the excretion of nitrogen in cocks fed on a protein-free diet
40. Alveolar fluid glutathione decreases in asymptomatic HIV-seropositive subjects over time
41. CD4 and CD8 T cells with high intracellular glutathione levels are selectively lost as HIV infection progresses
42. Regulation oft cell activation and T cell growth factor (TCGF) production by hydrogen peroxide
43. Regulation of interleukin-2 production, interleukin 2 mRNA expression and intracellular glutathione levels in ex vivo derived T lymphocytes by lactate
44. Glutathione reverses the inhibition of T cell responses by superoptimal numbers of 'non-professional' antigen presenting cells
45. Distinct effects of thioredoxin and antioxidants on the activation of NFκB and AP-1
46. ReactiVe oxygen intermediates as apparently widely used messengers in the activation of the NFκB transcription factor and HIV-1
47. Glutathione deficiency and human immunodeficiency virus infection
48. Oxidative stress and thiol depletion in plasma and peripheral blood lymphocytes from HIV-infected patients: Toxicological and pathological implications
49. Cystine is the first limiting amino acid for utilization of endogenous amino acids in chicks fed a protein-free diet
50. Nitrogen sparing action of methionine and threonine in rats receiving a protein-free diet