-
1
-
-
1342327559
-
Regional gene therapy to enhance bone repair
-
Baltzer AW, Lieberman JR. 2004. Regional gene therapy to enhance bone repair. Gene Ther 11:344-350.
-
(2004)
Gene Ther
, vol.11
, pp. 344-350
-
-
Baltzer, A.W.1
Lieberman, J.R.2
-
2
-
-
0032758946
-
Tissue engineering of bone. Cell based strategies
-
Bruder SP, Fox BS. 1999. Tissue engineering of bone. Cell based strategies. Clin Orthop 367(Suppl):S68-S83.
-
(1999)
Clin Orthop
, vol.367
, Issue.SUPPL.
-
-
Bruder, S.P.1
Fox, B.S.2
-
3
-
-
0031012465
-
Growth kinetics, self-renewal, and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following cryopreservation
-
Bruder SP, Jaiswal N, Haynesworth SE. 1997. Growth kinetics, self-renewal, and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following cryopreservation. J Cell Biochem 64:278-294.
-
(1997)
J Cell Biochem
, vol.64
, pp. 278-294
-
-
Bruder, S.P.1
Jaiswal, N.2
Haynesworth, S.E.3
-
4
-
-
0036166573
-
Nonallograft osteoconductive bone graft substitutes
-
Bucholz RW. 2002. Nonallograft osteoconductive bone graft substitutes. Clin Orthop 395:44-52.
-
(2002)
Clin Orthop
, vol.395
, pp. 44-52
-
-
Bucholz, R.W.1
-
5
-
-
0036830322
-
Cell-type-dependent up-regulation of in vitro mineralization after overexpression of the osteoblast-specific transcription factor Runx2/Cbfa1
-
Byers BA, Pavlath GK, Murphy TJ, Karsenty G, Garcia AJ. 2002. Cell-type-dependent up-regulation of in vitro mineralization after overexpression of the osteoblast-specific transcription factor Runx2/Cbfa1. J Bone Miner Res 17:1931-1944.
-
(2002)
J Bone Miner Res
, vol.17
, pp. 1931-1944
-
-
Byers, B.A.1
Pavlath, G.K.2
Murphy, T.J.3
Karsenty, G.4
Garcia, A.J.5
-
6
-
-
11144238386
-
Synergy between genetic and tissue engineering: Runx2 overexpression and in vitro construct development enhance in vivo mineralization
-
Byers BA, Guldberg RE, Garcia AJ. 2004. Synergy between genetic and tissue engineering: Runx2 overexpression and in vitro construct development enhance in vivo mineralization. Tissue Eng 10:1757-1766.
-
(2004)
Tissue Eng
, vol.10
, pp. 1757-1766
-
-
Byers, B.A.1
Guldberg, R.E.2
Garcia, A.J.3
-
7
-
-
0035914417
-
Suppression of tumor necrosis factor-mediated apoptosis by nuclear factor kappaB-independent bone morphogenetic protein/Smad signaling
-
Chen S, Guttridge DC, Tang E, Shi S, Guan K, Wang CY. 2001. Suppression of tumor necrosis factor-mediated apoptosis by nuclear factor kappaB-independent bone morphogenetic protein/Smad signaling. J Biol Chem 276:39259-39263.
-
(2001)
J Biol Chem
, vol.276
, pp. 39259-39263
-
-
Chen, S.1
Guttridge, D.C.2
Tang, E.3
Shi, S.4
Guan, K.5
Wang, C.Y.6
-
8
-
-
17444408557
-
Runx2 regulates FGF2-induced Bmp2 expression during cranial bone development
-
Choi KY, Kim HJ, Lee MH, Kwon TG, Nah HD, Furuichi T, Komori T, Nam SH, Kim YJ, Kim HJ, Ryoo HM. 2005. Runx2 regulates FGF2-induced Bmp2 expression during cranial bone development. Dev Dyn 233:115-121.
-
(2005)
Dev Dyn
, vol.233
, pp. 115-121
-
-
Choi, K.Y.1
Kim, H.J.2
Lee, M.H.3
Kwon, T.G.4
Nah, H.D.5
Furuichi, T.6
Komori, T.7
Nam, S.H.8
Kim, Y.J.9
Kim, H.J.10
Ryoo, H.M.11
-
9
-
-
0142104985
-
Smad-dependent and Smad-independent pathways in TGF-beta family signalling
-
Derynck R, Zhang YE. 2003. Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature 425:577-584.
-
(2003)
Nature
, vol.425
, pp. 577-584
-
-
Derynck, R.1
Zhang, Y.E.2
-
10
-
-
0034782980
-
Critical aspects of tissue-engineered therapy for bone regeneration
-
Doll B, Sfeir C, Winn S, Huard J, Hollinger J. 2001. Critical aspects of tissue-engineered therapy for bone regeneration. Crit Rev Eukaryot Gene Expr 11:173-198.
-
(2001)
Crit Rev Eukaryot Gene Expr
, vol.11
, pp. 173-198
-
-
Doll, B.1
Sfeir, C.2
Winn, S.3
Huard, J.4
Hollinger, J.5
-
11
-
-
0030678549
-
Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation
-
Ducy P, Zhang R, Geoffroy V, Ridall AL, Karsenty G. 1997. Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation. Cell 89:747-754.
-
(1997)
Cell
, vol.89
, pp. 747-754
-
-
Ducy, P.1
Zhang, R.2
Geoffroy, V.3
Ridall, A.L.4
Karsenty, G.5
-
12
-
-
0036514908
-
Bone-grafting and bone-graft substitutes
-
Finkemeier CG. 2002. Bone-grafting and bone-graft substitutes. J Bone Joint Surg Am 84-A 454-464.
-
(2002)
J Bone Joint Surg Am
, vol.84-A
, pp. 454-464
-
-
Finkemeier, C.G.1
-
13
-
-
1042289598
-
Gene therapy approaches for bone regeneration
-
Franceschi RT, Yang S, Rutherford RB, Krebsbach PH, Zhao M, Wang D. 2004. Gene therapy approaches for bone regeneration. Cells Tissues Organs 176:95-108.
-
(2004)
Cells Tissues Organs
, vol.176
, pp. 95-108
-
-
Franceschi, R.T.1
Yang, S.2
Rutherford, R.B.3
Krebsbach, P.H.4
Zhao, M.5
Wang, D.6
-
14
-
-
2342646914
-
Gene therapy platform for bone regeneration using an exogenously regulated, AAV-2-based gene expression system
-
Gafni Y, Pelled G, Zilberman Y, Turgeman G, Apparailly F, Yotvat H, Galun E, Gazit Z, Jorgensen C, Gazit D. 2004. Gene therapy platform for bone regeneration using an exogenously regulated, AAV-2-based gene expression system. Mol Ther 9:587-595.
-
(2004)
Mol Ther
, vol.9
, pp. 587-595
-
-
Gafni, Y.1
Pelled, G.2
Zilberman, Y.3
Turgeman, G.4
Apparailly, F.5
Yotvat, H.6
Galun, E.7
Gazit, Z.8
Jorgensen, C.9
Gazit, D.10
-
15
-
-
0033084785
-
Engineered pluripotent mesenchymal cells integrate and differentiate in regenerating bone: A novel cell-mediated gene therapy
-
Gazit D, Turgeman G, Kelley P, Wang E, Jalenak M, Zilberman Y, Moutsatsos I. 1999. Engineered pluripotent mesenchymal cells integrate and differentiate in regenerating bone: A novel cell-mediated gene therapy. J Gene Med 1:121-133.
-
(1999)
J Gene Med
, vol.1
, pp. 121-133
-
-
Gazit, D.1
Turgeman, G.2
Kelley, P.3
Wang, E.4
Jalenak, M.5
Zilberman, Y.6
Moutsatsos, I.7
-
16
-
-
4744366089
-
Runx2/Cbfa1 stimulates transdifferentiation of primary skeletal myoblasts into a mineralizing osteoblastic phenotype
-
Gersbach CA, Byers BA, Pavlath GK, Garcia AJ. 2004a. Runx2/Cbfa1 stimulates transdifferentiation of primary skeletal myoblasts into a mineralizing osteoblastic phenotype. Exp Cell Res 300:406-417.
-
(2004)
Exp Cell Res
, vol.300
, pp. 406-417
-
-
Gersbach, C.A.1
Byers, B.A.2
Pavlath, G.K.3
Garcia, A.J.4
-
17
-
-
8744248157
-
Runx2/Cbfa1-genetically engineered skeletal myoblasts mineralize collagen scaffolds in vitro
-
Gersbach CA, Byers BA, Pavlath GK, Guldberg RE, Garcia AJ. 2004b. Runx2/Cbfa1-genetically engineered skeletal myoblasts mineralize collagen scaffolds in vitro. Biotechnol Bioeng 88:369-378.
-
(2004)
Biotechnol Bioeng
, vol.88
, pp. 369-378
-
-
Gersbach, C.A.1
Byers, B.A.2
Pavlath, G.K.3
Guldberg, R.E.4
Garcia, A.J.5
-
19
-
-
0034601692
-
Regulation of the promoters for the human bone morphogenetic protein 2 and 4 genes
-
Helvering LM, Sharp RL, Ou X, Geiser AG. 2000. Regulation of the promoters for the human bone morphogenetic protein 2 and 4 genes. Gene 256:123-138.
-
(2000)
Gene
, vol.256
, pp. 123-138
-
-
Helvering, L.M.1
Sharp, R.L.2
Ou, X.3
Geiser, A.G.4
-
20
-
-
0033047422
-
Direct three-dimensional morphometric analysis of human cancellous bone: Microstructural data from spine, femur, iliac crest, and calcaneus
-
Hildebrand T, Laib A, Muller R, Dequeker J, Ruegsegger P. 1999. Direct three-dimensional morphometric analysis of human cancellous bone: Microstructural data from spine, femur, iliac crest, and calcaneus. J Bone Miner Res 14:1167-1174.
-
(1999)
J Bone Miner Res
, vol.14
, pp. 1167-1174
-
-
Hildebrand, T.1
Laib, A.2
Muller, R.3
Dequeker, J.4
Ruegsegger, P.5
-
21
-
-
2942550496
-
Transplantation of skin fibroblasts expressing BMP-2 promotes bone repair more effectively than those expressing Runx2
-
Hirata K, Tsukazaki T, Kadowaki A, Furukawa K, Shibata Y, Moriishi T, Okubo Y, Bessho K, Komori T, Mizuno A, Yamaguchi A. 2003. Transplantation of skin fibroblasts expressing BMP-2 promotes bone repair more effectively than those expressing Runx2. Bone 32:502-512.
-
(2003)
Bone
, vol.32
, pp. 502-512
-
-
Hirata, K.1
Tsukazaki, T.2
Kadowaki, A.3
Furukawa, K.4
Shibata, Y.5
Moriishi, T.6
Okubo, Y.7
Bessho, K.8
Komori, T.9
Mizuno, A.10
Yamaguchi, A.11
-
22
-
-
33748072123
-
Combination of 3D tissue engineered scaffold and non-viral gene carrier enhance in vitro DNA expression of mesenchymal stem cells
-
Hosseihkhani H, Azzam T, Kobayashi H, Hiraoka Y, Shimokawa H, Domb AJ, Tabata Y. 2006. Combination of 3D tissue engineered scaffold and non-viral gene carrier enhance in vitro DNA expression of mesenchymal stem cells. Biomaterials 27:4269-4278.
-
(2006)
Biomaterials
, vol.27
, pp. 4269-4278
-
-
Hosseihkhani, H.1
Azzam, T.2
Kobayashi, H.3
Hiraoka, Y.4
Shimokawa, H.5
Domb, A.J.6
Tabata, Y.7
-
23
-
-
13044283416
-
Osteoblast-specific gene expression after transplantation of marrow cells: Implications for skeletal gene therapy
-
Hou Z, Nguyen Q, Frenkel B, Nilsson SK, Milne M, Van Wijnen AJ, Stein JL, Quesenberry P, Lian JB, Stein GS. 1999. Osteoblast-specific gene expression after transplantation of marrow cells: Implications for skeletal gene therapy. Proc Natl Acad Sci USA 96:7294-7299.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 7294-7299
-
-
Hou, Z.1
Nguyen, Q.2
Frenkel, B.3
Nilsson, S.K.4
Milne, M.5
Van Wijnen, A.J.6
Stein, J.L.7
Quesenberry, P.8
Lian, J.B.9
Stein, G.S.10
-
24
-
-
4444222857
-
BMP-2 exerts differential effects on differentiation of rabbit bone marrow stromal cells grown in two-dimensional and three-dimensional systems and is required for in vitro bone formation in a PLGA scaffold
-
Huang W, Carlsen B, Wulur I, Rudkin G, Ishida K, Wu B, Yamaguchi DT, Miller TA. 2004. BMP-2 exerts differential effects on differentiation of rabbit bone marrow stromal cells grown in two-dimensional and three-dimensional systems and is required for in vitro bone formation in a PLGA scaffold. Exp Cell Res 299:325-334.
-
(2004)
Exp Cell Res
, vol.299
, pp. 325-334
-
-
Huang, W.1
Carlsen, B.2
Wulur, I.3
Rudkin, G.4
Ishida, K.5
Wu, B.6
Yamaguchi, D.T.7
Miller, T.A.8
-
25
-
-
0030716244
-
Growth regulation of human prostate cancer cells by bone morphogenetic protein-2
-
Ide H, Yoshida T, Matsumoto N, Aoki K, Osada Y, Sugimura T, Terada M. 1997. Growth regulation of human prostate cancer cells by bone morphogenetic protein-2. Cancer Res 57:5022-5027.
-
(1997)
Cancer Res
, vol.57
, pp. 5022-5027
-
-
Ide, H.1
Yoshida, T.2
Matsumoto, N.3
Aoki, K.4
Osada, Y.5
Sugimura, T.6
Terada, M.7
-
26
-
-
20144387650
-
Remodeling of cortical bone allografts mediated by adherent rAAV-RANKL and VEGF gene therapy
-
Ito H, Koefoed M, Tiyapatanaputi P, Gromov K, Goater JJ, Carmouche J, Zhang X, Rubery PT, Rabinowitz J, Samulski RJ, Nakamura T, Soballe K, O'Keefe RJ, Boyce BF, Schwarz EM. 2005. Remodeling of cortical bone allografts mediated by adherent rAAV-RANKL and VEGF gene therapy. Nat Med 11:291-297.
-
(2005)
Nat Med
, vol.11
, pp. 291-297
-
-
Ito, H.1
Koefoed, M.2
Tiyapatanaputi, P.3
Gromov, K.4
Goater, J.J.5
Carmouche, J.6
Zhang, X.7
Rubery, P.T.8
Rabinowitz, J.9
Samulski, R.J.10
Nakamura, T.11
Soballe, K.12
O'Keefe, R.J.13
Boyce, B.F.14
Schwarz, E.M.15
-
27
-
-
0036800319
-
Ectopic osteogenesis using adenoviral bone morphogenetic protein (BMP)-4 and BMP-6 gene transfer
-
Jane JA, Jr., Dunford BA, Kron A, Pittman DD, Sasaki T, Li JZ, Li H, Alden TD, Dayoub H, Hankins GR, Kallmes DF, Helm GA. 2002. Ectopic osteogenesis using adenoviral bone morphogenetic protein (BMP)-4 and BMP-6 gene transfer. Mol Ther 6:464-470.
-
(2002)
Mol Ther
, vol.6
, pp. 464-470
-
-
Jane Jr., J.A.1
Dunford, B.A.2
Kron, A.3
Pittman, D.D.4
Sasaki, T.5
Li, J.Z.6
Li, H.7
Alden, T.D.8
Dayoub, H.9
Hankins, G.R.10
Kallmes, D.F.11
Helm, G.A.12
-
29
-
-
1542269674
-
Simple and effective osteoinductive gene therapy by local injection of a bone morphogenetic protein-2-expressing recombinant adenoviral vector and FK506 mixture in rats
-
Kaihara S, Bessho K, Okubo Y, Sonobe J, Kawai M, Iizuka T. 2004. Simple and effective osteoinductive gene therapy by local injection of a bone morphogenetic protein-2-expressing recombinant adenoviral vector and FK506 mixture in rats. Gene Ther 11:439-447.
-
(2004)
Gene Ther
, vol.11
, pp. 439-447
-
-
Kaihara, S.1
Bessho, K.2
Okubo, Y.3
Sonobe, J.4
Kawai, M.5
Iizuka, T.6
-
30
-
-
0034425478
-
Three-dimensional cellular development is essential for ex vivo formation of human bone
-
Kale S, Biermann S, Edwards C, Tarnowski C, Morris M, Long MW. 2000. Three-dimensional cellular development is essential for ex vivo formation of human bone. Nat Biotechnol 18:954-958.
-
(2000)
Nat Biotechnol
, vol.18
, pp. 954-958
-
-
Kale, S.1
Biermann, S.2
Edwards, C.3
Tarnowski, C.4
Morris, M.5
Long, M.W.6
-
31
-
-
22644443111
-
Biological effects of rAAV-caAlk2 coating on structural allograft healing
-
Koefoed M, Ito H, Gromov K, Reynolds DG, Awad HA, Rubery PT, Ulrich-Vinther M, Soballe K, Guldberg RE, Lin AS, O'Keefe RJ, Zhang X, Schwarz EM. 2005. Biological effects of rAAV-caAlk2 coating on structural allograft healing. Mol Ther 12:212-218.
-
(2005)
Mol Ther
, vol.12
, pp. 212-218
-
-
Koefoed, M.1
Ito, H.2
Gromov, K.3
Reynolds, D.G.4
Awad, H.A.5
Rubery, P.T.6
Ulrich-Vinther, M.7
Soballe, K.8
Guldberg, R.E.9
Lin, A.S.10
O'Keefe, R.J.11
Zhang, X.12
Schwarz, E.M.13
-
32
-
-
0030684749
-
Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts
-
Komori T, Yagi H, Nomura S, Yamaguchi A, Sasaki K, Deguchi K, Shimizu Y, Bronson RT, Gao YH, Inada M, Sato M, Okamoto R, Kitamura Y, Yoshiki S, Kishimoto T. 1997. Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell 89:755-764.
-
(1997)
Cell
, vol.89
, pp. 755-764
-
-
Komori, T.1
Yagi, H.2
Nomura, S.3
Yamaguchi, A.4
Sasaki, K.5
Deguchi, K.6
Shimizu, Y.7
Bronson, R.T.8
Gao, Y.H.9
Inada, M.10
Sato, M.11
Okamoto, R.12
Kitamura, Y.13
Yoshiki, S.14
Kishimoto, T.15
-
33
-
-
0034690624
-
Gene therapy-directed osteogenesis: BMP-7-transduced human fibroblasts form bone in vivo
-
Krebsbach PH, Gu K, Franceschi RT, Rutherford RB. 2000. Gene therapy-directed osteogenesis: BMP-7-transduced human fibroblasts form bone in vivo. Hum Gene Ther 11:1201-1210.
-
(2000)
Hum Gene Ther
, vol.11
, pp. 1201-1210
-
-
Krebsbach, P.H.1
Gu, K.2
Franceschi, R.T.3
Rutherford, R.B.4
-
34
-
-
0042891942
-
BMP-2-induced Runx2 expression is mediated by Dlx5, and TGF-{beta}1 opposes the BMP-2-induced osteoblast differentiation by suppression of Dlx5 expression
-
Lee MH, Kim YJ, Kim HJ, Park HD, Kang AR, Kyung HM, Sung JH, Wozney JM, Kim HJ, Ryoo HM. 2003. BMP-2-induced Runx2 expression is mediated by Dlx5, and TGF-{beta}1 opposes the BMP-2-induced osteoblast differentiation by suppression of Dlx5 expression. J Biol Chem 278:34387-34394.
-
(2003)
J Biol Chem
, vol.278
, pp. 34387-34394
-
-
Lee, M.H.1
Kim, Y.J.2
Kim, H.J.3
Park, H.D.4
Kang, A.R.5
Kyung, H.M.6
Sung, J.H.7
Wozney, J.M.8
Kim, H.J.9
Ryoo, H.M.10
-
35
-
-
23944447628
-
Local immunomodulation with CD4 and CD8 antibodies, but not cyclosporine A, improves osteogenesis induced by ADhBMP9 gene therapy
-
Li JZ, Li H, Hankins GR, Dunford B, Helm GA. 2005. Local immunomodulation with CD4 and CD8 antibodies, but not cyclosporine A, improves osteogenesis induced by ADhBMP9 gene therapy. Gene Ther 12:1235-1241.
-
(2005)
Gene Ther
, vol.12
, pp. 1235-1241
-
-
Li, J.Z.1
Li, H.2
Hankins, G.R.3
Dunford, B.4
Helm, G.A.5
-
36
-
-
0344276470
-
Runx2/Cbfa1: A multifunctional regulator of bone formation
-
Lian JB, Stein GS. 2003. Runx2/Cbfa1: A multifunctional regulator of bone formation. Curr Pharm Des 9:2677-2685.
-
(2003)
Curr Pharm Des
, vol.9
, pp. 2677-2685
-
-
Lian, J.B.1
Stein, G.S.2
-
37
-
-
0034993673
-
Exogenously regulated stem cell-mediated gene therapy for bone regeneration
-
Moutsatsos IK, Turgeman G, Zhou S, Kurkalli BG, Pelled G, Tzur L, Kelley P, Stumm N, Mi S, Muller R, Zilberman Y, Gazit D. 2001. Exogenously regulated stem cell-mediated gene therapy for bone regeneration. Mol Ther 3:449-461.
-
(2001)
Mol Ther
, vol.3
, pp. 449-461
-
-
Moutsatsos, I.K.1
Turgeman, G.2
Zhou, S.3
Kurkalli, B.G.4
Pelled, G.5
Tzur, L.6
Kelley, P.7
Stumm, N.8
Mi, S.9
Muller, R.10
Zilberman, Y.11
Gazit, D.12
-
38
-
-
0034895190
-
Age-related decline in the osteogenic potential of human bone marrow cells cultured in three-dimensional collagen sponges
-
Mueller SM, Glowacki J. 2001. Age-related decline in the osteogenic potential of human bone marrow cells cultured in three-dimensional collagen sponges. J Cell Biochem 82:583-590.
-
(2001)
J Cell Biochem
, vol.82
, pp. 583-590
-
-
Mueller, S.M.1
Glowacki, J.2
-
39
-
-
0011816432
-
Retroviral vectors applied to gene regulation studies
-
Murphy TJ, Pavlath GK, Wang X, Boss V, Abbott KL, Robida AM, Nichols J, Xu K, Ellington ML, Loss JR. 2002. Retroviral vectors applied to gene regulation studies. Methods Enzymol 345:539-551.
-
(2002)
Methods Enzymol
, vol.345
, pp. 539-551
-
-
Murphy, T.J.1
Pavlath, G.K.2
Wang, X.3
Boss, V.4
Abbott, K.L.5
Robida, A.M.6
Nichols, J.7
Xu, K.8
Ellington, M.L.9
Loss, J.R.10
-
40
-
-
0032904745
-
Adenovirus-mediated direct gene therapy with bone morphogenetic protein-2 produces bone
-
Musgrave DS, Bosch P, Ghivizzani S, Robbins PD, Evans CH, Huard J. 1999. Adenovirus-mediated direct gene therapy with bone morphogenetic protein-2 produces bone. Bone 24:541-547.
-
(1999)
Bone
, vol.24
, pp. 541-547
-
-
Musgrave, D.S.1
Bosch, P.2
Ghivizzani, S.3
Robbins, P.D.4
Evans, C.H.5
Huard, J.6
-
41
-
-
0036021077
-
Core-binding factor alpha 1 (Cbfa1) induces osteoblastic differentiation of C2C12 cells without interactions with Smad1 and Smad5
-
Nishimura R, Hata K, Harris SE, Ikeda F, Yoneda T. 2002. Core-binding factor alpha 1 (Cbfa1) induces osteoblastic differentiation of C2C12 cells without interactions with Smad1 and Smad5. Bone 31:303-312.
-
(2002)
Bone
, vol.31
, pp. 303-312
-
-
Nishimura, R.1
Hata, K.2
Harris, S.E.3
Ikeda, F.4
Yoneda, T.5
-
42
-
-
3042734229
-
Development of a self-inactivating tet-on retroviral vector expressing bone morphogenetic protein 4 to achieve regulated bone formation
-
Peng H, Usas A, Gearhart B, Young B, Olshanski A, Huard J. 2004. Development of a self-inactivating tet-on retroviral vector expressing bone morphogenetic protein 4 to achieve regulated bone formation. Mol Ther 9:885-894.
-
(2004)
Mol Ther
, vol.9
, pp. 885-894
-
-
Peng, H.1
Usas, A.2
Gearhart, B.3
Young, B.4
Olshanski, A.5
Huard, J.6
-
43
-
-
22644434623
-
Noggin improves bone healing elicited by muscle stem cells expressing inducible BMP4
-
Peng H, Usas A, Hannallah D, Olshanski A, Cooper GM, Huard J. 2005. Noggin improves bone healing elicited by muscle stem cells expressing inducible BMP4. Mol Ther 12:239-246.
-
(2005)
Mol Ther
, vol.12
, pp. 239-246
-
-
Peng, H.1
Usas, A.2
Hannallah, D.3
Olshanski, A.4
Cooper, G.M.5
Huard, J.6
-
44
-
-
0033065993
-
Bone repair techniques, bone graft, and bone graft substitutes
-
Perry CR. 1999. Bone repair techniques, bone graft, and bone graft substitutes. Clin Orthop 360:71-86.
-
(1999)
Clin Orthop
, vol.360
, pp. 71-86
-
-
Perry, C.R.1
-
45
-
-
33644966988
-
Glucocorticoid-induced osteogenesis is negatively regulated by Runx2/Cbfa1 serine phosphorylation
-
Phillips JE, Gersbach CA, Wojtowicz AM, Garcia AJ. 2006a. Glucocorticoid-induced osteogenesis is negatively regulated by Runx2/Cbfa1 serine phosphorylation. J Cell Sci 119:581-591.
-
(2006)
J Cell Sci
, vol.119
, pp. 581-591
-
-
Phillips, J.E.1
Gersbach, C.A.2
Wojtowicz, A.M.3
Garcia, A.J.4
-
46
-
-
33746824572
-
Mineralization capacity of Runx2/Cbfa1-genetically engineered fibroblasts is scaffold dependent
-
Phillips JE, Hutmacher DW, Guldberg RE, Garcia AJ. 2006b. Mineralization capacity of Runx2/Cbfa1-genetically engineered fibroblasts is scaffold dependent. Biomaterials 27:5535-5545.
-
(2006)
Biomaterials
, vol.27
, pp. 5535-5545
-
-
Phillips, J.E.1
Hutmacher, D.W.2
Guldberg, R.E.3
Garcia, A.J.4
-
47
-
-
33645351946
-
BMP signaling is required for RUKX2-dependent induction of the osteoblast phenotype
-
Phimphilai M, Zhao Z, Boules H, Roca H, Franceschi RT. 2006. BMP signaling is required for RUKX2-dependent induction of the osteoblast phenotype. J Bone Miner Res 21:637-646.
-
(2006)
J Bone Miner Res
, vol.21
, pp. 637-646
-
-
Phimphilai, M.1
Zhao, Z.2
Boules, H.3
Roca, H.4
Franceschi, R.T.5
-
48
-
-
1942441646
-
Efficient bone formation by gene transfer of human LIM mineralization protein-3
-
Pola E, Gao W, Zhou Y, Pola R, Lattanzi W, Sfeir C, Gambotto A, Robbins PD. 2004. Efficient bone formation by gene transfer of human LIM mineralization protein-3. Gene Ther 11:683-693.
-
(2004)
Gene Ther
, vol.11
, pp. 683-693
-
-
Pola, E.1
Gao, W.2
Zhou, Y.3
Pola, R.4
Lattanzi, W.5
Sfeir, C.6
Gambotto, A.7
Robbins, P.D.8
-
49
-
-
0037439923
-
Overexpression of a dominant negative type II bone morphogenetic protein receptor inhibits the growth of human breast cancer cells
-
Pouliot F, Blais A, Labrie C. 2003, Overexpression of a dominant negative type II bone morphogenetic protein receptor inhibits the growth of human breast cancer cells. Cancer Res 63:277-281.
-
(2003)
Cancer Res
, vol.63
, pp. 277-281
-
-
Pouliot, F.1
Blais, A.2
Labrie, C.3
-
50
-
-
0141705433
-
Cell growth regulatory role of Runx2 during proliferative expansion of preosteoblasts
-
Pratap J, Galindo M, Zaidi SK, Vradii D, Bhat BM, Robinson JA, Choi JY, Komori T, Stein JL, Lian JB, Stein GS, Van Wijnen AJ. 2003. Cell growth regulatory role of Runx2 during proliferative expansion of preosteoblasts. Cancer Res 63:5357-5362.
-
(2003)
Cancer Res
, vol.63
, pp. 5357-5362
-
-
Pratap, J.1
Galindo, M.2
Zaidi, S.K.3
Vradii, D.4
Bhat, B.M.5
Robinson, J.A.6
Choi, J.Y.7
Komori, T.8
Stein, J.L.9
Lian, J.B.10
Stein, G.S.11
Van Wijnen, A.J.12
-
51
-
-
0028264320
-
Primary mouse myoblast purification, characterization, and transplantation for cell-mediated gene therapy
-
Rando TA, Blau HM. 1994. Primary mouse myoblast purification, characterization, and transplantation for cell-mediated gene therapy. J Cell Biol 125:1275-1287.
-
(1994)
J Cell Biol
, vol.125
, pp. 1275-1287
-
-
Rando, T.A.1
Blau, H.M.2
-
52
-
-
0032955419
-
Bone morphogenetic proteins: An update on basic biology and clinical relevance
-
Schmitt JM, Hwang K, Winn SR, Hollinger JO. 1999. Bone morphogenetic proteins: An update on basic biology and clinical relevance. J Orthop Res 17:269-278.
-
(1999)
J Orthop Res
, vol.17
, pp. 269-278
-
-
Schmitt, J.M.1
Hwang, K.2
Winn, S.R.3
Hollinger, J.O.4
-
53
-
-
0035984715
-
Bone formation by human postnatal bone marrow stromal stem cells is enhanced by telomerase expression
-
Shi S, Gronthos S, Chen S, Reddi A, Counter CM, Robey PG, Wang CY. 2002. Bone formation by human postnatal bone marrow stromal stem cells is enhanced by telomerase expression. Nat Biotechnol 20:587-591.
-
(2002)
Nat Biotechnol
, vol.20
, pp. 587-591
-
-
Shi, S.1
Gronthos, S.2
Chen, S.3
Reddi, A.4
Counter, C.M.5
Robey, P.G.6
Wang, C.Y.7
-
54
-
-
0035984714
-
Telomerase expression extends the proliferative life-span and maintains the osteogenic potential of human bone marrow stromal cells
-
Simonsen JL, Rosada C, Serakinci N, Justesen J, Stenderup K, Rattan SI, Jensen TG, Kassem M. 2002. Telomerase expression extends the proliferative life-span and maintains the osteogenic potential of human bone marrow stromal cells. Nat Biotechnol 20:592-596.
-
(2002)
Nat Biotechnol
, vol.20
, pp. 592-596
-
-
Simonsen, J.L.1
Rosada, C.2
Serakinci, N.3
Justesen, J.4
Stenderup, K.5
Rattan, S.I.6
Jensen, T.G.7
Kassem, M.8
-
55
-
-
0030844823
-
High-efficiency retroviral infection of primary myoblasts
-
Springer ML, Blau HM. 1997. High-efficiency retroviral infection of primary myoblasts. Somat Cell Mol Genet 23:203-209.
-
(1997)
Somat Cell Mol Genet
, vol.23
, pp. 203-209
-
-
Springer, M.L.1
Blau, H.M.2
-
56
-
-
0036590661
-
The role of the osteoconductive scaffold in synthetic bone graft
-
Vaccaro AR. 2002. The role of the osteoconductive scaffold in synthetic bone graft. Orthopedics 25:s571-s578.
-
(2002)
Orthopedics
, vol.25
-
-
Vaccaro, A.R.1
-
57
-
-
0036133374
-
Bone morphogenetic proteins, extracellular matrix, and mitogen-activated protein kinase signaling pathways are required for osteoblast-specific gene expression and differentiation in MC3T3-E1 cells
-
Xiao G, Gopalakrishnan R, Jiang D, Reith E, Benson MD, Franceschi RT. 2002. Bone morphogenetic proteins, extracellular matrix, and mitogen-activated protein kinase signaling pathways are required for osteoblast-specific gene expression and differentiation in MC3T3-E1 cells. J Bone Miner Res 17:101-110.
-
(2002)
J Bone Miner Res
, vol.17
, pp. 101-110
-
-
Xiao, G.1
Gopalakrishnan, R.2
Jiang, D.3
Reith, E.4
Benson, M.D.5
Franceschi, R.T.6
-
58
-
-
0042807407
-
In vitro and in vivo synergistic interactions between the Runx2/Cbfa1 transcription factor and bone morphogenetic protein-2 in stimulating osteoblast differentiation
-
Yang S, Wei D, Wang D, Phimphilai M, Krebsbach PH, Franceschi RT. 2003. In vitro and in vivo synergistic interactions between the Runx2/Cbfa1 transcription factor and bone morphogenetic protein-2 in stimulating osteoblast differentiation. J Bone Miner Res 18:705-715.
-
(2003)
J Bone Miner Res
, vol.18
, pp. 705-715
-
-
Yang, S.1
Wei, D.2
Wang, D.3
Phimphilai, M.4
Krebsbach, P.H.5
Franceschi, R.T.6
-
59
-
-
21344467705
-
Diverse biological effect and Smad signaling of bone morphogenetic protein 7 in prostate tumor cells
-
Yang S, Zhong C, Frenkel B, Reddi AH, Roy-Burman P. 2005. Diverse biological effect and Smad signaling of bone morphogenetic protein 7 in prostate tumor cells. Cancer Res 65:5769-5777.
-
(2005)
Cancer Res
, vol.65
, pp. 5769-5777
-
-
Yang, S.1
Zhong, C.2
Frenkel, B.3
Reddi, A.H.4
Roy-Burman, P.5
-
60
-
-
0036166392
-
Osteoinductive molecules in orthopaedics: Basic science and preclinical studies
-
Yoon ST, Boden SD. 2002. Osteoinductive molecules in orthopaedics: Basic science and preclinical studies. Clin Orthop 395:33-43.
-
(2002)
Clin Orthop
, vol.395
, pp. 33-43
-
-
Yoon, S.T.1
Boden, S.D.2
-
61
-
-
23844546987
-
Combinatorial gene therapy for bone regeneration: Cooperative interactions between adenovirus vectors expressing bone morphogenetic proteins 2, 4, and 7
-
Zhao M, Zhao Z, Koh JT, Jin T, Franceschi RT. 2005a. Combinatorial gene therapy for bone regeneration: Cooperative interactions between adenovirus vectors expressing bone morphogenetic proteins 2, 4, and 7. J Cell Biochem 95:1-16.
-
(2005)
J Cell Biochem
, vol.95
, pp. 1-16
-
-
Zhao, M.1
Zhao, Z.2
Koh, J.T.3
Jin, T.4
Franceschi, R.T.5
-
62
-
-
22644440847
-
Gene transfer of the Runx2 transcription factor enhances osteogenic activity of bone marrow stromal cells in vitro and in vivo
-
Zhao Z, Zhao M, Xiao G, Franceschi RT. 2005b. Gene transfer of the Runx2 transcription factor enhances osteogenic activity of bone marrow stromal cells in vitro and in vivo. Mol Ther 12:247-253.
-
(2005)
Mol Ther
, vol.12
, pp. 247-253
-
-
Zhao, Z.1
Zhao, M.2
Xiao, G.3
Franceschi, R.T.4
-
63
-
-
1342323579
-
Cbfa1/osf2 transduced bone marrow stromal cells facilitate bone formation in vitro and in vivo
-
Zheng H, Guo Z, Ma Q, Jia H, Dang G. 2004. Cbfa1/osf2 transduced bone marrow stromal cells facilitate bone formation in vitro and in vivo. Calcif Tissue Int 74:194-203.
-
(2004)
Calcif Tissue Int
, vol.74
, pp. 194-203
-
-
Zheng, H.1
Guo, Z.2
Ma, Q.3
Jia, H.4
Dang, G.5
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