Combination of 3D tissue engineered scaffold and non-viral gene carrier enhance in vitro DNA expression of mesenchymal stem cells

Biomaterials

Volumn 27, Issue 23, 2006, Pages 4269-4278

  Hosseinkhani, Hossein ^a   Azzam, Tony ^b   Kobayashi, Hisatoshi ^a,c   Hiraoka, Yosuke ^d   Shimokawa, Hitoyata ^e   Domb, Abraham J ^b   Tabata, Yasuhiko ^d  

^a NATIONAL INSTITUTE FOR MATERIALS SCIENCE   (Japan)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^d KYOTO UNIVERSITY   (Japan)

^e Division of Bio Matrix   (Japan)

Author keywords

Cationization; Enhanced gene expression; In vitro transfection; Osteoinduction; Plasmid DNA; Scaffold

Indexed keywords

DNA; GENES; PLANT CELL CULTURE; POLYSACCHARIDES; POSITIVE IONS; TISSUE CULTURE;

CATIONIZATION; ENHANCED GENE EXPRESSION; IN VITRO TRANSFECTION; OSTEOINDUCTION; PLASMID DNA;

GENETIC ENGINEERING;

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; COLLAGEN; DEXTRAN; DNA; OSTEOCALCIN; PLASMID DNA; POLYSACCHARIDE; SPERMINE;

AMINATION; ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; GENE TARGETING; GENETIC TRANSFECTION; HETEROZYGOTE; IN VITRO STUDY; MALE; MESENCHYMAL STEM CELL; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; RAT; REDUCTION; STATISTICAL SIGNIFICANCE; TISSUE CULTURE; TISSUE ENGINEERING; VIRUS GENE;

ANIMALS; DNA; GENETIC VECTORS; MALE; MESENCHYMAL STEM CELLS; RATS; RATS, WISTAR; TISSUE ENGINEERING; TRANSFECTION;

EID: 33748072123     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2006.02.033     Document Type: Article

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