Gene transduction of an active mutant of Akt exerts cytoprotection and reduces graft injury after liver transplantation

American Journal of Transplantation

Volumn 7, Issue 4, 2007, Pages 769-778

  Morales Ruiz, M ^a   Fondevila, C ^a   Munoz Luque J ^a   Tugues, S ^a   Rodriguez Laiz G ^a   Cejudo Martin P ^a   Romero, J M ^a   Navasa, M ^a   Fuster, J ^a   Arroyo, V ^a   Sessa, W C ^b   Garcia Valdecasas J C ^a   Jimenez W ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Akt; eNos; Gene therapy; Ischemia reperfusion insury; Liver transplantation

Indexed keywords

ADENOVIRUS VECTOR; AMINOTRANSFERASE; BETA GALACTOSIDASE; CASPASE 3; ENDOTHELIAL NITRIC OXIDE SYNTHASE; LACTATE DEHYDROGENASE; METHYLPREDNISOLONE; MUTANT PROTEIN; PROTEIN KINASE B; TACROLIMUS;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENETIC TRANSDUCTION; LIVER GRAFT; LIVER GRAFT REJECTION; LIVER INJURY; LIVER TRANSPLANTATION; LIVING DONOR; NONHUMAN; ORGAN DONOR; ORTHOTOPIC TRANSPLANTATION; PRIORITY JOURNAL; REPERFUSION INJURY; SWINE; VIRAL GENE THERAPY;

ANIMALS; AORTA; CATTLE; CELL LINE; CELLS, CULTURED; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; HEPATOCYTES; HUMANS; KIDNEY; MUTATION; ONCOGENE PROTEIN V-AKT; SWINE;

EID: 33947589623     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2006.01720.x     Document Type: Article

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