N-substituted ureas and thioureas in Biginelli reaction promoted by chlorotrimethylsilane: Convenient synthesis of N1-alkyl-, N1-aryl-, and N1,N3-dialkyl-3,4-dihydropyrimidin-2(1H)-(thi)ones

Synthesis

Volumn , Issue 3, 2007, Pages 0417-0427

  Ryabukhin, Sergey V ^a,b   Plaskon, Andrey S ^a,b   Ostapchuk, Eugeniy N ^a   Volochnyuk, Dmitriy M ^a,c   Tolmachev, Andrey A ^b  

^a ENAMINE LTD   (Ukraine)

^b TARAS SHEVCHENKO NATIONAL UNIVERSITY OF KYIV   (Ukraine)

^c INSTITUTE OF ORGANIC CHEMISTRY   (Ukraine)

Author keywords

Biginelli reaction; Heterocycles; Lewis acid; Multicomponent reaction; Parallel synthesis

Indexed keywords

BIGINELLI REACTION; HETEROCYCLES; LEWIS ACID; MULTICOMPONENT REACTION; PARALLEL SYNTHESIS;

NITROGEN COMPOUNDS; SILANES; SUBSTITUTION REACTIONS; SYNTHESIS (CHEMICAL);

UREA;

3,4 DIHYDROPYRIMIDIN 2(1H) ONE; 3,4 DIHYDROPYRIMIDINE 2(1H) THIONE; CHLOROTRIMETHYLSILANE; N,N DIMETHYLFORMAMIDE; PYRIMIDINE DERIVATIVE; THIOUREA DERIVATIVE; UNCLASSIFIED DRUG; UREA DERIVATIVE;

ARTICLE; BIGINELLI REACTION; SUBSTITUTION REACTION; SYNTHESIS;

EID: 33947544770     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-965881     Document Type: Article

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