Methyl vinyl ketone induces apoptosis in murine GT1-7 hypothalamic neurons through glutathione depletion and the generation of reactive oxygen species

Free Radical Research

Volumn 41, Issue 4, 2007, Pages 469-477

  Sathishkumar, K ^a   Rangan, Viswanathan ^a   Gao, Xueli ^a   Uppu, Rao M ^a  

^a SOUTHERN UNIVERSITY   (United States)

Author keywords

, unsaturated carbonyl compounds; Apoptosis; Glutathione; Methyl vinyl ketone; Reactive oxygen species; Trolox

Indexed keywords

1,3 BUTADIENE; ACROLEIN; CROTONALDEHYDE; DNA FRAGMENT; GLUTATHIONE; KETONE DERIVATIVE; METHYLVINYL KETONE; REACTIVE OXYGEN METABOLITE; TROLOX C; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELLULAR DISTRIBUTION; CHROMATIN CONDENSATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; HYPOTHALAMUS; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MOUSE; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PROTEIN DEPLETION; TOXICITY TESTING; VITAMIN SUPPLEMENTATION;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; BUTANONES; CELL DEATH; CELL SURVIVAL; CHROMANS; DNA FRAGMENTATION; GLUTATHIONE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MEMBRANE POTENTIALS; MICE; NEURONS; REACTIVE OXYGEN SPECIES; TIME FACTORS;

MURINAE;

EID: 33947520685     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.1080/10715760601145257     Document Type: Article

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