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Science

Volumn 315, Issue 5818, 2007, Pages 1549-1553

The structural basis of ribozyme-catalyzed RNA assembly

(2) Robertson, Michael P a Scott, William G a

a UNIVERSITY OF CALIFORNIA (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAGNESIUM ION; RIBOZYME; RNA; RNA LIGASE;

CATALYSIS; CHEMICAL BONDING; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ION; MAGNESIUM; PHOSPHATE; RNA; STABILIZATION;

ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; HUMAN; NONHUMAN; PRIORITY JOURNAL; RNA SYNTHESIS; STRUCTURE ACTIVITY RELATION;

BASE PAIRING; BINDING SITES; CATALYSIS; CATALYTIC DOMAIN; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; DIRECTED MOLECULAR EVOLUTION; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR CONFORMATION; NUCLEIC ACID CONFORMATION; OLIGORIBONUCLEOTIDES; RIBONUCLEOTIDES; RNA, CATALYTIC; TEMPLATES, GENETIC;

EID: 33947389130 PISSN: 00368075 EISSN: 10959203 Source Type: Journal
DOI: 10.1126/science.1136231 Document Type: Article

Times cited : (86)

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- We thank A. Ellington, H. Noller, members of the Scott laboratory and of the RNA Center at UCSC for helpful discussions and support, and the NIH and W. M. Keck Foundation for funding. We dedicate this paper to Professor Stanley L. Miller. Coordinates and data: Fobs and coordinates have been deposited with Protein Data Bank accession code 20IU. These data, as well as the composite-omit 2Fobs, Fcalc and other electron density maps described in the paper, are available from
- calc and other electron density maps described in the paper, are available from http://xanana.ucsc.edu/L1.

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