-
1
-
-
0028143527
-
CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1
-
Kawaguchi Y, Okamoto T, Taniwaki M, et al. CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1. Nat Genet, 1994, 8 (3): 221-228
-
(1994)
Nat Genet
, vol.8
, Issue.3
, pp. 221-228
-
-
Kawaguchi, Y.1
Okamoto, T.2
Taniwaki, M.3
-
2
-
-
0345436080
-
High level expression of expanded full-length ataxin-3 in vitro causes cell death and formation of intranuclear inclusions in neuronal cells
-
Evert B O, Wullner U, Schulz J B, et al. High level expression of expanded full-length ataxin-3 in vitro causes cell death and formation of intranuclear inclusions in neuronal cells. Hum Mol Genet, 1999, 8 (7): 1169-1176
-
(1999)
Hum Mol Genet
, vol.8
, Issue.7
, pp. 1169-1176
-
-
Evert, B.O.1
Wullner, U.2
Schulz, J.B.3
-
3
-
-
18544392423
-
-
Warrick J M, Paulson H L, Gray-Board G L, et al. Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila. Cell, 1998, 93 (6): 939-949
-
Warrick J M, Paulson H L, Gray-Board G L, et al. Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila. Cell, 1998, 93 (6): 939-949
-
-
-
-
4
-
-
25844487226
-
Diseases of unstable repeat expansion: Mechanisms and common principles
-
Gatchel J R, Zoghbi H Y. Diseases of unstable repeat expansion: mechanisms and common principles. Nat Rev Genet, 2005, 6 (10): 743-755
-
(2005)
Nat Rev Genet
, vol.6
, Issue.10
, pp. 743-755
-
-
Gatchel, J.R.1
Zoghbi, H.Y.2
-
5
-
-
0141891215
-
Pathogenesis of polyglutamine disorders: Aggregation revisited
-
Michalik A, Van Broeckhoven C. Pathogenesis of polyglutamine disorders: aggregation revisited. Hum Mol Genet, 2003, 12 (2): R173-186
-
(2003)
Hum Mol Genet
, vol.12
, Issue.2
-
-
Michalik, A.1
Van Broeckhoven, C.2
-
6
-
-
2642589007
-
Autosomal dominant cerebellar ataxia: Phenotypic differences in genetically defined subtypes?
-
Schols L, Amoiridis G, Buttner T, et al. Autosomal dominant cerebellar ataxia: phenotypic differences in genetically defined subtypes?. Ann Neurol, 1997, 42 (6): 924-932
-
(1997)
Ann Neurol
, vol.42
, Issue.6
, pp. 924-932
-
-
Schols, L.1
Amoiridis, G.2
Buttner, T.3
-
7
-
-
0034093161
-
Frequency of SCA1, SCA2, SCA3/MJD, SCA6, SCA7, and DRPLA CAG trinucleotide repeat expansion in patients with hereditary spinocerebellar ataxia from Chinese kindreds
-
Tang B, Liu C, Shen L, et al. Frequency of SCA1, SCA2, SCA3/MJD, SCA6, SCA7, and DRPLA CAG trinucleotide repeat expansion in patients with hereditary spinocerebellar ataxia from Chinese kindreds. Arch Neurol, 2000, 57 (4): 540-544
-
(2000)
Arch Neurol
, vol.57
, Issue.4
, pp. 540-544
-
-
Tang, B.1
Liu, C.2
Shen, L.3
-
8
-
-
3943099375
-
Protein modification by SUMO
-
Johnson E S. Protein modification by SUMO. Annu Rev Biochem, 2004, 73: 355-382
-
(2004)
Annu Rev Biochem
, vol.73
, pp. 355-382
-
-
Johnson, E.S.1
-
9
-
-
0032475941
-
Ataxin-1 nuclear localization and aggregation: Role in polyglutamine-induced disease in SCA1 transgenic mice
-
Klement I A, Skinner P J, Kaytor M D, et al. Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice. Cell, 1998, 95 (1): 41-53
-
(1998)
Cell
, vol.95
, Issue.1
, pp. 41-53
-
-
Klement, I.A.1
Skinner, P.J.2
Kaytor, M.D.3
-
10
-
-
0037631378
-
Nuclear localization of a non-caspase truncation product of atrophin-1, with an expanded polyglutamine repeat, increases cellular toxicity
-
Nucifora F C Jr, Ellerby L M, Wellington C L, et al. Nuclear localization of a non-caspase truncation product of atrophin-1, with an expanded polyglutamine repeat, increases cellular toxicity. J Biol Chem, 2003, 278 (15): 13047-13055
-
(2003)
J Biol Chem
, vol.278
, Issue.15
, pp. 13047-13055
-
-
Nucifora Jr, F.C.1
Ellerby, L.M.2
Wellington, C.L.3
-
11
-
-
13944275615
-
Polyglutamine expansion of huntingtin impairs its nuclear export
-
Cornett J, Cao F, Wang C E, et al. Polyglutamine expansion of huntingtin impairs its nuclear export. Nat Genet, 2005, 37 (2): 198-204
-
(2005)
Nat Genet
, vol.37
, Issue.2
, pp. 198-204
-
-
Cornett, J.1
Cao, F.2
Wang, C.E.3
-
12
-
-
0031803642
-
Ataxin-3 is transported into the nucleus and associates with the nuclear matrix
-
Tait D, Riccio M, Sittler A, et al. Ataxin-3 is transported into the nucleus and associates with the nuclear matrix. Hum Mol Genet, 1998, 7 (6): 991-997
-
(1998)
Hum Mol Genet
, vol.7
, Issue.6
, pp. 991-997
-
-
Tait, D.1
Riccio, M.2
Sittler, A.3
-
13
-
-
0036578784
-
Disruption of CREB function in brain leads to neurodegeneration
-
Mantamadiotis T, Lemberger T, Bleckmann S C, et al. Disruption of CREB function in brain leads to neurodegeneration. Nat Genet, 2002, 31 (1): 47-54
-
(2002)
Nat Genet
, vol.31
, Issue.1
, pp. 47-54
-
-
Mantamadiotis, T.1
Lemberger, T.2
Bleckmann, S.C.3
-
14
-
-
0035937523
-
Interference by huntingtin and atrophin-1 with CBP-mediated transcription leading to cellular toxicity
-
Nucifora F C Jr, Sasaki M, Peters M F, et al. Interference by huntingtin and atrophin-1 with CBP-mediated transcription leading to cellular toxicity. Science, 2001, 291 (5512): 2423-2428
-
(2001)
Science
, vol.291
, Issue.5512
, pp. 2423-2428
-
-
Nucifora Jr, F.C.1
Sasaki, M.2
Peters, M.F.3
-
15
-
-
0037160106
-
Ataxin-3 is a histone-binding protein with two independent transcriptional corepressor activities
-
Li F, Macfarlan T, Pittman R N, et al. Ataxin-3 is a histone-binding protein with two independent transcriptional corepressor activities. J Biol Chem, 2002, 277 (47): 45004-45012
-
(2002)
J Biol Chem
, vol.277
, Issue.47
, pp. 45004-45012
-
-
Li, F.1
Macfarlan, T.2
Pittman, R.N.3
-
16
-
-
26444471700
-
A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma
-
Pascual G, Fong A L, Ogawa S, et al. A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma. Nature, 2005, 437 (7059): 759-763
-
(2005)
Nature
, vol.437
, Issue.7059
, pp. 759-763
-
-
Pascual, G.1
Fong, A.L.2
Ogawa, S.3
-
17
-
-
0242289453
-
Recent advances in understanding the pathogenesis of polyglutamine diseases: Involvement of molecular chaperones and ubiquitin-proteasome pathway
-
Jana N R, Nukina N. Recent advances in understanding the pathogenesis of polyglutamine diseases: involvement of molecular chaperones and ubiquitin-proteasome pathway. J Chem Neuroanat, 2003, 26 (2): 95-101
-
(2003)
J Chem Neuroanat
, vol.26
, Issue.2
, pp. 95-101
-
-
Jana, N.R.1
Nukina, N.2
-
18
-
-
0038159253
-
Parkin facilitates the elimination of expanded polyglutamine proteins and leads to preservation of proteasome function
-
Tsai Y C, Fishman P S, Thakor N V, et al. Parkin facilitates the elimination of expanded polyglutamine proteins and leads to preservation of proteasome function. J Biol Chem, 2003, 278 (24): 22044-22055.
-
(2003)
J Biol Chem
, vol.278
, Issue.24
, pp. 22044-22055
-
-
Tsai, Y.C.1
Fishman, P.S.2
Thakor, N.V.3
-
19
-
-
15444380557
-
Daxx mediates the SUMO-dependent transcriptional repression of Smad4
-
Chang C C, Lin D Y, Fang H I, et al. Daxx mediates the SUMO-dependent transcriptional repression of Smad4. J Biol Chem, 2005, 280 (11): 10164-10173
-
(2005)
J Biol Chem
, vol.280
, Issue.11
, pp. 10164-10173
-
-
Chang, C.C.1
Lin, D.Y.2
Fang, H.I.3
-
20
-
-
11144353613
-
SUMO modification of Huntingtin and Huntington's disease pathology
-
Steffan J S, Agrawal N, Pallos J, et al. SUMO modification of Huntingtin and Huntington's disease pathology. Science, 2004, 304 (5667): 100-104
-
(2004)
Science
, vol.304
, Issue.5667
, pp. 100-104
-
-
Steffan, J.S.1
Agrawal, N.2
Pallos, J.3
|