-
1
-
-
15844419153
-
Identification of a major co-receptor for primary isolates of HIV-1
-
Deng H, Liu R, Ellmeier W, et al.: Identification of a major co-receptor for primary isolates of HIV-1. Nature 1996;381:661-666.
-
(1996)
Nature
, vol.381
, pp. 661-666
-
-
Deng, H.1
Liu, R.2
Ellmeier, W.3
-
2
-
-
15844389650
-
HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5
-
Dragic T, Litwin V, Allaway GP, et al.: HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5. Nature 1996;381:667-673.
-
(1996)
Nature
, vol.381
, pp. 667-673
-
-
Dragic, T.1
Litwin, V.2
Allaway, G.P.3
-
3
-
-
0742325043
-
The CCR5 and CXCR4 coreceptors-central to understanding the transmission and pathogenesis of human immunodeficiency virus type 1 infection
-
Moore JP, Kitchen SG, Pugach P, and Zack JA: The CCR5 and CXCR4 coreceptors-central to understanding the transmission and pathogenesis of human immunodeficiency virus type 1 infection. AIDS Res Hum Retroviruses 2004;20:111-126.
-
(2004)
AIDS Res Hum Retroviruses
, vol.20
, pp. 111-126
-
-
Moore, J.P.1
Kitchen, S.G.2
Pugach, P.3
Zack, J.A.4
-
4
-
-
0030951920
-
Global distribution of the CCR5 gene 32-basepair deletion
-
Martinson JJ, Chapman NH, Rees DC, Liu YT, and Clegg JB: Global distribution of the CCR5 gene 32-basepair deletion. Nat Genet 1997;16:100-103.
-
(1997)
Nat Genet
, vol.16
, pp. 100-103
-
-
Martinson, J.J.1
Chapman, N.H.2
Rees, D.C.3
Liu, Y.T.4
Clegg, J.B.5
-
5
-
-
0033647217
-
The effect of genetic variation in chemokines and their receptors on HIV transmission and progression to AIDS
-
O'Brien SJ and Moore JP: The effect of genetic variation in chemokines and their receptors on HIV transmission and progression to AIDS. Immunol Rev 2000;177:99-111.
-
(2000)
Immunol Rev
, vol.177
, pp. 99-111
-
-
O'Brien, S.J.1
Moore, J.P.2
-
6
-
-
27844602105
-
The geographic spread of the CCR5 delta32 HIV-resistance allele
-
Novembre J, Galvani AP, and Slatkin M: The geographic spread of the CCR5 delta32 HIV-resistance allele. PLoS Biol 2005;3:e339.
-
(2005)
PLoS Biol
, vol.3
-
-
Novembre, J.1
Galvani, A.P.2
Slatkin, M.3
-
7
-
-
21244484209
-
The evolutionary history of the CCR5-delta32 HIV-resistance mutation
-
Galvani AP and Novembre J: The evolutionary history of the CCR5-delta32 HIV-resistance mutation. Microbes Infect 2005;7:302-309.
-
(2005)
Microbes Infect
, vol.7
, pp. 302-309
-
-
Galvani, A.P.1
Novembre, J.2
-
8
-
-
15844388931
-
Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection
-
Liu R, Paxton WA, Choe S, et al.: Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell 1996;86:367-377.
-
(1996)
Cell
, vol.86
, pp. 367-377
-
-
Liu, R.1
Paxton, W.A.2
Choe, S.3
-
9
-
-
0037127299
-
Reduced cell surface expression of CCR5 in CCR5delta 32 heterozygotes is mediated by gene dosage, rather than by receptor sequestration
-
Venkatesan S, Petrovic A, Van Ryk DI, Locati M, Weissman D, and Murphy PM: Reduced cell surface expression of CCR5 in CCR5delta 32 heterozygotes is mediated by gene dosage, rather than by receptor sequestration. J Biol Chem 2002;277:2287-2301.
-
(2002)
J Biol Chem
, vol.277
, pp. 2287-2301
-
-
Venkatesan, S.1
Petrovic, A.2
Van Ryk, D.I.3
Locati, M.4
Weissman, D.5
Murphy, P.M.6
-
10
-
-
0031181196
-
Host genes and HIV: The role of the chemokine receptor gene CCR5 and its allele
-
McNicholl JM, Smith DK, Qari SH, and Hodge T: Host genes and HIV: The role of the chemokine receptor gene CCR5 and its allele. Emerg Infect Dis 1997;3:261-271.
-
(1997)
Emerg Infect Dis
, vol.3
, pp. 261-271
-
-
McNicholl, J.M.1
Smith, D.K.2
Qari, S.H.3
Hodge, T.4
-
11
-
-
0031921667
-
A survey for 32 nucleotide deletion in the CCR-5 chemokine receptor gene (deltaccr-5) conferring resistance to human immunodeficiency virus type 1 in different ethnic groups and in chimpanzees
-
Voevodin A, Samilchuk E, and Dashti S: A survey for 32 nucleotide deletion in the CCR-5 chemokine receptor gene (deltaccr-5) conferring resistance to human immunodeficiency virus type 1 in different ethnic groups and in chimpanzees. J Med Virol 1998;55:147-151.
-
(1998)
J Med Virol
, vol.55
, pp. 147-151
-
-
Voevodin, A.1
Samilchuk, E.2
Dashti, S.3
-
12
-
-
0034031324
-
CD4+ T cell surface CCR5 density as a determining factor of virus load in persons infected with human immunodeficiency virus type 1
-
Reynes J, Portales P, Segondy M, et al.: CD4+ T cell surface CCR5 density as a determining factor of virus load in persons infected with human immunodeficiency virus type 1. J Infect Dis 2000;181:927-932.
-
(2000)
J Infect Dis
, vol.181
, pp. 927-932
-
-
Reynes, J.1
Portales, P.2
Segondy, M.3
-
13
-
-
0031858846
-
Human immunodeficiency virus type 1 disease progression, CCR5 genotype, and specific immune responses
-
Visco-Comandini U, Hultgren C, Brostrom C, Birk M, Kim S, and Sallberg M: Human immunodeficiency virus type 1 disease progression, CCR5 genotype, and specific immune responses. Clin Diagn Lab Immunol 1998;5:463-466.
-
(1998)
Clin Diagn Lab Immunol
, vol.5
, pp. 463-466
-
-
Visco-Comandini, U.1
Hultgren, C.2
Brostrom, C.3
Birk, M.4
Kim, S.5
Sallberg, M.6
-
14
-
-
0037435775
-
Effects of CCR5-delta32 and CCR2-64I alleles on HIV-1 disease progression: The protection varies with duration of infection
-
Mulherin SA, O'Brien TR, Ioannidis JP, et al.: Effects of CCR5-delta32 and CCR2-64I alleles on HIV-1 disease progression: The protection varies with duration of infection. AIDS 2003;17:377-387.
-
(2003)
AIDS
, vol.17
, pp. 377-387
-
-
Mulherin, S.A.1
O'Brien, T.R.2
Ioannidis, J.P.3
-
15
-
-
0035964091
-
The coreceptor mutation CCR5delta32 influences the dynamics of HIV epidemics and is selected for by HIV
-
Sullivan AD, Wigginton J, and Kirschner D: The coreceptor mutation CCR5delta32 influences the dynamics of HIV epidemics and is selected for by HIV. Proc Natl Acad Sci USA 2001;98:10214-10219.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10214-10219
-
-
Sullivan, A.D.1
Wigginton, J.2
Kirschner, D.3
-
16
-
-
24644465001
-
Combined effect of CCR5delta32 heterozygosity and the CCR5 promoter polymorphism -2459 A/G on CCR5 expression and resistance to human immunodeficiency virus type 1 transmission
-
Hladik F, Liu H, Speelmon E, et al.: Combined effect of CCR5delta32 heterozygosity and the CCR5 promoter polymorphism -2459 A/G on CCR5 expression and resistance to human immunodeficiency virus type 1 transmission. J Virol 2005;79:11677-11684.
-
(2005)
J Virol
, vol.79
, pp. 11677-11684
-
-
Hladik, F.1
Liu, H.2
Speelmon, E.3
-
17
-
-
1242342131
-
Role for CCR5Delta32 protein in resistance to R5, R5X4, and X4 human immunodeficiency virus type 1 in primary CD4+ cells
-
Agrawal L, Lu X, Qingwen J, et al.: Role for CCR5Delta32 protein in resistance to R5, R5X4, and X4 human immunodeficiency virus type 1 in primary CD4+ cells. J Virol 2004;78:2277-2287.
-
(2004)
J Virol
, vol.78
, pp. 2277-2287
-
-
Agrawal, L.1
Lu, X.2
Qingwen, J.3
-
18
-
-
0036139926
-
Distribution of chemokine receptor CCR2 and CCR5 genotypes and their relative contribution to human immunodeficiency virus type 1 (HIV-1) seroconversion, early HIV-1 RNA concentration in plasma, and later disease progression
-
Tang J, Shelton B, Makhatadze NJ, et al.: Distribution of chemokine receptor CCR2 and CCR5 genotypes and their relative contribution to human immunodeficiency virus type 1 (HIV-1) seroconversion, early HIV-1 RNA concentration in plasma, and later disease progression. J Virol 2002;76:662-672.
-
(2002)
J Virol
, vol.76
, pp. 662-672
-
-
Tang, J.1
Shelton, B.2
Makhatadze, N.J.3
-
19
-
-
0001633495
-
Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study
-
Dean M, Carrington M, Winkler C, et al.: Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study. Science 1996;273:1856-1862.
-
(1996)
Science
, vol.273
, pp. 1856-1862
-
-
Dean, M.1
Carrington, M.2
Winkler, C.3
-
20
-
-
0035881173
-
Homozygous and heterozygous CCR5-delta32 genotypes are associated with resistance to HIV infection
-
Marmor M, Sheppard HW, Donnell D, et al.: Homozygous and heterozygous CCR5-delta32 genotypes are associated with resistance to HIV infection. J Acquir Immune Defic Syndr 2001;27:472-481.
-
(2001)
J Acquir Immune Defic Syndr
, vol.27
, pp. 472-481
-
-
Marmor, M.1
Sheppard, H.W.2
Donnell, D.3
-
21
-
-
16044373004
-
Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene
-
Samson M, Libert F, Doranz BJ, et al.: Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature 1996;382:722-725.
-
(1996)
Nature
, vol.382
, pp. 722-725
-
-
Samson, M.1
Libert, F.2
Doranz, B.J.3
-
22
-
-
0031899428
-
Mutational analysis of the CCR5 and CXCR4 genes (HIV-1 co-receptors) in resistance to HIV-1 infection and AIDS development among intravenous drug users
-
Alvarez V, Lopez-Larrea C, and Coto E: Mutational analysis of the CCR5 and CXCR4 genes (HIV-1 co-receptors) in resistance to HIV-1 infection and AIDS development among intravenous drug users. Hum Genet 1998;102:483-486.
-
(1998)
Hum Genet
, vol.102
, pp. 483-486
-
-
Alvarez, V.1
Lopez-Larrea, C.2
Coto, E.3
-
23
-
-
16044367526
-
The role of a mutant CCR5 allele in HIV-1 transmission and disease progression
-
Huang Y, Paxton WA, Wolinsky SM, et al.: The role of a mutant CCR5 allele in HIV-1 transmission and disease progression. Nat Med 1996;2:1240-1243.
-
(1996)
Nat Med
, vol.2
, pp. 1240-1243
-
-
Huang, Y.1
Paxton, W.A.2
Wolinsky, S.M.3
-
24
-
-
0030860210
-
CCR2 chemokine receptor and AIDS progression
-
Smith MW, Carrington M, Winkler C, et al.: CCR2 chemokine receptor and AIDS progression. Nat Med 1997;3:1052-1053.
-
(1997)
Nat Med
, vol.3
, pp. 1052-1053
-
-
Smith, M.W.1
Carrington, M.2
Winkler, C.3
-
25
-
-
0034436621
-
High frequency of the HIV-1 protective CCR5 delta32 deletion in native Estonians
-
Kalev I, Mikelsaar AV, Beckman L, Tasa G, and Parlist P: High frequency of the HIV-1 protective CCR5 delta32 deletion in native Estonians. Eur J Epidemiol 2000;16:1107-1109.
-
(2000)
Eur J Epidemiol
, vol.16
, pp. 1107-1109
-
-
Kalev, I.1
Mikelsaar, A.V.2
Beckman, L.3
Tasa, G.4
Parlist, P.5
-
27
-
-
0036295509
-
The role of injection drug use in the emergence of human immunodeficiency virus infection in Estonia
-
Uuskula A, Kalikova A, Zilmer K, Tammai L, and DeHovitz J: The role of injection drug use in the emergence of human immunodeficiency virus infection in Estonia. Int J Infect Dis 2002;6:23-27.
-
(2002)
Int J Infect Dis
, vol.6
, pp. 23-27
-
-
Uuskula, A.1
Kalikova, A.2
Zilmer, K.3
Tammai, L.4
DeHovitz, J.5
-
29
-
-
9344246865
-
Two viral strains and a possible novel recombinant are responsible for the explosive injecting drug use-associated HIV type 1 epidemic in Estonia
-
Zetterberg V, Ustina V, Liitsola K, et al.: Two viral strains and a possible novel recombinant are responsible for the explosive injecting drug use-associated HIV type 1 epidemic in Estonia. AIDS Res Hum Retroviruses 2004;20:1148-1156.
-
(2004)
AIDS Res Hum Retroviruses
, vol.20
, pp. 1148-1156
-
-
Zetterberg, V.1
Ustina, V.2
Liitsola, K.3
-
30
-
-
0034523325
-
Envelope V3 amino acid sequence predicts HIV-1 phenotype (co-receptor usage and tropism for macrophages)
-
Briggs DR, Tuttle DL, Sleasman JW, and Goodenow MM: Envelope V3 amino acid sequence predicts HIV-1 phenotype (co-receptor usage and tropism for macrophages). AIDS 2000;14:2937-2939.
-
(2000)
AIDS
, vol.14
, pp. 2937-2939
-
-
Briggs, D.R.1
Tuttle, D.L.2
Sleasman, J.W.3
Goodenow, M.M.4
-
31
-
-
6844240236
-
The deltaccr5 mutation conferring protection against HIV-1 in Caucasian populations has a single and recent origin in Northeastern Europe
-
Libert F, Cochaux P, Beckman G, et al.: The deltaccr5 mutation conferring protection against HIV-1 in Caucasian populations has a single and recent origin in Northeastern Europe. Hum Mol Genet 1998;7:399-406.
-
(1998)
Hum Mol Genet
, vol.7
, pp. 399-406
-
-
Libert, F.1
Cochaux, P.2
Beckman, G.3
-
32
-
-
0036999990
-
Genetic recombination and its role in the development of the HIV-1 pandemic
-
Najera R, Delgado E, Perez-Alvarez L, and Thomson MM: Genetic recombination and its role in the development of the HIV-1 pandemic. AIDS 2002;16(Suppl. 4):S3-16.
-
(2002)
AIDS
, vol.16
, Issue.SUPPL. 4
-
-
Najera, R.1
Delgado, E.2
Perez-Alvarez, L.3
Thomson, M.M.4
-
33
-
-
3843072032
-
HIV-1 superinfection and viral diversity
-
Gross KL, Porco TC, and Grant RM: HIV-1 superinfection and viral diversity. AIDS 2004;18:1513-1520.
-
(2004)
AIDS
, vol.18
, pp. 1513-1520
-
-
Gross, K.L.1
Porco, T.C.2
Grant, R.M.3
-
34
-
-
0032932463
-
No evidence for an effect of the CCR5 delta32/+ and CCR2b 64I/+ mutations on human immunodeficiency virus (HIV)-1 disease progression among HIV-1-infected injecting drug users
-
Schinkel J, Langendam MW, Coutinho RA, Krol A, Brouwer M, and Schuitemaker H: No evidence for an effect of the CCR5 delta32/+ and CCR2b 64I/+ mutations on human immunodeficiency virus (HIV)-1 disease progression among HIV-1-infected injecting drug users. J Infect Dis 1999;179:825-831.
-
(1999)
J Infect Dis
, vol.179
, pp. 825-831
-
-
Schinkel, J.1
Langendam, M.W.2
Coutinho, R.A.3
Krol, A.4
Brouwer, M.5
Schuitemaker, H.6
-
35
-
-
0029901953
-
HIV type 1 subtypes in The Netherlands circulating among women originating from AIDS-endemic regions
-
Lukashov VV, Kuiken CL, Boer K, and Goudsmit J: HIV type 1 subtypes in The Netherlands circulating among women originating from AIDS-endemic regions. AIDS Res Hum Retroviruses 1996;12:951-953.
-
(1996)
AIDS Res Hum Retroviruses
, vol.12
, pp. 951-953
-
-
Lukashov, V.V.1
Kuiken, C.L.2
Boer, K.3
Goudsmit, J.4
-
36
-
-
0031041174
-
Founder virus population related to route of virus transmission: A determinant of intrahost human immunodeficiency virus type 1 evolution?
-
Lukashov VV and Goudsmit J: Founder virus population related to route of virus transmission: A determinant of intrahost human immunodeficiency virus type 1 evolution? J Virol 1997;71:2023-2030.
-
(1997)
J Virol
, vol.71
, pp. 2023-2030
-
-
Lukashov, V.V.1
Goudsmit, J.2
-
37
-
-
0035951494
-
Using phylogenetic analysis to trace HIV-1 migration among western European injecting drug users seroconverting from 1984 to 1997
-
Op de Coul EL, Prins M, Cornelissen M, et al.: Using phylogenetic analysis to trace HIV-1 migration among western European injecting drug users seroconverting from 1984 to 1997. AIDS 2001;15:257-266.
-
(2001)
AIDS
, vol.15
, pp. 257-266
-
-
Op de Coul, E.L.1
Prins, M.2
Cornelissen, M.3
-
39
-
-
0030757665
-
Early protective effect of CCR-5 delta 32 heterozygosity on HIV-1 disease progression: Relationship with viral load. The SEROCO Study Group
-
Meyer L, Magierowska M, Hubert JB, et al.: Early protective effect of CCR-5 delta 32 heterozygosity on HIV-1 disease progression: Relationship with viral load. The SEROCO Study Group. AIDS 1997;11:F73-78.
-
(1997)
AIDS
, vol.11
-
-
Meyer, L.1
Magierowska, M.2
Hubert, J.B.3
-
40
-
-
12144287132
-
Phenotypic and genotypic comparisons of CCR5- and CXCR4-tropic human immunodeficiency virus type 1 biological clones isolated from subtype C-infected individuals
-
Pollakis G, Abebe A, Kliphuis A, et al.: Phenotypic and genotypic comparisons of CCR5- and CXCR4-tropic human immunodeficiency virus type 1 biological clones isolated from subtype C-infected individuals. J Virol 2004;78:2841-2852.
-
(2004)
J Virol
, vol.78
, pp. 2841-2852
-
-
Pollakis, G.1
Abebe, A.2
Kliphuis, A.3
-
41
-
-
10744231634
-
Improved coreceptor usage prediction and genotypic monitoring of R5-to-X4 transition by motif analysis of human immunodeficiency virus type 1 env V3 loop sequences
-
Jensen MA, Li FS, van't Wout AB, et al.: Improved coreceptor usage prediction and genotypic monitoring of R5-to-X4 transition by motif analysis of human immunodeficiency virus type 1 env V3 loop sequences. J Virol 2003;77:13376-13388.
-
(2003)
J Virol
, vol.77
, pp. 13376-13388
-
-
Jensen, M.A.1
Li, F.S.2
van't Wout, A.B.3
-
42
-
-
0032519399
-
Differences in chemokine coreceptor usage between genetic subtypes of HIV-1
-
Tscherning C, Alaeus A, Fredriksson R, et al.: Differences in chemokine coreceptor usage between genetic subtypes of HIV-1. Virology 1998;241:181-188.
-
(1998)
Virology
, vol.241
, pp. 181-188
-
-
Tscherning, C.1
Alaeus, A.2
Fredriksson, R.3
-
43
-
-
0034690623
-
Genetic characterization of incident HIV type 1 subtype E and B strains from a prospective cohort of injecting drug users in Bangkok, Thailand
-
Subbarao S, Vanichseni S, Hu DJ, et al.: Genetic characterization of incident HIV type 1 subtype E and B strains from a prospective cohort of injecting drug users in Bangkok, Thailand. AIDS Res Hum Retroviruses 2000;16:699-707.
-
(2000)
AIDS Res Hum Retroviruses
, vol.16
, pp. 699-707
-
-
Subbarao, S.1
Vanichseni, S.2
Hu, D.J.3
-
44
-
-
0032966973
-
What role does HIV-1 subtype play in transmission and pathogenesis? An epidemiological perspective
-
Hu DJ, Buve A, Baggs J, van der Groen G, and Dondero TJ: What role does HIV-1 subtype play in transmission and pathogenesis? An epidemiological perspective. AIDS 1999;13:873-881.
-
(1999)
AIDS
, vol.13
, pp. 873-881
-
-
Hu, D.J.1
Buve, A.2
Baggs, J.3
van der Groen, G.4
Dondero, T.J.5
-
45
-
-
4544245782
-
Entry and transcription as key determinants of differences in CD4 T-cell permissiveness to human immunodeficiency virus type 1 infection
-
Ciuffi A, Bleiber G, Munoz M, et al.: Entry and transcription as key determinants of differences in CD4 T-cell permissiveness to human immunodeficiency virus type 1 infection. J Virol 2004;78:10747-10754.
-
(2004)
J Virol
, vol.78
, pp. 10747-10754
-
-
Ciuffi, A.1
Bleiber, G.2
Munoz, M.3
|