New insights into the regulation of cardiolipin biosynthesis in yeast: Implications for Barth syndrome

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1771, Issue 3, 2007, Pages 432-441

  Li, Guiling ^a   Chen, Shuliang ^a   Thompson, Morgan N ^a   Greenberg, Miriam L ^a  

^a WAYNE STATE UNIVERSITY   (United States)

Author keywords

Barth Syndrome; Cardiolipin; Mitochondrial lipid

Indexed keywords

CARDIOLIPIN; FATTY ACID; INOSITOL; MITOCHONDRIAL DNA ABSENCE SENSITIVE FACTOR; MITOCHONDRIAL PROTEIN; PHOSPHATIDYLETHANOLAMINE; PHOSPHATIDYLGLYCEROL; PHOSPHATIDYLGLYCEROLPHOSPHATE SYNTHASE; PHOSPHOLIPID; PROTEIN; TAFAZZIN; UNCLASSIFIED DRUG;

BARTH SYNDROME; BIOSYNTHESIS; CATALYSIS; ENZYME ACTIVITY; ENZYME MODIFICATION; ENZYME PHOSPHORYLATION; GENE; GENE EXPRESSION; GENE MUTATION; GOLGI COMPLEX; HUMAN; LIPID METABOLISM; LIPOGENESIS; MITOCHONDRIAL MEMBRANE; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; REVIEW; TAFAZZIN GENE; YEAST;

ACYLTRANSFERASES; ANIMALS; CARDIOLIPINS; CDPDIACYLGLYCEROL-SERINE O-PHOSPHATIDYLTRANSFERASE; GENE EXPRESSION REGULATION, FUNGAL; GENETIC DISEASES, X-LINKED; HUMANS; HYDROGEN-ION CONCENTRATION; INOSITOL; MITOCHONDRIA; PHOSPHATIDYLETHANOLAMINES; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; SYNDROME; TRANSCRIPTION FACTORS; TRANSFERASES (OTHER SUBSTITUTED PHOSPHATE GROUPS);

EID: 33947209587     PISSN: 13881981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbalip.2006.06.007     Document Type: Review

References (118)

1. Schlame M., Rua D., and Greenberg M.L. The biosynthesis and functional role of cardiolipin. Prog. Lipid Res. 39 (2000) 257-288
2. Fry M., and Green D.E. Cardiolipin requirement for electron transfer in complex I and III of the mitochondrial respiratory chain. J. Biol. Chem. 256 (1981) 1874-1880
3. Gomez Jr. B., and Robinson N.C. Phospholipase digestion of bound cardiolipin reversibly inactivates bovine cytochrome bc1. Biochemistry 38 (1999) 9031-9038
4. Schagger H., Hagen T., Roth B., Brandt U., Link T.A., and von Jagow G. Phospholipid specificity of bovine heart bc1 complex. Eur. J. Biochem. 190 (1990) 123-130
5. Yu C.A., and Yu L. Structural role of phospholipids in ubiquinol-Cytochrome c reductase. Biochemistry 19 (1980) 5715-5720
6. Hayer-Hartl M., Schagger H., von Jagow G., and Beyera K. Interactions of phospholipids with the mitochondrial cytochrome-c reductase studied by spin-label ESR and NMR spectroscopy. Eur. J. Biochem. 209 (1992) 423-430
7. Robinson N.C., Zborowski J., and Talbert L.H. Cardiolipin-depleted bovine heart cytochrome c oxidase: binding stoichiometry and affinity for cardiolipin derivatives. Biochemistry 29 (1990) 8962-8969
8. Sedlak E., and Robinson N.C. Phospholipase A(2) digestion of cardiolipin bound to bovine cytochrome c oxidase alters both activity and quaternary structure. Biochemistry 38 (1999) 14966-14972
9. Eble K.S., Coleman W.B., Hantgan R.R., and Cunningham C.C. Tightly associated cardiolipin in the bovine heart mitochondrial ATP synthase as analyzed by 31P nuclear magnetic resonance spectroscopy. J. Biol. Chem. 265 (1990) 19434-19440
10. Jiang F., Ryan M.T., Schlame M., Zhao M., Gu Z., Klingenberg M., Pfanner N., and Greenberg M.L. Absence of cardiolipin in the crd1 null mutant results in decreased mitochondrial membrane potential and reduced mitochondrial function. J. Biol. Chem. 275 (2000) 22387-22394
11. Kawasaki K., Kuge O., Chang S.C., Heacock P.N., Rho M., Suzuki K., Nishijima M., and Dowhan W. Isolation of a Chinese hamster ovary (CHO) cDNA encoding phosphatidylglycerophosphate (PGP) synthase, expression of which corrects the mitochondrial abnormalities of a PGP synthase-defective mutant of CHO-K1 cells. J. Biol. Chem. 274 (1999) 1828-1834
12. Pfeiffer K., Gohil V., Stuart R.A., Hunte C., Brandt U., Greenberg M.L., and Schagger H. Cardiolipin stabilizes respiratory chain supercomplexes. J. Biol. Chem. 278 (2003) 52873-52880
13. Zhong Q., Gohil V.M., Ma L., and Greenberg M.L. Absence of cardiolipin results in temperature sensitivity, respiratory defects, and mitochondrial DNA instability independent of pet56. J. Biol. Chem. 279 (2004) 32294-32300
14. Zhong Q., Gvozdenovic-Jeremic J., Webster P., Zhou J., and Greenberg M.L. Loss of function of KRE5 suppresses temperature sensitivity of mutants lacking mitochondrial anionic lipids. Mol. Biol. Cell 16 (2005) 665-675
15. Su X., and Dowhan W. Translational regulation of nuclear gene COX4 expression by mitochondrial content of phosphatidylglycerol and cardiolipin in Saccharomyces cerevisiae. Mol. Cell. Biol. 26 (2006) 743-753
16. Garcia Fernandez M., Troiano L., Moretti L., Nasi M., Pinti M., Salvioli S., Dobrucki J., and Cossarizza A. Early changes in intramitochondrial cardiolipin distribution during apoptosis. Cell Growth Differ. 13 (2002) 449-455
17. Garcia Fernandez M., Troiano L., Moretti L., Pedrazzi J., Salvioli S., Castilla-Cortazar I., and Cossarizza A. Changes in intramitochondrial cardiolipin distribution in apoptosis-resistant HCW-2 cells, derived from the human promyelocytic leukemia HL-60. FEBS Lett. 478 (2000) 290-294
18. Kirkland R.A., Adibhatla R.M., Hatcher J.F., and Franklin J.L. Loss of cardiolipin and mitochondria during programmed neuronal death: evidence of a role for lipid peroxidation and autophagy. Neuroscience 115 (2002) 587-602
19. Matsko C.M., Hunter O.C., Rabinowich H., Lotze M.T., and Amoscato A.A. Mitochondrial lipid alterations during Fas- and radiation-induced apoptosis. Biochem. Biophys. Res. Commun. 287 (2001) 1112-1120
20. Ostrander D.B., Sparagna G.C., Amoscato A.A., McMillin J.B., and Dowhan W. Decreased cardiolipin synthesis corresponds with cytochrome c release in palmitate-induced cardiomyocyte apoptosis. J. Biol. Chem. 276 (2001) 38061-38067
21. Vreken P., Valianpour F., Nijtmans L.G., Grivell L.A., Plecko B., Wanders R.J., and Barth P.G. Defective remodeling of cardiolipin and phosphatidylglycerol in Barth syndrome. Biochem. Biophys. Res. Commun. 279 (2000) 378-382
22. Schlame M., Towbin J.A., Heerdt P.M., Jehle R., DiMauro S., and Blanck T.J. Deficiency of tetralinoleoyl-cardiolipin in Barth syndrome. Ann. Neurol. 51 (2002) 634-637
23. Gu Z., Valianpour F., Chen S., Vaz F.M., Hakkaart G.A., Wanders R.J., and Greenberg M.L. Aberrant cardiolipin metabolism in the yeast taz1 mutant: a model for Barth syndrome. Mol. Microbiol. 51 (2004) 149-158
24. Chang S.C., Heacock P.N., Mileykovskaya E., Voelker D.R., and Dowhan W. Isolation and characterization of the gene (CLS1) encoding cardiolipin synthase in Saccharomyces cerevisiae. J. Biol. Chem. 273 (1998) 14933-14941
25. Jiang F., Rizavi H.S., and Greenberg M.L. Cardiolipin is not essential for the growth of Saccharomyces cerevisiae on fermentable or non-fermentable carbon sources. Mol. Microbiol. 26 (1997) 481-491
26. Tuller G., Hrastnik C., Achleitner G., Schiefthaler U., Klein F., and Daum G. YDL142c encodes cardiolipin synthase (Cls1p) and is non-essential for aerobic growth of Saccharomyces cerevisiae. FEBS Lett. 421 (1998) 15-18
27. Tamai K.T., and Greenberg M.L. Biochemical characterization and regulation of cardiolipin synthase in Saccharomyces cerevisiae. Biochim. Biophys. Acta 1046 (1990) 214-222
28. Schlame M., and Hostetler K.Y. Solubilization, purification, and characterization of cardiolipin synthase from rat liver mitochondria. Demonstration of its phospholipid requirement. J. Biol. Chem. 266 (1991) 22398-22403
29. Chang S.C., Heacock P.N., Clancey C.J., and Dowhan W. The PEL1 gene (renamed PGS1) encodes the phosphatidylglycero-phosphate synthase of Saccharomyces cerevisiae. J. Biol. Chem. 273 (1998) 9829-9836
30. Dzugasova V., Obernauerova M., Horvathova K., Vachova M., Zakova M., and Subik J. Phosphatidylglycerolphosphate synthase encoded by the PEL1/PGS1 gene in Saccharomyces cerevisiae is localized in mitochondria and its expression is regulated by phospholipid precursors. Curr. Genet. 34 (1998) 297-302
31. Greenberg M.L., and Lopes J.M. Genetic regulation of phospholipid biosynthesis in Saccharomyces cerevisiae. Microbiol. Rev. 60 (1996) 1-20
32. Carman G.M., and Henry S.A. Phospholipid biosynthesis in the yeast Saccharomyces cerevisiae and interrelationship with other metabolic processes. Prog. Lipid Res. 38 (1999) 361-399
33. Gaynor P.M., Hubbell S., Schmidt A.J., Lina R.A., Minskoff S.A., and Greenberg M.L. Regulation of phosphatidylglycerolphosphate synthase in Saccharomyces cerevisiae by factors affecting mitochondrial development. J. Bacteriol. 173 (1991) 6124-6131
34. Jakovcic S., Getz G.S., Rabinowitz M., Jakob H., and Swift H. Cardiolipin content of wild type and mutant yeasts in relation to mitochondrial function and development. J. Cell Biol. 48 (1971) 490-502
35. Gallet P.F., Petit J.M., Maftah A., Zachowski A., and Julien R. Asymmetrical distribution of cardiolipin in yeast inner mitochondrial membrane triggered by carbon catabolite repression. Biochem. J. 324 Pt 2 (1997) 627-634
36. Su X., and Dowhan W. Regulation of cardiolipin synthase levels in Saccharomyces cerevisiae. Yeast 23 (2006) 279-291
37. Greenberg M.L., Hubbell S., and Lam C. Inositol regulates phosphatidylglycerolphosphate synthase expression in Saccharomyces cerevisiae. Mol. Cell. Biol. 8 (1988) 4773-4779
38. Karkhoff-Schweizer R.R., Kelly B.L., and Greenberg M.L. Phosphatidylglycerolphosphate synthase expression in Schizosaccharomyces pombe is regulated by the phospholipid precursors inositol and choline. J. Bacteriol. 173 (1991) 6132-6138
39. Kelly B.L., and Greenberg M.L. Characterization and regulation of phosphatidylglycerolphosphate phosphatase in Saccharomyces cerevisiae. Biochim. Biophys. Acta 1046 (1990) 144-150
40. Zhong Q., and Greenberg M.L. Regulation of phosphatidylglycerophosphate synthase by inositol in Saccharomyces cerevisiae is not at the level of PGS1 mRNA abundance. J. Biol. Chem. 278 (2003) 33978-33984
41. He Q., and Greenberg M.L. Post-translational regulation of phosphatidylglycerolphosphate synthase in response to inositol. Mol. Microbiol. 53 (2004) 1243-1249
42. Xu F.Y., Kelly S.L., and Hatch G.M. N-Acetylsphingosine stimulates phosphatidylglycerolphosphate synthase activity in H9c2 cardiac cells. Biochem. J. 337 Pt 3 (1999) 483-490
43. Zinser E., Sperka-Gottlieb C.D., Fasch E.V., Kohlwein S.D., Paltauf F., and Daum G. Phospholipid synthesis and lipid composition of subcellular membranes in the unicellular eukaryote Saccharomyces cerevisiae. J. Bacteriol. 173 (1991) 2026-2034
44. Tuller G., Nemec T., Hrastnik C., and Daum G. Lipid composition of subcellular membranes of an FY1679-derived haploid yeast wild-type strain grown on different carbon sources. Yeast 15 (1999) 1555-1564
45. Birner R., Burgermeister M., Schneiter R., and Daum G. Roles of phosphatidylethanolamine and of its several biosynthetic pathways in Saccharomyces cerevisiae. Mol. Biol. Cell 12 (2001) 997-1007
46. Trotter P.J., Pedretti J., and Voelker D.R. Phosphatidylserine decarboxylase from Saccharomyces cerevisiae. Isolation of mutants, cloning of the gene, and creation of a null allele. J. Biol. Chem. 268 (1993) 21416-21424
47. Trotter P.J., Pedretti J., Yates R., and Voelker D.R. Phosphatidylserine decarboxylase 2 of Saccharomyces cerevisiae. Cloning and mapping of the gene, heterologous expression, and creation of the null allele. J. Biol. Chem. 270 (1995) 6071-6080
48. Saba J.D., Nara F., Bielawska A., Garrett S., and Hannun Y.A. The BST1 gene of Saccharomyces cerevisiae is the sphingosine-1-phosphate lyase. J. Biol. Chem. 272 (1997) 26087-26090
49. Mandala S.M., Thornton R., Tu Z., Kurtz M.B., Nickels J., Broach J., Menzeleev R., and Spiegel S. Sphingoid base 1-phosphate phosphatase: a key regulator of sphingolipid metabolism and stress response. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 150-155
50. Cullis P.R., and de Kruijff B. The polymorphic phase behaviour of phosphatidylethanolamines of natural and synthetic origin. A 31P NMR study. Biochim. Biophys. Acta 513 (1978) 31-42
51. Vasilenko I., De Kruijff B., and Verkleij A.J. Polymorphic phase behaviour of cardiolipin from bovine heart and from Bacillus subtilis as detected by 31P-NMR and freeze-fracture techniques. Effects of Ca2+, Mg2+, Ba2+ and temperature. Biochim. Biophys. Acta 684 (1982) 282-286
52. de Kruijff B. Lipid polymorphism and biomembrane function. Curr. Opin. Chem. Biol. 1 (1997) 564-569
53. van den Brink-van der Laan E., Killian J.A., and de Kruijff B. Nonbilayer lipids affect peripheral and integral membrane proteins via changes in the lateral pressure profile. Biochim. Biophys. Acta 1666 (2004) 275-288
54. Rietveld A.G., Killian J.A., Dowhan W., and de Kruijff B. Polymorphic regulation of membrane phospholipid composition in Escherichia coli. J. Biol. Chem. 268 (1993) 12427-12433
55. Gohil V.M., Thompson M.N., and Greenberg M.L. Synthetic lethal interaction of the mitochondrial phosphatidylethanolamine and cardiolipin biosynthetic pathways in Saccharomyces cerevisiae. J. Biol. Chem. 280 (2005) 35410-35416
56. Koshkin V., and Greenberg M.L. Oxidative phosphorylation in cardiolipin-lacking yeast mitochondria. Biochem. J. 347 Pt 3 (2000) 687-691
57. Koshkin V., and Greenberg M.L. Cardiolipin prevents rate-dependent uncoupling and provides osmotic stability in yeast mitochondria. Biochem. J. 364 (2002) 317-322
58. Zhang M., Mileykovskaya E., and Dowhan W. Cardiolipin is essential for organization of complexes III and IV into a supercomplex in intact yeast mitochondria. J. Biol. Chem. 280 (2005) 29403-29408
59. Kuchler K., Daum G., and Paltauf F. Subcellular and submitochondrial localization of phospholipid-synthesizing enzymes in Saccharomyces cerevisiae. J. Bacteriol. 165 (1986) 901-910
60. Zhao M., Schlame M., Rua D., and Greenberg M.L. Cardiolipin synthase is associated with a large complex in yeast mitochondria. J. Biol. Chem. 273 (1998) 2402-2408
61. Gohil V.M., Hayes P., Matsuyama S., Schagger H., Schlame M., and Greenberg M.L. Cardiolipin biosynthesis and mitochondrial respiratory chain function are interdependent. J. Biol. Chem. 279 (2004) 42612-42618
62. Frentzen M., and Griebau R. Biosynthesis of cardiolipin in plant mitochondria. Plant Physiol. 106 (1994) 1527-1532
63. Kroemer G., and Reed J.C. Mitochondrial control of cell death. Nat. Med. 6 (2000) 513-519
64. Green D.R., and Kroemer G. The pathophysiology of mitochondrial cell death. Science 305 (2004) 626-629
65. Kowaltowski A.J., and Vercesi A.E. Mitochondrial damage induced by conditions of oxidative stress. Free Radic. Biol. Med. 26 (1999) 463-471
66. Cortopassi G.A., and Wong A. Mitochondria in organismal aging and degeneration. Biochim. Biophys. Acta 1410 (1999) 183-193
67. Melov S. Mitochondrial oxidative stress. Physiologic consequences and potential for a role in aging. Ann. N.Y. Acad. Sci. 908 (2000) 219-225
68. Attardi G., and Schatz G. Biogenesis of mitochondria. Annu. Rev. Cell Biol. 4 (1988) 289-333
69. Yaffe M.P. The machinery of mitochondrial inheritance and behavior. Science 283 (1999) 1493-1497
70. Collins T.J., Berridge M.J., Lipp P., and Bootman M.D. Mitochondria are morphologically and functionally heterogeneous within cells. EMBO J. 21 (2002) 1616-1627
71. Nisoli E., Falcone S., Tonello C., Cozzi V., Palomba L., Fiorani M., Pisconti A., Brunelli S., Cardile A., Francolini M., Cantoni O., Carruba M.O., Moncada S., and Clementi E. Mitochondrial biogenesis by NO yields functionally active mitochondria in mammals. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 16507-16512
72. Brunk C.F. Mitochondrial proliferation during myogenesis. Exp. Cell Res. 136 (1981) 305-309
73. Moyes C.D., Mathieu-Costello O.A., Tsuchiya N., Filburn C., and Hansford R.G. Mitochondrial biogenesis during cellular differentiation. Am. J. Physiol. 272 (1997) C1345-C1351
74. Schon E.A. Mitochondrial genetics and disease. Trends Biochem. Sci. 25 (2000) 555-560
75. Wallace D.C. Mitochondrial diseases in man and mouse. Science 283 (1999) 1482-1488
76. Butow R.A., and Avadhani N.G. Mitochondrial signaling: the retrograde response. Mol. Cell 14 (2004) 1-15
77. Garesse R., and Vallejo C.G. Animal mitochondrial biogenesis and function: a regulatory cross-talk between two genomes. Gene 263 (2001) 1-16
78. MacAlpine D.M., Perlman P.S., and Butow R.A. The numbers of individual mitochondrial DNA molecules and mitochondrial DNA nucleoids in yeast are co-regulated by the general amino acid control pathway. EMBO J. 19 (2000) 767-775
79. Jazwinski S.M. Yeast longevity and aging-The mitochondrial connection. Mech. Ageing Dev. 126 (2005) 243-248
80. Nakashima-Kamimura N., Asoh S., Ishibashi Y., Mukai Y., Shidara Y., Oda H., Munakata K., Goto Y., and Ohta S. MIDAS/GPP34, a nuclear gene product, regulates total mitochondrial mass in response to mitochondrial dysfunction. J. Cell Sci. 118 (2005) 5357-5367
81. Schlame M., Beyer K., Hayer-Hartl M., and Klingenberg M. Molecular species of cardiolipin in relation to other mitochondrial phospholipids. Is there an acyl specificity of the interaction between cardiolipin and the ADP/ATP carrier?. Eur. J. Biochem. 199 (1991) 459-466
82. Schlame M., Ren M., Xu Y., Greenberg M.L., and Haller I. Molecular symmetry in mitochondrial cardiolipins. Chem. Phys. Lipids 138 (2005) 38-49
83. Nomura K., Imai H., Koumura T., Kobayashi T., and Nakagawa Y. Mitochondrial phospholipid hydroperoxide glutathione peroxidase inhibits the release of cytochrome c from mitochondria by suppressing the peroxidation of cardiolipin in hypoglycaemia-induced apoptosis. Biochem. J. 351 (2000) 183-193
84. Shidoji Y., Hayashi K., Komura S., Ohishi N., and Yagi K. Loss of molecular interaction between cytochrome c and cardiolipin due to lipid peroxidation. Biochem. Biophys. Res. Commun. 264 (1999) 343-347
85. Barth P.G., Scholte H.R., Berden J.A., Van der Klei-Van Moorsel J.M., Luyt-Houwen I.E., Van 't Veer-Korthof E.T., Van der Harten J.J., and Sobotka-Plojhar M.A. An X-linked mitochondrial disease affecting cardiac muscle, skeletal muscle and neutrophil leucocytes. J. Neurol. Sci. 62 (1983) 327-355
86. Barth P.G., Van den Bogert C., Bolhuis P.A., Scholte H.R., van Gennip A.H., Schutgens R.B., and Ketel A.G. X-linked cardioskeletal myopathy and neutropenia (Barth syndrome): respiratory-chain abnormalities in cultured fibroblasts. J. Inherit. Metab. Dis. 19 (1996) 157-160
87. Bolhuis P.A., Hensels G.W., Hulsebos T.J., Baas F., and Barth P.G. Mapping of the locus for X-linked cardioskeletal myopathy with neutropenia and abnormal mitochondria (Barth syndrome) to Xq28. Am. J. Hum. Genet. 48 (1991) 481-485
88. Bione S., D'Adamo P., Maestrini E., Gedeon A.K., Bolhuis P.A., and Toniolo D. A novel X-linked gene, G4.5. is responsible for Barth syndrome. Nat. Genet. 12 (1996) 385-389
89. Neuwald A.F. Barth syndrome may be due to an acyltransferase deficiency. Curr. Biol. 7 (1997) R465-R466
90. Valianpour F., Wanders R.J., Barth P.G., Overmars H., and van Gennip A.H. Quantitative and compositional study of cardiolipin in platelets by electrospray ionization mass spectrometry: application for the identification of Barth syndrome patients. Clin. Chem. 48 (2002) 1390-1397
91. de Winter J.M., Lenting H.B., Neys F.W., and van den Bosch H. Hydrolysis of membrane-associated phosphoglycerides by mitochondrial phospholipase A2. Biochim. Biophys. Acta 917 (1987) 169-177
92. Hostetler K.Y., Galesloot J.M., Boer P., and Van Den Bosch H. Further studies on the formation of cardiolipin and phosphatidylglycerol in rat liver mitochondria. Effect of divalent cations and the fatty acid composition of CDP-diglyceride. Biochim. Biophys. Acta 380 (1975) 382-389
93. Rustow B., Schlame M., Rabe H., Reichmann G., and Kunze D. Species pattern of phosphatidic acid, diacylglycerol, CDP-diacylglycerol and phosphatidylglycerol synthesized de novo in rat liver mitochondria. Biochim. Biophys. Acta 1002 (1989) 261-263
94. Schlame M., and Rustow B. Lysocardiolipin formation and reacylation in isolated rat liver mitochondria. Biochem. J. 272 (1990) 589-595
95. Ma B.J., Taylor W.A., Dolinsky V.W., and Hatch G.M. Acylation of monolysocardiolipin in rat heart. J. Lipid Res. 40 (1999) 1837-1845
96. Hoffmann B., Stockl A., Schlame M., Beyer K., and Klingenberg M. The reconstituted ADP/ATP carrier activity has an absolute requirement for cardiolipin as shown in cysteine mutants. J. Biol. Chem. 269 (1994) 1940-1944
97. Paradies G., Petrosillo G., and Ruggiero F.M. Cardiolipin-dependent decrease of cytochrome c oxidase activity in heart mitochondria from hypothyroid rats. Biochim. Biophys. Acta 1319 (1997) 5-8
98. Taylor W.A., and Hatch G.M. Purification and characterization of monolysocardiolipin acyltransferase from pig liver mitochondria. J. Biol. Chem. 278 (2003) 12716-12721
99. Taylor W.A., Xu F.Y., Ma B.J., Mutter T.C., Dolinsky V.W., and Hatch G.M. Expression of monolysocardiolipin acyltransferase activity is regulated in concert with the level of cardiolipin and cardiolipin biosynthesis in the mammalian heart. BMC Biochem. 3 (2002) 9
100. Cao J., Liu Y., Lockwood J., Burn P., and Shi Y. A novel cardiolipin-remodeling pathway revealed by a gene encoding an endoplasmic reticulum-associated acyl-CoA:lysocardiolipin acyltransferase (ALCAT1) in mouse. J. Biol. Chem. 279 (2004) 31727-31734
101. Xu Y., Kelley R.I., Blanck T.J., and Schlame M. Remodeling of cardiolipin by phospholipid transacylation. J. Biol. Chem. 278 (2003) 51380-51385
102. Xu Y., Sutachan J.J., Plesken H., Kelley R.I., and Schlame M. Characterization of lymphoblast mitochondria from patients with Barth syndrome. Lab. Invest. 85 (2005) 823-830
103. Valianpour F., Wanders R.J., Overmars H., Vaz F.M., Barth P.G., and van Gennip A.H. Linoleic acid supplementation of Barth syndrome fibroblasts restores cardiolipin levels: implications for treatment. J. Lipid Res. 44 (2003) 560-566
104. Valianpour F., Vreken P., Nijtmans L.G., van Roermund C.W.T., Grivell L.A., Wanders R.J., and Barth P.G. Investigation of defective cardiolipin remodeling in Barth syndrome using yeast as study model (Abstract). J. Inherit. Metab. Dis. 24 (2001) 83
105. Ma L., Vaz F.M., Gu Z., Wanders R.J., and Greenberg M.L. The human TAZ gene complements mitochondrial dysfunction in the yeast taz1Delta mutant. Implications for Barth syndrome. J. Biol. Chem. 279 (2004) 44394-44399
106. Vaz F.M., Houtkooper R.H., Valianpour F., Barth P.G., and Wanders R.J. Only one splice variant of the human TAZ gene encodes a functional protein with a role in cardiolipin metabolism. J. Biol. Chem. 278 (2003) 43089-43094
107. Schlame M., Kelley R.I., Feigenbaum A., Towbin J.A., Heerdt P.M., Schieble T., Wanders R.J., DiMauro S., and Blanck T.J. Phospholipid abnormalities in children with Barth syndrome. J. Am. Coll. Cardiol. 42 (2003) 1994-1999
108. Testet E., Laroche-Traineau J., Noubhani A., Coulon D., Bunoust O., Camougrand N., Manon S., Lessire R., and Bessoule J.J. Ypr140wp, 'the yeast tafazzin', displays a mitochondrial lysophosphatidylcholine (lyso-PC) acyltransferase activity related to triacylglycerol and mitochondrial lipid synthesis. Biochem. J. 387 (2005) 617-626
109. Chi Z., and Arneborg N. Relationship between lipid composition, frequency of ethanol-induced respiratory deficient mutants, and ethanol tolerance in Saccharomyces cerevisiae. J. Appl. Microbiol. 86 (1999) 1047-1052
110. You K.M., Rosenfield C.L., and Knipple D.C. Ethanol tolerance in the yeast Saccharomyces cerevisiae is dependent on cellular oleic acid content. Appl. Environ. Microbiol. 69 (2003) 1499-1503
111. Brandner K., Mick D.U., Frazier A.E., Taylor R.D., Meisinger C., and Rehling P. Taz1, an outer mitochondrial membrane protein, affects stability and assembly of inner membrane protein complexes: implications for Barth Syndrome. Mol. Biol. Cell 16 (2005) 5202-5214
112. Dietmeier K., Honlinger A., Bomer U., Dekker P.J., Eckerskorn C., Lottspeich F., Kubrich M., and Pfanner N. Tom5 functionally links mitochondrial preprotein receptors to the general import pore. Nature 388 (1997) 195-200
113. Schmitt S., Ahting U., Eichacker L., Granvogl B., Go N.E., Nargang F.E., Neupert W., and Nussberger S. Role of Tom5 in maintaining the structural stability of the TOM complex of mitochondria. J. Biol. Chem. 280 (2005) 14499-14506
114. Koehler C.M., Merchant S., Oppliger W., Schmid K., Jarosch E., Dolfini L., Junne T., Schatz G., and Tokatlidis K. Tim9p, an essential partner subunit of Tim10p for the import of mitochondrial carrier proteins. EMBO J. 17 (1998) 6477-6486
115. Davey K.M., Parboosingh J.S., McLeod D.R., Chan A., Casey R., Ferreira P., Snyder F.F., Bridge P.J., and Bernier F.P. Mutation of DNAJC19, a human homolog of yeast inner mitochondrial membrane co-chaperones, causes DCMA syndrome, a novel autosomal recessive Barth syndrome-like condition. J. Med. Genet. (2005)
116. Mokranjac D., Sichting M., Neupert W., and Hell K. Tim14, a novel key component of the import motor of the TIM23 protein translocase of mitochondria. EMBO J. 22 (2003) 4945-4956
117. Clark J.D., Milona N., and Knopf J.L. Purification of a 110-kilodalton cytosolic phospholipase A2 from the human monocytic cell line U937. Proc. Natl. Acad. Sci. U. S. A. 87 (1990) 7708-7712
118. Reers M., and Pfeiffer D.R. Inhibition of mitochondrial phospholipase A2 by mono- and dilysocardiolipin. Biochemistry 26 (1987) 8038-8041