Effect of cell-density on in-vitro dopaminergic differentiation of mesencephalic precursor cells

NeuroReport

Volumn 16, Issue 5, 2005, Pages 499-503

  Ko, Ji Yun ^a,b   Lee, Ji Yeon ^a,b   Park, Chang Hwan ^b   Lee, Sang Hun ^a,b  

^a Department of Biochemistry ^*  (South Korea)

^b Hanyang University   (South Korea)

Author keywords

Cell density; Differentiation; Dopamine neuron; In vitro expansion; Neural precursor cell; Neural stem cell; Soluble factors

Indexed keywords

CELL MARKER;

ANIMAL CELL; ARTICLE; CELL CONTACT; CELL COUNT; CELL DENSITY; COCULTURE; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; EMBRYO; MESENCEPHALON; NERVE CELL CULTURE; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NONHUMAN; PLATING MEDIUM; PRIORITY JOURNAL; PROTEIN SECRETION; RAT; TIME;

EID: 16444372503     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001756-200504040-00016     Document Type: Article

References (14)

1. Graybiel AM, Aosaki T, Flaherty AW, Kimura M. The basal ganglia and adaptive motor control. Science 1994; 265:1826-1831.
2. Berke JD, Hyman SE. Addiction, dopamine, and the molecular mechanisms of memory. Neuron 2000; 25:515-532.
3. Nieoullon A. Dopamine and the regulation of cognition and attention. Prog Neurobiol 2002; 67:53-83.
4. Piccini P, Brooks DJ, Bjorklund A, Gunn RN, Grasby PM, Rimoldi O et al. Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient. Nature Neurosci 1999; 2:1137-1140.
5. Studer L, Tabar V, McKay RD. Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats. Nat Neurosci 1998; 1:290-295.
6. McKay RD. Stem cells in the central nervous system. Science 1997; 276:66-71.
7. Tsai RY, McKay RD. Cell contact regulates fate choice by cortical stem cells. J Neurosci 2000; 20:3725-3735.
8. Chang MY, Park CH, Lee SY, Lee SH. Properties of cortical precursor cells cultured long term are similar to those of precursors at later developmental stages. Brain Res Dev Brain Res 2004; 153:89-96.
9. Chang MY, Park CH, Lee SH. Embryonic cortical stem cells secrete diffusible factors to enhance their survival. Neuroreport 2004; 14:1191-1195.
10. Chang MY, Son H, Lee YS, Lee SH. Neurons and astrocytes secrete factors that cause stem cells to differentiate into neurons and astrocytes, respectively. Mol Cell Neurosci 2003; 23:414-426.
11. McConnell SK, Kaznowski CE. Cell cycle dependence of laminar determination in developing neocortex. Science 1991; 254:282-285.
12. Yan J, Studer L, McKay RD. Ascorbic acid increases the yield of dopaminergic neurons derived from basic fibroblast growth factor expanded mesencephalic precursors. J Neurochem 2001; 76:307-311.
13. Taupin P, Ray J, Fischer WH, Suhr ST, Hakansson K, Grubb A et al. FGF-2-responsive neural stem cell proliferation requires CCg, a novel autocrine/paracrine cofactor. Neuron 2000; 28:385-397.
14. Qian X, Shen Q, Goderie SK, He W, Capela A, Davis AA et al. Timing of CNS cell generation: a programmed sequence of neuron and glial cell production from isolated murine cortical stem cells. Neuron 2000; 28:69-80.