메뉴 건너뛰기




Volumn 26, Issue 11, 2007, Pages 1595-1605

Identification of a new class of PAX3-FKHR target promoters: A role of the Pax3 paired box DNA binding domain

Author keywords

Chromosomal translocation; Oncogene; Rhabdomyosarcoma; Transcription

Indexed keywords

MYOGENIN; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR PAX3;

EID: 33947158748     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1209958     Document Type: Article
Times cited : (30)

References (39)
  • 1
    • 0034853327 scopus 로고    scopus 로고
    • Embryonic expression of the tumor-associated PAX3-FKHR fusion protein interferes with the developmental functions of Pax3
    • Anderson J, Ramsay A, Gould S, Pritchard-Jones K. (2001). Embryonic expression of the tumor-associated PAX3-FKHR fusion protein interferes with the developmental functions of Pax3. Am J Path 159: 1089-1096.
    • (2001) Am J Path , vol.159 , pp. 1089-1096
    • Anderson, J.1    Ramsay, A.2    Gould, S.3    Pritchard-Jones, K.4
  • 2
    • 0030999729 scopus 로고    scopus 로고
    • Fusions involving paired box and fork head family transcription factors in the pediatric cancer alveolar rhabdomyosarcoma
    • Barr FG. (1997). Fusions involving paired box and fork head family transcription factors in the pediatric cancer alveolar rhabdomyosarcoma. Curr Topics Micro Immun 220: 113-129.
    • (1997) Curr Topics Micro Immun , vol.220 , pp. 113-129
    • Barr, F.G.1
  • 3
    • 0027534945 scopus 로고
    • Rearrangement of the PAX3 paired box gene in the paediatric solid tumour alveolar rhabdomyosarcoma
    • Barr FG, Galili N, Holick J, Biegel JA, Rovera G, Emanuel BS. (1993). Rearrangement of the PAX3 paired box gene in the paediatric solid tumour alveolar rhabdomyosarcoma. Nat Genet 3: 113-117.
    • (1993) Nat Genet , vol.3 , pp. 113-117
    • Barr, F.G.1    Galili, N.2    Holick, J.3    Biegel, J.A.4    Rovera, G.5    Emanuel, B.S.6
  • 4
    • 16244385890 scopus 로고    scopus 로고
    • Cell-type-specific regulation of distinct sets of gene targets by Pax3 and Pax3/FKHR
    • Begum S, Emani N, Cheung A, Wilkins O, Der S, Hamel PA. (2005). Cell-type-specific regulation of distinct sets of gene targets by Pax3 and Pax3/FKHR. Oncogene 24: 1860-1872.
    • (2005) Oncogene , vol.24 , pp. 1860-1872
    • Begum, S.1    Emani, N.2    Cheung, A.3    Wilkins, O.4    Der, S.5    Hamel, P.A.6
  • 6
    • 0028287953 scopus 로고
    • The myogenin gene is activated during myocyte differentiation by pre-existing, not newly synthesized transcription factor MEF-2
    • Buchberger A, Ragge K, Arnold HH. (1994). The myogenin gene is activated during myocyte differentiation by pre-existing, not newly synthesized transcription factor MEF-2. J Biol Chem 269: 17289-17296.
    • (1994) J Biol Chem , vol.269 , pp. 17289-17296
    • Buchberger, A.1    Ragge, K.2    Arnold, H.H.3
  • 7
    • 0034737605 scopus 로고    scopus 로고
    • The COOH-terminal transactivation domain plays a key role in regulating the in vitro and in vivo function of Pax3 homeodomain
    • Cao Y, Wang C. (2000). The COOH-terminal transactivation domain plays a key role in regulating the in vitro and in vivo function of Pax3 homeodomain. J Biol Chem 275: 9854-9862.
    • (2000) J Biol Chem , vol.275 , pp. 9854-9862
    • Cao, Y.1    Wang, C.2
  • 9
    • 0028587375 scopus 로고
    • Pax-3 contains domains for transcription activation and transcription inhibition
    • Chalepakis G, Jones FS, Eelman GM, Gruss P. (1994b). Pax-3 contains domains for transcription activation and transcription inhibition. Proc Natl Acad Sci USA 91: 12745-12749.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 12745-12749
    • Chalepakis, G.1    Jones, F.S.2    Eelman, G.M.3    Gruss, P.4
  • 10
    • 0029151172 scopus 로고
    • Identification of DNA recognition sequences for the Pax3 paired domain
    • Chalepakis G, Gruss P. (1995). Identification of DNA recognition sequences for the Pax3 paired domain. Gene 162: 267-270.
    • (1995) Gene , vol.162 , pp. 267-270
    • Chalepakis, G.1    Gruss, P.2
  • 11
    • 0027098031 scopus 로고
    • Mapping of myogenin transcription during embryogenesis using transgenes linked to the myogenin control region
    • Cheng TC, Hanley TA, Mudd J, Merlie JP, Olson EN. (1992). Mapping of myogenin transcription during embryogenesis using transgenes linked to the myogenin control region. J Cell Biol 119: 1649-1656.
    • (1992) J Cell Biol , vol.119 , pp. 1649-1656
    • Cheng, T.C.1    Hanley, T.A.2    Mudd, J.3    Merlie, J.P.4    Olson, E.N.5
  • 12
    • 0027226234 scopus 로고
    • Separable regulatory elements governing myogenin transcription in mouse embryogenesis
    • Cheng TC, Wallace MC, Merlie JP, Olson E.N. (1993). Separable regulatory elements governing myogenin transcription in mouse embryogenesis. Science 261: 215-218.
    • (1993) Science , vol.261 , pp. 215-218
    • Cheng, T.C.1    Wallace, M.C.2    Merlie, J.P.3    Olson, E.N.4
  • 13
    • 33646382114 scopus 로고    scopus 로고
    • Gene expression profiling identifies potential relevant genes in alveolar rhabdomyosarcoma pathogenesis and discriminates PAX3-FKHR positive and negative tumors
    • De Pitta C, Tombolan L, Albiero G, Sartori F, Romualdi C, Jurman G et al. (2006). Gene expression profiling identifies potential relevant genes in alveolar rhabdomyosarcoma pathogenesis and discriminates PAX3-FKHR positive and negative tumors. Int J Cancer 118: 2772-2781.
    • (2006) Int J Cancer , vol.118 , pp. 2772-2781
    • De Pitta, C.1    Tombolan, L.2    Albiero, G.3    Sartori, F.4    Romualdi, C.5    Jurman, G.6
  • 14
    • 0033888976 scopus 로고    scopus 로고
    • Strong immunostaining for myogenin in rhabdomyosarcoma is significantly associated with tumors of the alveolar subclass
    • Dias P, Chen B, Dilday B, Palmer H, Hosoi H, Singh S et al. (2000). Strong immunostaining for myogenin in rhabdomyosarcoma is significantly associated with tumors of the alveolar subclass. Am J Path 156: 399-408.
    • (2000) Am J Path , vol.156 , pp. 399-408
    • Dias, P.1    Chen, B.2    Dilday, B.3    Palmer, H.4    Hosoi, H.5    Singh, S.6
  • 16
    • 0029074993 scopus 로고
    • Pax3 inhibits myogenic differentiation of cultured myoblast cells
    • Epstein JA, Lam P, Jepeal L, Maas RL, Shapiro DN. (1995). Pax3 inhibits myogenic differentiation of cultured myoblast cells. J Biol Chem 270: 11719-11722.
    • (1995) J Biol Chem , vol.270 , pp. 11719-11722
    • Epstein, J.A.1    Lam, P.2    Jepeal, L.3    Maas, R.L.4    Shapiro, D.N.5
  • 17
    • 0031861728 scopus 로고    scopus 로고
    • Tumor-specific PAX3-FKHR transcription factor, but not PAX3, activates the platelet-derived growth factor alpha receptor
    • Epstein JA, Song B, Lakkis M, Wang C. (1998). Tumor-specific PAX3-FKHR transcription factor, but not PAX3, activates the platelet-derived growth factor alpha receptor. Mol Cell Biol 18: 4118-4130.
    • (1998) Mol Cell Biol , vol.18 , pp. 4118-4130
    • Epstein, J.A.1    Song, B.2    Lakkis, M.3    Wang, C.4
  • 18
    • 0036584242 scopus 로고    scopus 로고
    • MyoD1 and myogenin expression in human neoplasia: A review and update
    • Folpe AL. (2002). MyoD1 and myogenin expression in human neoplasia: a review and update. Adv Anat Path 9: 198-203.
    • (2002) Adv Anat Path , vol.9 , pp. 198-203
    • Folpe, A.L.1
  • 19
    • 0028881603 scopus 로고
    • The PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3
    • Fredericks WJ, Galili N, Mukhopadhyay S, Rovera G, Bennicelli J, Barr FG et al. (1995). The PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3. Mol Cell Biol 15: 1522-1535.
    • (1995) Mol Cell Biol , vol.15 , pp. 1522-1535
    • Fredericks, W.J.1    Galili, N.2    Mukhopadhyay, S.3    Rovera, G.4    Bennicelli, J.5    Barr, F.G.6
  • 20
    • 0025875226 scopus 로고
    • Pax3, a novel murine DNA binding proein expressed duringearly neurogeneisis
    • Goulding MD, Chalepakis G, Deutsch U, Erselius JR, Gruss P. (1991). Pax3, a novel murine DNA binding proein expressed duringearly neurogeneisis. EMBO J 10: 1135-1147.
    • (1991) EMBO J , vol.10 , pp. 1135-1147
    • Goulding, M.D.1    Chalepakis, G.2    Deutsch, U.3    Erselius, J.R.4    Gruss, P.5
  • 21
    • 10044288449 scopus 로고    scopus 로고
    • Rhabdomyosarcoma: Value of myogenin expression analysis and molecular testing in diagnosing the alveolar subtype: an analysis of 109 paraffin-embedded specimens
    • Hostein I, Andraud-Fregeville M, Guillou L, Terrier-Lacombe MJ, Deminiere C, Ranchere D et al. (2004). Rhabdomyosarcoma: value of myogenin expression analysis and molecular testing in diagnosing the alveolar subtype: an analysis of 109 paraffin-embedded specimens. Cancer 101: 2817-2824.
    • (2004) Cancer , vol.101 , pp. 2817-2824
    • Hostein, I.1    Andraud-Fregeville, M.2    Guillou, L.3    Terrier-Lacombe, M.J.4    Deminiere, C.5    Ranchere, D.6
  • 22
    • 0026765031 scopus 로고
    • Overexpression of Id protein inhibits the muscle differentiation program: In vivo association of Id with E2A proteins
    • Jen Y, Weintraub H, Benezra R. (1992). Overexpression of Id protein inhibits the muscle differentiation program: in vivo association of Id with E2A proteins. Genes Dev 6: 1466-1479.
    • (1992) Genes Dev , vol.6 , pp. 1466-1479
    • Jen, Y.1    Weintraub, H.2    Benezra, R.3
  • 23
    • 7544243041 scopus 로고    scopus 로고
    • Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: Cooperativity of Ink4a/ARF and Trp53 loss of function
    • Keller C, Arenkiel BR, Coffin CM, El-Bardeesy N, DePinho RA, Capecchi MR. (2004a). Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function. Genes Dev 18: 2614-2626.
    • (2004) Genes Dev , vol.18 , pp. 2614-2626
    • Keller, C.1    Arenkiel, B.R.2    Coffin, C.M.3    El-Bardeesy, N.4    DePinho, R.A.5    Capecchi, M.R.6
  • 24
    • 7544235883 scopus 로고    scopus 로고
    • Pax3:Fkhr interferes with embryonic Pax3 and Pax7 function: Implications for alveolar rhabdomyosarcoma cell of origin
    • Keller C, Hansen MS, Coffin CM, Capecchi MR. (2004b). Pax3:Fkhr interferes with embryonic Pax3 and Pax7 function: implications for alveolar rhabdomyosarcoma cell of origin. Genes Dev 18: 2608-2613.
    • (2004) Genes Dev , vol.18 , pp. 2608-2613
    • Keller, C.1    Hansen, M.S.2    Coffin, C.M.3    Capecchi, M.R.4
  • 25
    • 0033539498 scopus 로고    scopus 로고
    • cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene
    • Khan J, Bittner ML, Sall LH, Teichmann U, Azorsa DO, Gooden GC et al. (1999). cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene. Proc Natl Acad Sci USA 96: 13264-13269.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 13264-13269
    • Khan, J.1    Bittner, M.L.2    Sall, L.H.3    Teichmann, U.4    Azorsa, D.O.5    Gooden, G.C.6
  • 26
    • 0032906216 scopus 로고    scopus 로고
    • The oncogenic potential of the PAX3-FKHR fusion protein requires the Pax3 homeodomain recognition helix but not the Pax3 paired-Box DNA binding domain
    • Lam PYP, Sublett JE, Hollenbach AD, Roussel MF. (1999). The oncogenic potential of the PAX3-FKHR fusion protein requires the Pax3 homeodomain recognition helix but not the Pax3 paired-Box DNA binding domain. Mol Cell Biol 19: 594-601.
    • (1999) Mol Cell Biol , vol.19 , pp. 594-601
    • Lam, P.Y.P.1    Sublett, J.E.2    Hollenbach, A.D.3    Roussel, M.F.4
  • 27
    • 0029054218 scopus 로고
    • The role of the CANNTG promoter element (E box) and the myocyte-enhancer-binding-factor-2 (MEF-2) site in the transcriptional regulation of the chick myogenin gene
    • Malik S, Huang CF, Schmidt J. (1995). The role of the CANNTG promoter element (E box) and the myocyte-enhancer-binding-factor-2 (MEF-2) site in the transcriptional regulation of the chick myogenin gene. Eur J Biochem 230: 88-96.
    • (1995) Eur J Biochem , vol.230 , pp. 88-96
    • Malik, S.1    Huang, C.F.2    Schmidt, J.3
  • 29
    • 0034162714 scopus 로고    scopus 로고
    • Induction of terminal differentiation by constitutive activation of p38 MAP kinase in human rhabdomyosarcoma cells
    • Puri PL, Wu Z, Zhang P, Wood LD, Bhakta KS, Han J et al. (2000). Induction of terminal differentiation by constitutive activation of p38 MAP kinase in human rhabdomyosarcoma cells. Genes Dev 14: 574-584.
    • (2000) Genes Dev , vol.14 , pp. 574-584
    • Puri, P.L.1    Wu, Z.2    Zhang, P.3    Wood, L.D.4    Bhakta, K.S.5    Han, J.6
  • 30
    • 0029796402 scopus 로고    scopus 로고
    • The hybrid PAX3-FKHR fusion protein of alveolar rhabdomyosarcoma transforms fibroblasts in culture
    • Scheidler S, Fredericks WJ, Rauscher JF, Barr GF, Vogt PK. (1996). The hybrid PAX3-FKHR fusion protein of alveolar rhabdomyosarcoma transforms fibroblasts in culture. Proc Natl Acad Sci USA 93: 9805-9809.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 9805-9809
    • Scheidler, S.1    Fredericks, W.J.2    Rauscher, J.F.3    Barr, G.F.4    Vogt, P.K.5
  • 31
    • 0027366917 scopus 로고
    • Fusion of PAX3 to a member of the Forkhead family of transcripton factors in human alveolar rhabdomyosarcoma
    • Shapiro DN, Sublett JE, Li B, Downing JR, Naeve CW. (1993). Fusion of PAX3 to a member of the Forkhead family of transcripton factors in human alveolar rhabdomyosarcoma. Cancer Res 53: 5108-5112.
    • (1993) Cancer Res , vol.53 , pp. 5108-5112
    • Shapiro, D.N.1    Sublett, J.E.2    Li, B.3    Downing, J.R.4    Naeve, C.W.5
  • 32
    • 0029890899 scopus 로고    scopus 로고
    • Inhibition of myogenic bHLH and MEF2 transcription factors by the bHLH protein Twist
    • Spicer DB, Rhee J, Cheung WL, Lassar AB. (1996). Inhibition of myogenic bHLH and MEF2 transcription factors by the bHLH protein Twist. Science 272: 1476-1480.
    • (1996) Science , vol.272 , pp. 1476-1480
    • Spicer, D.B.1    Rhee, J.2    Cheung, W.L.3    Lassar, A.B.4
  • 33
    • 0032564423 scopus 로고    scopus 로고
    • Expression of myogenin during embryogenesis is controlled by Six/sine oculis homeoproteins through a conserved MEF3 binding site
    • Spitz F, Demignon J, Porteu A, Kahn A, Concordet JP, Daegelen D et al. (1998). Expression of myogenin during embryogenesis is controlled by Six/sine oculis homeoproteins through a conserved MEF3 binding site. Proc Natl Acad Sci USA 95: 14220-14225.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 14220-14225
    • Spitz, F.1    Demignon, J.2    Porteu, A.3    Kahn, A.4    Concordet, J.P.5    Daegelen, D.6
  • 34
    • 0027414452 scopus 로고
    • Deficiency in rhabdomyosarcomas of a factor required for MyoD activity and myogenesis
    • Tapscott SJ, Thayer MJ, Weintraub H. (1993). Deficiency in rhabdomyosarcomas of a factor required for MyoD activity and myogenesis. Science 259: 1450-1453.
    • (1993) Science , vol.259 , pp. 1450-1453
    • Tapscott, S.J.1    Thayer, M.J.2    Weintraub, H.3
  • 37
    • 0031398487 scopus 로고    scopus 로고
    • Disruption of the MyoD/p21 pathway in rhabdomyosarcoma
    • Weintraub M, Kalebic T, Helman JL, Bhatia GK. (1997). Disruption of the MyoD/p21 pathway in rhabdomyosarcoma. Sarcoma 1: 135-141.
    • (1997) Sarcoma , vol.1 , pp. 135-141
    • Weintraub, M.1    Kalebic, T.2    Helman, J.L.3    Bhatia, G.K.4
  • 38
    • 0027227469 scopus 로고
    • The regulation of myogenin gene expression during the embryonic development of the mouse
    • Yee SP, Rigby PW. (1993). The regulation of myogenin gene expression during the embryonic development of the mouse. Genes Dev 7: 1277-1289.
    • (1993) Genes Dev , vol.7 , pp. 1277-1289
    • Yee, S.P.1    Rigby, P.W.2
  • 39
    • 33646356739 scopus 로고    scopus 로고
    • F-box protein Skp2: A novel transcriptional target of E2F
    • Zhang L, Wang C. (2006). F-box protein Skp2: a novel transcriptional target of E2F. Oncogene 25: 2615-2627.
    • (2006) Oncogene , vol.25 , pp. 2615-2627
    • Zhang, L.1    Wang, C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.