A Thermoanaerobacter ethanolicus secondary alcohol dehydrogenase mutant derivative highly active and stereoselective on phenylacetone and benzylacetone

Protein Engineering, Design and Selection

Volumn 20, Issue 2, 2007, Pages 47-55

  Ziegelmann Fjeld, Karla I ^a   Musa, Musa M ^b   Phillips, Robert S ^b   Zeikus, J Gregory ^a   Vieille, Claire ^a  

^a Michigan State University   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

Author keywords

(S) alcohol; Benzylacetone; Enantioselectivity; Phenylacetone; Secondary alcohol dehydrogenase

Indexed keywords

BENZYLACETONE; PHENYLACETONE; SECONDARY ALCOHOL DEHYDROGENASE; TERNARY ENZYMES;

ACETONE; BACTERIA; BUTENES; DRUG PRODUCTS; ENANTIOSELECTIVITY; MUTAGENESIS;

ENZYME ACTIVITY;

1 PHENYL 2 PROPANOL; 2 BUTANOL; 4 BROMOBENZYL ALCOHOL; ACETONE; ALCOHOL DEHYDROGENASE; ALCOHOL DERIVATIVE; BENZYLACETONE; FUNCTIONAL GROUP; LIVER ENZYME; NICOTINAMIDE ADENINE DINUCLEOTIDE; PHENYLACETONE; UNCLASSIFIED DRUG;

ARTICLE; BIOENGINEERING; BIOSYNTHESIS; CATALYST; CHEMICAL ENGINEERING; CHEMICAL STRUCTURE; CHIRALITY; COMPLEX FORMATION; CONTROLLED STUDY; ENANTIOMER; ENZYME KINETICS; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME SUBSTRATE; HORSE; INDUSTRY; MOLECULAR MODEL; MUTAGENESIS; MUTANT; NONHUMAN; PREDICTION; PRIORITY JOURNAL; STEREOCHEMISTRY; SYNTHESIS; TEMPERATURE; THERMOANAEROBACTER; THERMOANAEROBACTER ETHANOLICUS; THERMOSTABILITY;

ACETONE; ALCOHOL OXIDOREDUCTASES; BENZYL COMPOUNDS; BINDING SITES; CATALYSIS; MOLECULAR STRUCTURE; MUTATION; OXIDATION-REDUCTION; PHENYLETHYL ALCOHOL; STEREOISOMERISM; SUBSTRATE SPECIFICITY; THERMOANAEROBACTER;

EQUIDAE; THERMOANAEROBACTER ETHANOLICUS; THERMOANAEROBACTER ETHANOLICUS ATCC 33223;

EID: 33947138194     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzl052     Document Type: Article

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