Increased nitric oxide production in hepatocytes is involved in liver dysfunction following obstructive jaundice

Journal of Surgical Research

Volumn 106, Issue 1, 2002, Pages 31-36

  Tu, Wei ^a   Kitade, Hiroaki ^a   Satoi, Sohei ^a   Zhang, Zhong Tao ^a   Kaibori, Masaki ^a   Kwon, A Hon ^a   Kamiyama, Yasuo ^a   Okumura, Tadayoshi ^a  

^a KANSAI MEDICAL UNIVERSITY   (Japan)

Author keywords

Adenosine 5 triphosphate; Interleukin 1 ; Ketone body ratio; Nitric oxide; Obstructive jaundice; Primary cultured hepatocytes

Indexed keywords

3 HYDROXYBUTYRIC ACID; ACETOACETIC ACID; ADENOSINE TRIPHOSPHATE; INTERLEUKIN 1BETA; KETONE BODY; N(G) METHYLARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; ENERGY METABOLISM; LIVER CELL; LIVER CELL CULTURE; LIVER DYSFUNCTION; LIVER FUNCTION; LIVER MITOCHONDRION; MALE; NONHUMAN; OBSTRUCTIVE JAUNDICE; OXIDATION REDUCTION STATE; PRIORITY JOURNAL; PROTEIN PROCESSING; RAT; REGULATORY MECHANISM; WESTERN BLOTTING;

EID: 0036374139     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1006/jsre.2002.6436     Document Type: Article

References (40)

1. Factors affecting morbidity and mortality in biliary tract surgery
2. Obstructive jaundice promotes bacterial translocation from the gut
3. The role of bile acids in the development of endotoxemia during obstructive jaundice in the rat
4. Obstructive jaundice alters Kupffer cell function independent of bacterial translocation
5. Cloning, characterization, and expression of a cDNA encoding an inducible nitric oxide synthase from the human chondrocyte
6. Effects of nitric oxide synthase inhibitors on systemic hypotension, cytokines and inducible nitric oxide synthase expression and lung injury following endotoxin administration in rats
7. Trauma increases extrahepatic arginase activity
8. Increased in situ expression of nitric oxide synthase in human colorectal cancer
9. Induction and role of NO synthase in hypotensive hepatic failure
10. Multiple organ failure: Pathophysiology and potential future therapy
11. Hyperdynamic circulation in cirrhosis: A role for nitric oxide?
12. Effect of nitric oxide synthase inhibitors on hypotension in patients with septic shock
13. Lipoic acid prevents development of the hyperdynamic circulation in anesthetized rats with biliary cirrhosis
14. Induction of hepatic Ito cell nitric oxide production after acute endotoxemia
15. Cytokine stimulation of nitric oxide formation and differential regulation in hepatocytes and nonparenchymal cells of endotoxemic rats
16. Regulation of nitric oxide synthesis in the liver
17. Expression of inducible nitric oxide synthase and nitrotyrosine in colonic epithelium in inflammatory bowel disease
18. Role of N-nitroso compounds (NOC) and N-nitrosation in etiology of gastric, esophageal, nasopharyngeal and bladder cancer and contribution to cancer of known exposures to NOC
19. Interleukin-1β markedly stimulates nitric oxide formation in the absence of other cytokines or lipopolysaccharide in primary cultured rat hepatocytes but not in Kupffer cells
20. A central role for interleukin-1β in the in vitro and in vivo regulation of hepatic inducible nitric oxide synthase
21. Evaluation of hepatocyte quality: Cell integrity and metabolic rates
22. Regulation of energy metabolism by interleukin-1β, but not by interleukin-6, is mediated by nitric oxide in primary cultured rat hepatocytes
23. An enhancement of nitric oxide production regulates energy metabolism in rat hepatocytes after a partial hepatectomy
24. Failure of macrophage activation in experimental obstructive jaundice: Association with bacterial translocation
25. 2 in primary cultured rat hepatocytes
26. Quantification of cell nuclei isolated from hepatocytes by cell lysis with nontoxic detergent in citric acid
27. Preparation of isolated rat liver cells
28. 15N]nitrate in biological fluids
29. Adenylate energy charge of rat and human cultured hepatocytes
30. Enzymic determination of D(-)-β-hydroxybutyric acid and acetoacetic acid in blood
31. Tyrosine phosphorylation of inducible nitric oxide synthase: Implications for potential post-translational regulation
32. Role of MAP kinase cascades in inducing arginine transporters and nitric oxide synthase in Raw264 macrophages
33. The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver
34. Nitric oxide: A cytotoxic activated macrophage effector molecule
35. Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells
36. Effects of exogenous and endogenous nitric oxide on mitochondrial respiration of rat hepatocytes
37. The role of nitric oxide in bradycardia of rats with obstructive cholestasis
38. Effects of experimental obstructive jaundice on contractile responses of dog isolated blood vessels: Role of endothelium and duration of bile duct ligation
39. Interaction between prostanoids and nitric oxide in the control of tubular function in rats with chronic bile duct ligation
40. Role of endotoxin and nitric oxide in the pathogenesis of renal failure in obstructive jaundice