Genotype and variations in core promoter and pre-core regions are related to progression of disease in HBV-infected patients from Northern Vietnam

International Journal of Molecular Medicine

Volumn 19, Issue 2, 2007, Pages 293-299

  Truong, Bui Xuan ^a,b   Seo, Yasushi ^a   Yano, Yoshihiko ^a   Ho, Pham Thi Thu ^a   Phuong, Tran Minh ^b   Van Long, Dao ^b   Son, Nguyen Truong ^b   Long, Nguyen Cong ^b   Kato, Hirotaka ^a   Hayashi, Yoshitake ^a   Trach, Nguyen Khanh ^b   Kasuga, Masato ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b BACH MAI HOSPITAL   (Viet Nam)

Author keywords

Core promoter; HBV genotype; Mutations; Northern Vietnam; Pre core

Indexed keywords

ALPHA FETOPROTEIN; HEPATITIS B(E) ANTIGEN; VIRUS DNA;

ADOLESCENT; ADULT; AGED; ARTICLE; BLOOD; CLASSIFICATION; DISEASE COURSE; FEMALE; GENETIC VARIABILITY; GENETICS; GENOTYPE; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; PROMOTER REGION; TREATMENT OUTCOME; VIET NAM;

ADOLESCENT; ADULT; AGED; ALPHA-FETOPROTEINS; DISEASE PROGRESSION; DNA, VIRAL; FEMALE; GENOTYPE; HEPATITIS B; HEPATITIS B E ANTIGENS; HEPATITIS B VIRUS; HUMANS; MALE; MIDDLE AGED; PROMOTER REGIONS (GENETICS); TREATMENT OUTCOME; VARIATION (GENETICS); VIETNAM;

EID: 33847788695     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.19.2.293     Document Type: Article

References (54)

1. Lee WM: Hepatitis B virus infection. N Eng J Med 337: 1733-1743, 1997.
2. Custer B, Sullivan SD, Hazlet TK, Iloeje U and Kowdley K: Global epidemiology of hepatitis B virus. J Clin Gastroenterol 38: S158-S168, 2004.
3. Hipgrave DB, Van NT, Huong VM, et al: Hepatitis B infection in rural Vietnam and the implications for a national program of infant immunization. Am J Tro Med Hyg 69: 288-294, 2003.
4. Okamoto H, Tsuda F, Sukugawa H, et al: Typing hepatitis B virus by homology in nucleotide sequence: comparison of surface antigen subtypes. J Gen Virol 69: 2575-2583, 1988.
5. Norder H, Hammas B, Lofdahl S, Courouce AM and Magnius LO: Comparison of the amino acid sequences of nine different serotypes of hepatitis B surface antigen and genomic classification of the corresponding hepatitis b virus strains. J Gen Virol 73: 1201-1208, 1992.
6. Stuyver L, Gendt SD, Geyt CV, et al: A new genotype of hepatitis B virus: complete genome and phylogenetic relatedness. J Gen Virol 81: 67-74, 2000.
7. Arauz-Ruiz P, Norder H, Robertson BH and Magnius LO: Genotype H: a new Amerindian genotype of hepatitis B virus revealed in central America. J Gen Virol 83: 2059-2073, 2002.
8. Sugauchi F, Orito E, Ichida T, et al: Hepatitis B virus of genotype B with or without recombination with genotype C over pre-core region plus core gene. J Virol 76: 5985-5992, 2002.
9. Sugauchi F, Orito E, Ichida T, et al: Epidemiologic and virologic characteristics of hepatitis B virus genotype B having the recombination with genotype C. Gastroenterology 124: 925-932, 2004.
10. Chan HLY, Tsui SKW, Tse TE, et al: Epidemiological and virological characteristics of 2 subgroups of hepatitis B virus genotype C. J Infect Dis 191: 2022-2032, 2005.
11. Sanchez-Tapias JM, Costa J, Mas A, Bruguera M and Rodes J: Influence of hepatitis B virus genotype on the long-term outcome of chronic hepatitis B in Western patients. Gastroenterology 123: 1848-1856, 2002.
12. Kao JH, Chen PJ, Lai MY and Chen DS: Hepatitis B genotypes correlate with clinical outcomes in patients with chronic hepatitis B. Gastroenterology 118: 554-559, 2000.
13. Sumi H, Yokosuka O, Seki N, et al: Influence of hepatitis virus genotypes on the progression of chronic type B liver disease. Hepatology 37: 19-26, 2003.
14. Chan HLY, Wong ML, Hui AY, Hung LCT, Chan FKL and Sung JJY: Hepatitis B virus genotype C takes more aggressive disease course than hepatitis virus genotype B in hepatitis B e antigen positive patients. J Clin Microbiol 41: 1277-1279, 2003.
15. Chu CJ, Hussain M and Lok ASF: Hepatitis B virus genotype B is associated with earlier HBeAg seroconversion compared with hepatitis B virus genotype C. Gastroenterology 122: 1756-1762, 2002.
16. Carman WF, Hadziyannis S, Mcgarvey MJ, et al: Mutation preventing formation of hepatitis B e antigen in patients with chronic hepatitis b infection. Lancet 9: 588-591, 1989.
17. Lindh M, Andersson AS and Gusdal A: Genotypes, nt1858 variants, and geographic origin of hepatitis B virus large-scale analysis using a new genotyping method. J Infect Dis 175: 1285-1293, 1997.
18. Erhardt A, Reineke U, Blondin D, et al: Mutations of the core promoter and response to interferon treatment in chronic replicative hepatitis B. Hepatology 31: 716-725, 2000.
19. Lindh M, Hannoun C, Dhillon AP, Norkrans G and Horal P: Core promoter mutations and genotypes in relation to viral replication and liver damage in east Asian hepatitis B virus carriers. J Infect Dis 179: 775-782, 1999.
20. Yuen MF, Sablon E, Tanaka Y, et al: Epidemiology study of hepatitis B virus genotypes, core promoter and pre-core mutations of chronic hepatitis B infection in Hong Kong. J Hepatol 41: 119-125, 2004. (Pubitemid 39005162)
21. A mutations in the basic core promoter of hepatitis B virus isolated from Black Africans with hepatocellular carcinoma compared with asymptomatic carriers. Hepatology 29: 946-953, 1999.
22. Orito E, Mizokami M, Sakugawa H, et al: A case-control study for clinical and molecular biological differences between hepatitis B viruses of genotypes B and C. Hepatology 33: 218-223, 2001.
23. Kao JH, Chen PJ, Lai MY and Chen DS: Basal core promoter mutations of hepatitis B virus increase the risk of hepatocellular carcinoma in hepatitis B carriers. Gastroenterology 124: 327-334, 2003.
24. Yuen MF, Tanaka Y, Mizokami M, et al: Role of hepatitis B virus genotypes Ba and C, core promoter and pre-core mutations on hepatocellular carcinoma: a case control study. Carcinogenesis 25: 1593-1598, 2004.
25. Huy TTT, Ushijima H, Win KM, et al: High prevalence of hepatitis B virus pre-S mutant in countries where it is endemic and its relationship with genotype and chronicity. J Clin Microbiol 41: 5449-5455, 2003.
26. Tran HTT, Ushijima H, Quang VX, et al: Prevalence of hepatitis virus types B through E and genotypic distribution of HBV and HCV in Ho Chi Minh city, Vietnam. Hepatol Res 26: 275-280, 2003.
27. Huy TTT, Ushijima H, Quang VX, et al: Characteristics of core promoter and pre-core stop codon mutants of hepatitis B virus in Vietnam. J Med Virol 74: 228-236, 2004.
28. Thuy le TT, Ryo H, Phung LV, Furitsu K and Nomura T: Distribution of genotype/subtype and mutational spectra the surface gene of hepatitis B virus circulating in Hanoi, Vietnam. J Med Virol 76: 161-169, 2005.
29. Hannoun C, Norder H and Lindh M: An aberrant genotype revealed in recombinant hepatitis B virus strains from Vietnam. J Gen Virol 81: 2267-2272, 2000.
30. Ding X, Park YN, Taltavull TS, et al: Geographic characterization of hepatitis virus infection, genotyping of hepatitis B virus, and p53 mutation in hepatocellular carcinoma analyzed by in situ detection of viral genomes from carcinoma tissue: comparison among six different countries. Jpn J Infect Dis 56: 12-18, 2003.
31. Swenson PD, Geyt CV, Alexander ER, et al: Hepatitis B virus genotypes and HBsAg subtypes in refugees and injection drug users in the United States determined by LiPA and monoclonal EIA. J Med Virol 64: 305-311, 2001.
32. Toan NL, Song LH, Kremsner PG, et al: Impact of the hepatitis B virus genotype and genotype mixtures on the course of liver disease in Vietnam. Hepatology 43: 1375-1384, 2006.
33. Song LH, Duy DN, Binh VQ, Luty AJF, Kremsner PG and Bock CT: Low frequency of mutations in the X gene, core promoter and pre-core region of hepatitis B virus infected Vietnamese. J Viral Hepatitis 12: 160-167, 2005.
34. Ding X, Mizokami M, Yao G, et al: Hepatitis B virus genotype distribution among chronic hepatitis B virus carriers in Shanghai, China. Intervirology 44: 43-47, 2001. (Pubitemid 32172943)
35. 1764A) and viral genotype in chronic hepatitis B and hepatocellular carcinoma in Guangxi, China. J Med Virol 68: 33-40, 2002.
36. Lusida MI, Surayah, Sakugawa H, et al: Genotype and subtype analyses of hepatitis B virus (HBV) and possible co-infection of HBV and hepatitis C virus (HCV) of hepatitis D (HDV) in blood donors, patients with chronic liver disease and patients on hemodialysis in Surabaya, Indonesia. Microbiol Immunol 47: 969-975, 2003.
37. Tangkijvanich P, Mahachai V, Komolmit P, Fongsarun J, Theamboonlers A and Poovorawan Y: Hepatitis B virus genotypes and hepatocellular carcinoma in Thailand. World J Gastroenterol 11: 2238-2243, 2005.
38. Fang ZL, Zhuang H, Wang ZY, Ge XM and Harrison TJ: Hepatitis B virus genotypes, phylogeny and occult infection in a region with high incidence of hepatocellular carcinoma in China. World J Gastroenterol 10: 3264-3268, 2004.
39. Mizokami M, Nakano T, Orito E, et al: Hepatitis B virus genotype assignment using fragment length polymorphism pattern. FEBS Lett 450: 66-71, 1999.
40. Usuda S, Okamoto H, Iwanari H, et al: Serological detection of hepatitis B virus genotypes by ELISA with monoclonal antibodies to type-specific epitopes in the preS2-region product. J Virol Method 80: 97-112, 1999.
41. Abe A, Inoue K, Tanaka T, et al: Quantitation of hepatitis B virus genomic DNA by real-time detection PCR. J Clin Microbiol 37: 2899-2903, 1999. (Pubitemid 29391907)
42. Yamaura T, Tanaka E, Matsumoto A, et al: A case-control study for early prediction of hepatitis B e antigen seroconversion by hepatitis B virus DNA levels and mutations in the pre-core region and core promoter. J Med Virol 70: 545-552, 2003.
43. Ljungggren KK, Myhre E and Blackberg J: Clinical and serological variation between patients infected with different hepatitis B virus genotypes. J Clin Microl 42: 5837-5841, 2004.
44. Pujol FH and Devesa M: Genotypic variability of hepatitis viruses associated with chronic infection and the development of hepatocellular carcinoma. J Clin Gastroenterol 39: 611-618, 2005.
45. Hou J, Liu Z and Gu F: Epidemiology and prevention of hepatitis B virus infection. Int J Med Sci 2: 50-57, 2005.
46. Sugauchi F, Kumada H, Sakugawa H, et al: Two subtypes of genotype B (Ba and Bj) of hepatitis B virus in Japan. C Infect Dis 38: 1222-1228, 2004. (Pubitemid 38608562)
47. Norder H, Courouce AM, Coursaget P, et al: Genetic diversity of hepatitis B virus strains derived worldwide: genotypes, subgenotypes, and HBsAg subtypes. Intervirology 47: 289-309, 2004.
48. Chu CM and Liaw YF: Genotype C hepatitis B virus infection is associated with a higher risk of reactivation of hepatitis B and progression to cirrhosis than genotype B: a longitudinal study of hepatitis B e antigen-positive patients with normal aminotransferase levels at baseline. J Hepatol 43: 411-417, 2005.
49. Sugauchi F, Chutaputti A, Orito E, et al: Hepatitis B virus genotypes and clinical manifestation among hepatitis B carriers in Thailand. J Gastroenterol Hepatol 17: 671-676, 2002.
50. Chen CJ, Yang HI, Su J, et al: Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level. JAMA 295: 65-73, 2006.
51. Iloeje UH, Yang HI, Su J, Jen CL, You SL, Chen CJ and the REVEAL-HBV Study Group: Predicting cirrhosis based on the level of circulating hepatitis B viral load. Gastroenterology 130: 678-686, 2006.
52. Truong BX, Seo Y, Kato M, et al: Long-term follow-up Japanese patients with chronic hepatitis B treated with interferon-α. Int J Mol Med 16: 279-284, 2005.
53. Parekh S, Zoulim F, Ahn SH, et al: Genome replication, virion secretion, and e antigen expression of naturally occurring hepatitis B virus core promoter mutants. J Virol 77: 6601-6612, 2003.
54. Tong S, Kim KH, Chante C, Wands J and Li J: Hepatitis B virus e antigen variants. Int J Med Sci 2: 2-7, 2005.