-
1
-
-
27144457667
-
Monoclonal antibody successes in the clinic
-
REICHERT JM, ROSENWEIG CJ, FADEN LD, DEWITZ MC: Monoclonal antibody successes in the clinic. Nat. Biotechnol. (2005) 23(9):1073-1078.
-
(2005)
Nat. Biotechnol
, vol.23
, Issue.9
, pp. 1073-1078
-
-
REICHERT, J.M.1
ROSENWEIG, C.J.2
FADEN, L.D.3
DEWITZ, M.C.4
-
2
-
-
27144532832
-
-
LONBERG N: Human antibodies from transgenic animals. Nat. Biotechnol. (2005) 23(9):1117-1125. • Comprehensive review of drugs in clinical testing, including sequences derived from human immunoglobulin transgenic mice.
-
LONBERG N: Human antibodies from transgenic animals. Nat. Biotechnol. (2005) 23(9):1117-1125. • Comprehensive review of drugs in clinical testing, including sequences derived from human immunoglobulin transgenic mice.
-
-
-
-
3
-
-
0033866627
-
Antibody humanization: A case of the 'Emperor's new clothes'?
-
CLARK M: Antibody humanization: a case of the 'Emperor's new clothes'? Immunol. Today (2006) 21(8):397-402.
-
(2006)
Immunol. Today
, vol.21
, Issue.8
, pp. 397-402
-
-
CLARK, M.1
-
4
-
-
0037235949
-
Engineered antibodies
-
HUDSON PJ, SOURIAU C: Engineered antibodies. Nat. Med. (2003) 9(1):129-134.
-
(2003)
Nat. Med
, vol.9
, Issue.1
, pp. 129-134
-
-
HUDSON, P.J.1
SOURIAU, C.2
-
6
-
-
0033065132
-
Novel super-high affinity sheep monoclonal antibodies against CEA bind colon and lung adenocarcinoma
-
OSBORNE J, HARRISON P, BUTCHER R, EBSWORTH N, TAN K: Novel super-high affinity sheep monoclonal antibodies against CEA bind colon and lung adenocarcinoma. Hybridoma (1999) 18:183-191
-
(1999)
Hybridoma
, vol.18
, pp. 183-191
-
-
OSBORNE, J.1
HARRISON, P.2
BUTCHER, R.3
EBSWORTH, N.4
TAN, K.5
-
7
-
-
0027310612
-
Naturally occurring antibodies devoid of light chains
-
HAMERS-CASTERMAN C, ATARHOUCH T, MUYLDERMANS S et al.: Naturally occurring antibodies devoid of light chains. Nature (1993) (363):446-448.
-
(1993)
Nature
, vol.363
, pp. 446-448
-
-
HAMERS-CASTERMAN, C.1
ATARHOUCH, T.2
MUYLDERMANS, S.3
-
8
-
-
0034161488
-
Camel heavy-chain antibodies: Diverse germline V(H)H and specific mechanisms enlarge the antigen-binding repertoire
-
NGUYEN VK, HAMERS R, WYNS L, MUYLDERMANS S: Camel heavy-chain antibodies: diverse germline V(H)H and specific mechanisms enlarge the antigen-binding repertoire. Eur. Mol. Biol. Org. (2000) 19(5):921-930.
-
(2000)
Eur. Mol. Biol. Org
, vol.19
, Issue.5
, pp. 921-930
-
-
NGUYEN, V.K.1
HAMERS, R.2
WYNS, L.3
MUYLDERMANS, S.4
-
9
-
-
0035251453
-
Bispecific human IgG by design
-
CARTER P: Bispecific human IgG by design. J. Immunol. Methods (2001) 248(1-2):7-15.
-
(2001)
J. Immunol. Methods
, vol.248
, Issue.1-2
, pp. 7-15
-
-
CARTER, P.1
-
10
-
-
0022460927
-
Serum IgG subclasses in normal adults
-
FRENCH MA: Serum IgG subclasses in normal adults. Monogr. Allergy (1986) 19:100.
-
(1986)
Monogr. Allergy
, vol.19
, pp. 100
-
-
FRENCH, M.A.1
-
12
-
-
0020700160
-
Serological aspects of IgG4 Abs: Prolonged immunization results in an IgG4-restricted response
-
AALBERSE R: Serological aspects of IgG4 Abs: Prolonged immunization results in an IgG4-restricted response. J. Immunol. (1983) 130:722.
-
(1983)
J. Immunol
, vol.130
, pp. 722
-
-
AALBERSE, R.1
-
13
-
-
0022503459
-
IgG subclass changes in bacterial infections
-
HAMMARSTROM L, SMITH C: IgG subclass changes in bacterial infections. Monogr. Allergy (1986) 19:122.
-
(1986)
Monogr. Allergy
, vol.19
, pp. 122
-
-
HAMMARSTROM, L.1
SMITH, C.2
-
14
-
-
0022527857
-
IgG subclass in viral infections
-
SKVARIL F: IgG subclass in viral infections. Monogr. Allergy (1986) 19:134.
-
(1986)
Monogr. Allergy
, vol.19
, pp. 134
-
-
SKVARIL, F.1
-
15
-
-
0037033448
-
Antitumor monoclonal antibodies enhance cross-presentation of cellular antigens and the generation of myeloma-specific killer T cells by dendritic cells
-
DHODAPKAR KM, KRASOVSKY J, WILLIAMSON B, DHODAPKAR MV: Antitumor monoclonal antibodies enhance cross-presentation of cellular antigens and the generation of myeloma-specific killer T cells by dendritic cells. J. Exp. Med. (2002) 195(1):125-133.
-
(2002)
J. Exp. Med
, vol.195
, Issue.1
, pp. 125-133
-
-
DHODAPKAR, K.M.1
KRASOVSKY, J.2
WILLIAMSON, B.3
DHODAPKAR, M.V.4
-
16
-
-
0035210219
-
+ lymphocyte responses by dendritic cells armed with PSA/anti-PSA (antigen/antibody) complexes
-
+ lymphocyte responses by dendritic cells armed with PSA/anti-PSA (antigen/antibody) complexes. Clin. Immunol. (2001) 101(3):276-283.
-
(2001)
Clin. Immunol
, vol.101
, Issue.3
, pp. 276-283
-
-
BERLYN, K.A.1
SCHULTES, B.2
LEVEUGLE, B.3
-
17
-
-
0015956495
-
-
JERNE NK: Towards a network theory of the immune system. Ann. Immunol. (Paris) (1974) 125C:373-389. • Seminal work describing the idiotype network theory.
-
JERNE NK: Towards a network theory of the immune system. Ann. Immunol. (Paris) (1974) 125C:373-389. • Seminal work describing the idiotype network theory.
-
-
-
-
18
-
-
3442893072
-
-
SCHULTES B, NICODEMUS C: Using antibodies in tumour immunotherapy. Expert Opin. Biol Ther. (2004) 4(8):1265-1284. • Extensive review of antibodies being studied as immunotherapeutics in cancer.
-
SCHULTES B, NICODEMUS C: Using antibodies in tumour immunotherapy. Expert Opin. Biol Ther. (2004) 4(8):1265-1284. • Extensive review of antibodies being studied as immunotherapeutics in cancer.
-
-
-
-
19
-
-
0037448353
-
Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer
-
ZHANG L, CONEJO-GARCIA JR, KATSAROS D et al.: Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer. N. Engl. J. Med. (2003) 348(3):203-213.
-
(2003)
N. Engl. J. Med
, vol.348
, Issue.3
, pp. 203-213
-
-
ZHANG, L.1
CONEJO-GARCIA, J.R.2
KATSAROS, D.3
-
20
-
-
4644237613
-
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
-
CURIEL TJ, COUKOS G, ZOU L et al.: Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat. Med. (2004) 10(9):942-949.
-
(2004)
Nat. Med
, vol.10
, Issue.9
, pp. 942-949
-
-
CURIEL, T.J.1
COUKOS, G.2
ZOU, L.3
-
21
-
-
0033044588
-
Engineered glycoforms of an antineuroblastoma IgG1 with optimized antibody dependent cellular cytotoxic activity
-
UMANA P, JEAN-MAIRET J, MOUDRY R, AMSTUTZ H, BAILEY J: Engineered glycoforms of an antineuroblastoma IgG1 with optimized antibody dependent cellular cytotoxic activity. Nat. Biotechnol. (1999) 17(2):176- 180.
-
(1999)
Nat. Biotechnol
, vol.17
, Issue.2
, pp. 176-180
-
-
UMANA, P.1
JEAN-MAIRET, J.2
MOUDRY, R.3
AMSTUTZ, H.4
BAILEY, J.5
-
22
-
-
0023911111
-
Reshaping human antibodies for therapy
-
RIECHMANN L, CLARK M, WALDMANN H, WINTER G: Reshaping human antibodies for therapy. Nature (1988) 332(6162):323-327.
-
(1988)
Nature
, vol.332
, Issue.6162
, pp. 323-327
-
-
RIECHMANN, L.1
CLARK, M.2
WALDMANN, H.3
WINTER, G.4
-
23
-
-
15944377427
-
Alemtuzumab in the treatment of chronic lymphocytic leukemia
-
ROBAK T: Alemtuzumab in the treatment of chronic lymphocytic leukemia. BioDrugs (2005) 19(1):9-22.
-
(2005)
BioDrugs
, vol.19
, Issue.1
, pp. 9-22
-
-
ROBAK, T.1
-
24
-
-
0036899229
-
Monoclonal antibodies as therapeutics in oncology
-
TRIKHA M, YAN L, NAKADA MT: Monoclonal antibodies as therapeutics in oncology. Curr. Opin. Biotechnol. (2002) 13(6):609-614.
-
(2002)
Curr. Opin. Biotechnol
, vol.13
, Issue.6
, pp. 609-614
-
-
TRIKHA, M.1
YAN, L.2
NAKADA, M.T.3
-
25
-
-
0028204494
-
New chimeric anti-pancarcinoma monoclonal antibody with superior cytotoxicity-mediating potency
-
VELDERS MP, LITVINOV SV, WARNAAR SO et al.: New chimeric anti-pancarcinoma monoclonal antibody with superior cytotoxicity-mediating potency. Cancer Res. (1994) 54(7):1753-1759.
-
(1994)
Cancer Res
, vol.54
, Issue.7
, pp. 1753-1759
-
-
VELDERS, M.P.1
LITVINOV, S.V.2
WARNAAR, S.O.3
-
26
-
-
0034114769
-
Blockade of receptors for growth factors: An anticancer therapy
-
MENDELSOHN J: Blockade of receptors for growth factors: An anticancer therapy. Clin. Cancer Res. (2000) 6(3):747-753.
-
(2000)
Clin. Cancer Res
, vol.6
, Issue.3
, pp. 747-753
-
-
MENDELSOHN, J.1
-
28
-
-
33644860896
-
The role of gemtuzumab ozogamicin in acute leukaemia therapy
-
TSIMBERIDOU AM, GILES FJ, ESTEY E et al.: The role of gemtuzumab ozogamicin in acute leukaemia therapy. Br. J. Haematol. (2006) 132(4):398-409.
-
(2006)
Br. J. Haematol
, vol.132
, Issue.4
, pp. 398-409
-
-
TSIMBERIDOU, A.M.1
GILES, F.J.2
ESTEY, E.3
-
29
-
-
13244283151
-
Radioimmunotherapy in non-Hodgkin's lymphoma: Focus on 90Y-ibritumomab 305tiuxetan (Zevalin®)
-
WHITE CA: Radioimmunotherapy in non-Hodgkin's lymphoma: Focus on 90Y-ibritumomab 305tiuxetan (Zevalin®). J. Exp. Ther. Oncol. (2004) 4(4):305-316.
-
(2004)
J. Exp. Ther. Oncol
, vol.4
, Issue.4
, pp. 305-316
-
-
WHITE, C.A.1
-
30
-
-
1642267205
-
Yttrium-90-ibritumomab tiuxetan radioimmunotherapy: A new treatment approach for B-cell non-Hodgkin's lymphoma
-
WITZIG T: Yttrium-90-ibritumomab tiuxetan radioimmunotherapy: a new treatment approach for B-cell non-Hodgkin's lymphoma. Drugs Today (Barc.) (2004) 40(2):111-119.
-
(2004)
Drugs Today (Barc.)
, vol.40
, Issue.2
, pp. 111-119
-
-
WITZIG, T.1
-
31
-
-
0028057250
-
Depletion of B cells in vivo by a chimeric mouse human monoclonal antibody to CD20
-
REFF ME, CARNER K, CHAMBERS KS et al.: Depletion of B cells in vivo by a chimeric mouse human monoclonal antibody to CD20. Blood (1994) 83(2):435-445.
-
(1994)
Blood
, vol.83
, Issue.2
, pp. 435-445
-
-
REFF, M.E.1
CARNER, K.2
CHAMBERS, K.S.3
-
32
-
-
0036177103
-
Rituximab: Ongoing and future clinical development
-
GRILLO-LOPEZ AJ, HEDRICK E, RASHFORD M, BENYUNES M: Rituximab: ongoing and future clinical development. Semin. Oncol. (2002) 2981(1):105-112.
-
(2002)
Semin. Oncol
, vol.2981
, Issue.1
, pp. 105-112
-
-
GRILLO-LOPEZ, A.J.1
HEDRICK, E.2
RASHFORD, M.3
BENYUNES, M.4
-
33
-
-
7244248664
-
From the bench to the bedside: Ways to improve rituximab efficacy
-
CARTRON G, WATIER H, GOLAY J, SOLAL-CELIGNY P: From the bench to the bedside: ways to improve rituximab efficacy. Blood (2004) 104(9):2635-2642.
-
(2004)
Blood
, vol.104
, Issue.9
, pp. 2635-2642
-
-
CARTRON, G.1
WATIER, H.2
GOLAY, J.3
SOLAL-CELIGNY, P.4
-
34
-
-
15944417153
-
131I] tositumomab in the management of follicular lymphoma: An oncologist's view
-
131I] tositumomab in the management of follicular lymphoma: an oncologist's view. Q. J. Nucl. Med. Mol. Imaging (2004) 48:305-316.
-
(2004)
Q. J. Nucl. Med. Mol. Imaging
, vol.48
, pp. 305-316
-
-
DAVIES, A.J.1
-
35
-
-
17344368340
-
Divergent roles for Fc receptors and complement in vivo
-
RAVETCH JV, CLYNES RA: Divergent roles for Fc receptors and complement in vivo. Annu. Rev Immunol. (1998) 16(1):421-432.
-
(1998)
Annu. Rev Immunol
, vol.16
, Issue.1
, pp. 421-432
-
-
RAVETCH, J.V.1
CLYNES, R.A.2
-
36
-
-
0026610881
-
Humanization of an anti-p185HER2 antibody for human cancer therapy
-
CARTER P, PRESTA L, GORMAN CM et al.: Humanization of an anti-p185HER2 antibody for human cancer therapy. Proc. Natl Acad. Sci. USA (1992) 89(10):4285-4289.
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, Issue.10
, pp. 4285-4289
-
-
CARTER, P.1
PRESTA, L.2
GORMAN, C.M.3
-
37
-
-
20444502625
-
Trastuzumab: Targeted therapy for the management of HER-2/neu-overexpressing metastatic breast cancer
-
EMENS LA: Trastuzumab: targeted therapy for the management of HER-2/neu-overexpressing metastatic breast cancer. Am. J. Ther. (2005) 12(3):243-253.
-
(2005)
Am. J. Ther
, vol.12
, Issue.3
, pp. 243-253
-
-
EMENS, L.A.1
-
39
-
-
0023525839
-
Ganglioside GD2 specific monoclonal antibody 3F8: A Phase I study in patients with neuroblastoma and malignant melanoma
-
CHEUNG NK, LAZARUS H, MIRALDI FD et al.: Ganglioside GD2 specific monoclonal antibody 3F8: a Phase I study in patients with neuroblastoma and malignant melanoma. J. Clin. Oncol. (1987) 5(9):1430-1440.
-
(1987)
J. Clin. Oncol
, vol.5
, Issue.9
, pp. 1430-1440
-
-
CHEUNG, N.K.1
LAZARUS, H.2
MIRALDI, F.D.3
-
40
-
-
0004712263
-
Regression of cutaneous metastatic melanoma by intralesional injection with human monoclonal antibody to ganglioside GD2
-
IRIE RF, MORTON DL: Regression of cutaneous metastatic melanoma by intralesional injection with human monoclonal antibody to ganglioside GD2. Proc. Natl Acad. Sci. USA (1986) 83(22):8694-8698.
-
(1986)
Proc. Natl Acad. Sci. USA
, vol.83
, Issue.22
, pp. 8694-8698
-
-
IRIE, R.F.1
MORTON, D.L.2
-
42
-
-
0035954624
-
Efficacy of the anti-CD22 recombinant immunotoxin BL22 in chemotherapy-resistant hairy-cell leukemia
-
KREITMAN RJ, WILSON WH, BERGERON K et al.: Efficacy of the anti-CD22 recombinant immunotoxin BL22 in chemotherapy-resistant hairy-cell leukemia. N. Engl. J. Med. (2001) 345(4):241-247.
-
(2001)
N. Engl. J. Med
, vol.345
, Issue.4
, pp. 241-247
-
-
KREITMAN, R.J.1
WILSON, W.H.2
BERGERON, K.3
-
43
-
-
31544455876
-
Antitumor efficacy of a combination of CMC-544 (inotuzumab ozogamicin), a CD22-targeted cytotoxic immunoconjugate of calicheamicin, and rituximab against non-Hodgkin's B-cell lymphoma
-
DIJOSEPH JF, DOUGHER MM, KALYANDRUG LB et al.: Antitumor efficacy of a combination of CMC-544 (inotuzumab ozogamicin), a CD22-targeted cytotoxic immunoconjugate of calicheamicin, and rituximab against non-Hodgkin's B-cell lymphoma. Clin. Cancer Res. (2006) 12(1):242-249.
-
(2006)
Clin. Cancer Res
, vol.12
, Issue.1
, pp. 242-249
-
-
DIJOSEPH, J.F.1
DOUGHER, M.M.2
KALYANDRUG, L.B.3
-
44
-
-
0036941305
-
Monoclonal antibody therapy with CAMPATH-1H in patients with relapsed high- and low-grade non-Hodgkin's lymphomas: A multicenter Phase I/II study
-
UPPENKAMP M, ENGERT A, DIEHL V et al.: Monoclonal antibody therapy with CAMPATH-1H in patients with relapsed high- and low-grade non-Hodgkin's lymphomas: a multicenter Phase I/II study. Ann. Hematol. (2002) 81(1):26-32.
-
(2002)
Ann. Hematol
, vol.81
, Issue.1
, pp. 26-32
-
-
UPPENKAMP, M.1
ENGERT, A.2
DIEHL, V.3
-
45
-
-
0036464719
-
Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor Fcgamma RIIIa gene
-
CARTRON G, DACHEUX L, SALLES G et al.: Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor Fcgamma RIIIa gene. Blood (2002) 99(3):754-758.
-
(2002)
Blood
, vol.99
, Issue.3
, pp. 754-758
-
-
CARTRON, G.1
DACHEUX, L.2
SALLES, G.3
-
46
-
-
33747880652
-
Ex vivo-activated human macrophages kill chronic lymphocytic leukemia cells in the presence of rituximab: Mechanism of antibody-dependent cellular cytotoxicity and impact of human serum
-
LEFEBVRE M-L, KRAUSE SW, SALCEDO M, NARDIN A: Ex vivo-activated human macrophages kill chronic lymphocytic leukemia cells in the presence of rituximab: mechanism of antibody-dependent cellular cytotoxicity and impact of human serum. J. Immunother. (2006) 29(4):388-397.
-
(2006)
J. Immunother
, vol.29
, Issue.4
, pp. 388-397
-
-
LEFEBVRE, M.-L.1
KRAUSE, S.W.2
SALCEDO, M.3
NARDIN, A.4
-
47
-
-
28544440831
-
Complement-mediated mechanisms in anti-GD2 monoclonal antibody therapy of murine metastatic cancer
-
IMAI M, LANDEN C, OHTA R, CHEUNG NK, TOMLINSON S: Complement-mediated mechanisms in anti-GD2 monoclonal antibody therapy of murine metastatic cancer. Cancer Res. (2005) 65(22):10562-10568.
-
(2005)
Cancer Res
, vol.65
, Issue.22
, pp. 10562-10568
-
-
IMAI, M.1
LANDEN, C.2
OHTA, R.3
CHEUNG, N.K.4
TOMLINSON, S.5
-
48
-
-
17844409102
-
Antibodies against tumor cell glycolipids and proteins, but not mucins, mediate complement-dependent cytotoxicity
-
RAGUPATHI G, LIU NX, MUSSELLI C et al.: Antibodies against tumor cell glycolipids and proteins, but not mucins, mediate complement-dependent cytotoxicity. J. Immunol. (2005) 174(9):5706-5712.
-
(2005)
J. Immunol
, vol.174
, Issue.9
, pp. 5706-5712
-
-
RAGUPATHI, G.1
LIU, N.X.2
MUSSELLI, C.3
-
49
-
-
0035675556
-
Anti-ErbB-2 monoclonal antibodies and ErbB-2 directed vaccines
-
YIP Y, WARD R: Anti-ErbB-2 monoclonal antibodies and ErbB-2 directed vaccines. Cancer Immunol. Immunother. (2002) 50(11):569-587.
-
(2002)
Cancer Immunol. Immunother
, vol.50
, Issue.11
, pp. 569-587
-
-
YIP, Y.1
WARD, R.2
-
50
-
-
2142641698
-
-
SALTZ LB, MEROPOL NJ, LOEHRER PJ SR et al.: Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor. J. Clin. Oncol. (2004) 22(7):1201-1208.
-
SALTZ LB, MEROPOL NJ, LOEHRER PJ SR et al.: Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor. J. Clin. Oncol. (2004) 22(7):1201-1208.
-
-
-
-
51
-
-
0035180065
-
-
SAKAGUCHI S, SAKAGUCHI N, SHIMIZU J et al.: Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol. Rev. (2001) 182(1):18-32. • Description of T regulatory cells.
-
SAKAGUCHI S, SAKAGUCHI N, SHIMIZU J et al.: Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol. Rev. (2001) 182(1):18-32. • Description of T regulatory cells.
-
-
-
-
52
-
-
0033485743
-
Identification of an IL-10-producing HLA-DR-negative monocyte subset in the malignant ascites of patients with ovarian carcinoma that inhibits cytokine protein expression and proliferation of autologous T cells
-
LOERCHER AE, NASH MA, KAVANAGH JJ, PLATSOUCAS CD, FREEDMAN RS: Identification of an IL-10-producing HLA-DR-negative monocyte subset in the malignant ascites of patients with ovarian carcinoma that inhibits cytokine protein expression and proliferation of autologous T cells. J. Immunol. (1999) 163(11):6251-6260.
-
(1999)
J. Immunol
, vol.163
, Issue.11
, pp. 6251-6260
-
-
LOERCHER, A.E.1
NASH, M.A.2
KAVANAGH, J.J.3
PLATSOUCAS, C.D.4
FREEDMAN, R.S.5
-
53
-
-
33645853780
-
B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma
-
KRYCZEK I, ZOU L, RODRIGUEZ P et al.: B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma. J. Exp. Med. (2006) 203(4):871-881.
-
(2006)
J. Exp. Med
, vol.203
, Issue.4
, pp. 871-881
-
-
KRYCZEK, I.1
ZOU, L.2
RODRIGUEZ, P.3
-
54
-
-
33749427617
-
Myeloid suppressor cells regulate the adaptive immune response to cancer
-
FREY AB: Myeloid suppressor cells regulate the adaptive immune response to cancer. J. Clin. Invest. (2006) 116(10):2587-2590.
-
(2006)
J. Clin. Invest
, vol.116
, Issue.10
, pp. 2587-2590
-
-
FREY, A.B.1
-
55
-
-
33749425534
-
Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells
-
GALLINA G, DOLCETTI L, SERAFINI P et al.: Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells. J. Clin. Invest. (2006) 116(10):2777-2790.
-
(2006)
J. Clin. Invest
, vol.116
, Issue.10
, pp. 2777-2790
-
-
GALLINA, G.1
DOLCETTI, L.2
SERAFINI, P.3
-
56
-
-
0038153907
-
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
-
PHAN GQ, YANG JC, SHERRY RM et al.: Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma. Proc. Natl Acad. Sci. USA (2003) 100(14):8372-8377.
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, Issue.14
, pp. 8372-8377
-
-
PHAN, G.Q.1
YANG, J.C.2
SHERRY, R.M.3
-
57
-
-
0033517152
-
Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation
-
VAN ELSAS A, HURWITZ AA, ALLISON JP: Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation. J. Exp. Med. (1999) 190(3):355-366.
-
(1999)
J. Exp. Med
, vol.190
, Issue.3
, pp. 355-366
-
-
VAN ELSAS, A.1
HURWITZ, A.A.2
ALLISON, J.P.3
-
58
-
-
33646886997
-
Biologic and immunomodulatory events after CTLA-4 blockade with ticilimumab in patients with advanced malignant melanoma
-
REUBEN J, LEE B, LI C et al.: Biologic and immunomodulatory events after CTLA-4 blockade with ticilimumab in patients with advanced malignant melanoma. Cancer (2006) 106(11):2437-2444.
-
(2006)
Cancer
, vol.106
, Issue.11
, pp. 2437-2444
-
-
REUBEN, J.1
LEE, B.2
LI, C.3
-
59
-
-
28244492012
-
Analysis of the cellular mechanism of antitumor responses and autoimmunity in patients treated with CTLA-4 blockade
-
MAKER A, ATTIA P, ROSENBERG SA: Analysis of the cellular mechanism of antitumor responses and autoimmunity in patients treated with CTLA-4 blockade. J. Immunol. (2005) 175(11):7746-7754.
-
(2005)
J. Immunol
, vol.175
, Issue.11
, pp. 7746-7754
-
-
MAKER, A.1
ATTIA, P.2
ROSENBERG, S.A.3
-
60
-
-
0344341626
-
Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
-
HODI FS, MIHM MC, SOIFFER RJ et al.: Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients. Proc. Natl Acad. Sci. USA (2003) 100(8):4712-4717.
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, Issue.8
, pp. 4712-4717
-
-
HODI, F.S.1
MIHM, M.C.2
SOIFFER, R.J.3
-
61
-
-
33646794392
-
-
KORMAN A, PEGGS K, ALLISON J: Checkpoint blockade in cancer immunotherapy. Adv. Immunol. (2006) 90:297-339. • Excellent review of counter-regulation in cancer immunotherapy.
-
KORMAN A, PEGGS K, ALLISON J: Checkpoint blockade in cancer immunotherapy. Adv. Immunol. (2006) 90:297-339. • Excellent review of counter-regulation in cancer immunotherapy.
-
-
-
-
62
-
-
33644659256
-
-
PEGGS KS, QUEZADA SA, KORMAN AJ, ALLISON JP: Principles and use of anti-CTLA4 antibody in human cancer immunotherapy. Curr. Opin. Immunol. (2006) 18(2):206-213. • Comprehensive and up-to-date review of anti-CTLA-4 and its use in cancer therapy.
-
PEGGS KS, QUEZADA SA, KORMAN AJ, ALLISON JP: Principles and use of anti-CTLA4 antibody in human cancer immunotherapy. Curr. Opin. Immunol. (2006) 18(2):206-213. • Comprehensive and up-to-date review of anti-CTLA-4 and its use in cancer therapy.
-
-
-
-
63
-
-
33746924449
-
Combination therapy with anti-CTL antigen-4 and anti-4-1BB antibodies enhances cancer immunity and reduces autoimmunity
-
KOCAK E, LUTE K, CHANG X et al.: Combination therapy with anti-CTL antigen-4 and anti-4-1BB antibodies enhances cancer immunity and reduces autoimmunity. Cancer Res. (2006) 66(14):7276-7284.
-
(2006)
Cancer Res
, vol.66
, Issue.14
, pp. 7276-7284
-
-
KOCAK, E.1
LUTE, K.2
CHANG, X.3
-
64
-
-
23844542702
-
Cutting Edge: Proangiogenic properties of alternatively activated dendritic cells
-
RIBOLDI E, MUSSO T, MORONI E et al.: Cutting Edge: Proangiogenic properties of alternatively activated dendritic cells. J. Immunol. (2005) 175(5):2788-2792.
-
(2005)
J. Immunol
, vol.175
, Issue.5
, pp. 2788-2792
-
-
RIBOLDI, E.1
MUSSO, T.2
MORONI, E.3
-
65
-
-
0032741283
-
Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function
-
GABRILOVICH DI, ISHIDA T, NADAF S, OHM JE, CARBONE DP: Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function. Clin. Cancer Res. (1999) 5(10):2963-2970.
-
(1999)
Clin. Cancer Res
, vol.5
, Issue.10
, pp. 2963-2970
-
-
GABRILOVICH, D.I.1
ISHIDA, T.2
NADAF, S.3
OHM, J.E.4
CARBONE, D.P.5
-
66
-
-
22144483117
-
Vascular endothelial growth factor impairs the functional ability of dendritic cells through ID pathways
-
LAXMANAN S, ROBERTSON S, WANG E et al.: Vascular endothelial growth factor impairs the functional ability of dendritic cells through ID pathways. Biochem. Biophys. Res. Commun. (2005) 334(1):193-198.
-
(2005)
Biochem. Biophys. Res. Commun
, vol.334
, Issue.1
, pp. 193-198
-
-
LAXMANAN, S.1
ROBERTSON, S.2
WANG, E.3
-
67
-
-
4143123338
-
Epratuzumab, a humanized anti-CD22 antibody, in aggressive non-Hodgkin's lymphoma
-
LEONARD JP, COLEMAN M, KETAS JC et al.: Epratuzumab, a humanized anti-CD22 antibody, in aggressive non-Hodgkin's lymphoma. Clin. Cancer Res. (2004) 10:5327-5334.
-
(2004)
Clin. Cancer Res
, vol.10
, pp. 5327-5334
-
-
LEONARD, J.P.1
COLEMAN, M.2
KETAS, J.C.3
-
68
-
-
22344436992
-
Phase I/II study of galiximab, an anti-CD80 antibody, for relapsed or refractory follicular lymphoma
-
CZUCZMAN MS, THALL AD, WITZIG TE et al.: Phase I/II study of galiximab, an anti-CD80 antibody, for relapsed or refractory follicular lymphoma. J. Clin. Oncol. (2005) 23(19):4390-4398.
-
(2005)
J. Clin. Oncol
, vol.23
, Issue.19
, pp. 4390-4398
-
-
CZUCZMAN, M.S.1
THALL, A.D.2
WITZIG, T.E.3
-
69
-
-
33646876477
-
Glucocorticoid-induced TNF receptor family related gene activation overcomes tolerance/ignorance to melanoma differentiation antigens and enhances antitumor immunity
-
RAMIREZ-MONTAGUT T, CHOW A, HIRSCHHORN-CYMERMAN D et al.: Glucocorticoid-induced TNF receptor family related gene activation overcomes tolerance/ignorance to melanoma differentiation antigens and enhances antitumor immunity. J. Immunol. (2006) 176(11):6434-6442.
-
(2006)
J. Immunol
, vol.176
, Issue.11
, pp. 6434-6442
-
-
RAMIREZ-MONTAGUT, T.1
CHOW, A.2
HIRSCHHORN-CYMERMAN, D.3
-
70
-
-
33748416499
-
Cytokine storm in a Phase I trial of the anti-CD28 monoclonal antibody TGN1412
-
SUNTHARALINGAM G, PERRY MR, WARD S et al.: Cytokine storm in a Phase I trial of the anti-CD28 monoclonal antibody TGN1412. N. Engl. J. Med. (2006) 355(10):1018-1028.
-
(2006)
N. Engl. J. Med
, vol.355
, Issue.10
, pp. 1018-1028
-
-
SUNTHARALINGAM, G.1
PERRY, M.R.2
WARD, S.3
-
71
-
-
33744809307
-
Is tumor immunity the same thing as autoimmunity? Implications for cancer immunotherapy
-
KAUFMAN HL, WOLCHOK JD: Is tumor immunity the same thing as autoimmunity? Implications for cancer immunotherapy. J. Clin. Oncol. (2006) 24(15):2230-2232.
-
(2006)
J. Clin. Oncol
, vol.24
, Issue.15
, pp. 2230-2232
-
-
KAUFMAN, H.L.1
WOLCHOK, J.D.2
-
72
-
-
33646419260
-
Agonist anti-GITR antibody enhances vaccine-induced CD8+ T-cell responses and tumor immunity
-
COHEN AD, DIAB A, PERALES MA et al.: Agonist anti-GITR antibody enhances vaccine-induced CD8+ T-cell responses and tumor immunity. Cancer Res. (2006) 66(9):4904-4912.
-
(2006)
Cancer Res
, vol.66
, Issue.9
, pp. 4904-4912
-
-
COHEN, A.D.1
DIAB, A.2
PERALES, M.A.3
-
73
-
-
5144228905
-
In vivo elimination of CD25+ regulatory T cells leads to tumor rejection of B16F10 melanoma, when combined with interleukin-12 gene transfer
-
NAGAI H, HORIKAWA T, HARA I et al.: In vivo elimination of CD25+ regulatory T cells leads to tumor rejection of B16F10 melanoma, when combined with interleukin-12 gene transfer. Exp. Dermatol. (2004) 13(10):613-620.
-
(2004)
Exp. Dermatol
, vol.13
, Issue.10
, pp. 613-620
-
-
NAGAI, H.1
HORIKAWA, T.2
HARA, I.3
-
74
-
-
33845885624
-
Systemic anti-CD25 monoclonal antibody administration safely enhances immunity in murine glioma without eliminating regulatory T cells
-
FECCI PE, SWEENEY AE, GROSSI PM et al.: Systemic anti-CD25 monoclonal antibody administration safely enhances immunity in murine glioma without eliminating regulatory T cells. Clin. Cancer Res. (2006) 12(14):4294-4305.
-
(2006)
Clin. Cancer Res
, vol.12
, Issue.14
, pp. 4294-4305
-
-
FECCI, P.E.1
SWEENEY, A.E.2
GROSSI, P.M.3
-
75
-
-
33645906878
-
Intra-tumoural regulatory T cells: A potential new target in cancer immunotherapy
-
NEEDHAM D, LEE J, BEILHARZ M: Intra-tumoural regulatory T cells: a potential new target in cancer immunotherapy. Biochem. Biophys. Res. Commun. (2006) 343(3):684-691.
-
(2006)
Biochem. Biophys. Res. Commun
, vol.343
, Issue.3
, pp. 684-691
-
-
NEEDHAM, D.1
LEE, J.2
BEILHARZ, M.3
-
76
-
-
25844517914
-
Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells
-
KO K, YAMAZAKI S, NAKAMURA K et al.: Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells. J. Exp. Med. (2005) 202(7):885-891.
-
(2005)
J. Exp. Med
, vol.202
, Issue.7
, pp. 885-891
-
-
KO, K.1
YAMAZAKI, S.2
NAKAMURA, K.3
-
77
-
-
20444485236
-
Plasmacytoid dendritic cells induce CD8+ regulatory T cells in human ovarian carcinoma
-
WEI S, KRYCZEK I, ZOU L et al.: Plasmacytoid dendritic cells induce CD8+ regulatory T cells in human ovarian carcinoma. Cancer Res. (2005) 65(12):5020-5026.
-
(2005)
Cancer Res
, vol.65
, Issue.12
, pp. 5020-5026
-
-
WEI, S.1
KRYCZEK, I.2
ZOU, L.3
-
78
-
-
0035658072
-
Stromal-derived factor-1 in human tumors recruits and alters the function of plasmacytoid precursor dendritic cells
-
ZOU W, MACHELON V, CURIEL TJ et al.: Stromal-derived factor-1 in human tumors recruits and alters the function of plasmacytoid precursor dendritic cells. Nat. Med. (2001) 7(12):1339-1346.
-
(2001)
Nat. Med
, vol.7
, Issue.12
, pp. 1339-1346
-
-
ZOU, W.1
MACHELON, V.2
CURIEL, T.J.3
-
79
-
-
28544433483
-
The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer
-
WOLF D, WOLF AM, RUMPOLD H et al.: The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer. Clin. Cancer Res. (2005) 11(23):8326-8331.
-
(2005)
Clin. Cancer Res
, vol.11
, Issue.23
, pp. 8326-8331
-
-
WOLF, D.1
WOLF, A.M.2
RUMPOLD, H.3
-
80
-
-
33644586895
-
Cytokine expression profile in human pancreatic carcinoma cells and in surgical specimans: Implications for survival
-
BELLONE G, SMIRNE C, MAURI F et al.: Cytokine expression profile in human pancreatic carcinoma cells and in surgical specimans: Implications for survival. Cancer Immunol. Immunother. (2006) 55(6):684-698.
-
(2006)
Cancer Immunol. Immunother
, vol.55
, Issue.6
, pp. 684-698
-
-
BELLONE, G.1
SMIRNE, C.2
MAURI, F.3
-
81
-
-
19944393861
-
Phase I trial of a murine antibody to MUC1 in patients with metastatic cancer: Evidence for the activation of humoral and cellular antitumor immunity
-
DE BONO JS, RHA SY, STEPHENSON J et al.: Phase I trial of a murine antibody to MUC1 in patients with metastatic cancer: evidence for the activation of humoral and cellular antitumor immunity. Ann. Oncol. (2004) 15:1825-1833.
-
(2004)
Ann. Oncol
, vol.15
, pp. 1825-1833
-
-
DE BONO, J.S.1
RHA, S.Y.2
STEPHENSON, J.3
-
82
-
-
3142670929
-
CA125- and tumor specific T-cell responses correlate with prolonged survival in oregovomab-treated recurrent ovarian cancer patients
-
GORDON AN, SCHULTES BC, GALLION H et al.: CA125- and tumor specific T-cell responses correlate with prolonged survival in oregovomab-treated recurrent ovarian cancer patients. Gynecol. Oncol. (2004) 94:340-351.
-
(2004)
Gynecol. Oncol
, vol.94
, pp. 340-351
-
-
GORDON, A.N.1
SCHULTES, B.C.2
GALLION, H.3
-
83
-
-
4444383336
-
-
BEREK JS, TAYLOR PT, GORDON A et al.: Randomized, placebo-controlled study of oregovomab for consolidation of clinical remission in patients with advanced ovarian cancer. J. Clin. Oncol. (2004) 22(17):3507-3516. • Results of Phase II/III trial with oregovomab in advanced ovarian cancer.
-
BEREK JS, TAYLOR PT, GORDON A et al.: Randomized, placebo-controlled study of oregovomab for consolidation of clinical remission in patients with advanced ovarian cancer. J. Clin. Oncol. (2004) 22(17):3507-3516. • Results of Phase II/III trial with oregovomab in advanced ovarian cancer.
-
-
-
-
84
-
-
33746888249
-
Anti-inflammatory activity of immunoglobulin G resulting from Fc sialylation
-
KANEKO Y, NIMMERJAHN F, RAVETCH JV: Anti-inflammatory activity of immunoglobulin G resulting from Fc sialylation. Science (2006) 313(5787):670-673.
-
(2006)
Science
, vol.313
, Issue.5787
, pp. 670-673
-
-
KANEKO, Y.1
NIMMERJAHN, F.2
RAVETCH, J.V.3
-
85
-
-
33847717524
-
-
LINDEMAN J: Speculations on idiotypes of homebodies. Ann. Immunol. (Paris) (1973) 124:171-184. • Seminal work on the idiotype network.
-
LINDEMAN J: Speculations on idiotypes of homebodies. Ann. Immunol. (Paris) (1973) 124:171-184. • Seminal work on the idiotype network.
-
-
-
-
86
-
-
12144287745
-
Vaccination of patients with advanced ovarian carcinoma with the anti-idiotype ACA125: Immunological response and survival (Phase Ib/II)
-
REINARTZ S, KÖHLER S, SCHLEBUSCH H et al.: Vaccination of patients with advanced ovarian carcinoma with the anti-idiotype ACA125: immunological response and survival (Phase Ib/II). Clin. Cancer Res. (2004) 10:1580-1587.
-
(2004)
Clin. Cancer Res
, vol.10
, pp. 1580-1587
-
-
REINARTZ, S.1
KÖHLER, S.2
SCHLEBUSCH, H.3
-
87
-
-
21044444425
-
Immune responses to the 105AD7 human anti-idiotypic vaccine after intensive chemotherapy, for osteosarcoma
-
PRITCHARD-JONES K, SPENDLOVE I, WILTON C et al.: Immune responses to the 105AD7 human anti-idiotypic vaccine after intensive chemotherapy, for osteosarcoma. Br. J. Cancer (2005) 92(8):1358-1365.
-
(2005)
Br. J. Cancer
, vol.92
, Issue.8
, pp. 1358-1365
-
-
PRITCHARD-JONES, K.1
SPENDLOVE, I.2
WILTON, C.3
-
88
-
-
0041569142
-
Use of the anti-idiotype breast cancer vaccine 11D10 in conjunction with autologous stem cell transplantation in patients with metastic breast cancer
-
REECE D, FOON KA, BHATTACHARYA-CHATTERJEE M et al.: Use of the anti-idiotype breast cancer vaccine 11D10 in conjunction with autologous stem cell transplantation in patients with metastic breast cancer. Clin. Breast Cancer (2003) 3(4):152-157.
-
(2003)
Clin. Breast Cancer
, vol.3
, Issue.4
, pp. 152-157
-
-
REECE, D.1
FOON, K.A.2
BHATTACHARYA-CHATTERJEE, M.3
-
89
-
-
0038577172
-
Immune responses in breast cancer patients immunized with an anti-idiotype antibody mimicking NeuGc-containing gangliosides
-
DÍAZ A, ALFONSO M, ALONSO R et al.: Immune responses in breast cancer patients immunized with an anti-idiotype antibody mimicking NeuGc-containing gangliosides. Clin. Immunol. (2003) 107(2):80-89.
-
(2003)
Clin. Immunol
, vol.107
, Issue.2
, pp. 80-89
-
-
DÍAZ, A.1
ALFONSO, M.2
ALONSO, R.3
-
90
-
-
33749316413
-
Phase I study of abagovomab in patients with epithelial ovarian, fallopian tube, or primary peritoneal cancer
-
SABBATINI P, DUPONT J, AGHAJANIAN C et al.: Phase I study of abagovomab in patients with epithelial ovarian, fallopian tube, or primary peritoneal cancer. Clin. Cancer Res. (2006) 12(18):5503-5510.
-
(2006)
Clin. Cancer Res
, vol.12
, Issue.18
, pp. 5503-5510
-
-
SABBATINI, P.1
DUPONT, J.2
AGHAJANIAN, C.3
-
91
-
-
27244446896
-
-
GIACCONE G, DEBRUYNE C, FELIP E et al.: Phase III study of adjuvant vaccination with Bec2/bacille Calmette-Guerin in responding patients with limited-disease small-cell lung cancer. J. Clin. Oncol. (2005) 23(28):6854-6864. • Description of the Phase III study results with the BEC2 anti-idiotypic antibody.
-
GIACCONE G, DEBRUYNE C, FELIP E et al.: Phase III study of adjuvant vaccination with Bec2/bacille Calmette-Guerin in responding patients with limited-disease small-cell lung cancer. J. Clin. Oncol. (2005) 23(28):6854-6864. • Description of the Phase III study results with the BEC2 anti-idiotypic antibody.
-
-
-
-
92
-
-
3442902815
-
Fine specificity of high molecular weight-melanoma-associated antigen-specific cytotoxic T lymphocytes elicited by anti-idiotypic monoclonal antibodies in patiens with melanoma
-
MURRAY JL, GILLOGLY M, KAWANO K et al.: Fine specificity of high molecular weight-melanoma-associated antigen-specific cytotoxic T lymphocytes elicited by anti-idiotypic monoclonal antibodies in patiens with melanoma. Cancer Res. (2004) 64(15):5481-5488.
-
(2004)
Cancer Res
, vol.64
, Issue.15
, pp. 5481-5488
-
-
MURRAY, J.L.1
GILLOGLY, M.2
KAWANO, K.3
|