Loss of Glutamatergic Pyramidal Neurons in Frontal and Temporal Cortex Resulting from Attenuation of FGFR1 Signaling Is Associated with Spontaneous Hyperactivity in Mice

Journal of Neuroscience

Volumn 24, Issue 9, 2004, Pages 2247-2258

  Shin, Dana M ^a   Korada, Sailaja ^a,e   Raballo, Rossana ^a   Shashikant, Cooduvalli S ^b,e   Simeone, Antonio ^d   Taylor, Jane R ^c   Vaccarino, Flora ^a,c  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d KING'S COLLEGE LONDON   (United Kingdom)

^e PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

Cerebral cortex; FGFR; Fibroblast growth factor; Hyperactivity; Proliferation; Pyramidal neuron; Radial glia; Tbr1

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; AMPHETAMINE; GLUTAMATE RECEPTOR; GUANFACINE; PROTEIN TYROSINE KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BASAL GANGLION; BRAIN DEVELOPMENT; CELL PROLIFERATION; COILED BODY; CONTROLLED STUDY; DENDRITE; DISEASE ASSOCIATION; EMBRYO; EMBRYO DEVELOPMENT; FRONTAL CORTEX; GABAERGIC SYSTEM; GENE CONSTRUCT; GLIA; HYPERACTIVITY; INTERNEURON; LOCOMOTION; MONOAMINERGIC SYSTEM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; REGULATORY MECHANISM; TEMPORAL CORTEX; TRANSGENE; TRANSGENIC MOUSE;

ADRENERGIC ALPHA-AGONISTS; AMPHETAMINE; ANIMALS; CELL DIFFERENTIATION; CELL DIVISION; FRONTAL LOBE; GLUTAMIC ACID; GUANFACINE; HUMANS; HYPERKINESIS; MICE; MICE, TRANSGENIC; NERVOUS SYSTEM MALFORMATIONS; NEURAL INHIBITION; PYRAMIDAL CELLS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 1; RECEPTORS, ADRENERGIC, ALPHA-2; RECEPTORS, FIBROBLAST GROWTH FACTOR; SIGNAL TRANSDUCTION; STEREOTYPIC MOVEMENT DISORDER; TEMPORAL LOBE;

EID: 1542317054     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5285-03.2004     Document Type: Article

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