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Volumn 66, Issue 16, 2006, Pages 2109-2119

Rimonabant

Author keywords

[No Author keywords available]

Indexed keywords

DIGOXIN; KETOCONAZOLE; MIDAZOLAM; NICOTINE; ORAL CONTRACEPTIVE AGENT; PLACEBO; RIMONABANT; TETRAHYDROLIPSTATIN; WARFARIN; ANTIOBESITY AGENT; CANNABINOID 1 RECEPTOR; PIPERIDINE DERIVATIVE; PYRAZOLE DERIVATIVE;

EID: 33847703790     PISSN: 00126667     EISSN: 00126667     Source Type: Journal    
DOI: 10.2165/00003495-200666160-00006     Document Type: Article
Times cited : (57)

References (44)
  • 1
    • 33847728681 scopus 로고    scopus 로고
    • World Health Organization, online, Available from URL:, Accessed Jul
    • World Health Organization. Obesity and overweight. 2006 [online]. Available from URL: http://www.who.int/ [Accessed 2006 Jul]
    • (2006) Obesity and overweight. 2006
  • 3
    • 33645468559 scopus 로고    scopus 로고
    • Safety of drug therapies used for weight loss and treatment of obesity
    • Ioannides-Demos LL, Proietto J, Tonkin AM, et al. Safety of drug therapies used for weight loss and treatment of obesity. Drug Saf 2006; 29 (4): 277-302
    • (2006) Drug Saf , vol.29 , Issue.4 , pp. 277-302
    • Ioannides-Demos, L.L.1    Proietto, J.2    Tonkin, A.M.3
  • 4
    • 0242268553 scopus 로고    scopus 로고
    • The molecular logic of endocannabinoid signalling
    • Nov;
    • Piomelli D. The molecular logic of endocannabinoid signalling. Nat Rev Neurosci 2003 Nov; 4 (11): 873-84
    • (2003) Nat Rev Neurosci , vol.4 , Issue.11 , pp. 873-884
    • Piomelli, D.1
  • 5
    • 15444362306 scopus 로고    scopus 로고
    • Rimonabant: A selective CB1 antagonist
    • Apr;
    • Boyd ST, Fremming BA. Rimonabant: a selective CB1 antagonist. Ann Pharmacother 2005 Apr; 39 (4): 684-90
    • (2005) Ann Pharmacother , vol.39 , Issue.4 , pp. 684-690
    • Boyd, S.T.1    Fremming, B.A.2
  • 6
    • 32444440208 scopus 로고    scopus 로고
    • The emerging role of the endocannabinoid system in endocrine regulation and energy balance
    • Feb;
    • Pagotto U, Marsicano G, Cota D, et al. The emerging role of the endocannabinoid system in endocrine regulation and energy balance. Endocr Rev 2006 Feb; 27 (1): 73-100
    • (2006) Endocr Rev , vol.27 , Issue.1 , pp. 73-100
    • Pagotto, U.1    Marsicano, G.2    Cota, D.3
  • 7
    • 25844460609 scopus 로고    scopus 로고
    • Activation of the peripheral endocannabinoid system in human obesity
    • Engeli S, Bohnke J, Feldpausch M, et al. Activation of the peripheral endocannabinoid system in human obesity. Diabetes 2005; 54: 2838-43
    • (2005) Diabetes , vol.54 , pp. 2838-2843
    • Engeli, S.1    Bohnke, J.2    Feldpausch, M.3
  • 8
    • 0037374766 scopus 로고    scopus 로고
    • The cannabinoid CB1 receptor antagonist SR141716 increases Acrp30 mRNA expression in adipose tissue of obese fa/fa rats and in cultured adipocyte cells
    • Apr;
    • Bensaid M, Gary-Bobo M, Esclangon A, et al. The cannabinoid CB1 receptor antagonist SR141716 increases Acrp30 mRNA expression in adipose tissue of obese fa/fa rats and in cultured adipocyte cells. Mol Pharmacol 2003 Apr; 63 (4): 908-14
    • (2003) Mol Pharmacol , vol.63 , Issue.4 , pp. 908-914
    • Bensaid, M.1    Gary-Bobo, M.2    Esclangon, A.3
  • 9
    • 20944436157 scopus 로고    scopus 로고
    • Endocannabi-noid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-indiced obesity
    • Osei-Hyiaman D, DePetrillo M, Pacher P, et al. Endocannabi-noid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-indiced obesity. J Clin Invest 2005; 115 (5): 1298-305
    • (2005) J Clin Invest , vol.115 , Issue.5 , pp. 1298-1305
    • Osei-Hyiaman, D.1    DePetrillo, M.2    Pacher, P.3
  • 10
    • 13244249625 scopus 로고    scopus 로고
    • Effects of the cannabinoid CB1 receptor antagonist SR141716 on oxygen consumption and soleus muscle glucose uptake in Lep(ob)/Lep(ob) mice
    • Feb;
    • Liu YL, Connoley IP, Wilson CA, et al. Effects of the cannabinoid CB1 receptor antagonist SR141716 on oxygen consumption and soleus muscle glucose uptake in Lep(ob)/Lep(ob) mice. Int J Obes Relat Metab Disord 2005 Feb; 29 (2): 183-7
    • (2005) Int J Obes Relat Metab Disord , vol.29 , Issue.2 , pp. 183-187
    • Liu, Y.L.1    Connoley, I.P.2    Wilson, C.A.3
  • 11
    • 33747644061 scopus 로고    scopus 로고
    • Regulation, function and dysregulation of endocannabinoids in models of adipose and beta-pancreatic cells and in obesity and hyperglycaemia
    • Matias I, Gontheir M-P, Orlando P, et al. Regulation, function and dysregulation of endocannabinoids in models of adipose and beta-pancreatic cells and in obesity and hyperglycaemia. J Clin Endocrin Metab 2006; 91 (8): 3171-80
    • (2006) J Clin Endocrin Metab , vol.91 , Issue.8 , pp. 3171-3180
    • Matias, I.1    Gontheir, M.-P.2    Orlando, P.3
  • 12
    • 17844388556 scopus 로고    scopus 로고
    • Endocannabinoid control of food intake and energy balance
    • May;
    • Di Marzo V, Matias I. Endocannabinoid control of food intake and energy balance. Nat Neurosci 2005 May; 8 (5): 585-9
    • (2005) Nat Neurosci , vol.8 , Issue.5 , pp. 585-589
    • Di Marzo, V.1    Matias, I.2
  • 13
    • 33845522074 scopus 로고    scopus 로고
    • Dysregulation of the peripheral and adipose tissue endocannabinoid system in human abdominal obesity
    • Nov;
    • Bluher M, Engeli S, Kloting N, et al. Dysregulation of the peripheral and adipose tissue endocannabinoid system in human abdominal obesity. Diabetes 2006 Nov; 55 (11): 3053-60
    • (2006) Diabetes , vol.55 , Issue.11 , pp. 3053-3060
    • Bluher, M.1    Engeli, S.2    Kloting, N.3
  • 14
    • 33847728280 scopus 로고    scopus 로고
    • Data on file, Sanofi-Aventis, 2006
    • Data on file, Sanofi-Aventis, 2006
  • 15
    • 0029034879 scopus 로고
    • Biochemical and pharmacological characterisation of SR141716A, the first potent and selective brain cannabinoid receptor antagonist
    • May 5;
    • Rinaldi-Carmona M, Barth F, Heaulme M, et al. Biochemical and pharmacological characterisation of SR141716A, the first potent and selective brain cannabinoid receptor antagonist. Life Sci 1995 May 5; 56: 1941-7
    • (1995) Life Sci , vol.56 , pp. 1941-1947
    • Rinaldi-Carmona, M.1    Barth, F.2    Heaulme, M.3
  • 16
    • 0028129936 scopus 로고
    • SR141716A, a potent and selective antagonist of the brain cannabinoid receptor
    • Rinaldi-Carmona M, Barth F, Heaulme M, et al. SR141716A, a potent and selective antagonist of the brain cannabinoid receptor. FEBS Lett 1994; 350 (2-3): 240-4
    • (1994) FEBS Lett , vol.350 , Issue.2-3 , pp. 240-244
    • Rinaldi-Carmona, M.1    Barth, F.2    Heaulme, M.3
  • 17
    • 24644500204 scopus 로고    scopus 로고
    • The CB1 receptor antagonist rimonabant reverses the diet-induced obesity phenotype through the regulation of lipolysis and energy balance
    • Jul 11;
    • Jbilo O, Ravinet-Trillou C, Arnone M, et al. The CB1 receptor antagonist rimonabant reverses the diet-induced obesity phenotype through the regulation of lipolysis and energy balance. FASEB J 2005 Jul 11; 19 (11): 1567-9
    • (2005) FASEB J , vol.19 , Issue.11 , pp. 1567-1569
    • Jbilo, O.1    Ravinet-Trillou, C.2    Arnone, M.3
  • 18
    • 9444265979 scopus 로고    scopus 로고
    • Potential modulation of plasma ghrelin and glucagon-like peptide-1 by anorexigenic cannabinoid compounds, SR141716A (rimonabant) and oleoylethanolamide
    • Nov;
    • Cani PD, Montoya ML, Neyrinck AM, et al. Potential modulation of plasma ghrelin and glucagon-like peptide-1 by anorexigenic cannabinoid compounds, SR141716A (rimonabant) and oleoylethanolamide. Br J Nutr 2004 Nov; 92 (5): 757-61
    • (2004) Br J Nutr , vol.92 , Issue.5 , pp. 757-761
    • Cani, P.D.1    Montoya, M.L.2    Neyrinck, A.M.3
  • 19
    • 12744260206 scopus 로고    scopus 로고
    • The anti-obesity effect of rimonabant is associated with an improved serum lipid profile
    • Jan;
    • Poirier B, Bidouard JP, Cadrouvele C, et al. The anti-obesity effect of rimonabant is associated with an improved serum lipid profile. Diabetes Obes Metab 2005 Jan; 7 (1): 65-72
    • (2005) Diabetes Obes Metab , vol.7 , Issue.1 , pp. 65-72
    • Poirier, B.1    Bidouard, J.P.2    Cadrouvele, C.3
  • 20
    • 31044456243 scopus 로고    scopus 로고
    • The cannabinoid CB1 receptor antagonist rimonabant (SR141716) inhibits cell proliferation and increases markers of adipocyte maturation in cultured mouse 3T3 F442A preadipocytes
    • Feb;
    • Gary-Bobo M, Elachouri G, Scatton B, et al. The cannabinoid CB1 receptor antagonist rimonabant (SR141716) inhibits cell proliferation and increases markers of adipocyte maturation in cultured mouse 3T3 F442A preadipocytes. Mol Pharmacol 2006 Feb; 69 (2): 471-8
    • (2006) Mol Pharmacol , vol.69 , Issue.2 , pp. 471-478
    • Gary-Bobo, M.1    Elachouri, G.2    Scatton, B.3
  • 21
    • 85047690626 scopus 로고    scopus 로고
    • The endogenous cennabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis
    • Cota D, Marsicano G, Tschop M, et al. The endogenous cennabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis. J Clin Invest 2003; 112 (3): 423-31
    • (2003) J Clin Invest , vol.112 , Issue.3 , pp. 423-431
    • Cota, D.1    Marsicano, G.2    Tschop, M.3
  • 22
    • 0035848818 scopus 로고    scopus 로고
    • Leptin-regulated endocannabinoids are involved in maintaining food intake
    • Apr 12;
    • Di Marzo V, Goparaju SK, Wang L, et al. Leptin-regulated endocannabinoids are involved in maintaining food intake. Nature 2001 Apr 12; 410 (6830): 822-5
    • (2001) Nature , vol.410 , Issue.6830 , pp. 822-825
    • Di Marzo, V.1    Goparaju, S.K.2    Wang, L.3
  • 23
    • 0035984946 scopus 로고    scopus 로고
    • Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: Stimulation of eating by 2-arachidonoyl glycerol
    • Kirkham TC, Williams CM, Fezza F, et al. Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: stimulation of eating by 2-arachidonoyl glycerol. Br J Pharmacol 2002; 136: 550-7
    • (2002) Br J Pharmacol , vol.136 , pp. 550-557
    • Kirkham, T.C.1    Williams, C.M.2    Fezza, F.3
  • 24
    • 19344376599 scopus 로고    scopus 로고
    • Suppression of conditioned nicotine and sucrose seeking by the cannabinoid-1 receptor antagonist SR141716A
    • Jun 3;
    • DeVries TJ, deVries W, Janssen MCW, et al. Suppression of conditioned nicotine and sucrose seeking by the cannabinoid-1 receptor antagonist SR141716A. Behav Brain Res 2005 Jun 3; 161 (1): 164-8
    • (2005) Behav Brain Res , vol.161 , Issue.1 , pp. 164-168
    • DeVries, T.J.1    deVries, W.2    Janssen, M.C.W.3
  • 25
    • 0030738512 scopus 로고    scopus 로고
    • Selective inhibition of sucrose and ethanol intake by SR 141716, an antagonist of central cannabinoid (CB1) receptors
    • Jul;
    • Arnone M, Maruani J, Chaperon F, et al. Selective inhibition of sucrose and ethanol intake by SR 141716, an antagonist of central cannabinoid (CB1) receptors. Psychopharmacology (Berl) 1997 Jul; 132: 104-6
    • (1997) Psychopharmacology (Berl) , vol.132 , pp. 104-106
    • Arnone, M.1    Maruani, J.2    Chaperon, F.3
  • 27
    • 2442433826 scopus 로고    scopus 로고
    • The cannabinoid CB1 antagonists SR 141716A and AM 251 suppress food intake and food-reinforced behavior in a variety of tasks in rats
    • Dec;
    • McLaughlin PJ, Winston K, Swezey L, et al. The cannabinoid CB1 antagonists SR 141716A and AM 251 suppress food intake and food-reinforced behavior in a variety of tasks in rats. Behav Pharmacol 2003 Dec; 14 (8): 583-8
    • (2003) Behav Pharmacol , vol.14 , Issue.8 , pp. 583-588
    • McLaughlin, P.J.1    Winston, K.2    Swezey, L.3
  • 28
    • 27844463517 scopus 로고    scopus 로고
    • Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia
    • Nov 17;
    • Despres JP, Golay A, Sjostrom L, et al. Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia. N Engl J Med 2005 Nov 17; 353 (20): 2121-34
    • (2005) N Engl J Med , vol.353 , Issue.20 , pp. 2121-2134
    • Despres, J.P.1    Golay, A.2    Sjostrom, L.3
  • 29
    • 0037304290 scopus 로고    scopus 로고
    • Anti-obesity effect of SR141716, a CB1 receptor antagonist, in diet-induced obese mice
    • Feb;
    • Ravinet Trillou C, Arnone M, Delgorge C, et al. Anti-obesity effect of SR141716, a CB1 receptor antagonist, in diet-induced obese mice. Am J Physiol Regul Integr Comp Physiol 2003 Feb; 284 (2): R345-53
    • (2003) Am J Physiol Regul Integr Comp Physiol , vol.284 , Issue.2
    • Ravinet Trillou, C.1    Arnone, M.2    Delgorge, C.3
  • 30
    • 33847767123 scopus 로고    scopus 로고
    • Acomplia: summary of product characteristics [online]. Available from URL: http://www.emea.eu.int/ [Accessed 2006 Jul 20]
    • Acomplia: summary of product characteristics [online]. Available from URL: http://www.emea.eu.int/ [Accessed 2006 Jul 20]
  • 31
    • 33847353496 scopus 로고    scopus 로고
    • Effect of orlistat on the pharmacokinetics of rimonabant [abstract]
    • Feb 1;
    • Turpault S, Woolfrey S, Lockwood GF, et al. Effect of orlistat on the pharmacokinetics of rimonabant [abstract]. Clin Pharmacol Ther 2006 Feb 1; 79 (2): 77
    • (2006) Clin Pharmacol Ther , vol.79 , Issue.2 , pp. 77
    • Turpault, S.1    Woolfrey, S.2    Lockwood, G.F.3
  • 32
    • 33847745416 scopus 로고    scopus 로고
    • Population pharmacokinetic analysis of rimonabant in healthy subjects [abstract no. PI-136]
    • Feb;
    • Ferron GM, Grandison M, Lockwood G. Population pharmacokinetic analysis of rimonabant in healthy subjects [abstract no. PI-136]. Clin Pharmacol Ther 2005 Feb; 77 (2): 43
    • (2005) Clin Pharmacol Ther , vol.77 , Issue.2 , pp. 43
    • Ferron, G.M.1    Grandison, M.2    Lockwood, G.3
  • 33
    • 33748350089 scopus 로고    scopus 로고
    • Rimonabant pharmacokinetics in healthy and obese subjects [abstract]
    • Turpault S, Kanamaluru V, Lockwood GF, et al. Rimonabant pharmacokinetics in healthy and obese subjects [abstract]. Clin Pharmacol Ther 2006; 79 (2): 50
    • (2006) Clin Pharmacol Ther , vol.79 , Issue.2 , pp. 50
    • Turpault, S.1    Kanamaluru, V.2    Lockwood, G.F.3
  • 34
    • 33847402793 scopus 로고    scopus 로고
    • Lack of effect of rimonabant on the pharmacokinetics of nicotine [abstract]
    • Turpault S, Kanamaluru V, Lockwood GF, et al. Lack of effect of rimonabant on the pharmacokinetics of nicotine [abstract]. Clin Pharmacol Ther 2006; 79 (2): 24
    • (2006) Clin Pharmacol Ther , vol.79 , Issue.2 , pp. 24
    • Turpault, S.1    Kanamaluru, V.2    Lockwood, G.F.3
  • 35
    • 33644878949 scopus 로고    scopus 로고
    • Lack of effect of rimonabant on the pharmacokinetics of digoxin [abstract]
    • Kanamaluru V, Lockwood G, Bonnet D, et al. Lack of effect of rimonabant on the pharmacokinetics of digoxin [abstract]. J Clin Pharmacol 2005; 45 (9): 1081
    • (2005) J Clin Pharmacol , vol.45 , Issue.9 , pp. 1081
    • Kanamaluru, V.1    Lockwood, G.2    Bonnet, D.3
  • 36
    • 33644913741 scopus 로고    scopus 로고
    • Lack of effect of rimonabant on the pharmacokinetics of oral contraceptives [abstract]
    • Kanamaluru V, Lockwood G, Bonnet D, et al. Lack of effect of rimonabant on the pharmacokinetics of oral contraceptives [abstract]. J Clin Pharmacol 2005; 45 (9): 1082
    • (2005) J Clin Pharmacol , vol.45 , Issue.9 , pp. 1082
    • Kanamaluru, V.1    Lockwood, G.2    Bonnet, D.3
  • 37
    • 33644913741 scopus 로고    scopus 로고
    • Lack of effect of rimonabant on the pharmacokinetics and pharmacodynamics of warfarin [abstract]
    • Grandison M, Kanamaluru V, Lockwood G, et al. Lack of effect of rimonabant on the pharmacokinetics and pharmacodynamics of warfarin [abstract]. J Clin Pharmacol 2005; 45 (9): 1082
    • (2005) J Clin Pharmacol , vol.45 , Issue.9 , pp. 1082
    • Grandison, M.1    Kanamaluru, V.2    Lockwood, G.3
  • 38
    • 33644913741 scopus 로고    scopus 로고
    • Lack of effect of rimonabant on the pharmacokinetics and pharmacodynamics of midazolam [abstract]
    • Grandison M, Kanamaluru V, Lockwood G, et al. Lack of effect of rimonabant on the pharmacokinetics and pharmacodynamics of midazolam [abstract]. J Clin Pharmacol 2005; 45 (9): 1082
    • (2005) J Clin Pharmacol , vol.45 , Issue.9 , pp. 1082
    • Grandison, M.1    Kanamaluru, V.2    Lockwood, G.3
  • 39
    • 33847727879 scopus 로고    scopus 로고
    • 2 year results [oral presentation]
    • Session of the American College of Cardiology; Mar 6-9; Orlando FL
    • Van Gaal L. Rio-Europe: 2 year results [oral presentation]. 54th Annual Scientific Session of the American College of Cardiology; 2005 Mar 6-9; Orlando (FL)
    • (2005) 54th Annual Scientific
    • Van Gaal, L.1    Rio-Europe2
  • 40
    • 17144382751 scopus 로고    scopus 로고
    • Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study
    • Apr 16;
    • Van Gaal LF, Rissanen AM, Scheen AJ, et al. Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study. Lancet 2005 Apr 16; 365 (9468): 1389-97
    • (2005) Lancet , vol.365 , Issue.9468 , pp. 1389-1397
    • Van Gaal, L.F.1    Rissanen, A.M.2    Scheen, A.J.3
  • 41
    • 32644441249 scopus 로고    scopus 로고
    • Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: a randomized controlled trial
    • Feb 15;
    • Pi-Sunyer FX, Aronne LJ, Heshmati HM, et al. Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: a randomized controlled trial. JAMA 2006 Feb 15; 295 (7): 761-75
    • (2006) JAMA , vol.295 , Issue.7 , pp. 761-775
    • Pi-Sunyer, F.X.1    Aronne, L.J.2    Heshmati, H.M.3
  • 43
    • 0035897696 scopus 로고    scopus 로고
    • Executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III)
    • Cleeman JI. Executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III). JAMA 2001; 285 (19): 2486-97
    • (2001) JAMA , vol.285 , Issue.19 , pp. 2486-2497
    • Cleeman, J.I.1
  • 44
    • 33847712969 scopus 로고    scopus 로고
    • Effect of rimonabant on systolic and diastolic blood pressure in overweight/obese patients with/without co-morbidities [abstract]
    • Jun 12-15; Madrid
    • Van Gaal L, Scheen A, Despres J-P, et al. Effect of rimonabant on systolic and diastolic blood pressure in overweight/obese patients with/without co-morbidities [abstract]. The 16th Scientific Meeting of the European Society of Hypertension; 2006 Jun 12-15; Madrid
    • (2006) The 16th Scientific Meeting of the European Society of Hypertension
    • Van Gaal, L.1    Scheen, A.2    Despres, J.-P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.