Impaired neutrophil chemotaxis in chronic obstructive pulmonary disease

American Journal of Respiratory and Critical Care Medicine

Volumn 175, Issue 5, 2007, Pages 473-479

  Yoshikawa, Takahiro ^a,b   Dent, Gordon ^a,c   Ward, Jon ^a   Angco, Gilbert ^a   Nong, Guangmin ^a   Nomura, Naho ^b   Hirata, Kazuto ^b   Djukanovic, Ratko ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c KEELE UNIVERSITY   (United Kingdom)

Author keywords

Chemotaxis; Chronic obstructive pulmonary disease; Neutrophils; Sputum

Indexed keywords

FORMYLMETHIONYLLEUCYLPHENYLALANINE; INTERLEUKIN 8;

ADULT; AGED; ARTICLE; CELL ISOLATION; CELL MIGRATION; CELL SURVIVAL; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE CLASSIFICATION; DISEASE COURSE; DISEASE SEVERITY; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; LUNG LAVAGE; MALE; NEUTROPHIL CHEMOTAXIS; NEUTROPHIL COUNT; PRIORITY JOURNAL; SMOKING; SPUTUM ANALYSIS; STATISTICAL ANALYSIS;

BRONCHOALVEOLAR LAVAGE FLUID; CHEMOTAXIS, LEUKOCYTE; FEMALE; HUMANS; INTERLEUKIN-8; LEUKOCYTE COUNT; MALE; MIDDLE AGED; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEUTROPHILS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SEVERITY OF ILLNESS INDEX; SPUTUM;

EID: 33847676891     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.200507-1152OC     Document Type: Article

References (52)

1. Saetta M. Airway inflammation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1999;160(Suppl):S17-S20.
2. Barnes PJ. Medical progress: chronic obstructive pulmonary disease. N Engl J Med 2000;343:269-280.
3. Rutgers SR, Timens W, Kaufmann HF, van der Mark TW, Koeter GH, Postma DS. Comparison of induced sputum with bronchial wash, bronchoalveolar lavage and bronchial biopsies in COPD. Eur Respir J 2000;15:109-115.
4. Martin TR, Raghu G, Maunder RJ, Springmeyer SC. The effects of chronic bronchitis and chronic air-flow obstruction on lung cell populations recovered by bronchoalveolar lavage. Am J Respir Crit Care Med 1985;132:254-260.
5. Hogg JC, Chu F, Utokaparch S, Woods R, Elliott WM, Buzatu L, Cherniak RM, Rogers RM, Sciurba FC, Coxson HO, et al. The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med 2005;350:2645-2653.
6. Keatings VM, Barnes PJ. Granulocyte activation markers in induced sputum: comparison between chronic obstructive pulmonary disease, asthma, and normal subjects. Am J Respir Crit Care Med 1997;155:449-453.
7. O'Donnell RA, Peebles C, Ward JA, Daraker A, Angco G, Broberg P, Pierrou S, Lund J, Holgate ST, Davies DE, et al. Relationship between peripheral airway dysfunction, airway obstruction, and neutrophilic inflammation in COPD. Thorax 2004;59:837-842.
8. Keatings VM, Collins PD, Scott DM, Barnes PJ. Differences in interleukin-8 and tumor necrosis factor-α in induced sputum from patients with chronic obstructive pulmonary disease or asthma. Am J Respir Crit Care Med 1996;153:530-534.
9. Traves SL, Culpitt SV, Russell RE, Barnes PJ, Donnelly LE. Increased levels of the chemokines GROα and MCP-1 in sputum samples from patients with COPD. Thorax 2002;57:590-595.
10. Yamamoto C, Yoneda T, Yoshikawa M, Fu A, Tokuyama T, Tsukaguchi K, Narita N. Airway inflammation in COPD assessed by sputum levels of interleukin-8. Chest 1997;112:505-510.
11. Richman-Eisenstat JBY, Jorens PG, Hebert CA, Ueki I, Nadel JA. Interleukin-8: an important chemoattractant in sputum of patients with chronic inflammatory airway diseases. Am J Physiol 1993;264: L413-L418.
12. Mikami M, Llewellyn-Jones CG, Bayley D, Hill SL, Stockley RA. The chemotactic activity of sputum from patients with bronchiectasis. Am J Respir Crit Care Med 1998;157:723-728.
13. 4 and interleukin 8. Thorax 2002;57:709-714.
14. 4. Chest 2003;123:1240-1247.
15. 4. Eur Respir J 2000;15:274-280.
16. Fletcher C, Peto R. The natural history of chronic airflow obstruction. BMJ 1977;1:1645-1648.
17. O'Donnell RA, Richter A, Ward J, Angco G, Mehta A, Rousseau K, Swallow DM, Holgate ST, Djukanovic R, Davies DE, et al. Expression of ErbB receptors and mucins in the airways of long term current smokers. Thorax 2004;59:1032-1040.
18. Pauwels RA, Buist AS, Calverley PMA, Jenkins CR, Hurd SS. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) workshop summary. Am J Respir Crit Care Med 2001;163:1256-1276.
19. National Heart, Lung, and Blood Institute. Global Initiative for Chronic Obstructive Lung Disease: global strategy for diagnosis, management, and prevention of chronic obstructive pulmonary disease (2004 update). Bethesda, MD: National Institutes of Health; 2004.
20. Paggiaro PL, Chanez P, Holz O, Ind PW, Djukanovic R, Maestrelli P, Sterk PJ. Sputum induction. Eur Respir J 2002;3s-8s.
21. Hadjicharalambous C, Dent G, May RD, Handy RLC, Anderson IK, Davies DE, Djukanovic R. Measurement of eotaxin (CCL11) in induced sputum supernatants: validation and detection in asthma. J Allergy Clin Immunol 2004;113:657-662.
22. Böyum A. Isolation of mononuclear cells and granulocytes from human blood: isolation of mononuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. Scand J Clin Lab Invest 1968;77-89.
23. Haslett C, Guthrie LA, Kopaniak MM, Johnson RB Jr, Henson PM. Modulation of multiple neutrophil functions by preparative methods or trace concentrations of bacterial lipopolysaccharide. Am J Pathol 1985;119:101-110.
24. Taylor ML, Dastych J, Sehgal D, Sundstrom M, Nilsson G, Akin C, Mage RG, Metcalfe DD. The Kit-activating mutation D816V enhances stem cell factor-dependent chemotaxis. Blood 2001;98:1195-1199.
25. Burnett D, Chamba A, Hill SL, Stockley RA. Neutrophils from subjects with chronic obstructive lung disease show enhanced chemotaxis and extracellular proteolysis. Lancet 1987;2:1043-1046.
26. Stockley RA, Grant RA, Llewellyn-Jones CG, Hill SL, Burnett D. Neutrophil formyl-peptide receptors: relationship to peptide-induced responses and emphysema. Am J Respir Crit Care Med 1994;149:464-468.
27. Nowak D, Ruta U, Piasecka G. Nicotine increases human polymorphonuclear leukocytes chemotactic response: a possible additional mechanism of lung injury in cigarette smokers. Exp Pathol 1990;39:37-43.
28. Dent G, Hadjicharalambous C, Yoshikawa T, Handy RLC, Powell J, Anderson IK, Louis R, Davies DE, Djukanovic R. Contribution of eotaxin-1 to eosinophil chemotactic activity of moderate and severe asthmatic sputum. Am J Respir Crit Care Med 2004;169:1110-1117.
29. Frevert CW, Wong VA, Goodman RB, Goodwin R, Martin TR. Rapid, fluorescence-based measurement of neutrophil migration in vitro. J Immunol Methods 1998;213:41-52.
30. Tanaka S, Robinson EA, Yoshimura T, Matsushima K, Leonard EJ, Appella E. Synthesis and biological characterization of monocyte-derived neutrophil chemotactic factor. FEBS Lett 1998;236:467-470.
31. Showell HJ, Freer RJ, Zigmond SH, Schiffman E, Aswaikumar S, Corcoran B, Becker EL. The structure-activity relations of synthetic peptides as chemotactic factors and inducers of lysosomal secretion for neutrophils. J Exp Med 1976;143:1154-1169.
32. Fietta A, Bersani C, De Rose V, Grassi FA, Mangiarotti P, Uccelli M, Grassi C. Evaluation of systemic host defense mechanisms in chronic bronchitis. Respiration 1988;53:37-43.
33. Robbins RA, Gossman GL, Nelson KJ, Koyama S, Thompson AB, Rennard SI. Inactivation of chemotactic factor inactivator by cigarette smoke: a potential mechanism of modulating neutrophil recruitment to the lung. Am Rev Respir Dis 1990;142:763-768.
34. Marshall LJ, Perks B, Ferkol T, Shute JK. IL-8 released constitutively by primary bronchial epithelial cells in culture forms an inactive complex with secretory component. J Immunol 2001;167:2816-2823.
35. Hodge S, Hodge G, Scicchitano R, Reynolds PN, Holmes M. Alveolar macrophages from subjects with chronic obstructive pulmonary disease are deficient in their ability to phagocytose apoptotic airway epithelial cells. Immunol Cell Biol 2003;81:289-296.
36. Hodge S, Hodge G, Holmes M, Reynolds PN. Increased airway epithelial and T-cell apoptosis in COPD remains despite smoking cessation. Eur Respir J 2005;25:447-454.
37. Pons J, Sauleda J, Ferrer JM, Barcelo B, Fuster A, Regueiro V, Julia MR, Agusti AG. Blunted γδ T-lymphocyte response in chronic obstructive pulmonary disease. Eur Respir J 2005;25:441-446.
38. Jameson J. T-cell effector mechanisms: γδ and CD1d-restricted subsets. Curr Opin Immunol 2003;15:349-353.
39. Pons AR, Noguera A, Blanquer D, Sauleda J, Pons J, Agusti AG. Phenotypic characterisation of alveolar macrophages and peripheral blood monocytes in COPD. Eur Respir J 2005;25:647-652.
40. Aarbio J, van Schadewijk A, Stolk J, Sont JK, de Boer WI, Rabe KF, van Krieken JHJM, Mauad T, Hiemstra PS. Human neutrophil defensins and secretory leukocyte proteinase inhibitor in squamous metaplastic epithelium of bronchial airways. Inflamm Res 2004;53:230-238.
41. Woolhouse IS, Bayley DL, Lalor P, Adams DH, Stockley RA. Endothelial interactions of neutrophils under flow in chronic obstructive pulmonary disease. Eur Respir J 2005;25:612-617.
42. Haslett C. Granulocyte apoptosis and its roles in the resolution and control of lung inflammation. Am J Respir Crit Care Med 1999;160:S5-S11.
43. Whyte MKB, Meagher LC, Hardwick SJ, Savill JS, Haslett C. Transient elevations of cytosolic free calcium retard subsequent apoptosis in neutrophils in vitro. J Clin Invest 1993;92:446-455.
44. Rossi AG, Cousin JM, Dransfield I, Lawson MF, Chilvers ER, Haslett C. Agents that elevate cAMP inhibit human neutrophil apoptosis. Biochem Biophys Res Commun 1995;217:892-899.
45. Monso E, Ruiz J, Rosell A, Manterola J, Fiz J, Morera J, Ausina V. Bacterial infection in chronic obstructive pulmonary disease: a study of stable and exacerbated outpatients using the protected specimen brush. Am J Respir Crit Care Med 1995;152:1316-1320.
46. Monso E, Rosell A, Bonet G, Manterola J, Cardona PJ, Ruiz J, Morera J. Risk factors for lower airway bacterial colonization in chronic bronchitis. Eur Respir J 1999;13:338-342.
47. Zalacain R, Sobradillo V, Amilibia J, Barron J, Achotegui V, Pijoan JI, Llorente JL. Predisposing factors to bacterial colonization in chronic obstructive pulmonary disease. Eur Respir J 1999;13:343-348.
48. Patel IS, Seemungal TA, Wilks M, Lloyd-Owen SJ, Donaldson GC, Wedzicha JA. Relationship between bacterial colonisation and the frequency, character, and severity of COPD exacerbations. Thorax 2002;57:759-764.
49. Hill AT, Campbell EJ, Sill SL, Bayley DL, Stockley RA. Association between airway bacterial load and markers of airway inflammation in patients with stable chronic bronchitis. Am J Med 2000;109:288-295.
50. Heit B, Tavener S, Raharjo E, Kubes P. An intracellular signalling hierarchy determines direction of migration in opposing chemotactic gradients. J Cell Biol 2002;159:91-102.
51. Sethi S, Murphy TF. Bacterial infection in chronic obstructive pulmonary disease in 2000: a state-of-the-art review. Clin Microbiol Rev 2001;14:336-363.
52. 1 decline in patients with chronic obstructive pulmonary disease. Am J Respir Respir Crit Care Med 2003;167:1090-1095.