In utero-initiated cancer: The role of reactive oxygen species

Birth Defects Research Part C - Embryo Today: Reviews

Volumn 78, Issue 4, 2006, Pages 326-332

  Wan, Joanne ^a   Winn, Louise M ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

Benzene; Carcinogenesis; Cigarette smoke; Diethylstilbestrol; DNA damage; In utero; Reactive oxygen species; Signal transduction

Indexed keywords

2 BUTANONE; 4 (METHYLNITROSAMINE) 1 (3 PYRIDYL) 1 BUTANONE; BENZENE; BIOLOGICAL MARKER; CARCINOGEN; CIGARETTE SMOKE; DIETHYLSTILBESTROL; ENVIRONMENTAL CHEMICAL; NITROSAMINE; POLYCYCLIC AROMATIC HYDROCARBON; PYRIDINE DERIVATIVE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; XENOBIOTIC AGENT; ZIDOVUDINE;

CANCER; CARCINOGENESIS; CONGENITAL MALFORMATION; DISEASE MARKER; DNA DAMAGE; ENVIRONMENTAL EXPOSURE; EXON; FETUS DEVELOPMENT; FUNCTIONAL DISEASE; GENE DELETION; GENE EXPRESSION; GENE MUTATION; HUMAN; NONHUMAN; OXIDATIVE STRESS; PRENATAL EXPOSURE; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; CHILD; DNA DAMAGE; FEMALE; HUMANS; NEOPLASMS; OXIDATIVE STRESS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SMOKING; XENOBIOTICS;

EID: 33847664708     PISSN: 1542975X     EISSN: None     Source Type: Journal    
DOI: 10.1002/bdrc.20080     Document Type: Review

References (84)

1. Albertini RJ. 2001. HPPT mutations in humans: biomarkers for mechanistic studies. Mutat Res 489:1-16.
2. Ammenheuser MM, Berenson AB, Stiglich, et al. 1994. Elevated frequencies of hprt mutant lymphocytes in cigarette-smoking mothers and their newborns. Mutat Res 304:285-294.
3. Anderson LM. 2006. Environmental genotoxicants/carcinogens and childhood cancer: bridgeable gaps in scientific knowledge. Mutat Res 608:136-156.
4. Bialkowska A, Bialkowski K, Gershenson M, et al. 2000. Oxidative DNA damage in fetal tissues after transplacental exposure to 3′-azido- 3′-deoxythymidine (AZT). Carcinogenesis 21:1059-1062.
5. Block K, Kardana A, Igarashi P, et al. 2000. In utero diethylstilbestrol (DES) exposure alters Hox gene expression in the developing mullerian system. FASEB J 14:1101-1108.
6. Braithwaite E, Wu X, Wang Z. 1998. Repair of DNA lesions: mechanisms and relative repair efficiencies. Mutat Res 424:207-219.
7. Brondum J, Shu XO, Steinbuch M, et al. 1999. Parental cigarette smoking and the risk of acute leukemia in children. Cancer 85:1380-1388.
8. Buckley JD, Robison LL, Swotinsky R, et al. 1989. Occupational exposures of parents of children with acute nonlymphocytic leukemia: a report from the Children's Cancer Study Group. Cancer Res 49:4030-4037.
9. Byers VS, Levin AS, Ozonoff DM, et al. 1988. Association between clinical symptoms and lymphocyte abnormalities in a population with chronic domestic exposure to industrial solvent-contaminated domestic water supply and a high incidence of leukemia. Cancer Immunol Immunother 27:77-81.
10. Chanda S, Dasgupta UB, Guhamazumder D, et al. 2006. DNA hypermethylation of promoter of gene p53 and p16 in arsenic-exposed people with and without malignancy. Tox Sci 89:431-437.
11. Chen CS, Wells PG. 2004. In utero origins of cancer: maternal dietary vitamin E, fetal oxidative DNA damage, and postnatal carcinogenesis in p53 knockout mice. Ann NY Acad Sci 1031:395-398.
12. Ciranni R, Barale R, Marrazzini A, et al. 1988. Benzene and the genotoxicity of its metabolites. I. Transplacental activity in mouse fetuses and in their dams. Mutat Res 208:61-67.
13. Coghlin J, Gann PH, Hammond K, et al. 1991. 4-Aminobiphenyl hemoglobin adducts in fetuses exposed to the tobacco smoke carcinogen in utero. J Natl Cancer Inst 83:274-280.
14. Faiola B, Fuller ES, Wong VA, et al. 2004. Gene expression profile in bone marrow and hematopoietic stem cells in mice exposed to inhaled benzene. Mutat Res 549:195-212.
15. Fantel AG. 1996. Reactive oxygen species in developmental toxicity: review and hypothesis. Teratology 53:196-217.
16. Fasching K, Panzer S, Mass OA, et al. 2000. Presence of clone-specific antigen receptor gene rearrangements at birth indicates an in utero origin of diverse types of early childhood acute lymphoblastic leukemia. Blood 95:2722-2724.
17. Ford AM, Ridge SA, Cabrera ME, et al. 1993. In utero rearrangements in the trithorax-related oncogene in infant leukemias. Nature 363:358-360.
18. Ford AM, Pombo-de-Oliveria MS, McCarthy KP, et al. 1997. Monoclonal origin of concordant T-cell malignancy in identical twins. Blood 89:281-285.
19. Fratelli M, Goodwin LO, Orom UA, et al. 2005. Gene expression profiling reveals a signaling role of glutathione in redox regulation. Proc Natl Acad Sci USA 102:13998-14003.
20. Golding BT, Watson WP. 1999. Possible mechanisms of carcinogenesis after exposure to benzene. IARC Sci Publ 150:75-88.
21. Grant SG. 2005. Qualitatively and quantitatively similar effects of active and passive maternal tobacco smoke exposure on in utero mutagenesis at the HPRT locus. BMC Pediatr 5:1-8.
22. Gued LR, Thomas RD, Green R. 2003. Diallyl sulfide inhibits diethylstilbestrol-induced lipid peroxidation in breast tissue of female ACI rats: implications in breast cancer prevention. Oncol Rep 10:739-743.
23. Hales BF. 2005. DNA repair disorders causing malformations. Curr Opin Genet Dev 15:234-240.
24. Harris JE. 1996. Cigarette smoke components and disease: cigarette smoke is more than a triad of tar, nicotine, and carbon monoxide [Chapter 5]. In: The FTC cigarette test method for determining tar, nicotine, and carbon monoxide yields of U.S. Cigarettes: Report of the NCI Expert Committee, Monograph 7. Publisher: National Cancer Institute, Bethesda, MD. pp. 59-70.
25. Hecht SS. 1999. Tobacco smoke carcinogens and lung cancer. J Natl Cancer Inst 91:1194-1210.
26. Herbst AL, Ufelder AL, Poskanzer DC. 1971. Adenocarcinoma of the vagina. Association of maternal stilbestrol therapy with tumour appearance in young women. N Engl J Med 284:878-881.
27. Huffman D, Huffman I. 1997. The changing cigarette, 1950-1995. J Toxicol Environ Health 50:307-364.
28. Hong HH, Dunnick J, Herbert R, et al. Genetic alterations in K-ras and p53 cancer genes in lung neoplasms from Swiss (CD-1) male mice exposed transplacentally to AZT. Environ Mol Mutagen (in press).
29. Houstis N, Rosen ED, Lander ES. 2006. Reactive oxygen species have a causal role in multiple forms of insulin resistance. Nature 440:944-948.
30. Izzotti A, Balansky RM, Cartiglia C, et al. 2003. Genomic and transcriptional alterations in mouse fetal liver after transplacental exposure to cigarette smoke. FASEB J 17:1127-1129.
31. Keller KA, Snyder CA. 1986. Mice exposed in utero to low concentrations of benzene exhibit enduring changes in their colony forming hematopoietic cells. Toxicology 42:171-181.
32. Keller KA, Snyder CA. 1988. Mice exposed in utero to 20 ppm benzene exhibit altered numbers of recognizable hematopoietic cells up to seven weeks after exposure. Fund Appl Toxicol 10:224-232.
33. Keohavong P, Xi L, Day R, et al. 2005. HPRT gene alterations in umbilical cord blood T-lymphocytes in newborns of mothers exposed to tobacco smoke during pregnancy. Mutat Res 572:156-166.
34. Kishi R, Katakura Y, Yuasa J, et al. 1993. Association of parents' occupational exposure to cancer in children: a case-control study of acute lymphoblastic leukemia. Sangyo Igaku 35:515-529. [Japanese]
35. Lackmann GM, Salzberger U, Tollner U, et al. 1999. Metabolites of a tobacco specific carcinogen in urine from newborns. J Natl Cancer Inst 91:459-465.
36. Leverson JD, Koskinen PJ, Orrico FC. 1998. Pim-1 kinase and p100 cooperate to enhance c-Myb activity. Mol Cell 2:417-425.
37. Li S, Hansman R, Newbold R, et al. 2003. Neonatal diethylstilbestrol exposure induces persistent elevation of c-fos expression and hypomethylation in its exon-4 in mouse uterus. Mol Carcinogenesis 38:78-84.
38. Lindahl T, Wood RD. 1999. Quality control by DNA repair. Science 286:1897-1905.
39. Liu J, Xie Y, Ducharme DMK, et al. 2006. Global gene expression associated with hepatocarcinogenesis in adult male mice induced by in utero arsenic exposure. Environ Health Perspect 114:404-411.
40. Lopez-Neblina F, Toledo-Pereyra LH. 2006. Phosphoregulation of signal transduction pathways in ischemia and reperfusion. J Surg Res 134:292-299.
41. McKinney PA, Alexander FE, Cartwright RA, et al. 1991. Parental occupations of children with leukaemia in West Cumbria, North Humberside, and Gateshead. BMJ 302:681-687.
42. Menegaux F, Baruchel A, Betrand Y, et al. 2006. Household exposure to pesticides and risk of childhood acute leukaemia. Occup Environ Med 63:131-134.
43. Miller C, Denghart J, Sassoon DA. 1998. Fetal exposure to DES results in de-regulation of Wnt7a during uterine morphogenesis. Nat Genet 20:228-230.
44. Mittal M, Flora SJS. 2006. Effects of individual and combined exposure to sodium arsenite and sodium fluoride on tissue oxidative stress, arsenic and fluoride levels in male mice. Chem Biol Interact 162:128-139.
45. Mucci LA, Granath F, Cnattingius S. 2004. Maternal smoking and childhood leukemia and lymphoma risk among 1,440,542 Swedish children. Cancer Epidemiol Biomarkers Prev 13:1528-1533.
46. Ness SA. 1999 Myb binding proteins: regulators and cohorts in transformation. Oncogene 18:3039-3046.
47. Ning H, Kado NY, Kuzmicky PA, et al. 1991. Benzene-induced micronuclei formation in mouse fetal liver blood, peripheral blood, and maternal bone marrow cells. Environ Mol Mutat 18:1-5.
48. Nunomura A, Castellani RJ, Zhu X, et al. 2006. Involvement of oxidative stress in Alzheimer disease. J Neuropathol Exp Neurol 65:631-641.
49. Olivero OA, Anderson LM, Diwan BA, et al. 1997. Transplacental effects of 3′azido-2′,3′dideoxythymidine (AZT): tumorigenicity in mice and genotoxicity in mice and monkeys. J Natl Cancer Inst 89:1602-1608.
50. Olivero OA, Shearer GM, Chougnet CA, et al. 1999. Incorporation of zidovudine into leukocyte DNA from HIV-1 positive adults and pregnant women, and cord blood from infants exposed in utero. AIDS 13:919-925.
51. Pang D, McNally R, Birch JR. 2003. Parental smoking and childhood cancer: results from the United Kingdom childhood cancer study. Br J Cancer 88:373-381.
52. Petridou E, Trichopoulos D, Kalapothaki V, et al. 1997. The risk profile of childhood leukaemia in Greece: a nationwide case-control study. Br J Cancer 76:1241-1247.
53. Poirier MC, Olivero OA, Walker DM, et al. 2004. Perinatal genotoxicity and carcinogenicity of anti-retroviral nucleoside analog drugs. Toxicol Appl Pharmacol 199:151-161.
54. Rolo AP, Palmiera CM. 2006. Diabetes and mitochondrial function: role of hyperglycemia and oxidative stress. Toxicol Appl Pharmacol 212:167-178.
55. Roy D, Floyd RA, Liehr JG. 1991. Elevated 8-hydroxydeoxyganosine levels in DNA of diethylstilbestrol-treated Syrian hamsters: covalent DNA damage by free radicals generated by redox cycling of diethylstilbestrol. Cancer Res 51:3882-3885.
56. Roy D, Liehr JG. 1999. Estrogen, DNA damage and mutations. Mutat Res 424:107-115.
57. Sato J, Fukata H, Kogo Y, et al. 2006. Neonatal exposure to diethylstilbestrol alters the expression of DNA methyltransferases and methylation of genomic DNA in the epididymis of mice. Endocr J 53:331-337.
58. Schuller HM, Jorquera R, Reichert A, et al. 1993. Transplacental induction of pancreas tumors in hamsters by ethanol and the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Cancer Res 53:2498-2501.
59. Shu XO, Gao YT, Brinton LA, et al. 1988. A population-based case-control study of childhood leukemia in Shanghai. Cancer 62:635-644.
60. Shu XO, Ross JA, Pendergrass TW, et al. 1996. Parental alcohol consumption, cigarette smoking, and risk of infant leukemia: a children's cancer group study. J Natl Cancer Inst 88:254-231.
61. Sinnett D, Labuda D, Krajinovic M. 2006. Challenges identifying genetic determinants of pediatric cancers-the childhood leukemia experience. Fam Cancer 5:35-47.
62. Sipowicz MA, Amin S, Desai D, et al. 1997. Oxidative DNA damage in tissues of pregnant female mice and fetuses caused by the tobacco-specific nitrosamine, 4-(methylnitrosamine)-1-(3-pyridyl)-1-butanone (NNK). Cancer Lett 117:87-91.
63. Smith AH, Marshsall G, Yuan, et al. 2006. Increased mortality from lung cancer and bronchiectasis in young adults after exposure to arsenic in utero and in early childhood. Environ Health Perspect 114:1293-1296.
64. Steffen C, Auclerc MF, Auvrignon A, et al. 2004. Acute childhood leukaemia and environmental exposure to potential sources of benzene and other hydrocarbons; a case-control study. Occup Environ Med 61:773-778.
65. Steward A, Webb J, Giles D, et al. 1956. Malignant disease in childhood and diagnostic irradiation in utero. Lancet 2:447.
66. Steward A, Webb J, Hewitt D. 1958. A survey of childhood malignancies. Br Med 328:1495-1507.
67. Taylor HS, Vanden Heuvel G, Igarashi P. 1997. A conservative hox axis in the mouse and human reproductive system: late establishment and persistent expression of the hoxa cluster genes. Biol Reprod 57:1338-1345.
68. Valinluck V, Tsai H-H, Rogstad DK, et al. 2004. Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2). Nucleic Acids Res 32:4100-4108.
69. Valko M, Rhodes CJ, Moncol J, et al. 2006. Free radicals, metals and anti-oxidants in oxidative stress-induced cancer. Chem Biol Interact 160:1-40.
70. Van Steenel-Moll HA, Valkenburg HA, van Zangen GE. 1985. Childhood leukemia and parental occupation. A reg ister-based case-control study. Am J Epidemiol 121:216-224.
71. Vinson RK, Hales BF. 2002. DNA repair during organogenesis. Mutat Res 509:79-81.
72. Waalkes MP, Ward JM, Liu J, et al. 2003. Transplacental carcinogenicity of inorganic arsenic in the drinking water: induction of hepatic, ovarian, pulmonary, and adrenal tumors in mice. Toxicol Appl Pharmacol 186:7-17.
73. Waalkes MP, Liu J, Ward JM, et al. 2006. Enhanced urinary bladder and liver carcinogenesis in male CD1 mice exposed to transplacental inorganic arsenic and postnatal diethylstilbestrol or tamoxifen. Toxicol Appl Pharmacol 215:296-305.
74. Wan J, Winn LM. 2004. The effects of the benzene metabolites phenol and catechol on c-Myb and Pim-1 signalling in HD-3 cells. Toxicol Appl Pharmacol 201:194-201.
75. Wan J, Winn LM. 2006.Benzene alters embryonic Pim-1 signaling and induces oxidative stress in CD-1 mice. Proceedings of the 46th Annual Meeting of The Teratology Society. Birth Defects Res A 76:327.
76. Wang Z, Bhattacharya N, Weaver M, et al. 2001. Pim-1: a serine/threonine kinase with a role in cell survival, proliferation, differentiation and tumorigenesis. J Vet Sci 2:167-179.
77. Wells PG, Winn LM. 1996. Biochemical toxicology of chemical teratogenesis. Crit Rev Biochem Mol Biol 31:1-40.
78. Wells PG, Winn LM. 1997.The role of biotransformation in development toxicity [Chapter 40]. In: Boekelheide K, Chaplin RE, Hoyer PB, Harrs C, editors. Comprehensive toxicology, Vol. 10. Reproductive and endocrine toxicology. Oxford, UK: Pergamon Elsevier Science Ltd. pp. 470-497.
79. Wells PG, Kim PM, Laposa RR, et al. 1997. Oxidative damage in chemical teratogenesis. Mutat Res 396:65-78.
80. Wells PG, Bhuller Y, Chen CS, et al. 2005. Molecular and biochemical mechanisms in teratogenesis involving reactive oxygen species. Toxicol Appl Pharmacol 207(Suppl):354-366.
81. Wiemels JL, Cazzaniga G, Daniotti M, et al. 1999. Prenatal origin of acute lymphoblastic leukaemia in children. Lancet 354:1499-1503.
82. Winn LM, Wells PG. 1995. Free radical-mediated mechanisms of chemical teratogenesis. Eur 3 Neurology 2(Suppl 4):5-29.
83. Winn LM. 2003. Homologous recombination initiated by benzene metabolites: a potential role of oxidative stress. Toxicol Sci 72:143-149.
84. Winn LM, Lei W, Ness SA. 2003. Pim-1 phosphorylates the DNA binding domain of c-Myb. Cell Cycle 2:258-262.