Role of the amygdala in ethanol withdrawal seizures

Brain Research

Volumn 1141, Issue 1, 2007, Pages 65-73

  Feng, Hua Jun ^a   Yang, Li ^a   Faingold, Carl L ^a  

^a SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Amygdala; Binge ethanol; Ethanol withdrawal seizure; Neuronal firing

Indexed keywords

2 AMINO 7 PHOSPHONOHEPTANOIC ACID; ALCOHOL; N METHYL DEXTRO ASPARTIC ACID;

ACTION POTENTIAL; AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUDIOGENIC SEIZURE; AUDITORY RESPONSE; CANNULATION; CONVULSION; ELECTRODE; MALE; MICROINJECTION; NERVE CELL; NERVE CELL NETWORK; NONHUMAN; PRIORITY JOURNAL; RAT; WITHDRAWAL SEIZURE;

2-AMINO-5-PHOSPHONOVALERATE; ACOUSTIC STIMULATION; ACTION POTENTIALS; ALCOHOL WITHDRAWAL SEIZURES; AMYGDALA; ANIMALS; BEHAVIOR, ANIMAL; CENTRAL NERVOUS SYSTEM DEPRESSANTS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELECTROENCEPHALOGRAPHY; ETHANOL; EXCITATORY AMINO ACID ANTAGONISTS; MALE; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS; RODENTIA;

EID: 33847648944     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2007.01.017     Document Type: Article

References (68)

1. Arendt T., Henning D., Gray J.A., and Marchbanks R. Loss of neurons in the rat basal forebrain cholinergic projection system after prolonged intake of ethanol. Brain Res. Bull. 21 (1988) 563-569
2. B receptors. J. Neurosci. 24 (2004) 10679-10686
3. Bhave S.V., Snell L.D., Tabakoff B., and Hoffman P.L. Mechanism of ethanol inhibition of NMDA receptor function in primary cultures of cerebral cortical cells. Alcohol.: Clin. Exp. Res. 20 (1996) 934-941
4. Calton J.L., Wilson W.A., and Moore S.D. Magnesium-dependent inhibition of N-methyl-d-aspartate receptor-mediated synaptic transmission by ethanol. J. Pharmacol. Exp. Ther. 287 (1998) 1015-1019
5. Chakravarty D.N., and Faingold C.L. Comparison of neuronal response patterns in the external and central nuclei of inferior colliculus during ethanol administration and ethanol withdrawal. Brain Res. 783 (1998) 102-108
6. Chakravarty D.N., and Faingold C.L. Differential roles in the neuronal network for audiogenic seizures are observed among the inferior colliculus subnuclei and the amygdala. Exp. Neurol. 157 (1999) 135-141
7. Chandler L.J., Carpenter-Hyland E., Hendricson A.W., Maldve R.E., Morrisett R.A., Zhou F.C., Sari Y., Bell R., and Szumlinski K.K. Structural and functional modifications in glutamatergic synapses following prolonged ethanol exposure. Alcohol.: Clin. Exp. Res. 30 2 (2006) 368-376
8. Chang S.L., Patel N.A., and Romero A.A. Activation and desensitization of Fos immunoreactivity in the rat brain following ethanol administration. Brain Res. 679 (1995) 89-98
9. Clemmesen L., Ingvar M., Hemmingsen R., and Bolwig T.G. Local cerebral glucose consumption during ethanol withdrawal in the rat: effects of single and multiple episodes and previous convulsive seizures. Brain Res. 453 (1988) 204-214
10. Criado J.R., and Morales M. Acute ethanol induction of c-Fos immunoreactivity in pre-pro-enkephalin expressing neurons of the central nucleus of the amygdale. Brain Res. 861 (2000) 173-177
11. Devaud L.L., and Alele P. Differential effects of chronic ethanol administration and withdrawal on γ-aminobutyric acid type A and NMDA receptor subunit proteins in male and female rat brain. Alcohol.: Clin. Exp. Res. 28 (2004) 957-965
12. Eckardt M.J., Campbell G.A., Marietta C.A., Majchrowicz E., Wixon H.N., and Weight F.F. Cerebral 2-deoxyglucose uptake in rats during ethanol withdrawal and postwithdrawal. Brain Res. 366 (1986) 1-9
13. Engberg G., and Hajös M. Alcohol withdrawal reaction as a result of adaptive changes of excitatory amino acid receptors. Naunyn-Schmiedeberg's Arch. Pharmacol. 346 (1992) 437-441
14. Faingold C.L. Neuronal networks in the genetically epilepsy-prone rat. Adv. Neurol. 79 (1999) 311-321
15. Faingold C.L., and Anderson C.A. Loss of intensity-induced inhibition in inferior colliculus neurons leads to audiogenic seizure susceptibility in behaving genetically epilepsy-prone rats. Exp. Neurol. 113 (1991) 354-363
16. Faingold C.L., and Randall M. Ethanol withdrawal seizures-role of dentate gyrus neurons. Alcohol: Clin. Exp. Res. 30 (2006) 78A (S)
17. Faingold C.L., and Riaz A. Increased responsiveness of pontine reticular formation neurons associated with audiogenic seizure susceptibility during ethanol withdrawal. Brain Res. 663 (1994) 69-76
18. Faingold C.L., and Riaz A. Ethanol withdrawal induces increased firing in inferior colliculus neurons associated with audiogenic seizure susceptibility. Exp. Neurol. 132 (1995) 91-98
19. Faingold C.L., N'Gouemo P., and Riaz A. Ethanol and neurotransmitter interactions-from molecular to integrative effects. Prog. Neurobiol. 55 (1998) 509-535
20. Faingold C.L., Knapp D.J., Chester J.A., and Gonzalez L.P. Integrative neurobiology of the alcohol withdrawal syndrome-from anxiety to seizures. Alcohol.: Clin. Exp. Res. 28 (2004) 268-278
21. Feng H.J., and Faingold C.L. Modulation of audiogenic seizures by histamine and adenosine receptors in the inferior colliculus. Exp. Neurol. 163 (2000) 264-270
22. Feng H.J., and Faingold C.L. Repeated generalized audiogenic seizures induce plastic changes on acoustically evoked neuronal firing in the amygdala. Brain Res. 932 (2001) 61-69
23. Feng H.J., and Faingold C.L. Synaptic plasticity in the pathway from the medial geniculate body to the lateral amygdala is induced by seizure repetition. Brain Res. 946 (2002) 198-205
24. Feng H.J., Naritoku D.K., Randall M.E., and Faingold C.L. Modulation of audiogenically kindled seizures by γ-aminobutyric acid-related mechanisms in the amygdala. Exp. Neurol. 172 (2001) 477-481
25. Floyd D.W., Jung K.Y., and McCool B.A. Chronic ethanol ingestion facilitates N-methyl-d-aspartate receptor function and expression in rat lateral/basolateral amygdala neurons. J. Pharmacol. Exp. Ther. 307 (2003) 1020-1029
26. A receptors in basolateral amygdala. J. Pharmacol. Exp. Ther. 311 (2004) 1071-1079
27. Fröhlich R., Patzelt C., and Illes P. Inhibition by ethanol of excitatory amino acid receptors and nicotinic acetylcholine receptors at rat locus coeruleus neurons. Naunyn-Schmiedeberg's Arch. Pharmacol. 350 (1994) 626-631
28. Frye G.D., McCown T.J., Breese G.R., and Peterson S.L. GABAergic modulation of inferior colliculus excitability: role in the ethanol withdrawal audiogenic seizures. J. Pharmacol. Exp. Ther. 237 (1986) 478-485
29. Garcia-Cairasco N. A critical review on the participation of inferior colliculus in acoustic-motor and acoustic-limbic networks involved in the expression of acute and kindled audiogenic seizures. Hear. Res. 168 1-2 (2002) 208-222
30. Gonzalez L.P., Veatch L.M., Ticku M.K., and Becker H.C. Alcohol withdrawal kindling: mechanisms and implications for treatment. Alcohol.: Clin. Exp. Res. 25 (2001) 197S-201S (Suppl. ISBRA)
31. A responses in cells stably transfected with receptor subunits. Alcohol.: Clin. Exp. Res. 19 (1995) 226-232
32. Hirsch E., Danober L., Simler S., Pereira de Vasconcelos A., Maton B., Nehlig A., Marescaux C., and Vergnes M. The amygdala is critical for seizure propagation from brainstem to forebrain. Neuroscience 77 (1997) 975-984
33. Hu X.J., and Ticku M.K. Functional characterization of a kindling-like model of ethanol withdrawal in cortical cultured neurons after chronic intermittent ethanol exposure. Brain Res. 767 (1997) 228-234
34. Knapp D.J., and Crews F.T. Induction of cyclooxygenase-2 in brain during acute and chronic ethanol treatment and ethanol withdrawal. Alcohol.: Clin. Exp. Res. 23 (1999) 633-643
35. Koob G.F., Roberts A.J., Schulteis G., Parsons L.H., Heyser C.J., Hyytia P., Merlo-Pich E., and Weiss F. Neurocircuitry targets in ethanol reward and dependence. Alcohol.: Clin. Exp. Res. 22 1 (1998) 3-9
36. LeDoux J.E. Emotion circuits in the brain. Annu. Rev. Neurosci. 23 (2000) 155-184
37. Lowry C.A., Rodda J.E., Lightman S.L., and Ingram C.D. Corticotropin-releasing factor increases in vitro firing rates of serotonergic neurons in the rat dorsal raphe nucleus: evidence for activation of a topographically organized mesolimbocortical serotonergic system. J. Neurosci. 20 (2000) 7728-7736
38. Majchrowicz E. Induction of physical dependence upon ethanol and the associated behavioral changes in rats. Psychopharmacologia 43 (1975) 245-254
39. McCown T.J., Duncan G.E., Johnson K.B., and Breese G.R. Metabolic and functional mapping of the neural network subserving inferior collicular seizure generalization. Brain Res. 701 1-2 (1995) 117-128
40. Millan M.H., Patel S., Mello L.M., and Meldrum B.S. Focal injection of 2-amino-7-phosphonoheptanoic acid into prepiriform cortex protects against pilocarpine-induced limbic seizures in rats. Neurosci. Lett. 70 (1986) 69-74
41. Morales M., Criado J.R., Sanna P.P., Henriksen S.J., and Bloom F.E. Acute ethanol induces c-fos immunoreactivity in GABAergic neurons of the central nucleus of the amygdale. Brain Res. 798 (1998) 333-336
42. Naritoku D.K., Mecozzi L.B., Aiello M.T., and Faingold C.L. Repetition of audiogenic seizures in genetically epilepsy-prone rats induces cortical epileptiform activity and additional seizure behaviors. Exp. Neurol. 115 3 (1992) 317-324
43. N'Gouemo P., Caspary D.M., and Faingold C.L. Decreased GABA effectiveness in the inferior colliculus neurons during ethanol withdrawal in rats susceptible to audiogenic seizures. Brain Res. 724 (1996) 200-204
44. Nie Z., Schweitzer P., Roberts A.J., Madamba S.G., Moore S.D., and Siggins G.R. Ethanol augments GABAergic transmission in the central amygdala via CRF1 receptors. Science 303 (2004) 1512-1514
45. Nishio M., and Narahashi T. Ethanol enhancement of GABA-activated chloride current in rat dorsal root ganglion neurons. Brain Res. 518 (1990) 283-286
46. A receptors in brains of rats treated with chronic intermittent ethanol. Neurochem. Res. 30 (2005) 1579-1588
47. Overstreet D.H., Knapp D.J., Angel R.A., Navarro M., and Breese G.R. Reduction in repeated ethanol-withdrawal-induced anxiety-like behavior by site-selective injections of 5-HT1A and 5-HT2C ligands. Psychopharmacology (Berlin) 187 1 (2006) 1-12
48. Paxinos G., and Watson C. The Rat Brain in Stereotaxic Coordinates (1998), Academic Press, Orlando
49. Peoples R.W., and Weight F.F. Cutoff in potency implicates alcohol inhibition of N-methyl-d-aspartate receptors in alcohol intoxication. Proc. Natl. Acad. Sci. U. S. A. 92 (1995) 2825-2829
50. Pich E.M., Lorang M., Yeganeh M., Rodriguez de Fonseca F., Raber J., Koob G.F., and Weiss F. Increase of extracellular corticotropin-releasing factor-like immunoreactivity levels in the amygdala of awake rats during restraint stress and ethanol withdrawal as measured by microdialysis. J. Neurosci. 15 (1995) 5439-5447
51. Pieninkeroinen I.P., Telakivi T.M., and Hillbom M.E. Outcome in subjects with alcohol-provoked seizures. Alcohol.: Clin. Exp. Res. 16 (1992) 955-959
52. Rainnie D.G. Serotonergic modulation of neurotransmission in the rat basolateral amygdala. J. Neurophysiol. 82 (1999) 69-85
53. Raisinghani M., and Faingold C.L. Pontine reticular formation neurons are implicated in the neuronal network for generalized clonic seizures which is intensified by audiogenic kindling. Brain Res. 1064 1-2 (2005) 90-97
54. Rassnick S., Heinrichs S.C., Britton K.T., and Koob G.F. Microinjection of a corticotropin-releasing factor antagonist into the central nucleus of the amygdala reverses anxiogenic-like effects of ethanol withdrawal. Brain Res. 605 (1993) 25-32
55. Riaz A., and Faingold C.L. Seizures during ethanol withdrawal are blocked by focal microinjection of excitant amino acid antagonists into the inferior colliculus and pontine reticular formation. Alcohol.: Clin. Exp. Res. 18 (1994) 1456-1462
56. Ripley T.L., Borlikova G., Lyons S., and Stephens D.N. Selective deficits in appetitive conditioning as a consequence of ethanol withdrawal. Eur. J. Neurosci. 19 (2004) 415-425
57. Roberto M., Madamba S.G., Moore S.D., Tallent M.K., and Siggins G.R. Ethanol increases GABAergic transmission at both pre- and postsynaptic sites in rat central amygdala neurons. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 2053-2058
58. Roberto M., Schweitzer P., Madamba S.G., Stouffer D.G., Parsons L.H., and Siggins G.R. Acute and chronic ethanol alter glutamatergic transmission in rat central amygdala: an in vitro and in vivo analysis. J. Neurosci. 24 (2004) 1594-1603
59. Ryabinin A.E., Criado J.R., Henriksen S.J., Bloom F.E., and Wilson M.C. Differential sensitivity of c-Fos expression in hippocampus and other brain regions to moderate and low doses of alcohol. Mol. Psychiatry 2 (1997) 32-43
60. Siggins G.R., Martin G., Roberto M., Nie Z., Madamba S., and De Lecea L. Glutamatergic transmission in opiate and alcohol dependence. Ann. N. Y. Acad. Sci. 1003 (2003) 196-211
61. Stutzmann G.E., and LeDoux J.E. GABAergic antagonists block the inhibitory effects of serotonin in the lateral amygdala: a mechanism for modulation of sensory inputs related to fear conditioning. J. Neurosci. 19 (1999) RC8
62. Thomas M.P., Monaghan D.T., and Morrisett R.A. Evidence for a causative role of N-methyl-d-aspartate receptors in an in vitro model of alcohol withdrawal hyperexcitability. J. Pharmacol. Exp. Ther. 287 (1998) 87-97
63. Veatch L.M., and Gonzalez L.P. Repeated ethanol withdrawal produces site-dependent increases in EEG spiking. Alcohol.: Clin. Exp. Res. 20 2 (1996) 262-267
64. Victor M. Alcohol withdrawal seizures: an overview. In: Porter R.J., Mattson R.H., Cramer J.A., and Diamond I. (Eds). Alcohol and Seizures: Basic Mechanisms and Clinical Concepts (1990), F.A. Davis Company, Philadelphia 148-161
65. A-mediated synaptic current by ethanol in hippocampal CA1 neurons: possible role of protein kinase C. J. Pharmacol. Exp. Ther. 268 (1994) 1388-1395
66. Yang L., Long C., and Faingold C.L. Neurons in the deep layers of superior colliculus are a requisite component of the neuronal network for seizures during ethanol withdrawal. Brain Res. 920 (2001) 134-141
67. Yang L., Long C., Evans M.S., and Faingold C. Ethanol withdrawal results in aberrant membrane properties and synaptic responses in periaqueductal gray neurons associated with seizure susceptibility. Brain Res. 957 (2002) 99-108
68. Yang L., Long C., Randall M.E., and Faingold C.L. Neurons in the periaqueductal gray are critically involved in the neuronal network for audiogenic seizures during ethanol withdrawal. Neuropharmacology 44 (2003) 275-281