Functional characterization of a kindling-like model of ethanol withdrawal in cortical cultured neurons after chronic intermittent ethanol exposure

Brain Research

Volumn 767, Issue 2, 1997, Pages 228-234

  Hu, Xian Jue ^a   Ticku, Maharaj K ^a  

^a University of Texas Health Science Center   (United States)

Author keywords

36Cl influx; Chronic intermittent ethanol (CIE); Intracellular free calcium; Kindling; MK 801; Ro15 4513

Indexed keywords

ALCOHOL;

ALCOHOLISM; ANIMAL CELL; ARTICLE; BINDING SITE; BRAIN CORTEX; CALCIUM CELL LEVEL; CENTRAL NERVOUS SYSTEM; DRUG DEPENDENCE; DRUG RECEPTOR BINDING; ELECTROPHYSIOLOGY; GENE EXPRESSION REGULATION; MOUSE; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; SEIZURE; WITHDRAWAL SYNDROME;

ANIMALS; CELLS, CULTURED; CEREBRAL CORTEX; DIAZEPAM; DRUG ADMINISTRATION SCHEDULE; ETHANOL; FEMALE; GABA MODULATORS; KINDLING, NEUROLOGIC; MALE; MICE; MICE, INBRED C57BL; MODELS, NEUROLOGICAL; NEURONS; PENTYLENETETRAZOLE; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 0030865888     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)00581-7     Document Type: Article

References (36)

1. Ballenger J.C., Post R.M. Kindling as a model for alcohol withdrawal syndromes. Br. J. Psychiatry. 133:1978;1-13.
2. Becker H.C., Hale R.L. Repeated episodes of ethanol withdrawal potentiate the severity of subsequent withdrawal seizures: an animal model of alcohol withdrawal 'kindling'. Alcohol. Clin. Exp. Res. 17:1996;221-228.
3. Branchey M., Rauscher G., Kissin B. Modification in the response to alcohol following the establishment of physical dependence. Psychopharmacologia. 22:1971;314-322.
4. A receptor subunits mRNAs: relationship to genetic differences in ethanol withdrawal seizure severity. J. Neurochem. 57:1991;1452-1455.
5. Corda M.G., Giorgi O., Longoni B., Orlandi M., Biggio G. Decrease in the function of the GABA-coupled chloride channel produced by repeated administration of pentylenetetrazol to rats. J. Neurochem. 55:1990;1216-1221.
6. Davies D.L., Shepherd M., Myers E. The two years prognosis of fifty alcohol addicts after treatment in hospital. Q. J. Study Alcohol. 17:1956;485-502.
7. Diaz-Granados J.L., Reich R.R., Fernandes K.G., Becker H.C. Repeated episodes of ethanol withdrawal lower (PTZ) seizure threshold dose in mice. Soc. Neurosci. Abstr. 21:1995;665.20.
8. Follesa P., Ticku M.K. Chronic ethanol treatment differentially regulates NMDA receptor subunit mRNA expression in rat brain. Mol. Brain Res. 29:1995;99-106.
9. Follesa P., Ticku M.K. Chronic ethanol-mediated up-regulation of the NMDA receptor polypeptide subunits in mouse cortical neurons in culture. J. Biol. Chem. 271:1996;13297-13299.
10. Goldstein D.B. Rates of onset and decay of physical dependence in mice. J. Pharmacol. Exp. Ther. 190:1974;377-383.
11. Grant K.A., Valverius P., Hudspith M., Tabakoff B. Ethanol withdrawal seizures and the NMDA receptor complex. Eur. J. Pharmacol. 176:1990;289-296.
12. 2+ indicators with greatly improved fluorescence properties. J. Biol. Chem. 260:1985;3440-3450.
13. A-benzodiazepine receptor ionophore complex in primary cultures of cortical neurons. Dev. Brain Res. 80:1994;137-140.
14. Hu X.-J., Ticku M.K. Chronic ethanol treatment upregulates the NMDA receptor function and binding in mammalian cortical neurons. Mol. Brain Res. 30:1995;347-356.
15. Hu X.-J., Follesa P., Ticku M.K. Chronic ethanol treatment selectively upregulated the NMDA receptor gene expression. Mol. Brain Res. 36:1996;211-218.
16. Hunt W.A. The effect of ethanol on GABAergic transmission. Neurosci. Biobehav. Rev. 7:1983;87-95.
17. Hunter B.E., Walker D.W., Riley J.N. Dissociation between physical dependence and volitional ethanol consumption: role of multiple withdrawal episodes. Pharmacol. Biochem. Behav. 2:1974;523-529.
18. A receptor-mediated inhibition in rat hippocampus after chronic intermittent ethanol treatment. Brain Res. 709:1996;221-228.
19. A receptors in hippocampus of rats treated with chronic intermittent ethanol. Soc. Neurosci. Abstr. 20:1996;814.1.
20. Kokka N., Sapp D.W., Taylor A.M., Olsen R.W. The kindling model of alcohol dependence: similar persistent reduction in animals receiving chronic ethanol or chronic pentylenetetrazol. Alcohol. Clin. Exp. Res. 17:1993;525-531.
21. Little H.J., Nutt D.J., Taylor S.C. Acute and chronic effects of benzodiazepine receptor ligand FG-7142: proconvulsant properties and kindling. Br. J. Pharmacol. 83:1984;951-958.
22. Mason C.R., Cooper R.M. A permanent change in convulsive threshold in normal and brain-damaged rats with small doses of pentylenetetrazol. Epilepsia. 13:1972;663-674.
23. A receptor gene expression. Mol. Pharmacol. 42:1992;415-422.
24. 3H]Ro15-4513 in rat brain. Eur. J. Pharmacol. 153:1988;141-145.
25. A receptor α-subunits reveal that chronic alcohol treatment down-regulates α-subunit expression in rat brain regions. J. Neurochem. 61:1993;1620-1625.
26. A receptor α-subunit mRNAs in the rat cerebral cortex. Mol. Pharmacol. 39:1991;157-163.
27. Morin A.M., Watson A.L., Wasterlain C. Kindling of seizures with norharman, a β-carboline ligand of benzodiazepine receptors. Eur. J. Pharmacol. 88:1983;131-134.
28. 6 subunit mRNA levels in rat cerebellum. J. Mol. Cell. Neurosci. 3:1992;251-258.
29. Nielsen R.E., Jepsen S.A., Nielsen M., Braestrup C. Discriminative stimulus properties of methyl 6,7-dimethoxy-4-ethyl-β-carboline-3-carboxylate (DMCM), an inverse agonist at benzodiazepine receptors. Life Sci. 36:1985;15-23.
30. Nutt D.J., Glue P. Neuropharmacological and clinical aspects of alcohol withdrawal. Ann. Med. 22:1990;275-281.
31. Ollat H., Parvez H., Parvez S. Alcohol and central neurotransmission. Neurochem. Int. 13:1988;275-300.
32. Ramanjaneyulu R., Ticku M.K. Interaction of pentamethylenetetrazol and tetrazole analogues with the picrotoxin site of the benzodiazepine-GABA receptor-ionophore complex. Eur. J. Pharmacol. 98:1984;337-345.
33. Redinbaugh M.D., Turley R.B. Adaption of the bicinchoninic acid protein assay for use with microliter plates and sucrose gradient fractions. Anal. Biochem. 153:1986;267-271.
34. A and NMDA receptor function in rat brain. Alcohol. Clin. Exp. Res. 17:1993;115-123.
35. Ulrichsen J., Clemmesen L., Barry D., Hemmingsen R. The GABA/benzodiazepine receptor chloride channel complex during repeated episodes of physical ethanol dependence in rat. Psychopharmacology. 96:1988;227-231.
36. 4 subunit. FEBS Lett. 289:1991;227-240.