The fission yeast DASH complex is essential for satisfying the spindle assembly checkpoint induced by defects in the inner-kinetochore proteins

Genes to Cells

Volumn 12, Issue 3, 2007, Pages 311-328

  Kobayashi, Yasuyo ^a   Saitoh, Shigeaki ^a   Ogiyama, Yuki ^a   Soejima, Saeko ^a   Takahashi, Kohta ^a  

^a KURUME UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL PROTEIN; MICROTUBULE PROTEIN; PROTEIN DAM1; PROTEIN DASH; PROTEIN DIS1; PROTEIN HOS2; PROTEIN TOG; PROTEIN XMAP215; UNCLASSIFIED DRUG;

ANEUPLOIDY; ARTICLE; CELL VIABILITY; CELLULAR DISTRIBUTION; CENTROMERE; CHROMOSOMAL INSTABILITY; CHROMOSOME SEGREGATION; FUNGUS ISOLATION; GENE DELETION; GENE INTERACTION; GENE MUTATION; GENE OVEREXPRESSION; METAPHASE; MICROTUBULE ASSEMBLY; MITOSIS; MITOSIS SPINDLE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMETAPHASE; PROTEIN BINDING; PROTEIN FUNCTION; TEMPERATURE SENSITIVE MUTANT;

BASE SEQUENCE; CELL CYCLE PROTEINS; CENTROMERE; DNA, FUNGAL; GENES, FUNGAL; KINETOCHORES; METAPHASE; MITOSIS; MITOTIC SPINDLE APPARATUS; MUTATION; NUCLEAR PROTEINS; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE PROTEINS;

SCHIZOSACCHAROMYCETACEAE;

EID: 33847636159     PISSN: 13569597     EISSN: 13652443     Source Type: Journal    
DOI: 10.1111/j.1365-2443.2007.01053.x     Document Type: Article

References (56)

1. Allmang, C., Petfalski, E., Podtelejnikov, A., Mann, M., Tollervey, D. & Mitchell, P. (1999) The yeast exosome and human PM-Scl are related complexes of 3′→ 5′ exonucleases. Genes Dev. 13, 2148-2158.
2. Aoki, K., Nakaseko, Y., Kinoshita, K., Goshima, G. & Yanagida, M. (2006) CDC2 phosphorylation of the fission yeast dis1 ensures accurate chromosome segregation. Curr. Biol. 16, 1627-1635.
3. Bahler, J., Wu, J.Q., Longtine, M.S., Shah, N.G., McKenzie, A. 3rd, Steever, A.B., Wach, A., Philippsen, P. & Pringle, J.R. (1998) Heterologous modules for efficient and versatile PCR-based gene targeting in Schizosaccharomyces pombe. Yeast 14, 943-951.
4. Bernard, P., Hardwick, K. & Javerzat, J.P. (1998) Fission yeast bubl is a mitotic centromere protein essential for the spindle checkpoint and the preservation of correct ploidy through mitosis. J. Cell. Biol. 143, 1775-1787.
5. Bernard, P., Maure, J.F., Partridge, J.F., Genier, S., Javerzat, J.P. & Allshire, R.C. (2001) Requirement of heterochromatin for cohesion at centromeres. Science 294, 2539-2542.
6. Brito, D.A. & Rieder, C.L. (2006) Mitotic checkpoint slippage in humans occurs via cyclin B destruction in the presence of an active checkpoint. Curr. Biol. 16, 1194-1200.
7. Cahill, D.P., Lengauer, C., Yu, J., Riggins, G.J., Willson, J.K., Markowitz, S.D., Kinzler, K.W. & Vogelstein, B. (1998) Mutations of mitotic checkpoint genes in human cancers. Nature 392, 300-303.
8. Cheeseman, I.M., Anderson, S., Jwa, M., Green, E.M., Kang, J., Yates, J.R. 3rd, Chan, C.S., Drubin, D.G. & Barnes, G. (2002) Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p. Cell 111, 163-172.
9. Cheeseman, I.M., Enquist-Newman, M., Muller-Reichert, T., Drubin, D.G. & Barnes, G. (2001) Mitotic spindle integrity and kinetochore function linked by the Duo1p/Dam1p complex. J. Cell Biol. 152, 197-212.
10. Cleveland, D.W., Mao, Y. & Sullivan, K.F. (2003) Centromeres and kinetochores: From epigenetics to mitotic checkpoint signaling. Cell 112, 407-421.
11. Decottignies, A., Zarzov, P. & Nurse, P. (2001) In vivo localisation of fission yeast cyclin-dependent kinase cdc2p and cyclin B cdc13p during mitosis and meiosis. J. Cell Sci. 114, 2627-2640.
12. Ekwall, K., Javerzat, J.P., Lorentz, A., Schmidt, H., Cranston, G. & Allshire, R. (1995) The chromodomain protein Swi6: A key component at fission yeast centromeres. Science 269, 1429-1431.
13. Garcia, M.A., Koonrugsa, N. & Toda, T. (2002) Two kinesin-like Kin I family proteins in fission yeast regulate the establishment of metaphase and the onset of anaphase A. Curr. Biol. 12, 610-621.
14. Garcia, M.A., Vardy, L., Koonrugsa, N. & Toda, T. (2001) Fission yeast ch-TOG/XMAP215 homologue Alp14 connects mitotic spindles with the kinetochore and is a component of the Mad2-dependent spindle checkpoint. EMBO J. 20, 3389-3401.
15. Goshima, G., Saitoh, S. & Yanagida, M. (1999) Proper metaphase spindle length is determined by centromere proteins Mis12 and Mis6 required for faithful chromosome segregation. Genes Dev. 13, 1664-1677.
16. Hagan, I. & Yanagida, M. (1990) Novel potential mitotic motor protein encoded by the fission yeast cut7 + gene. Nature 347, 563-566.
17. Hanisch, A., Sillje, H.H. & Nigg, E.A. (2006) Timely anaphase onset requires a novel spindle and kinetochore complex comprising Ska1 and Ska2. EMBO J. 25, 5504-5515.
18. Hayashi, T., Fujita, Y., Iwasaki, O., Adachi, Y., Takahashi, K. & Yanagida, M. (2004) Mis16 and Mis18 are required for CENP-A loading and histone deacetylation at centromeres. Cell 118, 715-729.
19. Hentges, P., Van Driessche, B., Tafforeau, L., Vandenhaute, J. & Carr, A.M. (2005) Three novel antibiotic marker cassettes for gene disruption and marker switching in Schizosaccharomyces pombe. Yeast 22, 1013-1019.
20. Hiraoka, Y., Toda, T. & Yanagida, M. (1984) The NDA3 gene of fission yeast encodes beta-tubulin: A cold-sensitive nda3 mutation reversibly blocks spindle formation and chromosome movement in mitosis. Cell 39, 349-358.
21. Ikui, A.E., Furuya, K., Yanagida, M. & Matsumoto, T. (2002) Control of localization of a spindle checkpoint protein, Mad2, in fission yeast. J. Cell Sci. 115, 1603-1610.
22. Janke, C., Ortiz, J., Tanaka, T.U., Lechner, J. & Schiebel, E. (2002) Four new subunits of the Dam1-Duo1 complex reveal novel functions in sister kinetochore biorientation. EMBO J. 21, 181-193.
23. Jones, M.H., He, X., Giddings, T.H. & Winey, M. (2001) Yeast Dam1p has a role at the kinetochore in assembly of the mitotic spindle. Proc. Natl. Acad. Sci. USA 98, 13675-13680.
24. Kim, S.H., Lin, D.P., Matsumoto, S., Kitazono, A. & Matsumoto, T. (1998) Fission yeast Slp1: An effector of the Mad2-dependent spindle checkpoint. Science 279, 1045-1047.
25. + gene encodes a 110-kDa essential protein implicated in mitotic control. Mol. Cell. Biol. 11, 5839-5847.
26. Krawchuk, M.D. & Wahls, W.P. (1999) High-efficiency gene targeting in Schizosaccharomyces pombe using a modular, PCR-based approach with long tracts of flanking homology. Yeast 15, 1419-1427.
27. Li, Y., Bachant, J., Alcasabas, A.A., Wang, Y., Qin, J. & Elledge, S.J. (2002) The mitotic spindle is required for loading of the DASH complex onto the kinetochore. Genes Dev. 16, 183-197.
28. Liu, X., McLeod, I., Anderson, S., Yates, J.R. & He, X. (2005) Molecular analysis of kinetochore architecture in fission yeast. EMBO J. 24, 2919-2930.
29. Miranda, J.J., De Wulf, P., Sorger, P.K. & Harrison, S.C. (2005) The yeast DASH complex forms closed rings on microtubules. Nat. Struct. Mol. Biol. 12, 138-143.
30. Moreno, S., Klar, A. & Nurse, P. (1991) Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. Methods Enzymol. 194, 795-823.
31. Nabeshima, K., Kurooka, H., Takeuchi, M., Kinoshita, K., Nakaseko, Y. & Yanagida, M. (1995) p93 dis1, which is required for sister chromatid separation, is a novel microtubule and spindle pole body-associating protein phosphorylated at the Cdc2 target sites. Genes Dev. 9, 1572-1585.
32. Nabeshima, K., Nakagawa, T., Straight, A.F., Murray, A., Chikashige, Y., Yamashita, Y.M., Hiraoka, Y. & Yanagida, M. (1998) Dynamics of centromeres during metaphase-anaphase transition in fission yeast: Dis1 is implicated in force balance in metaphase bipolar spindle. Mol. Biol. Cell 9, 3211-3225.
33. Nabetani, A., Koujin, T., Tsutsumi, C., Haraguchi, T. & Hiraoka, Y. (2001) A conserved protein, Nuf2, is implicated in connecting the centromere to the spindle during chromosome segregation: A link between the kinetochore function and the spindle checkpoint. Chromosoma 110, 322-334.
34. Nakamichi, N., Yamamoto, E., Yamada, H., Aiba, H. & Mizuno, T. (2000) Identification and characterization of a novel gene, hos2+, the function of which is necessary for growth under high osmotic stress in fission yeast. Biosci. Biotechnol. Biochem. 64, 2493-2496.
35. Nakaseko, Y., Goshima, G., Morishita, J. & Yanagida, M. (2001) M phase-specific kinetochore proteins in fission yeast: microtubule-associating Dis1 and Mtc1 display rapid separation and segregation during anaphase. Curr. Biol. 11, 537-549.
36. Dis1: Regions implicated in regulated localization and microtubule interaction. Genes Cells 1, 633-644.
37. Obuse, C., Iwasaki, O., Kiyomitsu, T., Goshima, G., Toyoda, Y. & Yanagida, M. (2004) A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1. Nat. Cell Biol. 6, 1135-1141.
38. Ohkura, H., Adachi, Y., Kinoshita, N., Niwa, O., Toda, T. & Yanagida, M. (1988) Cold-sensitive and caffeine-supersensitive mutants of the Schizosaccharomyces pombe dis genes implicated in sister chromatid separation during mitosis. EMBO J. 7, 1465-1473.
39. + gene required for chromosome disjoining encodes one of two putative type 1 protein phosphatases. Cell 57, 997-1007.
40. Partridge, J.F., Borgstrom, B. & Allshire, R.C. (2000) Distinct protein interaction domains and protein spreading in a complex centromere. Genes Dev. 14, 783-791.
41. Pidoux, A.L., Richardson, W. & Allshire, R.C. (2003) Sim4: A novel fission yeast kinetochore protein required for centromeric silencing and chromosome segregation. J. Cell Biol. 161, 295-307.
42. Rieder, C.L. & Maiato, H. (2004) Stuck in division or passing through: What happens when cells cannot satisfy the spindle assembly checkpoint. Dev. Cell 7, 637-651.
43. Saitoh, S., Ishii, K., Kobayashi, Y. & Takahashi, K. (2005) Spindle checkpoint signaling requires the mis6 kinetochore subcomplex, which interacts with mad2 and mitotic spindles. Mol. Biol. Cell 16, 3666-3677.
44. Saitoh, S., Takahashi, K. & Yanagida, M. (1997) Mis6, a fission yeast inner centromere protein, acts during G1/S and forms specialized chromatin required for equal segregation. Cell 90, 131-143.
45. Sanchez-Perez, I., Renwick, S.J., Crawley, K., Karig, I., Buck, V., Meadows, J.C., Franco-Sanchez, A., Fleig, U., Toda, T. & Millar, J.B. (2005) The DASH complex and Klp5/Klp6 kinesin coordinate bipolar chromosome attachment in fission yeast. EMBO J. 24, 2931-2943.
46. Shang, C., Hazbun, T.R., Cheeseman, I.M., Aranda, J., Fields, S., Drubin, D.G. & Barnes, G. (2003) Kinetochore protein interactions and their regulation by the Aurora kinase Ipl1p. Mol. Biol. Cell 14, 3342-3355.
47. Takahashi, K., Chen, E.S. & Yanagida, M. (2000) Requirement of Mis6 centromere connector for localizing a CENP-A-like protein in fission yeast. Science 288, 2215-2219.
48. Takahashi, K., Murakami, S., Chikashige, Y., Funabiki, H., Niwa, O. & Yanagida, M. (1992) A low copy number central sequence with strict symmetry and unusual chromatin structure in fission yeast centromere. Mol. Biol. Cell 3, 819-835.
49. Takahashi, K., Yamada, H. & Yanagida, M. (1994) Fission yeast minichromosome loss mutants mis cause lethal aneuploidy and replication abnormality. Mol. Biol. Cell 5, 1145-1158.
50. Tanaka, T.U. (2005) Chromosome bi-orientation on the mitotic spindle. Philos. Trans. R. Soc. Lond. B. Biol. Sci. 360, 581-589.
51. Toyoda, Y., Furuya, K., Goshima, G., Nagao, K., Takahashi, K. & Yanagida, M. (2002) Requirement of chromatid cohesion proteins rad21/ scc1 and mis4/scc2 for normal spindle-kinetochore interaction in fission yeast. Curr. Biol. 12, 347-358.
52. Vanoosthuyse, V., Valsdottir, R., Javerzat, J.P. & Hardwick, K.G. (2004) Kinetochore targeting of fission yeast Mad and Bub proteins is essential for spindle checkpoint function but not for all chromosome segregation roles of Bub1p. Mol. Cell Biol. 24, 9786-9801.
53. Westermann, S., Avila-Sakar, A., Wang, H.W., Niederstrasser, H., Wong, J., Drubin, D.G., Nogales, E. & Barnes, G. (2005) Formation of a dynamic kinetochore-microtubule interface through assembly of the Dam1 ring complex. Mol. Cell 17, 277-290.
54. Westermann, S., Wang, H.W., Avila-Sakar, A., Drubin, D.G., Nogales, E. & Barnes, G. (2006) The Dam1 kinetochore ring complex moves processively on depolymerizing microtubule ends. Nature 440, 565-569.
55. Yamada, H., Kumada, K. & Yanagida, M. (1997) Distinct subunit functions and cell cycle regulated phosphorylation of 20S APC/cyclosome required for anaphase in fission yeast. J. Cell Sci. 110 (15), 1793-1804.
56. Yamashita, Y.M., Nakaseko, Y., Kumada, K., Nakagawa, T. & Yanagida, M. (1999) Fission yeast APC/cyclosome subunits, Cut20/Apc4 and Cut23/ Apc8, in regulating metaphase-anaphase progression and cellular stress responses. Genes Cells 4, 445-463.