CXXC finger protein 1 is required for normal proliferation and differentiation of the PLB-985 myeloid cell line

DNA and Cell Biology

Volumn 26, Issue 2, 2007, Pages 80-90

  Young, Suzanne R L ^a   Skalnik, David G ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSINE; DNA BINDING PROTEIN; DNA METHYLTRANSFERASE 1; HISTONE METHYLTRANSFERASE; PROTEIN CFP1; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ARTICLE; BONE MARROW CELL; BONE MARROW CULTURE; CELL CLONE; CELL COUNT; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE REGULATION; CELL CYCLE S PHASE; CELL DIFFERENTIATION; CELL NUCLEUS; CELL PROLIFERATION; CELL STRAIN; CELL STRAIN PLB 985; CELL SURVIVAL; CONTROLLED STUDY; CPG ISLAND; CYTOARCHITECTURE; DNA METHYLATION; GENETIC TRANSFECTION; GRANULOCYTE; HEMATOPOIESIS; HUMAN; HUMAN CELL; MACROPHAGE; MOLECULAR CLONING; MONOCYTE; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; RESPIRATORY BURST; RNA INTERFERENCE;

CELL CYCLE; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CYSTEINE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; DNA-BINDING PROTEINS; HUMANS; MONOCYTES; MYELOID CELLS;

DANIO RERIO; MAMMALIA;

EID: 33847611155     PISSN: 10445498     EISSN: None     Source Type: Journal    
DOI: 10.1089/dna.2006.0535     Document Type: Article

References (59)

1. AASLAND, R., GIBSON, T.J., and STEWART, F. (1995). The PHD finger: Implications for chromatin-mediated transcriptional regulation. Trends Biochem. Sci. 20, 56-59.
2. ADAMSON, A.L., and SHEARN, A. (1996). Molecular genetic analysis of Drosophila ash2, a member of the trithorax group required for imaginal disc pattern formation. Genetics 144, 621-633.
3. ARANY, Z., NEWSOME, D., OLREAD, E., LIVINGSTON, D.M., and ECKNER, R. (1995). A family of transcriptional adaptor proteins targeted by the E1A oncoprotein. Nature 374, 81-84.
4. BALAGHI, M., and WAGNER, C. (1993). DNA methylation in folate deficiency: Use of CpG methylase. Biochem. Biophys. Res. Commun. 193, 1184-1190.
5. BESTOR, T.H., and VERDINE, G.L. (1994). DNA methyltransferases. Curr. Opin. Cell Biol. 6, 380-389.
6. BINISZKIEWICZ, D., GRIBNAU, J., RAMSAHOYE, B., GAUDET, F., EGGAN, K., HUMPHERYS, D., MASTRANGELO, M.-A., JUN, Z., WALTER, J., and JAENISCH, R. (2002). Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality. Mol. Cell. Biol. 22, 2124-2135.
7. BRADFORD, M.M. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
8. CARLONE, D.L., and SKALNIK, D.G. (2001). CpG binding protein is crucial for early embryonic development. Mol. Cell. Biol. 21, 7601-7606.
9. CARLONE, D.L., HART, S.R.L., LADD, P.D., and SKALNIK, D.G. (2002). Cloning and characterization of the gene encoding the mouse homologue of CpG binding protein. Gene 295, 71-77.
10. CARLONE, D.L., LEE, J.-H., YOUNG, S.R.L., DOBROTA, E., BUTLER, J.S., RUIZ, J., and SKALNIK, D.G. (2005). Reduced genomic cytosine methylation and defective cellular differentiation in embryonic stem cells lacking CpG binding protein. Mol. Cell. Biol. 25, 4881-4891.
11. CHAN, M.F., VAN AMERONGEN, R., JIJJAR, T., CUPPEN, E., JONES, P.A., and LAIRD, P.W. (2001). Reduced rates of gene loss, gene silencing, and gene mutation in Dnmt1-deficient embryonic stem cells. Mol. Biol. Cell. 21, 7587-7600.
12. COLLINS, S.J., GALLO, R.C., and GALLAGHER, R.E. (1977). Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture. Nature 270, 347-348.
13. CROSS, S.H., MEEHAN, R.R., NAN, X., and BIRD, A. (1997). A component of the transcriptional repressor MeCP1 shares a motif with DNA methyltransferase and HRX proteins. Nat. Genet. 16, 256-259.
14. DETICH, N., RAMCHANDANI, S., and SZYF, M. (2001). A conserved 3′-untranslated element mediates growth regulation of DNA methyltransferase 1 and inhibits its transforming activity. J. Biol. Chem. 276, 24881-24890.
15. DODGE, J.E., KANG, Y.K., BEPPU, H., LEI, H., and LI, E. (2004). Histone H3-K9 methyltansferase ESET is essential for early development. Mol. Cell. Biol. 24, 2478-2486.
16. DOMER, P.H., FAKHARZADEH, S.S., CHEN, C.S., JOCKEL, J., JOHANSEN, L., SILVERMAN, G.A., KERSEY, J.H., and KORSMEYER, S.J. (1993). Acute mixed-lineage leukemia t(4;11)(q21;q23) generates an MLL-AF4 fusion product. Proc. Natl. Acad. Sci. USA 90, 7884-7888.
17. ERNST, P., FISHER, J.K., AVERY, W., WADE, S., FOY, D., and KORSMEYER, S.J. (2004). Definitive hematopoiesis requires the mixed-lineage leukemia gene. Dev. Cell 6, 437-443.
18. FITZGERALD, K.T., and DIAZ, M.O. (1999). MLL2: A new mammalian member of the trx/MLL family of genes. Genomics 59, 187-192.
19. FU, Q., JILKA, R.L., MANOLAGAS, S.C., and O'BRIEN, C.A. (2002). Parathyroid hormone stimulates receptor activator of NF B ligand and inhibits osteoprotegerin expression via protein kinase A activation of cAMP-response element-binding protein. J. Biol. Chem. 277, 48868-48875.
20. GIBBONS, R.J., BACHOO, S., PICKETTS, D.J., AFTIMOS, S., ASENBAUER, B., BERGOFFEN, J., BERRY, S.A., DAHL, N., FRYER, A., KEPPLER, K., et al. (1997). Mutations in transcriptional regulatory of ATRX establish the functional significance of a PHD-like domain. Nat. Genet. 17, 146-148.
21. GU, Y., NAKAMURA, T., ALDER, H., PRASAD, R., CANAANI, O., CIMINO, G., CROCE, C.M., and CANAANI, E. (1992). The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene. Cell 71, 701-708.
22. HARPOLD, M.M., EVANS, R.M., SALDITT-GEORGIEFF, M., and DARNELL, J.E. (1979). Production of mRNA in Chinese hamster cells: Relationship of the rate of synthesis to the cytoplasmic concentrations of nine specific mRNA sequences. Cell 17, 1025-1035.
23. HENDRICH, B., and BIRD, A. (1998). Identification and characterization of a family of mammalian methyl-CpG binding proteins. Mol. Cell. Biol. 18, 6538-6547.
24. HONG, L., OH, S.P., OKANO, M., JUTTERMANN, R., GROSS, K.A., JAENISCH, R., and LI, E. (1996). De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells. Development 122, 3195-3205.
25. HUGHES, C.M., ROZENBLATT-ROSEN, O., MILNE, T.A., COPELAND, T.D., LEVINE, S.S., LEE, J.C., HAYES, D.N., SHANMUGAM, K.S., BHATTACHARJEE, A., BIONDI, C.A., et al. (2004). Menin associates with a trithorax family histone methyltransferase complex and with the Hoxc8 locus. Mol. Cell 13, 587-597.
26. JACKSON, M., KRASSOWSKA, A., GILBERT, N., CHEVASSUT, T., FORRESTER, L., ANSELL, J., and RAMSAHOYE, B. (2004). Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells. Mol. Cell. Biol. 24, 8862-8871.
27. LANGST, G., and BECKER, P.B. (2001). Nucleosome mobilization and positioning by ISWI-containing chromatin-remodeling factors. J. Cell Sci. 114, 2561-2568.
28. LEE, J.-H., and SKALNIK, D.G. (2002). CpG binding protein is a nuclear matrix- and euchromatin-associated protein localized to nuclear speckles containing human trithorax: Identification of nuclear matrix targeting signals. J. Biol. Chem. 277, 42259-42267.
29. LEE, J.-H., and SKALNIK, D.G. (2005). CpG binding protein (CXXC finger protein 1) is a component of the mammalian Set1 histone H3-Lys4 methyltransferase complex, the analogue of the yeast Set1/COMPASS complex. J. Biol. Chem. 280, 41725-41731.
30. LEE, J.-H., VOO, K.S., and SKALNIK, D.G. (2001). Identification and characterization of the DNA binding domain of CpG-binding protein. J. Biol. Chem. 276, 44669-44676.
31. LEE, J.-H., HART, S.R.L., and SKALNIK, D.G. (2004). Histone deacetylase activity is required for embryonic stem cell differentiation. Genesis 38, 32-38.
32. LI, B., YANG, F.-C., CLAPP, D.W., and CHUN, K.T. (2003). Enforced expression of CUL-4A interferes with granulocytic differentiation and exit from the cell cycle. Blood 101, 1769-1776.
33. LI, E., BESTOR, T.H., and JAENISCH, R. (1992). Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69, 915-926.
34. LI, H., LLIN, S., WANG, W., DUNCAN, E.M., WYSOCKA, J., ALLIS, C.D., and PATEL, D.J. (2006). Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF. Nature 442, 91-95.
35. MA, Q., ALDER, H., NELSON, K.K., CHATTERJEE, D., GU, Y., NAKAMURA, T., CANAANI, E., CROCE, C.M., SIRACUSA, L.D., and BUCHBERG, A.M. (1993). Analysis of the murine ALL-1 gene reveals conserved domains with human ALL-1 and identifies a motif shared with DNA methyltransferases. Proc. Natl. Acad. Sci. USA 90, 6350-6354.
36. MILLER, S.A., DYKES, D.D., and POLESKY, H.F. (1988). A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 16, 1215.
37. MILUTINOVIC, S., ZHUANG, Q., NIVELEAU, A., and SZYF, M. (2003). Epigenomic stress response: Knockdown of DNA methyltransferae 1 triggers an intra-S-phase arrest of DNA replication and induction of stress response genes. J. Biol. Chem. 278, 14985-14995.
38. OKANO, M., BELL, D.W., HABER, D.A., and LI, E. (1999). DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99, 247-257.
39. ONO, R., TAKI, T., TAKETANI, T., TANIWAKI, M., KOBAYASHI, H., and HAYASHI, Y. (2002). LCX, leukemia-associated protein with a CXXC domain, is fused to MLL in acute myeloid leukemia with trilineage dysplasia having t(10;11)(q22;q23). Cancer Res. 62, 4075-4080.
40. PARKOS, C.A., DINAUER, M.C., WALKER, L.E., ALLEN, R.A., JESAITIS, A.J., and ORKIN, S.H. (1988). Primary structure and unique expression of the 22-kilodalton light chain of human neutrophil cytochrome b. Proc. Natl. Acad. Sci. USA 85, 3319-3323.
41. PENA, P.V., DAVRAZOU, F., SHI, X., WALTER, K.L., VERKHUSHA, V.V., GOZANI, O., ZHAO, R., and KUTATE-LADZE, T.G. (2006). Molecular mechanism of histone H3K4me3 recognition by plant homeodomain of ING2. Nature 442, 100-103.
42. PRASAD, R., YANO, T., SORIO, C., NAKAMURA, T., RALLA-PALLI, R., GU, Y., LESHKOWITZ, D., CROCE, C.M., and CANAANI, E. (1995). Domains with transcriptional regulatory activity within the ALL1 and AF4 proteins involved in acute leukemia. Proc. Natl. Acad. Sci. USA 92, 12160-12164.
43. ROVERA, G., SANTOLI, D., and DAMSKY, C. (1979). Human promyelocytic leukemia cells in culture differentiate into macrophage-like cells when treated with a phorbol diester. Proc. Natl. Acad. Sci. USA 76, 2779-2783.
44. RUBART, M., SOONPAA, M.H., NAKAJIMA, H., and FIELD, L.J. (2004). Spontaneous and evoked intracellular calcium transients in donor-derived myocytes following intracardiac myoblast transplantation. J. Clin. Invest. 114, 775-783.
45. SARRAF, S.A., and STANCHEVA, I. (2004). Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly. Mol. Cell 15, 595-605.
46. SEELIG, H.-P., MOOSBRUGGER, I., EHRFELD, H., FINK, T., RENZ, M., and GENTH, E. (1995). The major dermatomyositis-specific Mi-2 autoantigen is a presumed helicase involved in transcripitonal activation. Arthritis Rheum. 38, 1389-1399.
47. SHEN, Q., CHADA, S., WHITNEY, C., and NEWBURGER, P.E. (1994). Regulation of the human cellular glutathione peroxidase gene during in vitro myeloid and monocytic differentiation. Blood 84, 3902-3908.
48. SHI, X., HONG, T., WALTER, K.L., EWALT, M., MICHISHITA, E., HUNG, T., CARNEY, D., PENA, P., LAN, F., KAADIGE, M.R., et al. ING2 PHD domain links histone H3 lystine 4 methylation to active gene repression. Nature 442, 96-99.
49. SINGAL, R., GINDER, G.D. (1999). DNA methylation. Blood 93, 4059-4070.
50. SZYF, M., BOZOVIC, V., and TANIGAWA, G. (1991). Growth regulation of mouse DNA methyltransferase gene expression. J. Biol. Chem. 266, 10027-10030.
51. TACHIBANA, M., SUGIMOTO, K., NOZAKI, M., UEDA, J., OHTA, T., OHKI, M., FUKUDA, M., TAKEDA, N., NIIDA, H., KATO, H., et al. (2002). G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis. Genes Dev. 16, 1779-1791.
52. TKACHUK, D.C., KOHLER, S., and CLEARY, M.L. (1992). Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias. Cell 71, 691-700.
53. TRIPOULAS, N., LAJEUNESSE, D., GILDEA, J., and SHEARN, A. (1996). The Drosophila ash1 gene product, which is localized at specific sites on polytene chromosomes, contains a SET domain and a PHD finger. Genetics 143, 913-928.
54. TUCKER, K.A., LILLY, M.B., HECK, L., and RADO, T.A. (1987). Characterization of a new human diploid myeloid leukemia cell line (PLB-985) with granulocytic and monocytic differentiating capacity. Blood 70, 372-378.
55. VOO, K.S., CARLONE, D.L., JACOBSEN, B.M., FLODIN, A., and SKALNIK, D.G. (2000). Cloning of a mammalian transcriptional activator that binds unmethylated CpG motifs and shares a CXXC domain with DNA methyltransferase, human trithorax, and methyl-CpG binding domain protein 1. Mol. Cell. Biol. 20, 2108-2121.
56. WYSOCKA, J., SWIGUT, T., XIAO, H., MILNE, T.A., KWON, S.Y., LANDRY, J., KAUER, M., TACKETT, A.J., CHAIT, B.T., BADENHORST, P., et al. (2006). A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling. Nature 442, 86-90.
57. YOUNG, S.R.L., MUMAW, C., MARRS, J.A., and SKALNIK, D.G. (2006). Antisense targeting of CXXC finger protein 1 inhibits genomic cytosine methylation and primitive hematopoiesis in zebrafish. J. Biol. Chem. 281, 37034-37044.
58. ZELEZNIK-LE, N., HARDEN, A.M., and ROWLEY, J.D. (1994). 11q23 translocations split the "AT-hook" cruciform DNA-binding region and the transcriptional repression domain from the activation domain of the mixed-lineage leukemia (MLL) gene. Proc. Natl. Acad. Sci. USA 91, 10610-10614.
59. ZHEN, L., KING, A.A.J., XIAO, Y., CHANOCK, S.J., ORKIN, S.H., and DINAUER, M.C. (1993). Gene targeting of X chromosome-linked chronic granulomatous disease locus in a human myeloid leukemia cell line and rescue by expression of recombinant gp91 phox. Proc. Natl. Acad. Sci. USA 90, 9832-9836.