The Drosophila ash1 gene product, which is localized at specific sites on polytene chromosomes, contains a SET domain and a PHD finger

Genetics

Volumn 143, Issue 2, 1996, Pages 913-928

  Tripoulas, Nicholas ^a,b   LaJeunesse, Dennis ^a,c   Gildea, John ^a   Shearn, Allen ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c DUKE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; GENE PRODUCT;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; CONTROLLED STUDY; DROSOPHILA; GENE MUTATION; HOMEOBOX; IMAGINAL DISC; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; POLYTENE CHROMOSOME; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REVIEW; SALIVARY GLAND;

AMINO ACID SEQUENCE; ANIMALS; CHROMOSOME MAPPING; CHROMOSOMES; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; MOLECULAR SEQUENCE DATA; MUTATION; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; TRANSCRIPTION FACTORS;

ANIMALIA;

EID: 0029994549     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (54)

1. AASLAND, R., T. J. GIBSON and A. F. STEWART, 1995 The PHD finger: implications for chromatin mediated transcriptional regulation. Trends Biochem. Sci. 20: 56-59.
2. AKAM, M., 1987 The molecular basis for metameric pattern in the Drosophila embryo. Development 101: 1-22.
3. ALTSCHUL, S. F., W. GISH, W. MILLER, E. W. MYERS and D. J. LIPMAN, 1990 Basic local alignment search tool. J. Mol. Biol. 215: 404-410.
4. ASHBURNER, M., 1989 Drosophila: A laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
5. BAIROCH, A., 1992 PROSITE: a dictionary of sites and patterns in proteins. Nucleic Acids Res. 20: (Supplement) 2013-2018.
6. BIENZ, M., and G. TREMML, 1988 Domain of Ultrabithorax expression in Drosophila visceral mesoderm from autoregulation and exclusion. Nature 333: 576-578.
7. BREEN, T. R., and P. J. HARTE, 1991 Molecular characterization of the trithorax gene, a positive regulator of homeotic gene expression in Drosophila. Mech. Dev. 35: 113-127.
8. BREEN, T. R., and P. J. HARTE, 1993 trithorax regulates multiple homeotic genes in the bithorax and Antennapedia complexes and exerts different tissue-specific, parasegment-specific and promoter-specific effects on each. Development 117: 119-134.
9. BROWER, D. L., 1987 Ultrabithorax gene expression in Drosophila imaginal discs and larval nervous system. Development 101: 83-92.
10. CAVENER, D. R., 1987 Comparison of the consensus sequence flanking translation start sites in Drosophila and vertebrates. Nucleic Acids Res. 15: 1353-1361.
11. CHINWALLA, V., E. P. JANE, and P. J. HARTE, 1995 In vivo chromosome sites of trithorax, a regulator of the homeotic genes in Drosophila. EMBO J. 14: 2056-2065.
12. DECAMILLIS, M., C. NIANSHENG, D. PIERRE and H. W. BROCK, 1992 The polyhomeotic gene of Drosophila encodes a chromatin protein that shares polytene chromosome-binding sites with Polycomb. Genes Dev. 6: 223-232.
13. DINGWALL, C., and R. A. LASKEY, 1991 Nuclear targeting sequences - a consensus? Trends Biochem Sci. 16: 478-481.
14. DJABALI, M., L. SELLERI, P. PARRY, M. BOWER, B. D. YOUNG et al., 1992 A trithorax like gene is interrupted by 11q23 translocations in acute leukemias. Nature Genet. 2: 112-118.
15. FUCHS, R., 1991 MacPattern: protein pattern searching on the Apple Macintosh. Comput. Applic. Biosci. 5: 227-232.
16. GU, Y., T. NAKAMURA, H. ADLER, R. PRASAD, O. CANAANI et al., 1992 The t(4; 11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene. Cell 71: 701-708.
17. HAFEN, E., M. LEVINE and W. J. GEHRING, 1984 Regulation of Antennapedia transcript distribution by the bithorax complex in Drosophila. Nature 307: 287-289.
18. HOEY, T., and M. LEVINE, 1988 Divergent homeo box proteins recognize similar DNA sequences in Drosophila. Nature 332: 858-861.
19. HOOVER, K. K., A. J. CHIEN and V. G. CORCES, 1993 Effects of transposable elements on the expression of the forked gene of Drosophila melanogaster. Genetics 135: 507-526.
20. HULTMARK, D., R. KLEMENZ, and W. GEHRING, 1986 Translational and transcriptional control elements in the untranslated leader of the heat shock gene hsp22. Cell 44: 429-438.
21. JONES, R. S., and W. M. GELBART, 1990 Genetic analysis of the Enhancer of zeste locus and its role in gene regulation in Drosophila melanogaster. Genetics 126: 185-199.
22. JONES, R. S., and W. M. GELBART, 1993 The Drosophila polycomb group gene Enhancer of zeste contains a region with sequence similarity to trithorax. Mol. Cell. Biol. 13: 6357-6366.
23. KENNISON, J. A., and J. W. TAMKUN, 1988 Dosage-dependent modifiers of Polycomb and Antennapedia mutations in Drosophila. Proc. Natl. Acad. Sci. USA 85: 8136-8140.
24. KRASNOW, M. A., E. E. SAFFMAN, K. KORNFELD and D. S. HOGNESS, 1989 Transcriptional activation and repression by Ultrabithorax proteins in cultured Drosophila cells. Cell 57: 1031-1043.
25. KUZIN, B., S. TILLIB, Y. SEDKOV, L. MIZROKHI and A. MAZO, 1994 The Drosophila trithorax gene encodes a chromosomal protein and directly regulates the region-specific homeotic gene fork head. Genes Dev. 8: 24787-2490.
26. KUZIORA, M. A., and W. MCGINNIS, 1988 Autoregulation of a Drosophila homeotic selector gene. Cell 55: 477-485.
27. LAJEUNESSE, D., 1995 Trans-regulation of the Drosophila homeotic selector genes by three trithorax group genes. PhD thesis. The Johns Hopkins University.
28. LAJEUNESSE, D., and A. SHEARN, 1995 Trans-regulation of thoracic homeotic selector genes of the Antennapedia and bithorax complexes by the trithorax group genes: absent, small, and homeotic discs 1 and 2. Mech. Dev. 53: 123-139.
29. LAJEUNESSE, D., and A. SHEARN, 1996 E(z): a Polycomb group gene or a trithorax group gene? Development (in press).
30. LINDSLEY, D. L., and G. G. ZIMM, 1992 The genome of Drosophila melanogaster. Academic Press, San Diego.
31. LONIE, A., R. D'ANDREA, R. PARO and R. SAINT, 1994 Molecular characterization of the Polycomblike gene of Drosophila melanogaster, a trans-acting negative regulator of homeotic gene expression. Development 120: 2629-2636.
32. MARTIN, E. C., and P. N. ADLER, 1993 The Polycomb group gene Posterior Sex Combs encodes a chromosomal protein. Development 117: 641-655.
33. MAZO, A. M., D.-H. HUANG, B. A. MOZER and I. B. DAWID, 1990 The trithorax gene, a trails-acting regulator of the bithorax complex in Drosophila, encodes a protein with zinc-binding domains. Proc. Natl. Acad. Sci. USA 87: 2112-2116.
34. MILNER, C. M., and R. D. CAMPBELL, 1993 The G9A gene in the human major histocompatibility complex encodes a novel protein containing ankyrin-like repeats. Biochem. J. 290: 811-818.
35. MOUNT, S. M., C. BURKS, G. HERTZ, G. D. STORMO, O. WHITE et al., 1992 Splicing signals in Drosophila: intron size, information content, and consensus sequences. Nucleic Acids Res. 20: 4255-4262.
36. PARO, R., 1990 Imprinting a determined state into the chromatin of Drosophila. Trends Genet. 6: 416-421.
37. PHILLIPS, M. D., and A. SHEARN, 1990 Mutations in polycombeotic, a Drosophila polycomb group gene, causes a wide range of maternal and zygotic phenotypes. Genetics 125: 91-101.
38. RASTELLI, L., C. S. CHAN and V. PIROTTA, 1993 Related chromosome binding sites for zeste, suppressors of zeste and Polycomb group proteins in Drosophila and their dependence on Enhancer of zeste function. EMBO J. 12: 1513-1522.
39. RECHSTEINER, M., 1990 PEST sequences are signals for rapid intranuclear proteolysis. Sem. Cell Biol. 1: 433-440.
40. REEVES, R., and M. S. NISSEN, 1990 The AT DNA-binding domain of mammalian high mobility group I proteins. A novel peptide motif for recognizing DNA structure. J. Biol. Chem. 265: 8573-8582.
41. ROGERS, S., R. WELLS and M. RECHSTEINER, 1986 Amino acid sequences common to rapidly degraded protein: the PEST hypothesis. Science 234: 364-368.
42. SCHINDLER, U., H. BECKMANN and A. CASHMORE, 1993 HAT3.1, a novel Arabidopsis homeodomain protein containing a conserved cysteine-rich region. Plant J. 4: 137-150.
43. SEDKOV, Y., S. TILLIB, L. MIZROKHI and A. MAZO, 1994 The bithorax complex is regulated by trithorax earlier during Drosophila embryogenesis than is the Antennapedia complex, correlating with a bithorax-like expression pattern of distinct early trithorax transcripts. Development 120: 1907-1917.
44. SHEARN, A., 1989 The ash1, ash2 and trithorax genes of Drosophila melanogaster are functionally related. Genetics 121: 517-525.
45. SHEARN, A., T. RICE, A. GAREN and W. GEHRING, 1971 Imaginai disc abnormalities in lethal mutants of Drosophila. Proc. Natl. Acad. Sci. USA 68: 2695-2698.
46. SHEARN, A., E. HERSPERGER and G. HERSPERGER, 1987 Genetic studies of mutations at two loci of Drosophila melanogaster which cause a wide variety of homeotic transformations. Roux's Arch. Dev. Biol. 196: 231-242.
47. STASSEN, M. J., D. BAILEY, S. FOX, V. CHINWALLA and P. J. HARTE, 1995 The Drosophila trithorax proteins contain a novel variant of the nuclear receptor type DNA binding domain and an ancient conserved motif found in other chromosomal proteins. Mech. Dev. 52: 1-15.
48. STEELE, F. R., T. WASHBURN, R. RIEGER and J. E. O'TOUSA, 1992 Drosophila retinal degeneration C (rdgC) encodes a novel serine/ threonine protein phosphatase. Cell 69: 669-676.
49. TAMKUN, J. W., R. DEURING, M. P. SCOTT, M. KISSINGER, A. M. PATTATUCCI et al., 1992 brahma: A regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SW12. Cell 68: 561-572.
50. TKACHUK, D. C., S. KOHLER and M. L. CLEARY, 1992 Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias. Cell 71: 691-700.
51. TRIPOULAS, N. A., E. HERSPERGER, D. LAJEUNESSE and A. SHEARN, 1994 Molecular genetic analysis of the Drosophila melanogaster gene absent, small or homeotic discs1 (ash1). Genetics 137: 1027-1038.
52. TSCHIERSCH, B., A. HOFMANN, V. KRAUSS, R. DORN, G. KORGE et al., 1994 The protein encoded by the Drosophila position-effect variegation suppressor gene Su(var) 3-9 combines domains of antagonistic regulators of homeotic gene complexes. EMBO J. 13: 3822-3831.
53. WEEKS, J. R., S. E. HARDIN, J. SHEN, J. M. LEE and A. GREENLEAF, 1993 Locus-specific variation in phosphorylation state of RNA polymerase II in vivo: correlations with gene activity and transcript processing. Genes Dev. 7: 23298-2344.
54. ZINK, B., and R. PARO, 1989 In vivo binding of a trans-regulator of homeotic genes in Drosophila melanogaster. Nature 337: 468-471.